WP_NANOPARTICLE_TRIGGERED_REGULATED_NECROSIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FTL Ferritin light chain [1] -0.07[2] -0.09[3] -0.15[4] -0.06[5] -0.28[6] -0.02[7]
2 PARP1 Poly [ADP-ribose] polymerase 1 [8] 2.29[9] 2.44[10] 3.43[11] 1.88[12] 3.51[13] 0.83[14]
3 TNFRSF1A Tumor necrosis factor receptor superfamily member 1A [15] 1.69[16] 1.62[17] 2.18[18] 1.71[19] 4.02[20] 1.32[21]
4 FADD FAS-associated death domain protein [22] 2.20[23] 1.89[24] 2.87[25] 3.28[26] 3.21[27] -0.53[28]
5 CASP8 Caspase-8 [29] 2.18[30] 3.15[31] 2.57[32] 1.27[33] 2.64[34] -0.18[35]
6 MAPK8 Mitogen-activated protein kinase 8 [36] 0.72[37] 2.52[38] 1.65[39] 0.45[40] 2.42[41] 0.73[42]
7 TRADD Tumor necrosis factor receptor type 1-associated DEATH domain protein 1.91[43] 2.14[44] 1.22[45] 0.36[46] 2.33[47] 0.65[48]
8 TICAM1 TIR domain-containing adapter molecule 1 [49] 1.45[50] 0.74[51] 1.93[52] 0.12[53] 3.29[54] 0.74[55]
9 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [56] 2.45[57] 3.01[58] 2.94[59] 2.43[60] 4.07[61] 2.73[62]
10 RIPK3 Receptor-interacting serine/threonine-protein kinase 3 [63] -4.48[64] [65] -2.51[66] [67] -1.91[68] 1.80[69]
11 TNF Tumor necrosis factor [70] 3.26[71] 1.52[72] -2.82[73] -0.87[74] -1.98[75] -0.65[76]
12 PLA2G4A Cytosolic phospholipase A2 [77] 2.43[78] 0.27[79] 8.63[80] 4.85[81] 10.73[82] 5.59[83]
[1]
ref_hepatocyte FTL
Mean 6.65e+03
Standard deviation 4e+03
Values 2.9e+03 1.1e+04 1.1e+04 5.1e+03 3.5e+03
[2]
HepG2 FTL
Mean 3.12e+03
Standard deviation 7.3e+02
Values 2.6e+03 3.6e+03
[3]
HepG2.C3A FTL
Mean 2.09e+03
Standard deviation 7.1e+02
Values 2.6e+03 1.6e+03
[4]
HuH.7 FTL
Mean 1.61e+03
Standard deviation 1.7e+02
Values 1.7e+03 1.4e+03 1.7e+03
[5]
SNU475 FTL
Mean 4.59e+03
Standard deviation 6.3e+02
Values 4.1e+03 5e+03
[6]
THLE FTL
Mean 1.02e+03
Standard deviation 75
Values 9.6e+02 1.1e+03
[7]
liver FTL
Mean 3.93e+03
Standard deviation 4.2e+03
Values 3.1e+02 6.9e+02 5.7e+03 9e+03
[8]
ref_hepatocyte PARP1
Mean 36.6
Standard deviation 31
Values 33 16 17 26 91
[9]
HepG2 PARP1
Mean 88.3
Standard deviation 6.6
Values 93 84
[10]
HepG2.C3A PARP1
Mean 66.3
Standard deviation 14
Values 76 56
[11]
HuH.7 PARP1
Mean 106
Standard deviation 38
Values 1.3e+02 62 1.3e+02
[12]
SNU475 PARP1
Mean 96.8
Standard deviation 5.2
Values 93 1e+02
[13]
THLE PARP1
Mean 77.5
Standard deviation 13
Values 68 87
[14]
liver PARP1
Mean 39.1
Standard deviation 10
Values 31 44 31 51
[15]
ref_hepatocyte TNFRSF1A
Mean 30.7
Standard deviation 20
Values 24 48 55 11 15
[16]
HepG2 TNFRSF1A
Mean 49
Standard deviation 6
Values 45 53
[17]
HepG2.C3A TNFRSF1A
Mean 31.7
Standard deviation 8.2
Values 26 37
[18]
HuH.7 TNFRSF1A
Mean 37.3
Standard deviation 0.38
Values 37 37 38
[19]
SNU475 TNFRSF1A
Mean 72.7
Standard deviation 0.99
Values 72 73
[20]
THLE TNFRSF1A
Mean 92.5
Standard deviation 20
Values 78 1.1e+02
[21]
liver TNFRSF1A
Mean 46.1
Standard deviation 22
Values 33 26 51 74
[22]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 20 5.1 6.3 3.8 12
[23]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 18 24
[24]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 13 10
[25]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 22 16 16
[26]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 58 73
[27]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[28]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 5.1 4.9 2.5 3
[29]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 8.9 2.8 1.9 18 13
[30]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 18 22
[31]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 35 17
[32]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 18 11 14
[33]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 15 16
[34]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[35]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 5 5.2 3.4 5.3
[36]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[37]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[38]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[39]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[40]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[41]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[42]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[43]
ref_hepatocyte TRADD
Mean 5.53
Standard deviation 1.5
Values 5.3 6.5 7.4 3.6 4.8
[44]
HepG2 TRADD
Mean 10.2
Standard deviation 3.2
Values 8 12
[45]
HepG2.C3A TRADD
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[46]
HuH.7 TRADD
Mean 3.47
Standard deviation 1.2
Values 4.9 2.7 2.9
[47]
SNU475 TRADD
Mean 5.13
Standard deviation 1
Values 4.4 5.8
[48]
THLE TRADD
Mean 5.18
Standard deviation 0.33
Values 4.9 5.4
[49]
liver TRADD
Mean 5.22
Standard deviation 3
Values 3 2.7 9.2 6
[50]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 16 3 3.4 0 1.4
[51]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 4.3 8.5
[52]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 2.2 3.1
[53]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 4.9 4.5 5.2
[54]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.9 3.5
[55]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[56]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 2.3 1.4 7.9 7.4
[57]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.1 4.8 5.4 3.7 4.4
[58]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 14 8.7
[59]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 12 11
[60]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.8 9.3 8.4
[61]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 15 19
[62]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[63]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 22 21 12 13
[64]
ref_hepatocyte RIPK3
Mean 0.227
Standard deviation 0.15
Values 0.33 0.29 0.15 0 0.37
[65]
HepG2 RIPK3
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[66]
HepG2.C3A RIPK3
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 RIPK3
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[68]
SNU475 RIPK3
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE RIPK3
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[70]
liver RIPK3
Mean 0.474
Standard deviation 0.21
Values 0.33 0.43 0.78 0.36
[71]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[72]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[73]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[74]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[75]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[76]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[77]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[78]
ref_hepatocyte PLA2G4A
Mean 0.0266
Standard deviation 0.038
Values 0 0.081 0.052 0 0
[79]
HepG2 PLA2G4A
Mean 0.0708
Standard deviation 0.027
Values 0.09 0.052
[80]
HepG2.C3A PLA2G4A
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[81]
HuH.7 PLA2G4A
Mean 2.84
Standard deviation 0.53
Values 3.4 2.6 2.5
[82]
SNU475 PLA2G4A
Mean 0.554
Standard deviation 0.44
Values 0.86 0.25
[83]
THLE PLA2G4A
Mean 8.43
Standard deviation 1.4
Values 9.4 7.5
[84]
liver PLA2G4A
Mean 0.772
Standard deviation 0.24
Values 0.77 1.1 0.56 0.64