WP_MEVALONATE_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FDPS Farnesyl pyrophosphate synthase [1] -0.36[2] -1.02[3] -1.19[4] 0.00[5] -0.03[6] -0.96[7]
2 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic [8] -1.19[9] -0.25[10] 0.68[11] -1.34[12] -1.49[13] 0.39[14]
3 ACAT2 Acetyl-CoA acetyltransferase, cytosolic [15] 0.46[16] 0.20[17] -0.75[18] -0.66[19] -0.04[20] -0.09[21]
4 PMVK Phosphomevalonate kinase [22] 0.07[23] -2.14[24] -1.38[25] 0.89[26] 0.74[27] -1.53[28]
5 MVD Diphosphomevalonate decarboxylase [29] 1.36[30] 1.55[31] 0.28[32] 0.54[33] 0.66[34] 0.20[35]
6 HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase [36] 2.05[37] 2.52[38] 2.32[39] 2.63[40] 2.42[41] 2.01[42]
7 MVK Mevalonate kinase [43] 0.30[44] 0.37[45] -0.64[46] -0.28[47] -0.40[48] 0.88[49]
[1]
ref_hepatocyte FDPS
Mean 168
Standard deviation 1.2e+02
Values 65 1.3e+02 1e+02 1.8e+02 3.6e+02
[2]
HepG2 FDPS
Mean 47.3
Standard deviation 9.8
Values 54 40
[3]
HepG2.C3A FDPS
Mean 130
Standard deviation 36
Values 1e+02 1.5e+02
[4]
HuH.7 FDPS
Mean 153
Standard deviation 26
Values 1.8e+02 1.3e+02 1.4e+02
[5]
SNU475 FDPS
Mean 40
Standard deviation 13
Values 31 49
[6]
THLE FDPS
Mean 41.3
Standard deviation 7.5
Values 36 47
[7]
liver FDPS
Mean 78.7
Standard deviation 39
Values 50 54 76 1.3e+02
[8]
ref_hepatocyte HMGCS1
Mean 128
Standard deviation 1e+02
Values 58 72 32 2.5e+02 2.3e+02
[9]
HepG2 HMGCS1
Mean 20.3
Standard deviation 12
Values 28 12
[10]
HepG2.C3A HMGCS1
Mean 170
Standard deviation 81
Values 1.1e+02 2.3e+02
[11]
HuH.7 HMGCS1
Mean 427
Standard deviation 1.7e+02
Values 3.3e+02 6.2e+02 3.3e+02
[12]
SNU475 HMGCS1
Mean 12.1
Standard deviation 4.1
Values 9.2 15
[13]
THLE HMGCS1
Mean 11.4
Standard deviation 0.78
Values 11 12
[14]
liver HMGCS1
Mean 154
Standard deviation 63
Values 2.2e+02 1.9e+02 79 1.3e+02
[15]
ref_hepatocyte ACAT2
Mean 68.2
Standard deviation 50
Values 17 76 49 1.5e+02 51
[16]
HepG2 ACAT2
Mean 33.9
Standard deviation 23
Values 50 18
[17]
HepG2.C3A ACAT2
Mean 123
Standard deviation 6.4
Values 1.2e+02 1.3e+02
[18]
HuH.7 ACAT2
Mean 84.1
Standard deviation 10
Values 95 76 82
[19]
SNU475 ACAT2
Mean 10.3
Standard deviation 0.34
Values 10 11
[20]
THLE ACAT2
Mean 16.6
Standard deviation 3.1
Values 14 19
[21]
liver ACAT2
Mean 58.5
Standard deviation 28
Values 39 47 48 1e+02
[22]
ref_hepatocyte PMVK
Mean 22.4
Standard deviation 12
Values 20 34 33 3.4 22
[23]
HepG2 PMVK
Mean 8.49
Standard deviation 1
Values 7.8 9.2
[24]
HepG2.C3A PMVK
Mean 7.97
Standard deviation 0.74
Values 7.4 8.5
[25]
HuH.7 PMVK
Mean 17.9
Standard deviation 3.9
Values 22 14 18
[26]
SNU475 PMVK
Mean 9.92
Standard deviation 2.1
Values 8.5 11
[27]
THLE PMVK
Mean 9.34
Standard deviation 1.8
Values 8 11
[28]
liver PMVK
Mean 7.06
Standard deviation 5.2
Values 3.4 2.4 13 9
[29]
ref_hepatocyte MVD
Mean 20.1
Standard deviation 9.1
Values 15 24 17 34 10
[30]
HepG2 MVD
Mean 18.7
Standard deviation 5.5
Values 23 15
[31]
HepG2.C3A MVD
Mean 92.8
Standard deviation 59
Values 51 1.3e+02
[32]
HuH.7 MVD
Mean 50.8
Standard deviation 5.1
Values 56 45 51
[33]
SNU475 MVD
Mean 7
Standard deviation 2.5
Values 5.2 8.8
[34]
THLE MVD
Mean 7.96
Standard deviation 0.012
Values 8 8
[35]
liver MVD
Mean 21.1
Standard deviation 12
Values 19 14 12 39
[36]
ref_hepatocyte HMGCR
Mean 14.8
Standard deviation 13
Values 9.1 9.8 5.9 37 12
[37]
HepG2 HMGCR
Mean 22.2
Standard deviation 14
Values 32 12
[38]
HepG2.C3A HMGCR
Mean 133
Standard deviation 31
Values 1.1e+02 1.5e+02
[39]
HuH.7 HMGCR
Mean 154
Standard deviation 61
Values 1.1e+02 2.2e+02 1.3e+02
[40]
SNU475 HMGCR
Mean 22
Standard deviation 2.5
Values 20 24
[41]
THLE HMGCR
Mean 19.8
Standard deviation 3.5
Values 17 22
[42]
liver HMGCR
Mean 54.5
Standard deviation 28
Values 81 71 20 46
[43]
ref_hepatocyte MVK
Mean 14.5
Standard deviation 7.2
Values 7.9 24 20 12 8.7
[44]
HepG2 MVK
Mean 6.45
Standard deviation 1.7
Values 7.6 5.3
[45]
HepG2.C3A MVK
Mean 29.6
Standard deviation 8.4
Values 24 36
[46]
HuH.7 MVK
Mean 19.4
Standard deviation 2
Values 22 18 19
[47]
SNU475 MVK
Mean 2.86
Standard deviation 0.47
Values 2.5 3.2
[48]
THLE MVK
Mean 2.76
Standard deviation 0.64
Values 2.3 3.2
[49]
liver MVK
Mean 24.4
Standard deviation 13
Values 16 11 36 35