WP_MYD88_DISTINCT_INPUTOUTPUT_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 JUN Transcription factor AP-1 [1] -0.56[2] -1.82[3] -0.89[4] -1.13[5] -1.22[6] -1.32[7]
2 UBE2V1 Ubiquitin-conjugating enzyme E2 variant 1 [8] -3.95[9] -3.85[10] -3.05[11] -3.31[12] -4.62[13] -4.53[14]
3 IRAK1 Interleukin-1 receptor-associated kinase 1 [15] 1.34[16] 1.02[17] 0.66[18] 1.37[19] 1.08[20] -0.20[21]
4 UBE2N Ubiquitin-conjugating enzyme E2 N [22] 0.62[23] 1.38[24] 0.86[25] 0.89[26] 0.13[27] -0.23[28]
5 MYD88 Myeloid differentiation primary response protein MyD88 [29] -0.26[30] 0.09[31] 0.18[32] -0.46[33] -0.82[34] 1.28[35]
6 NFKB1 Nuclear factor NF-kappa-B p105 subunit [36] 0.60[37] 0.56[38] 1.01[39] 0.33[40] 0.58[41] 0.93[42]
7 TIFA TRAF-interacting protein with FHA domain-containing protein A [43] -0.13[44] 1.27[45] 1.97[46] -0.07[47] 0.88[48] 0.77[49]
8 TLR2 Toll-like receptor 2 [50] -3.62[51] -1.91[52] -8.26[53] -4.39[54] 1.70[55] 1.73[56]
9 TRAF6 TNF receptor-associated factor 6 [57] 1.02[58] 1.19[59] 2.42[60] 2.24[61] 1.03[62] 3.39[63]
10 TLR4 Toll-like receptor 4 [64] 0.20[65] -4.67[66] -4.90[67] -4.52[68] 5.24[69] 4.95[70]
11 TLR1 Toll-like receptor 1 [71] -3.44[72] [73] -6.14[74] 0.18[75] 0.70[76] 2.55[77]
12 TLR10 Toll-like receptor 10 [78] -2.92[79] -0.77[80] -1.11[81] -1.23[82] -2.19[83] -0.48[84]
13 TLR6 Toll-like receptor 6 [85] 0.71[86] 1.11[87] 1.00[88] 2.88[89] 2.30[90] 3.23[91]
14 TLR5 Toll-like receptor 5 [92] -3.36[93] -5.12[94] 1.01[95] -1.41[96] -1.93[97] 3.40[98]
15 TLR7 Toll-like receptor 7 [99] -0.91[100] 0.17[101] 1.13[102] 0.00[103] -1.10[104] 1.76[105]
16 TLR8 Toll-like receptor 8 [106] [107] [108] [109] [110] -6.11[111] 4.14[112]
17 IL1A Interleukin-1 alpha [113] -0.50[114] -0.61[115] -1.13[116] -0.06[117] 6.03[118] -1.10[119]
18 TLR9 Toll-like receptor 9 [120] [121] [122] [123] [124] [125] [126]
19 MIR718 [127] [128] [129] [130] [131] [132] [133]
[1]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 66 20 73 26 30
[2]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 42 93
[3]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 13 28
[4]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 14 46 11
[5]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 27 21
[6]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[7]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 12 24 25 8.4
[8]
ref_hepatocyte UBE2V1
Mean 30.9
Standard deviation 6.6
Values 33 27 29 41 25
[9]
HepG2 UBE2V1
Mean 4.65
Standard deviation 0.14
Values 4.7 4.6
[10]
HepG2.C3A UBE2V1
Mean 3.63
Standard deviation 0.17
Values 3.5 3.8
[11]
HuH.7 UBE2V1
Mean 3.85
Standard deviation 0.39
Values 3.5 3.8 4.3
[12]
SNU475 UBE2V1
Mean 3.83
Standard deviation 0.48
Values 3.5 4.2
[13]
THLE UBE2V1
Mean 2.74
Standard deviation 0.61
Values 2.3 3.2
[14]
liver UBE2V1
Mean 1.36
Standard deviation 0.64
Values 0.78 0.84 1.9 2
[15]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 38 5 16 18 30
[16]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 97 1.5e+02
[17]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 75 72
[18]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 34 31 40
[19]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 78 58
[20]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[21]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 24 19 17 15
[22]
ref_hepatocyte UBE2N
Mean 19.2
Standard deviation 7.8
Values 25 12 11 19 28
[23]
HepG2 UBE2N
Mean 68.4
Standard deviation 19
Values 82 55
[24]
HepG2.C3A UBE2N
Mean 84.8
Standard deviation 36
Values 1.1e+02 60
[25]
HuH.7 UBE2N
Mean 36
Standard deviation 8.3
Values 43 27 38
