WP_NIPBL_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CBX3 Chromobox protein homolog 3 [1] -0.75[2] -0.85[3] -0.88[4] -0.85[5] -0.84[6] -2.93[7]
2 RNF8 E3 ubiquitin-protein ligase RNF8 [8] 1.09[9] 0.25[10] -1.21[11] 0.33[12] -0.09[13] -0.84[14]
3 RNF168 E3 ubiquitin-protein ligase RNF168 [15] 0.14[16] -0.12[17] 0.76[18] -0.87[19] 0.38[20] 1.34[21]
4 NIPBL Nipped-B-like protein [22] 0.67[23] 1.79[24] 2.24[25] 1.75[26] 1.96[27] 2.76[28]
5 MDC1 Mediator of DNA damage checkpoint protein 1 [29] 2.24[30] 1.73[31] 1.96[32] 1.94[33] 1.96[34] 0.70[35]
6 ATR Serine/threonine-protein kinase ATR [36] 0.85[37] 0.93[38] 0.90[39] 1.58[40] 1.64[41] 2.80[42]
7 ATM Serine-protein kinase ATM [43] 2.78[44] 3.48[45] 3.08[46] 3.21[47] 2.78[48] 4.24[49]
8 H2AX [50] [51] [52] [53] [54] [55] [56]
[1]
ref_hepatocyte CBX3
Mean 48
Standard deviation 31
Values 20 23 39 66 92
[2]
HepG2 CBX3
Mean 74.6
Standard deviation 22
Values 90 59
[3]
HepG2.C3A CBX3
Mean 117
Standard deviation 52
Values 1.5e+02 80
[4]
HuH.7 CBX3
Mean 119
Standard deviation 38
Values 1.5e+02 79 1.3e+02
[5]
SNU475 CBX3
Mean 94.8
Standard deviation 0.72
Values 95 94
[6]
THLE CBX3
Mean 99.9
Standard deviation 9.9
Values 93 1.1e+02
[7]
liver CBX3
Mean 15
Standard deviation 6.9
Values 7.5 11 23 19
[8]
ref_hepatocyte RNF8
Mean 3.22
Standard deviation 2.5
Values 2.2 1 1.5 6.9 4.6
[9]
HepG2 RNF8
Mean 18
Standard deviation 2.4
Values 20 16
[10]
HepG2.C3A RNF8
Mean 16.9
Standard deviation 0.047
Values 17 17
[11]
HuH.7 RNF8
Mean 6.38
Standard deviation 0.46
Values 6.6 6.7 5.8
[12]
SNU475 RNF8
Mean 14.3
Standard deviation 0.79
Values 15 14
[13]
THLE RNF8
Mean 11.2
Standard deviation 0.72
Values 11 12
[14]
liver RNF8
Mean 4.3
Standard deviation 0.98
Values 3.2 3.9 5.5 4.6
[15]
ref_hepatocyte RNF168
Mean 2.39
Standard deviation 0.84
Values 2.7 1.8 1.2 3.1 3.1
[16]
HepG2 RNF168
Mean 6.93
Standard deviation 1.4
Values 7.9 5.9
[17]
HepG2.C3A RNF168
Mean 9.67
Standard deviation 0.69
Values 9.2 10
[18]
HuH.7 RNF168
Mean 18.4
Standard deviation 3.1
Values 16 18 22
[19]
SNU475 RNF168
Mean 4.63
Standard deviation 0.52
Values 5 4.3
[20]
THLE RNF168
Mean 11.6
Standard deviation 0.93
Values 11 12
[21]
liver RNF168
Mean 14.5
Standard deviation 2.9
Values 11 13 15 18
[22]
ref_hepatocyte NIPBL
Mean 2.08
Standard deviation 0.47
Values 2.6 1.8 1.4 2.3 2.2
[23]
HepG2 NIPBL
Mean 8.66
Standard deviation 2.4
Values 10 7
[24]
HepG2.C3A NIPBL
Mean 31.6
Standard deviation 1.1
Values 32 31
[25]
HuH.7 NIPBL
Mean 44.7
Standard deviation 12
Values 31 55 49
[26]
SNU475 NIPBL
Mean 24.9
Standard deviation 4.4
Values 28 22
[27]
THLE NIPBL
Mean 30.2
Standard deviation 13
Values 39 21
[28]
liver NIPBL
Mean 33.5
Standard deviation 13
Values 42 48 25 20
[29]
ref_hepatocyte MDC1
Mean 2.03
Standard deviation 1.1
Values 2.9 1.1 1.1 3.5 1.6
[30]
HepG2 MDC1
Mean 25.1
Standard deviation 0.18
Values 25 25
[31]
HepG2.C3A MDC1
Mean 29.6
Standard deviation 2.6
Values 31 28
[32]
HuH.7 MDC1
Mean 35.9
Standard deviation 14
Values 34 23 51
[33]
SNU475 MDC1
Mean 27.7
Standard deviation 2.6
Values 30 26
[34]
THLE MDC1
Mean 29.5
Standard deviation 7.6
Values 24 35
[35]
liver MDC1
Mean 7.87
Standard deviation 1.2
Values 9.1 6.3 7.8 8.2
[36]
ref_hepatocyte ATR
Mean 1.48
Standard deviation 0.93
Values 0.87 0.82 1.1 1.5 3.1
[37]
HepG2 ATR
Mean 6.99
Standard deviation 2.6
Values 8.9 5.1
[38]
HepG2.C3A ATR
Mean 12.4
Standard deviation 3
Values 15 10
[39]
HuH.7 ATR
Mean 12.6
Standard deviation 3.2
Values 11 10 16
[40]
SNU475 ATR
Mean 15.7
Standard deviation 0.082
Values 16 16
[41]
THLE ATR
Mean 17.2
Standard deviation 1.5
Values 18 16
[42]
liver ATR
Mean 24.7
Standard deviation 14
Values 28 43 13 15
[43]
ref_hepatocyte ATM
Mean 0.969
Standard deviation 0.7
Values 0.27 1.1 0.7 2.1 0.69
[44]
HepG2 ATM
Mean 17.5
Standard deviation 8.3
Values 23 12
[45]
HepG2.C3A ATM
Mean 47.4
Standard deviation 4.5
Values 51 44
[46]
HuH.7 ATM
Mean 37.5
Standard deviation 9.1
Values 27 44 41
[47]
SNU475 ATM
Mean 31.7
Standard deviation 8.2
Values 26 38
[48]
THLE ATM
Mean 24.9
Standard deviation 4.4
Values 28 22
[49]
liver ATM
Mean 43.7
Standard deviation 31
Values 64 76 17 17
[50]
ref_hepatocyte H2AX
Missing
[51]
HepG2 H2AX
Missing
[52]
HepG2.C3A H2AX
Missing
[53]
HuH.7 H2AX
Missing
[54]
SNU475 H2AX
Missing
[55]
THLE H2AX
Missing
[56]
liver H2AX
Missing