WP_NEURODEGENERATION_WITH_BRAIN_IRON_ACCUMULATION_NBIA_SUBTYPES_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FTL Ferritin light chain [1] -0.20[2] -0.60[3] -0.61[4] -0.04[5] -0.73[6] -0.50[7]
2 CP Ceruloplasmin [8] -1.52[9] 1.59[10] 0.37[11] -3.95[12] -8.04[13] 2.50[14]
3 SCP2 Non-specific lipid-transfer protein [15] -1.80[16] -0.66[17] -0.10[18] -2.06[19] -0.57[20] 1.10[21]
4 RHEB GTP-binding protein Rheb [22] 0.09[23] 0.67[24] 0.90[25] 0.26[26] 2.03[27] -0.32[28]
5 COASY Bifunctional coenzyme A synthase [29] 2.37[30] 3.39[31] 2.53[32] 0.33[33] 2.18[34] 0.37[35]
6 BECN1 Beclin-1 [36] 1.20[37] 0.99[38] 1.24[39] 0.02[40] 1.64[41] -0.29[42]
7 ATG3 Ubiquitin-like-conjugating enzyme ATG3 [43] -0.29[44] 0.25[45] 1.10[46] -0.27[47] 2.07[48] -0.39[49]
8 AKT1S1 Proline-rich AKT1 substrate 1 [50] 1.58[51] 1.43[52] 2.08[53] 0.62[54] 2.89[55] -0.42[56]
9 SPTLC1 Serine palmitoyltransferase 1 [57] 2.20[58] 2.89[59] 2.50[60] 1.71[61] 4.00[62] -0.06[63]
10 WDR45 WD repeat domain phosphoinositide-interacting protein 4 [64] 0.57[65] 1.25[66] 1.43[67] 0.74[68] 2.23[69] 0.94[70]
11 STK11 Serine/threonine-protein kinase STK11 [71] 1.95[72] 1.91[73] 2.45[74] 0.66[75] 2.66[76] -0.09[77]
12 ATG16L1 Autophagy-related protein 16-1 [78] 2.08[79] 2.12[80] 1.70[81] 1.03[82] 2.18[83] 0.15[84]
13 PANK2 Pantothenate kinase 2, mitochondrial [85] 2.18[86] 2.26[87] 1.70[88] 1.08[89] 2.45[90] -0.37[91]
14 MLST8 Target of rapamycin complex subunit LST8 [92] 1.87[93] 2.20[94] 2.87[95] 0.39[96] 2.39[97] 0.20[98]
15 WIPI1 WD repeat domain phosphoinositide-interacting protein 1 [99] 2.14[100] 3.01[101] 2.39[102] 0.14[103] 2.50[104] 0.82[105]
16 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 [106] 2.67[107] 2.80[108] 3.21[109] 1.46[110] 4.00[111] 1.59[112]
17 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 [113] 1.95[114] 3.24[115] 5.06[116] 2.83[117] 4.75[118] 2.83[119]
18 C19orf12 Protein C19orf12 [120] 1.87[121] 1.85[122] 2.38[123] 0.97[124] 1.82[125] 1.99[126]
19 ATG4A Cysteine protease ATG4A [127] -0.01[128] 0.39[129] 1.08[130] -0.08[131] 2.08[132] 0.87[133]
20 MAP1LC3A Microtubule-associated proteins 1A/1B light chain 3A [134] -7.00[135] -8.44[136] -7.51[137] -1.87[138] 1.73[139] -0.17[140]
21 GTPBP2 GTP-binding protein 2 [141] 3.42[142] 3.74[143] 2.87[144] 2.57[145] 4.36[146] -0.06[147]
22 ATG5 Autophagy protein 5 [148] 1.82[149] 2.85[150] 2.81[151] 2.15[152] 3.54[153] 1.61[154]
23 ATG13 Autophagy-related protein 13 [155] 4.08[156] 4.05[157] 4.59[158] 1.50[159] 4.24[160] 2.61[161]
24 ATG12 Ubiquitin-like protein ATG12 [162] 2.47[163] 3.37[164] 3.61[165] 2.83[166] 4.25[167] 2.20[168]
25 MECP2 Methyl-CpG-binding protein 2 [169] 2.76[170] 3.06[171] 3.57[172] 2.95[173] 4.71[174] 1.60[175]
26 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [176] 2.42[177] 3.06[178] 2.44[179] 2.17[180] 4.03[181] 1.40[182]
27 MTOR Serine/threonine-protein kinase mTOR [183] 4.57[184] 5.59[185] 5.46[186] 4.05[187] 5.78[188] 4.22[189]
28 RB1CC1 RB1-inducible coiled-coil protein 1 [190] 2.32[191] 5.13[192] 4.44[193] 3.70[194] 4.88[195] 3.63[196]
29 TSC2 Tuberin [197] 3.85[198] 3.39[199] 4.37[200] 2.57[201] 4.74[202] 2.85[203]
30 ULK1 Serine/threonine-protein kinase ULK1 [204] 3.35[205] 3.63[206] 5.14[207] 3.34[208] 4.34[209] 2.66[210]
