WP_NAD_BIOSYNTHESIS_II_FROM_TRYPTOPHAN Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TDO2 Tryptophan 2,3-dioxygenase [1] -13.19[2] -11.67[3] -7.17[4] -4.65[5] -6.16[6] 0.88[7]
2 KYNU Kynureninase [8] -1.35[9] -1.20[10] -3.20[11] -1.10[12] -0.94[13] -2.79[14]
3 QPRT Nicotinate-nucleotide pyrophosphorylase [carboxylating] [15] 1.97[16] 1.61[17] 2.27[18] 1.88[19] 1.14[20] -0.69[21]
4 HAAO 3-hydroxyanthranilate 3,4-dioxygenase [22] -1.99[23] -1.35[24] -2.46[25] -7.90[26] -8.90[27] -0.91[28]
5 AFMID Kynurenine formamidase [29] 0.86[30] 1.67[31] 0.88[32] -0.91[33] 0.61[34] 0.24[35]
6 NADSYN1 Glutamine-dependent NAD(+) synthetase [36] 2.65[37] 2.09[38] 1.63[39] 3.11[40] 3.84[41] 0.26[42]
7 KMO Kynurenine 3-monooxygenase [43] -7.41[44] -6.22[45] -3.04[46] -0.17[47] -4.17[48] 1.43[49]
8 NMNAT1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 [50] 1.81[51] 2.94[52] 1.72[53] 3.82[54] 4.27[55] 0.08[56]
[1]
ref_hepatocyte TDO2
Mean 130
Standard deviation 1.9e+02
Values 5.3 4.3e+02 2e+02 0 18
[2]
HepG2 TDO2
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[3]
HepG2.C3A TDO2
Mean 0.037
Standard deviation 0.039
Values 0.064 0.0097
[4]
HuH.7 TDO2
Mean 0.435
Standard deviation 0.39
Values 0.26 0.89 0.16
[5]
SNU475 TDO2
Mean 1.01
Standard deviation 0.68
Values 1.5 0.53
[6]
THLE TDO2
Mean 0.203
Standard deviation 0.19
Values 0.34 0.069
[7]
liver TDO2
Mean 397
Standard deviation 2.8e+02
Values 1.8e+02 1.8e+02 7.8e+02 4.4e+02
[8]
ref_hepatocyte KYNU
Mean 90.5
Standard deviation 1.2e+02
Values 70 24 31 22 3.1e+02
[9]
HepG2 KYNU
Mean 27.4
Standard deviation 17
Values 16 39
[10]
HepG2.C3A KYNU
Mean 36.6
Standard deviation 14
Values 47 26
[11]
HuH.7 KYNU
Mean 4.72
Standard deviation 2.1
Values 3.2 7.1 3.9
[12]
SNU475 KYNU
Mean 8.24
Standard deviation 5.2
Values 12 4.6
[13]
THLE KYNU
Mean 5.29
Standard deviation 2.8
Values 7.2 3.3
[14]
liver KYNU
Mean 21.7
Standard deviation 3.4
Values 21 18 26 22
[15]
ref_hepatocyte QPRT
Mean 54.6
Standard deviation 24
Values 18 83 60 66 46
[16]
HepG2 QPRT
Mean 166
Standard deviation 13
Values 1.8e+02 1.6e+02
[17]
HepG2.C3A QPRT
Mean 155
Standard deviation 28
Values 1.4e+02 1.7e+02
[18]
HuH.7 QPRT
Mean 127
Standard deviation 6.4
Values 1.2e+02 1.3e+02 1.2e+02
[19]
SNU475 QPRT
Mean 39.2
Standard deviation 20
Values 25 54
[20]
THLE QPRT
Mean 13.5
Standard deviation 0.43
Values 13 14
[21]
liver QPRT
Mean 56.2
Standard deviation 29
Values 34 31 92 68
[22]
ref_hepatocyte HAAO
Mean 49.4
Standard deviation 65
Values 9.1 1.5e+02 72 8.2 3.8
[23]
HepG2 HAAO
Mean 9.61
Standard deviation 2.4
Values 11 7.9
[24]
HepG2.C3A HAAO
Mean 18
Standard deviation 2.2
Values 16 20
[25]
HuH.7 HAAO
Mean 4.33
Standard deviation 0.95
Values 4.9 3.2 4.8
[26]
SNU475 HAAO
Mean 0.0405
Standard deviation 0.021
Values 0.025 0.056
[27]
THLE HAAO
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[28]
liver HAAO
Mean 43.7
Standard deviation 25
Values 23 21 64 67
[29]
ref_hepatocyte AFMID
Mean 27.8
Standard deviation 20
Values 4.8 35 51 41 7.6
[30]
HepG2 AFMID
Mean 39
Standard deviation 12
Values 47 31
[31]
HepG2.C3A AFMID
Mean 82.2
Standard deviation 14
Values 72 92
[32]
HuH.7 AFMID
Mean 24.5
Standard deviation 7.7
Values 32 17 25
[33]
SNU475 AFMID
Mean 2.9
Standard deviation 0.18
Values 2.8 3
[34]
THLE AFMID
Mean 4.73
Standard deviation 0.045
Values 4.7 4.8
[35]
liver AFMID
Mean 54.5
Standard deviation 41
Values 28 23 1.1e+02 54
[36]
ref_hepatocyte NADSYN1
Mean 6.84
Standard deviation 2.5
Values 3.2 6.5 9.5 8.9 6.1
[37]
HepG2 NADSYN1
Mean 33.2
Standard deviation 0.013
Values 33 33
[38]
HepG2.C3A NADSYN1
Mean 27
Standard deviation 8
Values 21 33
[39]
HuH.7 NADSYN1
Mean 10.2
Standard deviation 0.43
Values 10 9.8 11
[40]
SNU475 NADSYN1
Mean 11.5
Standard deviation 5
Values 8 15
[41]
THLE NADSYN1
Mean 11
Standard deviation 0.13
Values 11 11
[42]
liver NADSYN1
Mean 13.7
Standard deviation 3.8
Values 10 12 19 14
[43]
ref_hepatocyte KMO
Mean 3.63
Standard deviation 4.2
Values 0.79 8.8 7.5 0.026 0.95
[44]
HepG2 KMO
Mean 0.0165
Standard deviation 0.0071
Values 0.021 0.011
[45]
HepG2.C3A KMO
Mean 0.0452
Standard deviation 0.018
Values 0.032 0.058
[46]
HuH.7 KMO
Mean 0.212
Standard deviation 0.072
Values 0.17 0.3 0.17
[47]
SNU475 KMO
Mean 0.629
Standard deviation 0.51
Values 0.99 0.27
[48]
THLE KMO
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[49]
liver KMO
Mean 16.3
Standard deviation 7.3
Values 9.6 14 27 15
[50]
ref_hepatocyte NMNAT1
Mean 2.87
Standard deviation 1.2
Values 1.6 2 2.6 4.6 3.6
[51]
HepG2 NMNAT1
Mean 7.76
Standard deviation 0.7
Values 8.2 7.3
[52]
HepG2.C3A NMNAT1
Mean 20.4
Standard deviation 2.1
Values 22 19
[53]
HuH.7 NMNAT1
Mean 4.53
Standard deviation 0.81
Values 5.1 3.6 4.9
[54]
SNU475 NMNAT1
Mean 7.88
Standard deviation 1.8
Values 6.6 9.2
[55]
THLE NMNAT1
Mean 6.18
Standard deviation 0.82
Values 5.6 6.8
[56]
liver NMNAT1
Mean 5.02
Standard deviation 0.66
Values 4.2 5.3 4.9 5.8