[26]
SNU475 UBE2N
Mean 44
Standard deviation 3.7
Values 41 47
[27]
THLE UBE2N
Mean 45.7
Standard deviation 8
Values 40 51
[28]
liver UBE2N
Mean 16.6
Standard deviation 11
Values 5.9 8.3 25 27
[29]
ref_hepatocyte MYD88
Mean 12.3
Standard deviation 6.2
Values 14 17 19 5.4 6
[30]
HepG2 MYD88
Mean 23.8
Standard deviation 12
Values 32 16
[31]
HepG2.C3A MYD88
Mean 22.1
Standard deviation 5.1
Values 26 18
[32]
HuH.7 MYD88
Mean 14.3
Standard deviation 1.1
Values 15 13 15
[33]
SNU475 MYD88
Mean 11
Standard deviation 1.1
Values 10 12
[34]
THLE MYD88
Mean 15.1
Standard deviation 1.7
Values 14 16
[35]
liver MYD88
Mean 30.3
Standard deviation 21
Values 14 9.8 47 51
[36]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[37]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[38]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[39]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[40]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[41]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[42]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[43]
ref_hepatocyte TIFA
Mean 2.71
Standard deviation 0.94
Values 2.8 2 4.2 1.8 2.8
[44]
HepG2 TIFA
Mean 5.78
Standard deviation 0.44
Values 5.5 6.1
[45]
HepG2.C3A TIFA
Mean 11.1
Standard deviation 2.4
Values 13 9.3
[46]
HuH.7 TIFA
Mean 11
Standard deviation 1.3
Values 10 12 10
[47]
SNU475 TIFA
Mean 3.18
Standard deviation 0.18
Values 3.3 3.1
[48]
THLE TIFA
Mean 10.9
Standard deviation 0.82
Values 10 11
[49]
liver TIFA
Mean 4.69
Standard deviation 1.3
Values 4 3.2 5.7 5.9
[50]
ref_hepatocyte TLR2
Mean 1.56
Standard deviation 1.2
Values 2.3 1.4 3.1 0 0.96
[51]
HepG2 TLR2
Mean 0.296
Standard deviation 0.084
Values 0.24 0.36
[52]
HepG2.C3A TLR2
Mean 0.704
Standard deviation 0.0056
Values 0.71 0.7
[53]
HuH.7 TLR2
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[54]
SNU475 TLR2
Mean 0.0914
Standard deviation 0.057
Values 0.13 0.051
[55]
THLE TLR2
Mean 11.1
Standard deviation 4.3
Values 14 8.1
[56]
liver TLR2
Mean 5.26
Standard deviation 1.6
Values 5.9 6.8 3.2 5.1
[57]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[58]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[59]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[60]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[61]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[62]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[63]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8
[64]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0.33 0.66 0.64 0 1.1
[65]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 2.1 0.82
[66]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.054 0.019
[67]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0.037 0.019 0
[68]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.035 0.023
[69]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[70]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 25 19 13 11
[71]
ref_hepatocyte TLR1
Mean 0.481
Standard deviation 0.24
Values 0.38 0.7 0.69 0.12 0.52
[72]
HepG2 TLR1
Mean 0.103
Standard deviation 0.024
Values 0.086 0.12
[73]
HepG2.C3A TLR1
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 TLR1
Mean 0.00701
Standard deviation 0.0065
Values 0 0.013 0.0082
[75]
SNU475 TLR1
Mean 0.672
Standard deviation 0.026
Values 0.65 0.69
[76]
THLE TLR1
Mean 1.71
Standard deviation 0.1
Values 1.8 1.6
[77]
liver TLR1
Mean 2.86
Standard deviation 1.1
Values 3 4.4 2 2.1
[78]
ref_hepatocyte TLR10
Mean 0.282
Standard deviation 0.2
Values 0.2 0.24 0.052 0.61 0.31
[79]
HepG2 TLR10
Mean 0.0866
Standard deviation 0.041
Values 0.12 0.057
[80]