31 ACACA Acetyl-CoA carboxylase 1 [211] 4.49[212] 4.84[213] 6.06[214] 3.95[215] 4.79[216] 4.12[217]
32 DEPTOR DEP domain-containing mTOR-interacting protein [218] -1.28[219] -0.09[220] 4.26[221] -2.88[222] 1.41[223] 1.62[224]
33 ATP13A2 Cation-transporting ATPase 13A2 [225] 4.29[226] 4.10[227] 2.00[228] 3.47[229] 4.58[230] 0.54[231]
34 ATG14 Beclin 1-associated autophagy-related key regulator [232] 2.76[233] 3.32[234] 3.74[235] 2.83[236] 4.25[237] 1.51[238]
35 ATG2A Autophagy-related protein 2 homolog A [239] 3.57[240] 3.73[241] 4.34[242] 2.89[243] 4.85[244] 3.54[245]
36 ATG7 Ubiquitin-like modifier-activating enzyme ATG7 [246] 3.03[247] 2.55[248] 3.58[249] 2.05[250] 4.56[251] 2.53[252]
37 RPTOR Regulatory-associated protein of mTOR [253] 5.12[254] 4.37[255] 4.77[256] 3.22[257] 5.10[258] 3.10[259]
38 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [260] 3.20[261] 3.27[262] 4.54[263] 3.03[264] 5.16[265] 3.64[266]
39 ATG10 Ubiquitin-like-conjugating enzyme ATG10 [267] 1.51[268] 1.89[269] 2.44[270] 1.62[271] 2.41[272] 0.94[273]
40 TSC1 Hamartin [274] 3.93[275] 4.60[276] 5.04[277] 3.43[278] 5.29[279] 3.52[280]
41 DCAF17 DDB1- and CUL4-associated factor 17 [281] 3.29[282] 4.85[283] 3.86[284] 2.77[285] 4.44[286] 1.96[287]
42 PLA2G6 85/88 kDa calcium-independent phospholipase A2 [288] 2.09[289] 4.53[290] 5.17[291] 1.21[292] 2.92[293] 2.41[294]
43 FA2H Fatty acid 2-hydroxylase [295] 2.91[296] 2.59[297] 0.62[298] 0.28[299] 1.11[300] 1.18[301]
44 ATG101 Autophagy-related protein 101 [302] [303] [304] [305] [306] [307] [308]
[1]
ref_hepatocyte FTL
Mean 6.65e+03
Standard deviation 4e+03
Values 2.9e+03 1.1e+04 1.1e+04 5.1e+03 3.5e+03
[2]
HepG2 FTL
Mean 3.12e+03
Standard deviation 7.3e+02
Values 2.6e+03 3.6e+03
[3]
HepG2.C3A FTL
Mean 2.09e+03
Standard deviation 7.1e+02
Values 2.6e+03 1.6e+03
[4]
HuH.7 FTL
Mean 1.61e+03
Standard deviation 1.7e+02
Values 1.7e+03 1.4e+03 1.7e+03
[5]
SNU475 FTL
Mean 4.59e+03
Standard deviation 6.3e+02
Values 4.1e+03 5e+03
[6]
THLE FTL
Mean 1.02e+03
Standard deviation 75
Values 9.6e+02 1.1e+03
[7]
liver FTL
Mean 3.93e+03
Standard deviation 4.2e+03
Values 3.1e+02 6.9e+02 5.7e+03 9e+03
[8]
ref_hepatocyte CP
Mean 263
Standard deviation 3.3e+02
Values 25 6.5e+02 6.1e+02 11 21
[9]
HepG2 CP
Mean 49.3
Standard deviation 5.3
Values 45 53
[10]
HepG2.C3A CP
Mean 376
Standard deviation 60
Values 3.3e+02 4.2e+02
[11]
HuH.7 CP
Mean 126
Standard deviation 95
Values 64 2.4e+02 79
[12]
SNU475 CP
Mean 12.1
Standard deviation 0.56
Values 12 12
[13]
THLE CP
Mean 0.253
Standard deviation 0.027
Values 0.27 0.23
[14]
liver CP
Mean 1.24e+03
Standard deviation 9.4e+02
Values 8.8e+02 2.6e+03 4.5e+02 1e+03
[15]
ref_hepatocyte SCP2
Mean 227
Standard deviation 2.8e+02
Values 9.1 7.1e+02 2e+02 1.4e+02 77
[16]
HepG2 SCP2
Mean 35
Standard deviation 12
Values 43 27
[17]
HepG2.C3A SCP2
Mean 68.2
Standard deviation 19
Values 82 55
[18]
HuH.7 SCP2
Mean 78.3
Standard deviation 13
Values 89 63 83
[19]
SNU475 SCP2
Mean 38.6
Standard deviation 10
Values 32 46
[20]
THLE SCP2
Mean 38.9
Standard deviation 1.4
Values 40 38
[21]
liver SCP2
Mean 407
Standard deviation 2e+02
Values 2.8e+02 2.1e+02 6.5e+02 4.9e+02
[22]
ref_hepatocyte RHEB
Mean 67.3
Standard deviation 38
Values 1.1e+02 33 29 64 96
[23]
