WP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RPL11 | 60S ribosomal protein L11 | [1] | [2] | [3] | [4] | [5] | [6] | [7] |
2 | CDC42 | Cell division control protein 42 homolog | [8] | 0.24[9] | 0.99[10] | -0.06[11] | 0.43[12] | -0.22[13] | -1.01[14] |
3 | RAP1B | Ras-related protein Rap-1b | [15] | -1.24[16] | -0.59[17] | -0.86[18] | 0.44[19] | 0.27[20] | -0.82[21] |
4 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [22] | 0.67[23] | 0.38[24] | 1.04[25] | 0.97[26] | 1.03[27] | 0.11[28] |
5 | JUN | Transcription factor AP-1 | [29] | 0.58[30] | -0.93[31] | -0.71[32] | -0.74[33] | -0.10[34] | -0.73[35] |
6 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [36] | 1.91[37] | 0.55[38] | -2.19[39] | -1.03[40] | 1.60[41] | -0.76[42] |
7 | AKT1 | RAC-alpha serine/threonine-protein kinase | [43] | 1.15[44] | 0.95[45] | -0.18[46] | 0.91[47] | 1.01[48] | 0.83[49] |
8 | STAT3 | Signal transducer and activator of transcription 3 | [50] | 1.62[51] | 0.15[52] | 0.84[53] | 1.20[54] | 0.55[55] | 3.48[56] |
9 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [57] | 0.14[58] | -0.16[59] | 0.38[60] | 0.42[61] | 1.00[62] | -0.12[63] |
10 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [64] | 1.12[65] | 0.83[66] | 1.65[67] | 0.12[68] | 0.68[69] | -0.63[70] |
11 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [71] | 1.51[72] | 1.97[73] | 1.89[74] | 1.85[75] | 2.56[76] | 2.33[77] |
12 | GRB2 | Growth factor receptor-bound protein 2 | [78] | 2.26[79] | 2.13[80] | 2.21[81] | 1.51[82] | 1.50[83] | 1.37[84] |
13 | CRK | Adapter molecule crk | [85] | 0.87[86] | 0.83[87] | 0.85[88] | 0.72[89] | 1.19[90] | 1.92[91] |
14 | RAP1A | Ras-related protein Rap-1A | [92] | 0.02[93] | -0.01[94] | 0.78[95] | 0.74[96] | 0.58[97] | -0.22[98] |
15 | BAD | Bcl2-associated agonist of cell death | [99] | -0.60[100] | -0.44[101] | -1.43[102] | -0.11[103] | 0.37[104] | -0.35[105] |
16 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [106] | 1.01[107] | 1.44[108] | 2.66[109] | 0.77[110] | 1.71[111] | 2.17[112] |
17 | NRAS | GTPase NRas | [113] | 1.70[114] | 2.16[115] | 2.53[116] | 1.96[117] | 1.60[118] | 0.82[119] |
18 | MET | Hepatocyte growth factor receptor | [120] | 1.15[121] | 1.21[122] | 1.80[123] | 2.49[124] | 1.29[125] | 2.04[126] |
19 | ARAF | Serine/threonine-protein kinase A-Raf | [127] | 0.61[128] | 0.34[129] | 0.56[130] | 0.86[131] | 0.97[132] | 1.95[133] |
20 | PRCC | Proline-rich protein PRCC | [134] | 1.04[135] | 0.64[136] | 0.94[137] | 1.54[138] | 1.15[139] | 0.15[140] |
21 | HRAS | GTPase HRas | [141] | 0.06[142] | -0.62[143] | -1.45[144] | 0.01[145] | -0.13[146] | -1.59[147] |
22 | ETS1 | Protein C-ets-1 | [148] | -1.73[149] | -11.05[150] | -8.30[151] | 0.87[152] | 1.79[153] | 0.99[154] |
23 | PAK2 | Serine/threonine-protein kinase PAK 2 | [155] | 2.51[156] | 2.29[157] | 2.54[158] | 1.71[159] | 2.33[160] | 2.44[161] |
24 | MAPK1 | Mitogen-activated protein kinase 1 | [162] | 2.78[163] | 2.95[164] | 2.73[165] | 2.81[166] | 2.53[167] | 2.85[168] |
25 | AKT2 | RAC-beta serine/threonine-protein kinase | [169] | 2.03[170] | 2.33[171] | 2.42[172] | 1.82[173] | 1.68[174] | 2.20[175] |
26 | TFE3 | Transcription factor E3 | [176] | 1.73[177] | 1.10[178] | 1.56[179] | 2.39[180] | 1.43[181] | 0.98[182] |
27 | KRAS | GTPase KRas | [183] | 0.55[184] | 0.56[185] | 2.12[186] | 1.76[187] | 1.50[188] | 1.75[189] |
28 | PTK2 | Focal adhesion kinase 1 | [190] | 1.80[191] | 2.32[192] | 2.66[193] | 2.91[194] | 2.18[195] | 1.83[196] |
29 | CRKL | Crk-like protein | [197] | 2.77[198] | 2.90[199] | 3.46[200] | 2.08[201] | 2.36[202] | 2.53[203] |
