WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FN1 | Fibronectin | [1] | 1.30[2] | 1.17[3] | 1.08[4] | 0.92[5] | 0.94[6] | 0.85[7] |
2 | ITGB1 | Integrin beta-1 | [8] | -1.96[9] | -1.54[10] | -1.39[11] | -0.54[12] | -0.64[13] | -1.28[14] |
3 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [15] | -3.12[16] | -3.05[17] | -2.46[18] | -2.54[19] | -2.21[20] | -2.63[21] |
4 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [22] | -2.13[23] | -2.06[24] | -1.18[25] | -2.84[26] | -2.54[27] | -3.14[28] |
5 | GRB2 | Growth factor receptor-bound protein 2 | [29] | -0.99[30] | -0.76[31] | -0.62[32] | -1.45[33] | -1.71[34] | -1.14[35] |
6 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [36] | -2.25[37] | -1.45[38] | -0.17[39] | -2.19[40] | -1.50[41] | -0.34[42] |
7 | NRAS | GTPase NRas | [43] | -1.56[44] | -0.73[45] | -0.30[46] | -1.00[47] | -1.61[48] | -1.69[49] |
8 | TLN1 | Talin-1 | [50] | 0.81[51] | -0.17[52] | 0.62[53] | 1.11[54] | 0.95[55] | 1.92[56] |
9 | HRAS | GTPase HRas | [57] | -3.20[58] | -3.51[59] | -4.28[60] | -2.95[61] | -3.34[62] | -4.10[63] |
10 | MAPK1 | Mitogen-activated protein kinase 1 | [64] | -0.48[65] | 0.05[66] | -0.10[67] | -0.15[68] | -0.68[69] | 0.33[70] |
11 | PXN | Paxillin | [71] | -1.19[72] | -1.07[73] | -1.02[74] | 0.12[75] | -0.10[76] | -1.79[77] |
12 | KRAS | GTPase KRas | [78] | -2.70[79] | -2.33[80] | -0.71[81] | -1.20[82] | -1.72[83] | -0.77[84] |
13 | PTK2 | Focal adhesion kinase 1 | [85] | -1.45[86] | -0.57[87] | -0.17[88] | -0.05[89] | -1.03[90] | -0.68[91] |
14 | MAPK14 | Mitogen-activated protein kinase 14 | [92] | -0.71[93] | -0.25[94] | -0.66[95] | -0.32[96] | -1.02[97] | -0.16[98] |
15 | MAPK8 | Mitogen-activated protein kinase 8 | [99] | -3.63[100] | -1.83[101] | -2.94[102] | -2.90[103] | -3.22[104] | -1.95[105] |
16 | SOS1 | Son of sevenless homolog 1 | [106] | -2.29[107] | -0.36[108] | -0.84[109] | -1.16[110] | -2.10[111] | -0.90[112] |
17 | ITGA1 | Integrin alpha-1 | [113] | -3.03[114] | -1.52[115] | -1.52[116] | -3.02[117] | -1.84[118] | 2.20[119] |
18 | EGFR | Epidermal growth factor receptor | [120] | -2.88[121] | -2.86[122] | 0.03[123] | -1.57[124] | -1.13[125] | 1.21[126] |
19 | MAPK13 | Mitogen-activated protein kinase 13 | [127] | 0.15[128] | 0.95[129] | -1.71[130] | -3.89[131] | -2.55[132] | -3.16[133] |
20 | AREG | Amphiregulin | [134] | -5.05[135] | -7.90[136] | -9.64[137] | -11.70[138] | -1.57[139] | -11.75[140] |
21 | MAPK9 | Mitogen-activated protein kinase 9 | [141] | -0.96[142] | -0.34[143] | -0.26[144] | -0.29[145] | -1.01[146] | -0.93[147] |
22 | SRC | Proto-oncogene tyrosine-protein kinase Src | [148] | 0.84[149] | 1.22[150] | 0.23[151] | 0.40[152] | -0.60[153] | -2.29[154] |
23 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | -0.30[155] | 1.18[156] | -2.62[157] | -1.72[158] | -1.13[159] | -1.14[160] | |
24 | MAPK12 | Mitogen-activated protein kinase 12 | [161] | 0.63[162] | 0.69[163] | 1.82[164] | -0.52[165] | 0.56[166] | -2.35[167] |
25 | COL1A1 | Collagen alpha-1(I) chain | [168] | 2.55[169] | -4.56[170] | -2.73[171] | 5.01[172] | 6.37[173] | 4.91[174] |
26 | AKT3 | RAC-gamma serine/threonine-protein kinase | [175] | -4.03[176] | -6.19[177] | -5.49[178] | 3.84[179] | 2.62[180] | 2.17[181] |
27 | MAPK11 | Mitogen-activated protein kinase 11 | [182] | -2.36[183] | -2.07[184] | -2.94[185] | -1.65[186] | 0.17[187] | -1.28[188] |
28 | MAPK10 | Mitogen-activated protein kinase 10 | [189] | -3.67[190] | [191] | [192] | 6.91[193] | 2.47[194] | 5.81[195] |
29 | MIR6852 | [196] | [197] | [198] | [199] | [200] | [201] | [202] |