HepG2 RHEB
Mean 38.6
Standard deviation 1.7
Values 37 40
[24]
HepG2.C3A RHEB
Mean 51.2
Standard deviation 9.4
Values 58 45
[25]
HuH.7 RHEB
Mean 46.6
Standard deviation 5.3
Values 53 44 44
[26]
SNU475 RHEB
Mean 57.5
Standard deviation 1.9
Values 56 59
[27]
THLE RHEB
Mean 69.7
Standard deviation 5.7
Values 66 74
[28]
liver RHEB
Mean 44.9
Standard deviation 28
Values 18 25 77 59
[29]
ref_hepatocyte COASY
Mean 27.4
Standard deviation 9.2
Values 28 27 40 27 14
[30]
HepG2 COASY
Mean 76.2
Standard deviation 9.1
Values 70 83
[31]
HepG2.C3A COASY
Mean 136
Standard deviation 28
Values 1.2e+02 1.6e+02
[32]
HuH.7 COASY
Mean 58.8
Standard deviation 12
Values 64 45 67
[33]
SNU475 COASY
Mean 24.4
Standard deviation 2.3
Values 23 26
[34]
THLE COASY
Mean 31.5
Standard deviation 0.16
Values 31 32
[35]
liver COASY
Mean 29.4
Standard deviation 24
Values 10 7.7 53 46
[36]
ref_hepatocyte BECN1
Mean 26.6
Standard deviation 14
Values 21 14 17 47 34
[37]
HepG2 BECN1
Mean 32.9
Standard deviation 2.3
Values 35 31
[38]
HepG2.C3A BECN1
Mean 25.2
Standard deviation 4.8
Values 29 22
[39]
HuH.7 BECN1
Mean 23.3
Standard deviation 2.3
Values 23 21 26
[40]
SNU475 BECN1
Mean 19.1
Standard deviation 2
Values 18 21
[41]
THLE BECN1
Mean 21.1
Standard deviation 3.3
Values 19 23
[42]
liver BECN1
Mean 18.2
Standard deviation 8.1
Values 9.2 14 23 27
[43]
ref_hepatocyte ATG3
Mean 23.7
Standard deviation 8.8
Values 17 22 22 19 39
[44]
HepG2 ATG3
Mean 10.5
Standard deviation 2.5
Values 12 8.7
[45]
HepG2.C3A ATG3
Mean 13.4
Standard deviation 2.5
Values 15 12
[46]
HuH.7 ATG3
Mean 18.8
Standard deviation 4.5
Values 23 14 19
[47]
SNU475 ATG3
Mean 14
Standard deviation 1.3
Values 15 13
[48]
THLE ATG3
Mean 25.3
Standard deviation 2.1
Values 24 27
[49]
liver ATG3
Mean 15.1
Standard deviation 7.5
Values 7.6 10 19 24
[50]
ref_hepatocyte AKT1S1
Mean 16.3
Standard deviation 7.1
Values 22 16 25 9.3 9.6
[51]
HepG2 AKT1S1
Mean 26.1
Standard deviation 2.4
Values 28 24
[52]
HepG2.C3A AKT1S1
Mean 20.9
Standard deviation 0.11
Values 21 21
[53]
HuH.7 AKT1S1
Mean 25.6
Standard deviation 5
Values 27 20 30
[54]
SNU475 AKT1S1
Mean 17.8
Standard deviation 0.54
Values 17 18
[55]
THLE AKT1S1
Mean 30.7
Standard deviation 8
Values 25 36
[56]
liver AKT1S1
Mean 10.2
Standard deviation 7
Values 4.2 4.3 14 18
[57]
ref_hepatocyte SPTLC1
Mean 13.7
Standard deviation 9.5
Values 10 7.7 5.2 29 16
[58]
HepG2 SPTLC1
Mean 33.9
Standard deviation 2.4
Values 36 32
[59]
HepG2.C3A SPTLC1
Mean 48.2
Standard deviation 6.8
Values 53 43
[60]
HuH.7 SPTLC1
Mean 28.8
Standard deviation 0.78
Values 28 30 28
[61]
SNU475 SPTLC1
Mean 31.8
Standard deviation 5.1
Values 28 35
[62]
THLE SPTLC1
Mean 55.7
Standard deviation 4
Values 53 59
[63]
liver SPTLC1
Mean 10.9
Standard deviation 1.2
Values 9.6 10 12 12
[64]
ref_hepatocyte WDR45
Mean 13
Standard deviation 9.3
Values 15 14 27 2.8 6
[65]
HepG2 WDR45
Mean 10.4
Standard deviation 1.6
Values 9.3 12
[66]
HepG2.C3A WDR45
Mean 14.7
Standard deviation 5.9
Values 10 19
[67]
HuH.7 WDR45
Mean 13
Standard deviation 2.3
Values 13 15 11
[68]
SNU475 WDR45
Mean 15.5
Standard deviation 1.9
Values 14 17
[69]
THLE WDR45
Mean 15.5
Standard deviation 1.9
Values 14 17
[70]
liver WDR45
Mean 20.8
Standard deviation 14
Values 8.9 9.4 35 30
[71]
ref_hepatocyte STK11
