WP_METHIONINE_METABOLISM_LEADING_TO_SULFUR_AMINO_ACIDS_AND_RELATED_DISORDERS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MAT1A S-adenosylmethionine synthase isoform type-1 [1] -1.94[2] -0.70[3] -2.67[4] -7.50[5] -9.89[6] 0.67[7]
2 BHMT Betaine--homocysteine S-methyltransferase 1 [8] -4.61[9] -5.42[10] -9.34[11] -6.59[12] -13.25[13] -1.08[14]
3 GNMT Glycine N-methyltransferase [15] -5.85[16] -5.04[17] -9.98[18] -6.37[19] -9.10[20] -1.45[21]
4 AHCY Adenosylhomocysteinase [22] 2.56[23] 2.34[24] 2.53[25] 2.17[26] 1.86[27] -1.28[28]
5 CDO1 Cysteine dioxygenase type 1 [29] -4.68[30] -6.87[31] -4.95[32] -5.38[33] -10.55[34] -0.40[35]
6 CBS Cystathionine beta-synthase [36] 0.08[37] -0.34[38] 1.18[39] -0.68[40] 0.95[41] 0.69[42]
7 ADK Adenosine kinase [43] 0.78[44] 1.15[45] -0.39[46] 0.91[47] 1.44[48] 0.04[49]
8 CTH Cystathionine gamma-lyase [50] -0.85[51] -2.24[52] -0.40[53] -1.66[54] -1.03[55] -0.33[56]
9 MAT2B Methionine adenosyltransferase 2 subunit beta [57] 1.49[58] 0.93[59] 1.08[60] 3.41[61] 3.42[62] -0.25[63]
10 CSAD Cysteine sulfinic acid decarboxylase [64] -1.13[65] 0.01[66] -0.89[67] 1.08[68] 0.84[69] 0.37[70]
11 MTR Methionine synthase [71] 3.84[72] 3.88[73] 3.99[74] 6.09[75] 5.55[76] 3.09[77]
[1]
ref_hepatocyte MAT1A
Mean 212
Standard deviation 2.8e+02
Values 7.2 6.3e+02 3.6e+02 46 12
[2]
HepG2 MAT1A
Mean 41.1
Standard deviation 3.9
Values 44 38
[3]
HepG2.C3A MAT1A
Mean 135
Standard deviation 10
Values 1.3e+02 1.4e+02
[4]
HuH.7 MAT1A
Mean 34.1
Standard deviation 22
Values 22 60 20
[5]
SNU475 MAT1A
Mean 0.281
Standard deviation 0.061
Values 0.24 0.32
[6]
THLE MAT1A
Mean 0.055
Standard deviation 0.048
Values 0.089 0.021
[7]
liver MAT1A
Mean 578
Standard deviation 1.7e+02
Values 4.1e+02 6.1e+02 4.8e+02 8.1e+02
[8]
ref_hepatocyte BHMT
Mean 117
Standard deviation 1.9e+02
Values 6.9 4.5e+02 1.1e+02 8.1 4.9
[9]
HepG2 BHMT
Mean 3.57
Standard deviation 0.19
Values 3.4 3.7
[10]
HepG2.C3A BHMT
Mean 2.82
Standard deviation 2.3
Values 4.4 1.2
[11]
HuH.7 BHMT
Mean 0.184
Standard deviation 0.018
Values 0.2 0.19 0.16
[12]
SNU475 BHMT
Mean 0.29
Standard deviation 0.11
Values 0.21 0.37
[13]
THLE BHMT
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[14]
liver BHMT
Mean 94.8
Standard deviation 50
Values 39 69 1.5e+02 1.2e+02
[15]
ref_hepatocyte GNMT
Mean 73.6
Standard deviation 1.2e+02
Values 3.7 2.8e+02 81 2.1 0.55
[16]
HepG2 GNMT
Mean 0.952
Standard deviation 0.94
Values 1.6 0.29
[17]
HepG2.C3A GNMT
Mean 2.32
Standard deviation 0.99
Values 1.6 3
[18]
HuH.7 GNMT
Mean 0.0743
Standard deviation 0.035
Values 0.11 0.045 0.066
[19]
SNU475 GNMT
Mean 0.213
Standard deviation 0.079
Values 0.16 0.27
[20]
THLE GNMT
Mean 0.0331
Standard deviation 0.013
Values 0.024 0.043
[21]
liver GNMT
Mean 46
Standard deviation 29
Values 25 18 77 65
[22]
ref_hepatocyte AHCY
Mean 72
Standard deviation 24
Values 38 67 80 1e+02 71
[23]
HepG2 AHCY
Mean 316
Standard deviation 75
Values 2.6e+02 3.7e+02
[24]
HepG2.C3A AHCY
Mean 377
Standard deviation 69
Values 3.3e+02 4.3e+02
[25]
HuH.7 AHCY
Mean 425
Standard deviation 39
Values 4e+02 4e+02 4.7e+02
[26]
SNU475 AHCY
Mean 77.3
Standard deviation 9.8
Values 70 84
[27]
THLE AHCY
Mean 64.2
Standard deviation 8.6
Values 58 70
[28]
liver AHCY
Mean 50.8
Standard deviation 11
Values 40 45 55 64
[29]
ref_hepatocyte CDO1
