WP_MRNA_PROTEIN_AND_METABOLITE_INDUCATION_PATHWAY_BY_CYCLOSPORIN_A Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ATF4 Cyclic AMP-dependent transcription factor ATF-4 [1] -1.53[2] -0.37[3] -0.24[4] -2.29[5] -1.14[6] -0.58[7]
2 SLC3A2 4F2 cell-surface antigen heavy chain [8] -0.42[9] -1.45[10] -1.08[11] -0.11[12] 0.16[13] -0.42[14]
3 SLC7A5 Large neutral amino acids transporter small subunit 1 [15] 2.52[16] 1.35[17] 0.48[18] 0.62[19] 1.10[20] -0.14[21]
4 NFE2L2 Nuclear factor erythroid 2-related factor 2 [22] 0.40[23] 1.40[24] 1.23[25] 1.20[26] 1.15[27] 1.80[28]
5 KEAP1 Kelch-like ECH-associated protein 1 [29] -0.15[30] -0.19[31] -0.22[32] -0.07[33] 0.62[34] 2.18[35]
6 SLC1A5 Neutral amino acid transporter B(0) [36] 3.25[37] 2.51[38] 2.67[39] 3.93[40] 2.84[41] -0.30[42]
7 SLC7A11 Cystine/glutamate transporter [43] 2.31[44] 3.22[45] 3.29[46] 5.62[47] 4.13[48] 0.61[49]
[1]
ref_hepatocyte ATF4
Mean 212
Standard deviation 1.7e+02
Values 4.8e+02 1.3e+02 2.7e+02 76 1.1e+02
[2]
HepG2 ATF4
Mean 208
Standard deviation 25
Values 1.9e+02 2.3e+02
[3]
HepG2.C3A ATF4
Mean 397
Standard deviation 1.4e+02
Values 3e+02 4.9e+02
[4]
HuH.7 ATF4
Mean 356
Standard deviation 84
Values 4.5e+02 3.1e+02 3.1e+02
[5]
SNU475 ATF4
Mean 47.8
Standard deviation 2.6
Values 46 50
[6]
THLE ATF4
Mean 145
Standard deviation 1.3
Values 1.5e+02 1.4e+02
[7]
liver ATF4
Mean 64.9
Standard deviation 27
Values 46 44 1e+02 68
[8]
ref_hepatocyte SLC3A2
Mean 72.1
Standard deviation 43
Values 1.3e+02 22 1e+02 56 49
[9]
HepG2 SLC3A2
Mean 153
Standard deviation 40
Values 1.2e+02 1.8e+02
[10]
HepG2.C3A SLC3A2
Mean 64.2
Standard deviation 13
Values 55 74
[11]
HuH.7 SLC3A2
Mean 67.5
Standard deviation 3
Values 70 68 64
[12]
SNU475 SLC3A2
Mean 73.5
Standard deviation 36
Values 99 48
[13]
THLE SLC3A2
Mean 122
Standard deviation 3.4
Values 1.2e+02 1.2e+02
[14]
liver SLC3A2
Mean 24.7
Standard deviation 11
Values 16 16 28 39
[15]
ref_hepatocyte SLC7A5
Mean 20.3
Standard deviation 37
Values 8.1 1.8 3.7 86 1.6
[16]
HepG2 SLC7A5
Mean 330
Standard deviation 84
Values 2.7e+02 3.9e+02
[17]
HepG2.C3A SLC7A5
Mean 125
Standard deviation 38
Values 98 1.5e+02
[18]
HuH.7 SLC7A5
Mean 56.1
Standard deviation 23
Values 61 31 76
[19]
SNU475 SLC7A5
Mean 34.2
Standard deviation 11
Values 26 42
[20]
THLE SLC7A5
Mean 65.6
Standard deviation 9.3
Values 72 59
[21]
liver SLC7A5
Mean 8.45
Standard deviation 2.5
Values 7.6 5.7 8.8 12
[22]
ref_hepatocyte NFE2L2
Mean 15.6
Standard deviation 4.9
Values 11 19 21 18 9.4
[23]
HepG2 NFE2L2
Mean 58.6
Standard deviation 25
Values 76 41
[24]
HepG2.C3A NFE2L2
Mean 99.8
Standard deviation 19
Values 1.1e+02 86
[25]
HuH.7 NFE2L2
Mean 72.7
Standard deviation 3
Values 74 75 69
[26]
SNU475 NFE2L2
Mean 39.6
Standard deviation 2.1
Values 41 38
[27]
THLE NFE2L2
Mean 52.3
Standard deviation 3.2
Values 55 50
[28]
liver NFE2L2
Mean 25
Standard deviation 9.2
Values 15 21 28 36
[29]
ref_hepatocyte KEAP1
Mean 14.9
Standard deviation 4.1
Values 17 15 20 11 11
[30]
HepG2 KEAP1
Mean 38
Standard deviation 2.6
Values 36 40
[31]
HepG2.C3A KEAP1
Mean 31.6
Standard deviation 0.82
Values 32 31
[32]
HuH.7 KEAP1
Mean 25.2
Standard deviation 5.2
Values 30 20 26
[33]
SNU475 KEAP1
Mean 15.5
Standard deviation 1.8
Values 17 14
[34]
THLE KEAP1
Mean 34.5
Standard deviation 4.9
Values 31 38
[35]
liver KEAP1
Mean 30.9
Standard deviation 7.7
Values 29 23 31 41
[36]
ref_hepatocyte SLC1A5
Mean 6.14
Standard deviation 9.9
Values 4.1 1.4 0.9 24 0.7
[37]
HepG2 SLC1A5
Mean 166
Standard deviation 92
Values 1e+02 2.3e+02
[38]
HepG2.C3A SLC1A5
Mean 84.9
Standard deviation 42
Values 55 1.1e+02
[39]
HuH.7 SLC1A5
Mean 77.4
Standard deviation 25
Values 88 49 95
[40]
SNU475 SLC1A5
Mean 103
Standard deviation 5.6
Values 1.1e+02 99
[41]
THLE SLC1A5
Mean 66.2
Standard deviation 4.6
Values 63 70
[42]
liver SLC1A5
Mean 2.28
Standard deviation 0.7
Values 3.2 1.7 1.8 2.5
[43]
ref_hepatocyte SLC7A11
Mean 1.16
Standard deviation 1.5
Values 1.1 0.081 0.13 0.84 3.6
[44]
HepG2 SLC7A11
Mean 16.2
Standard deviation 8
Values 11 22
[45]
HepG2.C3A SLC7A11
Mean 26.1
Standard deviation 9.4
Values 19 33
[46]
HuH.7 SLC7A11
Mean 22.5
Standard deviation 3.7
Values 18 24 25
[47]
SNU475 SLC7A11
Mean 62.6
Standard deviation 14
Values 72 53
[48]
THLE SLC7A11
Mean 30.6
Standard deviation 10
Values 38 24
[49]
liver SLC7A11
Mean 0.81
Standard deviation 0.61
Values 0.54 0.77 1.7 0.26