Mean 12.8
Standard deviation 5.7
Values 8 8.8 10 22 15
[72]
HepG2 STK11
Mean 26.5
Standard deviation 9.5
Values 20 33
[73]
HepG2.C3A STK11
Mean 22.8
Standard deviation 6.5
Values 18 27
[74]
HuH.7 STK11
Mean 25.9
Standard deviation 2.8
Values 29 23 26
[75]
SNU475 STK11
Mean 14.3
Standard deviation 1.5
Values 13 15
[76]
THLE STK11
Mean 20.5
Standard deviation 0.22
Values 21 20
[77]
liver STK11
Mean 9.97
Standard deviation 7.5
Values 16 17 3.6 3.3
[78]
ref_hepatocyte ATG16L1
Mean 12.4
Standard deviation 8.2
Values 14 3.3 4.1 20 20
[79]
HepG2 ATG16L1
Mean 28.1
Standard deviation 1.2
Values 29 27
[80]
HepG2.C3A ATG16L1
Mean 25.7
Standard deviation 3.4
Values 28 23
[81]
HuH.7 ATG16L1
Mean 14.9
Standard deviation 3.4
Values 19 12 14
[82]
SNU475 ATG16L1
Mean 18
Standard deviation 1.7
Values 19 17
[83]
THLE ATG16L1
Mean 14.2
Standard deviation 0.11
Values 14 14
[84]
liver ATG16L1
Mean 11.5
Standard deviation 2.5
Values 10 15 8.6 12
[85]
ref_hepatocyte PANK2
Mean 11.5
Standard deviation 9
Values 8.8 6.3 7.2 27 7.9
[86]
HepG2 PANK2
Mean 28.1
Standard deviation 4.2
Values 31 25
[87]
HepG2.C3A PANK2
Mean 26.3
Standard deviation 0.44
Values 27 26
[88]
HuH.7 PANK2
Mean 13.9
Standard deviation 3.5
Values 17 9.9 15
[89]
SNU475 PANK2
Mean 17.3
Standard deviation 0.65
Values 18 17
[90]
THLE PANK2
Mean 16
Standard deviation 2.4
Values 14 18
[91]
liver PANK2
Mean 7.46
Standard deviation 1.5
Values 8.4 8.9 6.6 5.8
[92]
ref_hepatocyte MLST8
Mean 10
Standard deviation 3.8
Values 14 10 14 7 5.5
[93]
HepG2 MLST8
Mean 19.6
Standard deviation 1.4
Values 19 21
[94]
HepG2.C3A MLST8
Mean 22
Standard deviation 3.6
Values 19 24
[95]
HuH.7 MLST8
Mean 27.2
Standard deviation 3.6
Values 30 23 28
[96]
SNU475 MLST8
Mean 9.36
Standard deviation 0.84
Values 8.8 9.9
[97]
THLE MLST8
Mean 13.3
Standard deviation 1.9
Values 12 15
[98]
liver MLST8
Mean 9.64
Standard deviation 7.6
Values 3.8 2.5 17 15
[99]
ref_hepatocyte WIPI1
Mean 8.86
Standard deviation 6.3
Values 20 4.8 8.4 6.6 4.8
[100]
HepG2 WIPI1
Mean 20.9
Standard deviation 6.8
Values 16 26
[101]
HepG2.C3A WIPI1
Mean 34.1
Standard deviation 20
Values 20 48
[102]
HuH.7 WIPI1
Mean 17.2
Standard deviation 2.1
Values 16 20 16
[103]
SNU475 WIPI1
Mean 6.93
Standard deviation 3.6
Values 4.4 9.4
[104]
THLE WIPI1
Mean 12.8
Standard deviation 0.36
Values 13 13
[105]
liver WIPI1
Mean 13.1
Standard deviation 4.7
Values 9 9.8 14 19
[106]
ref_hepatocyte WIPI2
Mean 8.61
Standard deviation 3.6
Values 15 7.8 7.3 5.1 8.3
[107]
HepG2 WIPI2
Mean 29.5
Standard deviation 1.6
Values 28 31
[108]
HepG2.C3A WIPI2
Mean 28.6
Standard deviation 2.4
Values 27 30
[109]
HuH.7 WIPI2
Mean 29.5
Standard deviation 2.8
Values 33 27 29
[110]
SNU475 WIPI2
Mean 16.8
Standard deviation 0.0027
Values 17 17
[111]
THLE WIPI2
Mean 35
Standard deviation 2.6
Values 33 37
[112]
liver WIPI2
Mean 21.7
Standard deviation 7.4
Values 16 15 31 24
[113]
ref_hepatocyte PRKAA1
Mean 8.04
Standard deviation 3.4
Values 6.1 14 7.2 5.4 7.6
[114]
HepG2 PRKAA1
Mean 16.8
Standard deviation 2.1
Values 18 15
[115]
HepG2.C3A PRKAA1
Mean 36.3
Standard deviation 5.5
Values 40 32
[116]
HuH.7 PRKAA1
Mean 99.5
Standard deviation 14
Values 84 1e+02 1.1e+02
[117]
SNU475 PRKAA1
Mean 40.7
Standard deviation 4.8
Values 37 44
[118]
THLE PRKAA1
Mean 55.1
