WP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RHOA | Transforming protein RhoA | [1] | -0.67[2] | -0.94[3] | -0.86[4] | -1.11[5] | -0.67[6] | -1.38[7] |
2 | ARF1 | ADP-ribosylation factor 1 | [8] | -0.92[9] | -0.49[10] | -0.24[11] | -0.49[12] | -0.83[13] | -0.75[14] |
3 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [15] | -0.13[16] | -0.23[17] | 0.34[18] | 0.12[19] | 0.10[20] | -1.02[21] |
4 | JUN | Transcription factor AP-1 | [22] | -0.22[23] | -1.54[24] | -1.41[25] | -1.59[26] | -1.03[27] | -1.86[28] |
5 | FOS | Proto-oncogene c-Fos | [29] | -5.74[30] | -4.25[31] | -5.06[32] | -6.06[33] | -5.00[34] | -1.36[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | 0.35[37] | 0.34[38] | -0.88[39] | 0.06[40] | 0.07[41] | -0.30[42] |
7 | STAT3 | Signal transducer and activator of transcription 3 | [43] | 0.82[44] | -0.45[45] | 0.14[46] | 0.35[47] | -0.38[48] | 2.35[49] |
8 | PAK2 | Serine/threonine-protein kinase PAK 2 | [50] | 1.71[51] | 1.69[52] | 1.84[53] | 0.86[54] | 1.40[55] | 1.31[56] |
9 | AKT2 | RAC-beta serine/threonine-protein kinase | [57] | 1.23[58] | 1.73[59] | 1.72[60] | 0.97[61] | 0.75[62] | 1.08[63] |
10 | EPHB4 | Ephrin type-B receptor 4 | [64] | 2.19[65] | 1.79[66] | 1.91[67] | -0.46[68] | 0.32[69] | 1.63[70] |
11 | PAK4 | Serine/threonine-protein kinase PAK 4 | [71] | 1.16[72] | 1.43[73] | 1.98[74] | 1.13[75] | 0.85[76] | -0.38[77] |
12 | NGEF | Ephexin-1 | [78] | 0.62[79] | 1.74[80] | 1.78[81] | -4.91[82] | -2.31[83] | 0.75[84] |
13 | TRIO | Triple functional domain protein | [85] | 2.27[86] | 2.23[87] | 2.33[88] | 2.72[89] | 3.59[90] | 2.70[91] |
14 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 1.48[92] | 2.22[93] | 2.23[94] | 1.16[95] | 1.31[96] | 1.10[97] | |
15 | KIDINS220 | Kinase D-interacting substrate of 220 kDa | [98] | 1.86[99] | 2.71[100] | 2.18[101] | 3.03[102] | 2.48[103] | 3.21[104] |
16 | SORT1 | Sortilin | [105] | 3.69[106] | 4.34[107] | 2.76[108] | 4.07[109] | 2.69[110] | -0.03[111] |
17 | PAK1 | Serine/threonine-protein kinase PAK 1 | [112] | 0.26[113] | -0.27[114] | 1.99[115] | -1.75[116] | 2.03[117] | 0.21[118] |
18 | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4 | [119] | 1.43[120] | 1.72[121] | 2.54[122] | 1.78[123] | 2.24[124] | 2.82[125] |
19 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.11[126] | 1.75[127] | 1.80[128] | 1.24[129] | 1.43[130] | 1.86[131] | |
20 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.15[132] | 3.47[133] | -0.48[134] | 0.39[135] | 1.15[136] | 0.24[137] | |
21 | MMP9 | Matrix metalloproteinase-9 | [138] | -2.45[139] | -3.27[140] | -5.81[141] | -1.32[142] | -3.89[143] | -0.19[144] |
22 | EPHB2 | Ephrin type-B receptor 2 | [145] | -0.57[146] | -5.40[147] | 0.88[148] | 2.48[149] | 3.21[150] | -1.63[151] |
23 | F2RL2 | Proteinase-activated receptor 3 | [152] | -5.16[153] | -3.98[154] | -2.18[155] | 3.82[156] | -1.25[157] | 0.77[158] |
24 | EPHB6 | Ephrin type-B receptor 6 | [159] | -4.84[160] | [161] | -7.69[162] | -2.58[163] | 0.40[164] | 0.74[165] |
25 | TIAM1 | T-lymphoma invasion and metastasis-inducing protein 1 | [166] | -4.43[167] | -1.53[168] | -6.86[169] | -1.25[170] | 0.79[171] | 3.29[172] |
26 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [173] | 1.99[174] | 2.23[175] | 2.93[176] | 3.28[177] | 2.29[178] | 2.62[179] |
27 | EPHB1 | Ephrin type-B receptor 1 | [180] | 1.05[181] | -4.41[182] | -5.42[183] | [184] | -5.51[185] | 1.71[186] |
28 | AKT3 | RAC-gamma serine/threonine-protein kinase | [187] | -1.57[188] | -3.90[189] | -3.36[190] | 5.95[191] | 4.90[192] | 3.55[193] |
29 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [194] | -6.90[195] | [196] | -2.18[197] | -3.81[198] | -3.48[199] | 2.28[200] |
30 | MMP2 | 72 kDa type IV collagenase | [201] | 3.70[202] | -3.05[203] | -1.92[204] | 7.55[205] | 7.09[206] | 3.88[207] |
31 | PAK3 | Serine/threonine-protein kinase PAK 3 | [208] | -6.14[209] | [210] | [211] | -1.49[212] | 0.22[213] | 0.73[214] |
32 | PAK6 | Serine/threonine-protein kinase PAK 6 | [215] | -1.41[216] | [217] | 1.41[218] | 2.31[219] | 1.42[220] | -1.13[221] |
33 | CDH11 | Cadherin-11 | [222] | -2.08[223] | [224] | -1.65[225] | 1.93[226] | 8.70[227] | 3.33[228] |
34 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [229] | [230] | [231] | 1.45[232] | -3.44[233] | 4.04[234] | |
35 | BDNF | Brain-derived neurotrophic factor | [235] | -1.39[236] | -3.93[237] | -2.15[238] | 6.85[239] | 5.61[240] | 2.04[241] |
36 | EPHB3 | Ephrin type-B receptor 3 | [242] | 0.87[243] | -3.43[244] | 3.71[245] | 3.48[246] | 3.34[247] | 2.95[248] |
37 | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 | [249] | [250] | [251] | -2.21[252] | [253] | [254] | 1.77[255] |
38 | NGFR | Tumor necrosis factor receptor superfamily member 16 | [256] | 8.73[257] | 2.11[258] | -2.03[259] | 1.86[260] | 2.79[261] | 7.55[262] |
39 | MMP8 | Neutrophil collagenase | [263] | [264] | [265] | [266] | [267] | -1.93[268] | 3.00[269] |
40 | PAK5 | Serine/threonine-protein kinase PAK 5 | [270] | [271] | [272] | [273] | [274] | [275] | [276] |
41 | BUB1B-PA | BUB1B-PAK6 readthrough (Fragment) | [277] | [278] | [279] | [280] | [281] | [282] | [283] |
42 | NTRK2 | BDNF/NT-3 growth factors receptor | [284] | [285] | [286] | [287] | [288] | [289] | [290] |
43 | TWIST1 | Twist-related protein 1 | [291] | [292] | [293] | [294] | [295] | [296] | [297] |
44 | MIR3620 | [298] | [299] | [300] | [301] | [302] | [303] | [304] |