WP_NANOMATERIALINDUCED_INFLAMMASOME_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CTSB Cathepsin B [1] 0.05[2] 0.03[3] -0.01[4] -0.07[5] -0.39[6] -0.06[7]
2 NFKB1 Nuclear factor NF-kappa-B p105 subunit [8] 0.19[9] 0.43[10] 1.23[11] 1.10[12] 0.84[13] 0.40[14]
3 CASP1 Caspase-1 [15] -3.51[16] -6.35[17] -3.81[18] 1.43[19] 0.42[20] -0.78[21]
4 IL1B Interleukin-1 beta [22] -9.17[23] -8.48[24] -3.15[25] -2.24[26] 2.18[27] -5.25[28]
5 PYCARD Apoptosis-associated speck-like protein containing a CARD [29] -0.42[30] 0.33[31] -7.72[32] -6.89[33] 0.52[34] -0.89[35]
6 TLR4 Toll-like receptor 4 [36] -0.21[37] -4.80[38] -4.68[39] -3.75[40] 5.50[41] 4.41[42]
7 NOX1 NADPH oxidase 1 [43] -0.12[44] -0.33[45] 5.84[46] 1.29[47] 1.50[48] 0.78[49]
[1]
ref_hepatocyte CTSB
Mean 179
Standard deviation 43
Values 1.1e+02 2.1e+02 1.9e+02 2.2e+02 1.6e+02
[2]
HepG2 CTSB
Mean 571
Standard deviation 1.3e+02
Values 4.8e+02 6.6e+02
[3]
HepG2.C3A CTSB
Mean 341
Standard deviation 1.2e+02
Values 2.5e+02 4.3e+02
[4]
HuH.7 CTSB
Mean 158
Standard deviation 28
Values 1.4e+02 1.9e+02 1.4e+02
[5]
SNU475 CTSB
Mean 123
Standard deviation 9
Values 1.3e+02 1.2e+02
[6]
THLE CTSB
Mean 249
Standard deviation 5.4
Values 2.4e+02 2.5e+02
[7]
liver CTSB
Mean 253
Standard deviation 1.2e+02
Values 1.3e+02 1.7e+02 3e+02 4e+02
[8]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[9]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[10]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[11]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[12]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[13]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[14]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[15]
ref_hepatocyte CASP1
Mean 3.66
Standard deviation 3.7
Values 0.076 4.9 3.7 0.5 9.1
[16]
HepG2 CASP1
Mean 0.987
Standard deviation 0.74
Values 1.5 0.46
[17]
HepG2.C3A CASP1
Mean 0.0833
Standard deviation 0.049
Values 0.12 0.049
[18]
HuH.7 CASP1
Mean 0.231
Standard deviation 0.041
Values 0.23 0.27 0.19
[19]
SNU475 CASP1
Mean 7.12
Standard deviation 0.23
Values 6.9 7.3
[20]
THLE CASP1
Mean 8.87
Standard deviation 1.2
Values 9.7 8
[21]
liver CASP1
Mean 3.13
Standard deviation 0.99
Values 2 2.6 3.7 4.2
[22]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[23]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[24]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[25]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[26]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[27]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[28]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[29]
ref_hepatocyte PYCARD
Mean 2.47
Standard deviation 1.8
Values 2.3 5.2 2.7 0.17 2
[30]
HepG2 PYCARD
Mean 5.68
Standard deviation 3.5
Values 3.2 8.1
[31]
HepG2.C3A PYCARD
Mean 5.76
Standard deviation 0.0033
Values 5.8 5.8
[32]
HuH.7 PYCARD
Mean 0.0103
Standard deviation 0.013
Values 0 0.0064 0.025
[33]
SNU475 PYCARD
Mean 0.015
Standard deviation 0.015
Values 0.025 0.0046
[34]
THLE PYCARD
Mean 6.42
Standard deviation 0.22
Values 6.3 6.6
[35]
liver PYCARD
Mean 1.97
Standard deviation 1.2
Values 0.99 0.9 3.3 2.7
[36]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0.33 0.66 0.64 0 1.1
[37]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 2.1 0.82
[38]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.054 0.019
[39]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0.037 0.019 0
[40]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.035 0.023
[41]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[42]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 25 19 13 11
[43]
ref_hepatocyte NOX1
Mean 0.0251
Standard deviation 0.034
Values 0 0.065 0.06 0 0
[44]
HepG2 NOX1
Mean 0.0708
Standard deviation 0.027
Values 0.09 0.052
[45]
HepG2.C3A NOX1
Mean 0.037
Standard deviation 0.039
Values 0.064 0.0097
[46]
HuH.7 NOX1
Mean 1.27
Standard deviation 0.85
Values 1.8 0.29 1.8
[47]
SNU475 NOX1
Mean 0.0441
Standard deviation 0.016
Values 0.056 0.032
[48]
THLE NOX1
Mean 0.129
Standard deviation 0.069
Values 0.18 0.08
[49]
liver NOX1
Mean 0.0636
Standard deviation 0.1
Values 0 0.043 0.21 0