Standard deviation 6.9
Values 60 50
[119]
liver PRKAA1
Mean 47.6
Standard deviation 7.3
Values 47 58 40 45
[120]
ref_hepatocyte C19orf12
Mean 7.98
Standard deviation 2.5
Values 4.2 8.8 7.4 11 8.3
[121]
HepG2 C19orf12
Mean 15.7
Standard deviation 1.4
Values 17 15
[122]
HepG2.C3A C19orf12
Mean 13.7
Standard deviation 0.86
Values 14 13
[123]
HuH.7 C19orf12
Mean 15.4
Standard deviation 1.1
Values 16 16 14
[124]
SNU475 C19orf12
Mean 11.1
Standard deviation 2.6
Values 9.3 13
[125]
THLE C19orf12
Mean 7.17
Standard deviation 0.2
Values 7 7.3
[126]
liver C19orf12
Mean 26.4
Standard deviation 5.9
Values 25 19 33 29
[127]
ref_hepatocyte ATG4A
Mean 7.65
Standard deviation 3.1
Values 8.6 7.2 11 2.7 8.8
[128]
HepG2 ATG4A
Mean 4.1
Standard deviation 1.6
Values 5.2 3
[129]
HepG2.C3A ATG4A
Mean 4.79
Standard deviation 1.3
Values 5.7 3.9
[130]
HuH.7 ATG4A
Mean 6
Standard deviation 0.58
Values 6.5 6.1 5.4
[131]
SNU475 ATG4A
Mean 5.15
Standard deviation 0.14
Values 5.1 5.2
[132]
THLE ATG4A
Mean 8.22
Standard deviation 0.48
Values 8.6 7.9
[133]
liver ATG4A
Mean 11.7
Standard deviation 4.4
Values 7.3 8.8 14 16
[134]
ref_hepatocyte MAP1LC3A
Mean 7.47
Standard deviation 7.7
Values 6.6 20 6.7 0.12 3.6
[135]
HepG2 MAP1LC3A
Mean 0.0315
Standard deviation 0.004
Values 0.034 0.029
[136]
HepG2.C3A MAP1LC3A
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[137]
HuH.7 MAP1LC3A
Mean 0.0152
Standard deviation 0.017
Values 0 0.013 0.033
[138]
SNU475 MAP1LC3A
Mean 1.45
Standard deviation 0.48
Values 1.1 1.8
[139]
THLE MAP1LC3A
Mean 6.29
Standard deviation 0.45
Values 6.6 6
[140]
liver MAP1LC3A
Mean 5.54
Standard deviation 6.3
Values 0.61 0.49 14 7.4
[141]
ref_hepatocyte GTPBP2
Mean 7.35
Standard deviation 6
Values 17 2.4 5.9 3.1 7.9
[142]
HepG2 GTPBP2
Mean 42.3
Standard deviation 26
Values 24 61
[143]
HepG2.C3A GTPBP2
Mean 46.9
Standard deviation 22
Values 31 63
[144]
HuH.7 GTPBP2
Mean 20
Standard deviation 3.2
Values 22 21 16
[145]
SNU475 GTPBP2
Mean 31
Standard deviation 1.3
Values 32 30
[146]
THLE GTPBP2
Mean 38.4
Standard deviation 6.5
Values 43 34
[147]
liver GTPBP2
Mean 5.87
Standard deviation 1.6
Values 6.7 7.2 5.8 3.7
[148]
ref_hepatocyte ATG5
Mean 6.42
Standard deviation 2
Values 6.5 8.3 8.4 4.4 4.5
[149]
HepG2 ATG5
Mean 12.2
Standard deviation 4.5
Values 15 9
[150]
HepG2.C3A ATG5
Mean 22.1
Standard deviation 5.1
Values 26 18
[151]
HuH.7 ATG5
Mean 16.7
Standard deviation 1.4
Values 18 16 16
[152]
SNU475 ATG5
Mean 20.3
Standard deviation 1.9
Values 19 22
[153]
THLE ATG5
Mean 19
Standard deviation 0.43
Values 19 19
[154]
liver ATG5
Mean 16.3
Standard deviation 4.6
Values 11 15 20 20
[155]
ref_hepatocyte ATG13
Mean 4.93
Standard deviation 1.7
Values 4.9 4.9 6.9 2.3 5.6
[156]
HepG2 ATG13
Mean 44.9
Standard deviation 2.2
Values 46 43
[157]
HepG2.C3A ATG13
Mean 39
Standard deviation 7.5
Values 34 44
[158]
HuH.7 ATG13
Mean 44.1
Standard deviation 2.3
Values 42 45 46
[159]
SNU475 ATG13
Mean 9.91
Standard deviation 1.8
Values 8.7 11
[160]
THLE ATG13
Mean 23.7
Standard deviation 4.2
Values 21 27
[161]
liver ATG13
Mean 25.1
Standard deviation 8.4
Values 19 17 32 33
[162]
ref_hepatocyte ATG12
Mean 4.73
Standard deviation 0.81
Values 3.6 4.5 4.5 5.6 5.4
[163]
HepG2 ATG12
Mean 14.1
Standard deviation 2.6
Values 16 12