HepG2.C3A TLR10
Mean 0.28
Standard deviation 0.0022
Values 0.28 0.28
[81]
HuH.7 TLR10
Mean 0.135
Standard deviation 0.061
Values 0.094 0.21 0.11
[82]
SNU475 TLR10
Mean 0.148
Standard deviation 0.02
Values 0.16 0.13
[83]
THLE TLR10
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[84]
liver TLR10
Mean 0.205
Standard deviation 0.11
Values 0.32 0.29 0.14 0.077
[85]
ref_hepatocyte TLR6
Mean 0.179
Standard deviation 0.1
Values 0.082 0.13 0.12 0.23 0.34
[86]
HepG2 TLR6
Mean 0.681
Standard deviation 0.059
Values 0.64 0.72
[87]
HepG2.C3A TLR6
Mean 0.655
Standard deviation 0.06
Values 0.7 0.61
[88]
HuH.7 TLR6
Mean 0.369
Standard deviation 0.13
Values 0.22 0.42 0.46
[89]
SNU475 TLR6
Mean 1.62
Standard deviation 0.2
Values 1.8 1.5
[90]
THLE TLR6
Mean 1.93
Standard deviation 0.11
Values 2 1.9
[91]
liver TLR6
Mean 1.7
Standard deviation 1
Values 2.5 2.6 0.63 1.1
[92]
ref_hepatocyte TLR5
Mean 0.11
Standard deviation 0.25
Values 0 0 0.55 0 0
[93]
HepG2 TLR5
Mean 0.0251
Standard deviation 0.0051
Values 0.021 0.029
[94]
HepG2.C3A TLR5
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[95]
HuH.7 TLR5
Mean 0.229
Standard deviation 0.085
Values 0.13 0.27 0.29
[96]
SNU475 TLR5
Mean 0.0511
Standard deviation 0.0066
Values 0.056 0.046
[97]
THLE TLR5
Mean 0.0633
Standard deviation 0.031
Values 0.041 0.085
[98]
liver TLR5
Mean 1.19
Standard deviation 0.33
Values 0.86 0.96 1.4 1.5
[99]
ref_hepatocyte TLR7
Mean 0.103
Standard deviation 0.13
Values 0.03 0.13 0.043 0 0.31
[100]
HepG2 TLR7
Mean 0.127
Standard deviation 0.026
Values 0.15 0.11
[101]
HepG2.C3A TLR7
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[102]
HuH.7 TLR7
Mean 0.233
Standard deviation 0.072
Values 0.18 0.31 0.21
[103]
SNU475 TLR7
Mean 0.126
Standard deviation 0.0079
Values 0.13 0.12
[104]
THLE TLR7
Mean 0.105
Standard deviation 0.028
Values 0.12 0.085
[105]
liver TLR7
Mean 0.352
Standard deviation 0.11
Values 0.3 0.49 0.24 0.39
[106]
ref_hepatocyte TLR8
Mean 0.084
Standard deviation 0.14
Values 0 0.33 0.095 0 0
[107]
HepG2 TLR8
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A TLR8
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 TLR8
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 TLR8
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE TLR8
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[112]
liver TLR8
Mean 1.51
Standard deviation 1.1
Values 3 1.7 0.54 0.8
[113]
ref_hepatocyte IL1A
Mean 0.05
Standard deviation 0.11
Values 0.25 0 0 0 0
[114]
HepG2 IL1A
Mean 0.0823
Standard deviation 0.035
Values 0.11 0.057
[115]
HepG2.C3A IL1A
Mean 0.0555
Standard deviation 0.018
Values 0.043 0.068
[116]
HuH.7 IL1A
Mean 0.0235
Standard deviation 0.041
Values 0 0.071 0
[117]
SNU475 IL1A
Mean 0.0589
Standard deviation 0.024
Values 0.076 0.042
[118]
THLE IL1A
Mean 7.11
Standard deviation 1.8
Values 8.4 5.8
[119]
liver IL1A
Mean 0.0237
Standard deviation 0.034
Values 0 0.071 0.024 0
[120]
ref_hepatocyte TLR9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 TLR9
Mean 0.0229
Standard deviation 0.032
Values 0 0.046
[122]
HepG2.C3A TLR9
Mean 0.197
Standard deviation 0.2
Values 0.054 0.34
[123]
HuH.7 TLR9
Mean 1.11
Standard deviation 1.2
Values 0.37 2.5 0.44
[124]
SNU475 TLR9
Mean 0.0454
Standard deviation 0.021
Values 0.03 0.06
[125]
THLE TLR9
Mean 0.22
Standard deviation 0.12
Values 0.3 0.14
[126]
liver TLR9
Mean 0.227
Standard deviation 0.11
Values 0.38 0.23 0.12 0.18
[127]
ref_hepatocyte MIR718
Missing
[128]
HepG2 MIR718
Missing
[129]
HepG2.C3A MIR718
Missing
[130]
HuH.7 MIR718
Missing
[131]
SNU475 MIR718
Missing
[132]
THLE MIR718
Missing
[133]
liver MIR718
Missing