WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_INCLUDING_DISEASES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA2 Apolipoprotein A-II [1] -1.00[2] -0.83[3] -1.12[4] -8.24[5] -7.46[6] -1.46[7]
2 APOA1 Apolipoprotein A-I [8] -0.98[9] -0.58[10] -2.48[11] -8.75[12] -8.36[13] -0.48[14]
3 APOE Apolipoprotein E [15] -0.40[16] -0.91[17] -0.19[18] -5.47[19] -4.16[20] -1.17[21]
4 ANXA2 Annexin A2 [22] 0.11[23] -0.72[24] 1.27[25] 5.37[26] 5.26[27] -2.85[28]
5 APOB Apolipoprotein B-100 [29] 5.20[30] 5.08[31] 5.00[32] -2.13[33] -1.53[34] 5.54[35]
6 SCARB1 Scavenger receptor class B member 1 [36] 4.22[37] 2.96[38] 3.38[39] 4.39[40] 3.75[41] 1.27[42]
7 LCAT Phosphatidylcholine-sterol acyltransferase [43] -0.77[44] 0.49[45] -2.27[46] -1.25[47] 0.90[48] 0.18[49]
8 LIPC Hepatic triacylglycerol lipase [50] 1.07[51] 0.31[52] 3.04[53] -4.08[54] -4.09[55] 0.35[56]
9 MTTP Microsomal triglyceride transfer protein large subunit [57] 1.12[58] 3.52[59] 5.23[60] -2.07[61] -0.64[62] 2.51[63]
10 LDLR Low-density lipoprotein receptor [64] 3.45[65] 3.40[66] 5.15[67] 4.41[68] 6.15[69] 1.90[70]
11 PCSK9 Proprotein convertase subtilisin/kexin type 9 [71] 0.31[72] 4.51[73] 6.59[74] -0.68[75] -0.55[76] 1.93[77]
12 LIPG Endothelial lipase [78] -2.59[79] -3.41[80] 1.65[81] 0.73[82] -0.23[83] 2.90[84]
13 ABCA1 ATP-binding cassette sub-family A member 1 [85] 4.92[86] 4.95[87] 5.46[88] 6.53[89] 7.63[90] 5.88[91]
14 LDLRAP1 Low density lipoprotein receptor adapter protein 1 [92] 3.06[93] 2.62[94] 2.41[95] 5.83[96] 6.39[97] 1.45[98]
15 CETP Cholesteryl ester transfer protein [99] 2.34[100] 2.07[101] -5.62[102] 5.41[103] 0.04[104] 0.47[105]
16 LPL Lipoprotein lipase [106] [107] [108] -4.30[109] 5.88[110] 2.78[111] 0.43[112]
17 MIR6886 [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte APOA2
Mean 7.33e+03
Standard deviation 9.4e+03
Values 1.6e+03 2e+04 1.5e+04 2.3e+02 92
[2]
HepG2 APOA2
Mean 848
Standard deviation 2.9e+02
Values 1.1e+03 6.5e+02
[3]
HepG2.C3A APOA2
Mean 1.56e+03
Standard deviation 1.1e+02
Values 1.5e+03 1.6e+03
[4]
HuH.7 APOA2
Mean 738
Standard deviation 1.6e+02
Values 9.2e+02 6.4e+02 6.5e+02
[5]
SNU475 APOA2
Mean 1.12
Standard deviation 0.32
Values 1.4 0.9
[6]
THLE APOA2
Mean 1.48
Standard deviation 0.8
Values 2 0.91
[7]
liver APOA2
Mean 2.39e+03
Standard deviation 2.6e+03
Values 1.8e+02 2.2e+02 5.4e+03 3.7e+03
[8]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 9e+02 1.5e+04 7.3e+03 4.7e+03 1.6e+02
[9]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 7.2e+02 5.7e+02
[10]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.1e+03 1.7e+03
[11]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 2.3e+02 2.4e+02 1.8e+02
[12]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[13]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[14]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 7.4e+02 8.6e+02 6.9e+03 5.7e+03
[15]
ref_hepatocyte APOE
Mean 2.9e+03
Standard deviation 3.4e+03
Values 6.9e+02 8.4e+03 3.7e+03 1.5e+03 1.5e+02
[16]
HepG2 APOE
Mean 509
Standard deviation 94
Values 4.4e+02 5.8e+02
[17]
HepG2.C3A APOE
Mean 586
Standard deviation 2.5e+02
Values 4.1e+02 7.7e+02
[18]
HuH.7 APOE
Mean 555
Standard deviation 1.2e+02
Values 5.9e+02 6.6e+02 4.2e+02
[19]
SNU475 APOE
Mean 3.04
Standard deviation 1.2
Values 3.9 2.2
[20]
THLE APOE
Mean 5.77
Standard deviation 1.1
Values 6.5 5
[21]
liver APOE
Mean 1.15e+03
Standard deviation 6.4e+02
Values 6.9e+02 7.6e+02 2.1e+03 1.1e+03
[22]
ref_hepatocyte ANXA2
Mean 343
Standard deviation 4.5e+02
Values 5.3e+02 35 65 40 1e+03
[23]
HepG2 ANXA2
Mean 85.8
Standard deviation 34