[164]
HepG2.C3A ATG12
Mean 23.3
Standard deviation 1.9
Values 25 22
[165]
HuH.7 ATG12
Mean 21.4
Standard deviation 1.1
Values 23 21 20
[166]
SNU475 ATG12
Mean 23.9
Standard deviation 3.1
Values 22 26
[167]
THLE ATG12
Mean 22.9
Standard deviation 1.3
Values 22 24
[168]
liver ATG12
Mean 18.2
Standard deviation 8
Values 12 11 25 25
[169]
ref_hepatocyte MECP2
Mean 4.65
Standard deviation 3.2
Values 9 3.6 6.8 0.97 2.9
[170]
HepG2 MECP2
Mean 17
Standard deviation 0.35
Values 17 17
[171]
HepG2.C3A MECP2
Mean 18.5
Standard deviation 2.1
Values 17 20
[172]
HuH.7 MECP2
Mean 20.4
Standard deviation 2.7
Values 19 19 24
[173]
SNU475 MECP2
Mean 25.6
Standard deviation 3.5
Values 23 28
[174]
THLE MECP2
Mean 30.9
Standard deviation 2.7
Values 29 33
[175]
liver MECP2
Mean 11.7
Standard deviation 2.4
Values 14 9.6 14 9.8
[176]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 2.3 3 3.8 8 5.9
[177]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 16 11
[178]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 19 17
[179]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 7.5 11 9.1
[180]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 12 17
[181]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[182]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 11 15 6.9 6.8
[183]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[184]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[185]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[186]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[187]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[188]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[189]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[190]
ref_hepatocyte RB1CC1
Mean 3.31
Standard deviation 1.7
Values 1.7 2.1 2.6 5.6 4.5
[191]
HepG2 RB1CC1
Mean 8.89
Standard deviation 1.4
Values 9.9 7.9
[192]
HepG2.C3A RB1CC1
Mean 55.2
Standard deviation 1.3
Values 54 56
[193]
HuH.7 RB1CC1
Mean 26.6
Standard deviation 9.4
Values 21 37 22
[194]
SNU475 RB1CC1
Mean 30.5
Standard deviation 1.9
Values 29 32
[195]
THLE RB1CC1
Mean 24.7
Standard deviation 8.3
Values 31 19
[196]
liver RB1CC1
Mean 34.2
Standard deviation 7.1
Values 33 42 35 25
[197]
ref_hepatocyte TSC2
Mean 3.2
Standard deviation 0.13
Values 3.2 3.4 3.2 3.1 3.1
[198]
HepG2 TSC2
Mean 24.9
Standard deviation 3.4
Values 22 27
[199]
HepG2.C3A TSC2
Mean 16
Standard deviation 4.7
Values 13 19
[200]
HuH.7 TSC2
Mean 24.6
Standard deviation 4
Values 21 24 29
[201]
SNU475 TSC2
Mean 13.5
Standard deviation 5
Values 10 17
[202]
THLE TSC2
Mean 21.8
Standard deviation 1.7
Values 21 23
[203]
liver TSC2
Mean 19.2
Standard deviation 2.2
Values 22 19 17 18
[204]
ref_hepatocyte ULK1
Mean 3.19
Standard deviation 0.97
Values 3.8 2.7 4.6 2.2 2.6
[205]
HepG2 ULK1
Mean 17.5
Standard deviation 3
Values 15 20
[206]
HepG2.C3A ULK1
Mean 18.9
Standard deviation 12
Values 10 27
[207]
HuH.7 ULK1
Mean 41.8
Standard deviation 6.6
Values 38 49 38
[208]
SNU475 ULK1
Mean 23
Standard deviation 7.3
Values 18 28
[209]
THLE ULK1
Mean 16.5
Standard deviation 0.85
Values 16 17
[210]
liver ULK1
Mean 16.8
Standard deviation 11
Values 22 7.2 29 8.9
[211]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 1.7 2.7 3.2 4.3 3.2
[212]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 40 33