30 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [204] | 0.60[205] | 0.74[206] | 1.79[207] | 3.03[208] | 2.60[209] | 4.08[210] |
31 | MAPK8 | Mitogen-activated protein kinase 8 | [211] | -0.38[212] | 1.06[213] | -0.11[214] | 0.06[215] | -0.01[216] | 0.56[217] |
32 | SOS1 | Son of sevenless homolog 1 | [218] | 0.97[219] | 2.53[220] | 1.99[221] | 1.80[222] | 1.11[223] | 1.61[224] |
33 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [225] | 2.94[226] | 3.19[227] | 3.76[228] | 1.67[229] | 2.30[230] | 0.78[231] |
34 | RAPGEF1 | Rap guanine nucleotide exchange factor 1 | [232] | 3.16[233] | 3.02[234] | 2.69[235] | 2.22[236] | 1.96[237] | 2.25[238] |
35 | PAK4 | Serine/threonine-protein kinase PAK 4 | [239] | 1.96[240] | 2.03[241] | 2.68[242] | 1.98[243] | 1.78[244] | 0.74[245] |
36 | MAPK3 | Mitogen-activated protein kinase 3 | [246] | 2.92[247] | 2.99[248] | 2.99[249] | 1.38[250] | 1.48[251] | 0.03[252] |
37 | SRC | Proto-oncogene tyrosine-protein kinase Src | [253] | 4.09[254] | 4.11[255] | 3.06[256] | 3.36[257] | 2.61[258] | 0.22[259] |
38 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 4.56[260] | 4.21[261] | 3.49[262] | 3.78[263] | 3.35[264] | 1.41[265] | |
39 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.28[266] | 2.82[267] | 2.93[268] | 2.01[269] | 2.24[270] | 2.23[271] | |
40 | SOS2 | Son of sevenless homolog 2 | [272] | 1.04[273] | 2.20[274] | 1.38[275] | 2.65[276] | 2.59[277] | 2.91[278] |
41 | PAK1 | Serine/threonine-protein kinase PAK 1 | [279] | 1.06[280] | 0.33[281] | 2.69[282] | -0.90[283] | 2.96[284] | 1.34[285] |
42 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 0.69[286] | 2.36[287] | 2.50[288] | 2.09[289] | 2.37[290] | 2.99[291] | |
43 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.96[292] | 4.07[293] | 0.21[294] | 1.24[295] | 2.08[296] | 1.37[297] | |
44 | STRN | Striatin | [298] | 3.04[299] | 4.03[300] | 3.61[301] | 4.28[302] | 4.25[303] | 3.97[304] |
45 | BRAF | Serine/threonine-protein kinase B-raf | [305] | 1.32[306] | 1.07[307] | 3.06[308] | 1.70[309] | 1.47[310] | 2.93[311] |
46 | GAB1 | GRB2-associated-binding protein 1 | [312] | 2.37[313] | 3.49[314] | 3.57[315] | 2.89[316] | 2.83[317] | 3.95[318] |
47 | CBL | E3 ubiquitin-protein ligase CBL | [319] | 5.52[320] | 4.49[321] | 4.67[322] | 6.09[323] | 5.65[324] | 4.83[325] |
48 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [326] | 2.79[327] | 2.83[328] | 3.63[329] | 4.13[330] | 3.22[331] | 3.75[332] |
49 | AKT3 | RAC-gamma serine/threonine-protein kinase | [333] | -0.77[334] | -3.30[335] | -2.66[336] | 6.80[337] | 5.83[338] | 4.68[339] |
50 | JAK3 | Tyrosine-protein kinase JAK3 | [340] | 3.31[341] | 5.62[342] | -0.44[343] | 0.33[344] | 1.13[345] | 4.17[346] |
51 | PAK3 | Serine/threonine-protein kinase PAK 3 | [347] | -5.34[348] | [349] | [350] | -0.64[351] | 1.15[352] | 1.86[353] |
52 | PAK6 | Serine/threonine-protein kinase PAK 6 | [354] | -0.61[355] | [356] | 2.11[357] | 3.16[358] | 2.35[359] | 0.00[360] |
53 | HGF | Hepatocyte growth factor | [361] | [362] | [363] | -0.60[364] | 5.55[365] | 2.66[366] | 9.97[367] |
54 | C8orf34 | Uncharacterized protein C8orf34 | [368] | [369] | [370] | [371] | 3.60[372] | 3.89[373] | 1.47[374] |
55 | PAK5 | Serine/threonine-protein kinase PAK 5 | [375] | [376] | [377] | [378] | [379] | [380] | [381] |
56 | BUB1B-PA | BUB1B-PAK6 readthrough (Fragment) | [382] | [383] | [384] | [385] | [386] | [387] | [388] |
57 | ELOA | Elongin-A | [389] | [390] | [391] | [392] | [393] | [394] | [395] |
58 | INSL3 | Insulin-like 3 | [396] | [397] | [398] | [399] | [400] | [401] | [402] |
59 | ALK | ALK tyrosine kinase receptor | [403] | [404] | [405] | [406] | [407] | [408] | [409] |