WP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [1] | -0.09[2] | -0.73[3] | 0.25[4] | 0.09[5] | 0.33[6] | -1.21[7] |
2 | ARPC1B | Actin-related protein 2/3 complex subunit 1B | [8] | 0.29[9] | -0.32[10] | -1.04[11] | 1.02[12] | 0.31[13] | -1.23[14] |
3 | C1QB | Complement C1q subcomponent subunit B | [15] | [16] | [17] | [18] | [19] | [20] | -0.06[21] |
4 | C1QA | Complement C1q subcomponent subunit A | [22] | [23] | [24] | [25] | -14.07[26] | [27] | -0.43[28] |
5 | C1QC | Complement C1q subcomponent subunit C | [29] | [30] | [31] | [32] | [33] | [34] | -0.22[35] |
6 | CYBA | Cytochrome b-245 light chain | [36] | 1.79[37] | 1.52[38] | 0.69[39] | 0.29[40] | 0.44[41] | -1.66[42] |
7 | TYROBP | TYRO protein tyrosine kinase-binding protein | [43] | -9.65[44] | [45] | [46] | -8.98[47] | [48] | -1.91[49] |
8 | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma | [50] | -4.77[51] | -4.19[52] | -6.89[53] | -8.38[54] | -6.10[55] | -1.21[56] |
9 | NCF2 | Neutrophil cytosol factor 2 | [57] | -1.51[58] | -4.52[59] | -8.01[60] | -2.81[61] | -9.17[62] | -2.66[63] |
10 | VAV2 | Guanine nucleotide exchange factor VAV2 | [64] | 1.60[65] | 1.54[66] | 1.31[67] | -0.46[68] | 0.22[69] | 0.26[70] |
11 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [71] | -0.17[72] | -0.36[73] | 1.00[74] | 2.14[75] | 1.90[76] | 2.75[77] |
12 | LYN | Tyrosine-protein kinase Lyn | [78] | -0.56[79] | -1.05[80] | -0.24[81] | 1.13[82] | 0.15[83] | -0.23[84] |
13 | PTPN6 | Tyrosine-protein phosphatase non-receptor type 6 | [85] | -0.16[86] | -0.28[87] | 0.57[88] | -7.06[89] | -1.79[90] | -0.43[91] |
14 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [92] | 2.18[93] | 2.09[94] | 2.97[95] | 0.78[96] | 1.60[97] | -0.54[98] |
15 | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | [99] | 0.69[100] | 1.00[101] | 0.36[102] | 0.88[103] | 1.35[104] | 0.38[105] |
16 | RAC2 | Ras-related C3 botulinum toxin substrate 2 | [106] | -1.41[107] | -7.71[108] | -8.05[109] | -1.31[110] | 2.75[111] | -1.48[112] |
17 | ITGB2 | Integrin beta-2 | [113] | 1.60[114] | 2.67[115] | -5.34[116] | -5.11[117] | -6.84[118] | 1.07[119] |
18 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 1.51[120] | 1.71[121] | 2.14[122] | 1.13[123] | 1.54[124] | 0.91[125] | |
19 | RAC3 | Ras-related C3 botulinum toxin substrate 3 | [126] | -0.06[127] | 2.68[128] | 1.79[129] | 0.18[130] | -1.04[131] | -3.72[132] |
20 | PIK3C2A | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | 1.97[133] | 3.23[134] | 3.65[135] | 3.13[136] | 2.68[137] | 3.41[138] | |
21 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.08[139] | 1.25[140] | 1.71[141] | 1.21[142] | 1.67[143] | 1.67[144] | |
22 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.19[145] | 2.97[146] | -0.57[147] | 0.36[148] | 1.38[149] | 0.05[150] | |
23 | NCF1 | Neutrophil cytosol factor 1 | [151] | -6.86[152] | -9.23[153] | [154] | [155] | -8.96[156] | -3.05[157] |
24 | HCK | Tyrosine-protein kinase HCK | [158] | -5.54[159] | -6.03[160] | [161] | -5.19[162] | -5.87[163] | 0.46[164] |
25 | CYBB | Cytochrome b-245 heavy chain | [165] | [166] | [167] | -9.95[168] | -4.40[169] | -9.69[170] | 2.80[171] |
26 | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | -0.98[172] | -7.03[173] | 0.68[174] | -2.66[175] | -1.25[176] | 2.47[177] | |
27 | NCF4 | Neutrophil cytosol factor 4 | [178] | -5.46[179] | -8.09[180] | [181] | -7.98[182] | [183] | 0.66[184] |
28 | LAT | Linker for activation of T-cells family member 1 | [185] | -1.15[186] | 0.08[187] | -1.24[188] | -1.29[189] | -0.45[190] | -0.67[191] |
29 | VAV3 | Guanine nucleotide exchange factor VAV3 | [192] | 2.11[193] | 0.09[194] | 2.54[195] | 3.76[196] | -1.96[197] | 1.10[198] |
30 | SIGLEC7 | Sialic acid-binding Ig-like lectin 7 | [199] | -2.28[200] | [201] | -8.29[202] | -4.61[203] | [204] | 0.86[205] |
31 | NCKAP1L | Nck-associated protein 1-like | [206] | [207] | [208] | [209] | -3.92[210] | -5.13[211] | 2.84[212] |
32 | VAV1 | Proto-oncogene vav | [213] | -8.19[214] | -3.68[215] | -5.12[216] | -6.01[217] | -7.02[218] | 0.93[219] |
33 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [220] | 2.02[221] | 1.72[222] | 2.84[223] | 3.24[224] | 2.52[225] | 2.43[226] |
34 | ITGAM | Integrin alpha-M | [227] | -2.09[228] | -4.95[229] | -3.47[230] | -2.51[231] | -4.68[232] | 2.66[233] |
35 | FCGR1A | High affinity immunoglobulin gamma Fc receptor I | [234] | [235] | [236] | [237] | -6.84[238] | [239] | -0.77[240] |
36 | SYK | Tyrosine-protein kinase SYK | [241] | -7.86[242] | -2.30[243] | -5.05[244] | 0.18[245] | -3.08[246] | 3.11[247] |
37 | TREM2 | Triggering receptor expressed on myeloid cells 2 | [248] | 2.18[249] | -1.82[250] | [251] | -5.71[252] | -2.19[253] | -0.55[254] |
38 | TREM1 | Triggering receptor expressed on myeloid cells 1 | [255] | 1.81[256] | -2.75[257] | [258] | -0.64[259] | 3.63[260] | 0.65[261] |
39 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [262] | [263] | [264] | 1.42[265] | -3.21[266] | 3.85[267] | |
40 | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 | [268] | [269] | [270] | -2.30[271] | [272] | [273] | 1.58[274] |