[213]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 32 50
[214]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 57 78 89
[215]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 23 43
[216]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[217]
liver ACACA
Mean 44
Standard deviation 21
Values 50 70 21 35
[218]
ref_hepatocyte DEPTOR
Mean 2.92
Standard deviation 3
Values 0.49 7.7 4.3 0.98 1.2
[219]
HepG2 DEPTOR
Mean 0.646
Standard deviation 0.42
Values 0.35 0.94
[220]
HepG2.C3A DEPTOR
Mean 1.31
Standard deviation 0.32
Values 1.1 1.5
[221]
HuH.7 DEPTOR
Mean 20.7
Standard deviation 13
Values 12 35 15
[222]
SNU475 DEPTOR
Mean 0.282
Standard deviation 0.12
Values 0.2 0.37
[223]
THLE DEPTOR
Mean 1.97
Standard deviation 0.12
Values 2.1 1.9
[224]
liver DEPTOR
Mean 7.51
Standard deviation 1.7
Values 6.9 7.2 9.9 6
[225]
ref_hepatocyte ATP13A2
Mean 2.65
Standard deviation 2.2
Values 6.2 0.4 1.6 2.6 2.4
[226]
HepG2 ATP13A2
Mean 27.9
Standard deviation 0.28
Values 28 28
[227]
HepG2.C3A ATP13A2
Mean 21.6
Standard deviation 2.1
Values 20 23
[228]
HuH.7 ATP13A2
Mean 3.94
Standard deviation 1.4
Values 3.9 2.6 5.3
[229]
SNU475 ATP13A2
Mean 20.9
Standard deviation 2.6
Values 19 23
[230]
THLE ATP13A2
Mean 16.1
Standard deviation 2.2
Values 15 18
[231]
liver ATP13A2
Mean 3.21
Standard deviation 0.6
Values 4 3.1 2.5 3.2
[232]
ref_hepatocyte ATG14
Mean 2.38
Standard deviation 1.4
Values 2.3 1.4 0.7 3.6 3.9
[233]
HepG2 ATG14
Mean 8.63
Standard deviation 0.18
Values 8.5 8.8
[234]
HepG2.C3A ATG14
Mean 11.3
Standard deviation 0.19
Values 11 11
[235]
HuH.7 ATG14
Mean 11.8
Standard deviation 3.7
Values 9.6 16 9.7
[236]
SNU475 ATG14
Mean 12
Standard deviation 2.7
Values 10 14
[237]
THLE ATG14
Mean 11.5
Standard deviation 0.21
Values 11 12
[238]
liver ATG14
Mean 5.64
Standard deviation 2
Values 7.1 7.5 4.2 3.7
[239]
ref_hepatocyte ATG2A
Mean 2.38
Standard deviation 1.7
Values 2.2 2.8 5 0.79 1.2
[240]
HepG2 ATG2A
Mean 15.2
Standard deviation 2.3
Values 14 17
[241]
HepG2.C3A ATG2A
Mean 15
Standard deviation 8.9
Values 8.7 21
[242]
HuH.7 ATG2A
Mean 17.9
Standard deviation 3.2
Values 14 19 21
[243]
SNU475 ATG2A
Mean 12.6
Standard deviation 1.4
Values 12 14
[244]
THLE ATG2A
Mean 17.4
Standard deviation 3.4
Values 15 20
[245]
liver ATG2A
Mean 23
Standard deviation 4.3
Values 25 28 18 21
[246]
ref_hepatocyte ATG7
Mean 1.98
Standard deviation 0.67
Values 2.5 2.4 2.3 0.88 1.8
[247]
HepG2 ATG7
Mean 8.71
Standard deviation 0.27
Values 8.5 8.9
[248]
HepG2.C3A ATG7
Mean 5.51
Standard deviation 0.43
Values 5.8 5.2
[249]
HuH.7 ATG7
Mean 8.79
Standard deviation 1.8
Values 9.1 6.9 10
[250]
SNU475 ATG7
Mean 5.82
Standard deviation 0.2
Values 6 5.7
[251]
THLE ATG7
Mean 11.8
Standard deviation 1.9
Values 10 13
[252]
liver ATG7
Mean 9.51
Standard deviation 2.7
Values 11 12 6.5 8.1
[253]
ref_hepatocyte RPTOR
Mean 1.96
Standard deviation 0.72
Values 2.6 1.2 1.1 2.5 2.4
[254]
HepG2 RPTOR
Mean 36.8
Standard deviation 1
Values 38 36
[255]
HepG2.C3A RPTOR
Mean 19.3
Standard deviation 0.98
Values 19 20
[256]
HuH.7 RPTOR
Mean 19.8
Standard deviation 7.4
Values 17 14 28
[257]
SNU475 RPTOR
Mean 13
Standard deviation 0.49
Values 13 13
[258]
THLE RPTOR
Mean 17.1
Standard deviation 3.1
Values 15 19
[259]