Mean 64.7
Standard deviation 88
Values 1.9 1.9e+02 1.2e+02 1.9 6.3
[30]
HepG2 CDO1
Mean 1.88
Standard deviation 1.5
Values 2.9 0.83
[31]
HepG2.C3A CDO1
Mean 0.569
Standard deviation 0.38
Values 0.84 0.3
[32]
HuH.7 CDO1
Mean 2.14
Standard deviation 0.25
Values 2 2.4 2
[33]
SNU475 CDO1
Mean 0.371
Standard deviation 0.24
Values 0.54 0.2
[34]
THLE CDO1
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[35]
liver CDO1
Mean 83.9
Standard deviation 21
Values 62 76 87 1.1e+02
[36]
ref_hepatocyte CBS
Mean 54.1
Standard deviation 52
Values 21 1.2e+02 96 7.7 22
[37]
HepG2 CBS
Mean 42.6
Standard deviation 25
Values 25 60
[38]
HepG2.C3A CBS
Mean 44
Standard deviation 22
Values 28 60
[39]
HuH.7 CBS
Mean 125
Standard deviation 32
Values 1.5e+02 89 1.4e+02
[40]
SNU475 CBS
Mean 8.06
Standard deviation 1.8
Values 6.8 9.3
[41]
THLE CBS
Mean 25.8
Standard deviation 4.2
Values 29 23
[42]
liver CBS
Mean 150
Standard deviation 40
Values 1.3e+02 1.1e+02 2e+02 1.6e+02
[43]
ref_hepatocyte ADK
Mean 28
Standard deviation 12
Values 13 43 31 32 21
[44]
HepG2 ADK
Mean 35.9
Standard deviation 10
Values 43 29
[45]
HepG2.C3A ADK
Mean 64.3
Standard deviation 18
Values 77 52
[46]
HuH.7 ADK
Mean 21.8
Standard deviation 2.8
Values 25 19 21
[47]
SNU475 ADK
Mean 12.6
Standard deviation 1.1
Values 12 13
[48]
THLE ADK
Mean 18.7
Standard deviation 2.1
Values 17 20
[49]
liver ADK
Mean 49.4
Standard deviation 27
Values 29 26 83 60
[50]
ref_hepatocyte CTH
Mean 20.3
Standard deviation 26
Values 9.9 64 24 1.2 1.6
[51]
HepG2 CTH
Mean 8.35
Standard deviation 5.8
Values 4.2 12
[52]
HepG2.C3A CTH
Mean 4.42
Standard deviation 2.6
Values 2.6 6.3
[53]
HuH.7 CTH
Mean 15.7
Standard deviation 1.2
Values 14 17 16
[54]
SNU475 CTH
Mean 1.54
Standard deviation 0.042
Values 1.6 1.5
[55]
THLE CTH
Mean 2.44
Standard deviation 0.065
Values 2.5 2.4
[56]
liver CTH
Mean 27.6
Standard deviation 15
Values 13 17 38 43
[57]
ref_hepatocyte MAT2B
Mean 12.1
Standard deviation 5.7
Values 6.8 21 9.4 13 9.7
[58]
HepG2 MAT2B
Mean 25.3
Standard deviation 2.8
Values 27 23
[59]
HepG2.C3A MAT2B
Mean 23.8
Standard deviation 7.6
Values 29 18
[60]
HuH.7 MAT2B
Mean 26.2
Standard deviation 6.2
Values 32 20 27
[61]
SNU475 MAT2B
Mean 30.8
Standard deviation 4.2
Values 28 34
[62]
THLE MAT2B
Mean 32
Standard deviation 4.5
Values 29 35
[63]
liver MAT2B
Mean 17.5
Standard deviation 7.4
Values 10 12 22 26
[64]
ref_hepatocyte CSAD
Mean 7.55
Standard deviation 9.6
Values 0.95 22 12 1.3 0.97
[65]
HepG2 CSAD
Mean 2.57
Standard deviation 0.32
Values 2.8 2.3
[66]
HepG2.C3A CSAD
Mean 7.82
Standard deviation 2
Values 6.4 9.2
[67]
HuH.7 CSAD
Mean 4.16
Standard deviation 1.3
Values 5.5 3.9 3
[68]
SNU475 CSAD
Mean 3.82
Standard deviation 1.3
Values 2.9 4.7
[69]
THLE CSAD
Mean 3.32
Standard deviation 0.99
Values 4 2.6
[70]
liver CSAD
Mean 16.7
Standard deviation 6.4
Values 9.5 14 20 24
[71]
ref_hepatocyte MTR
Mean 1.43
Standard deviation 1
Values 1.2 0.48 0.53 2.9 2.1
[72]
HepG2 MTR
Mean 15.2
Standard deviation 4.2
Values 18 12
[73]
HepG2.C3A MTR
Mean 21.8
Standard deviation 0.68
Values 21 22
[74]
HuH.7 MTR
Mean 23.2
Standard deviation 4.8
Values 20 21 29
[75]
SNU475 MTR
Mean 23.4
Standard deviation 7.7
Values 18 29
[76]
THLE MTR
Mean 16.5
Standard deviation 1
Values 17 16
[77]
liver MTR
Mean 20.9
Standard deviation 9.9
Values 24 34 12 14