liver RPTOR
Mean 14.1
Standard deviation 7.6
Values 21 20 7.5 7.6
[260]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.2 3.2 2.4 1.4 1.7
[261]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 12 7.4
[262]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 10 7.8
[263]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 16 14 20
[264]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[265]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[266]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 27 27 15 12
[267]
ref_hepatocyte ATG10
Mean 1.86
Standard deviation 0.78
Values 1.5 1.5 1.9 1.2 3.2
[268]
HepG2 ATG10
Mean 2.85
Standard deviation 0.7
Values 3.3 2.3
[269]
HepG2.C3A ATG10
Mean 3.3
Standard deviation 1.3
Values 4.2 2.4
[270]
HuH.7 ATG10
Mean 3.75
Standard deviation 0.42
Values 4 3.3 4
[271]
SNU475 ATG10
Mean 4.08
Standard deviation 1.2
Values 3.2 4.9
[272]
THLE ATG10
Mean 2.51
Standard deviation 0.4
Values 2.2 2.8
[273]
liver ATG10
Mean 2.98
Standard deviation 1.3
Values 1.9 1.8 4.4 3.8
[274]
ref_hepatocyte TSC1
Mean 1.81
Standard deviation 0.96
Values 2.1 1.1 0.7 3.1 2.1
[275]
HepG2 TSC1
Mean 14.8
Standard deviation 1.6
Values 16 14
[276]
HepG2.C3A TSC1
Mean 20.9
Standard deviation 3.3
Values 19 23
[277]
HuH.7 TSC1
Mean 22.2
Standard deviation 4.3
Values 18 26 22
[278]
SNU475 TSC1
Mean 13.9
Standard deviation 2.8
Values 12 16
[279]
THLE TSC1
Mean 18
Standard deviation 3.2
Values 16 20
[280]
liver TSC1
Mean 17.4
Standard deviation 1.8
Values 17 20 17 16
[281]
ref_hepatocyte DCAF17
Mean 1.79
Standard deviation 1.6
Values 0.8 0.87 0.47 4.4 2.4
[282]
HepG2 DCAF17
Mean 9.43
Standard deviation 2.4
Values 11 7.7
[283]
HepG2.C3A DCAF17
Mean 24.5
Standard deviation 4.1
Values 27 22
[284]
HuH.7 DCAF17
Mean 9.67
Standard deviation 1.9
Values 8.9 8.3 12
[285]
SNU475 DCAF17
Mean 8.71
Standard deviation 0.55
Values 8.3 9.1
[286]
THLE DCAF17
Mean 9.91
Standard deviation 0.58
Values 10 9.5
[287]
liver DCAF17
Mean 5.8
Standard deviation 1.2
Values 5.1 7.6 5 5.4
[288]
ref_hepatocyte PLA2G6
Mean 0.654
Standard deviation 0.59
Values 0.068 1.4 0.69 1 0.078
[289]
HepG2 PLA2G6
Mean 1.5
Standard deviation 0.1
Values 1.4 1.6
[290]
HepG2.C3A PLA2G6
Mean 7.2
Standard deviation 0.86
Values 6.6 7.8
[291]
HuH.7 PLA2G6
Mean 8.73
Standard deviation 1.3
Values 10 8.4 7.6
[292]
SNU475 PLA2G6
Mean 1.08
Standard deviation 0.58
Values 0.67 1.5
[293]
THLE PLA2G6
Mean 1.26
Standard deviation 0.079
Values 1.3 1.2
[294]
liver PLA2G6
Mean 2.91
Standard deviation 0.67
Values 2.4 2.3 3.5 3.4
[295]
ref_hepatocyte FA2H
Mean 0.036
Standard deviation 0.049
Values 0.084 0 0 0 0.096
[296]
HepG2 FA2H
Mean 0.145
Standard deviation 0.078
Values 0.09 0.2
[297]
HepG2.C3A FA2H
Mean 0.103
Standard deviation 0.036
Values 0.13 0.078
[298]
HuH.7 FA2H
Mean 0.0205
Standard deviation 0.023
Values 0.047 0.0064 0.0082
[299]
SNU475 FA2H
Mean 0.0312
Standard deviation 0.0083
Values 0.025 0.037
[300]
THLE FA2H
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[301]
liver FA2H
Mean 0.068
Standard deviation 0.068
Values 0.15 0 0.024 0.1
[302]
ref_hepatocyte ATG101
Missing
[303]
HepG2 ATG101
Missing
[304]
HepG2.C3A ATG101
Missing
[305]
HuH.7 ATG101
Missing
[306]
SNU475 ATG101
Missing
[307]
THLE ATG101
Missing
[308]
liver ATG101
Missing