Values 62 1.1e+02
[24]
HepG2.C3A ANXA2
Mean 79.3
Standard deviation 3.5
Values 82 77
[25]
HuH.7 ANXA2
Mean 181
Standard deviation 17
Values 2e+02 1.8e+02 1.6e+02
[26]
SNU475 ANXA2
Mean 659
Standard deviation 3.4e+02
Values 4.2e+02 9e+02
[27]
THLE ANXA2
Mean 467
Standard deviation 1.3e+02
Values 3.7e+02 5.6e+02
[28]
liver ANXA2
Mean 42.5
Standard deviation 25
Values 18 38 37 77
[29]
ref_hepatocyte APOB
Mean 165
Standard deviation 1.5e+02
Values 8.3 3.4e+02 2.2e+02 2.4e+02 15
[30]
HepG2 APOB
Mean 1.41e+03
Standard deviation 6.5e+02
Values 1.9e+03 9.5e+02
[31]
HepG2.C3A APOB
Mean 2.13e+03
Standard deviation 5.8e+02
Values 2.5e+03 1.7e+03
[32]
HuH.7 APOB
Mean 1.16e+03
Standard deviation 4.8e+02
Values 6.1e+02 1.5e+03 1.4e+03
[33]
SNU475 APOB
Mean 1.75
Standard deviation 0.12
Values 1.8 1.7
[34]
THLE APOB
Mean 2.04
Standard deviation 0.96
Values 2.7 1.4
[35]
liver APOB
Mean 6.85e+03
Standard deviation 4.5e+03
Values 8.5e+03 1.2e+04 2.9e+03 3.6e+03
[36]
ref_hepatocyte SCARB1
Mean 44.8
Standard deviation 36
Values 20 62 1e+02 25 16
[37]
HepG2 SCARB1
Mean 192
Standard deviation 55
Values 1.5e+02 2.3e+02
[38]
HepG2.C3A SCARB1
Mean 132
Standard deviation 31
Values 1.1e+02 1.5e+02
[39]
HuH.7 SCARB1
Mean 102
Standard deviation 6.8
Values 1e+02 1.1e+02 96
[40]
SNU475 SCARB1
Mean 43.3
Standard deviation 12
Values 35 52
[41]
THLE SCARB1
Mean 21.5
Standard deviation 3.1
Values 19 24
[42]
liver SCARB1
Mean 96.6
Standard deviation 43
Values 61 61 1.2e+02 1.4e+02
[43]
ref_hepatocyte LCAT
Mean 41.5
Standard deviation 53
Values 9.2 1.2e+02 72 6 0.26
[44]
HepG2 LCAT
Mean 5.64
Standard deviation 1.4
Values 6.6 4.7
[45]
HepG2.C3A LCAT
Mean 22.1
Standard deviation 4.3
Values 19 25
[46]
HuH.7 LCAT
Mean 1.88
Standard deviation 0.21
Values 1.8 2.1 1.7
[47]
SNU475 LCAT
Mean 0.81
Standard deviation 0.048
Values 0.78 0.84
[48]
THLE LCAT
Mean 2.75
Standard deviation 1.3
Values 3.7 1.8
[49]
liver LCAT
Mean 42
Standard deviation 38
Values 18 8.9 94 46
[50]
ref_hepatocyte LIPC
Mean 37.4
Standard deviation 43
Values 4 1.1e+02 52 16 9.2
[51]
HepG2 LIPC
Mean 18.2
Standard deviation 4
Values 21 15
[52]
HepG2.C3A LIPC
Mean 17.6
Standard deviation 9.2
Values 11 24
[53]
HuH.7 LIPC
Mean 67.2
Standard deviation 17
Values 61 86 55
[54]
SNU475 LIPC
Mean 0.103
Standard deviation 0.027
Values 0.12 0.083
[55]
THLE LIPC
Mean 0.0784
Standard deviation 0.002
Values 0.077 0.08
[56]
liver LIPC
Mean 42.7
Standard deviation 5.7
Values 36 44 40 50
[57]
ref_hepatocyte MTTP
Mean 24.5
Standard deviation 20
Values 0.63 44 29 43 6.3
[58]
HepG2 MTTP
Mean 12.3
Standard deviation 2.3
Values 14 11
[59]
HepG2.C3A MTTP
Mean 106
Standard deviation 10
Values 1.1e+02 99
[60]
HuH.7 MTTP
Mean 201
Standard deviation 24
Values 1.8e+02 2.3e+02 1.9e+02
[61]
SNU475 MTTP
Mean 0.27
Standard deviation 0.034
Values 0.29 0.25
[62]
THLE MTTP
Mean 0.56
Standard deviation 0.15
Values 0.67 0.45
[63]
liver MTTP
Mean 125
Standard deviation 22
Values 1.5e+02 1.3e+02 1.3e+02 95
[64]
ref_hepatocyte LDLR
Mean 13.7
Standard deviation 8.6
Values 27 4.3 16 7.7 14
[65]
HepG2 LDLR
Mean 34.6
Standard deviation 16
Values 23 46
[66]
HepG2.C3A LDLR
Mean 55.1
Standard deviation 38
Values 29 82
[67]
HuH.7 LDLR
Mean 106
Standard deviation 31
Values 78 1.4e+02 1e+02
[68]
SNU475 LDLR
Mean 13.5
Standard deviation 6.6
Values 8.9 18
[69]
THLE LDLR
Mean 34.7
Standard deviation 13
Values 25 44
[70]
liver LDLR
Mean 45.8
Standard deviation 27
Values 84 24 45 30
[71]
ref_hepatocyte PCSK9
Mean 9.97
Standard deviation 5.7
Values 9.8 15 16 5.6 3.3
[72]
HepG2 PCSK9
Mean 2.85
Standard deviation 1.6
Values 4 1.7
[73]
HepG2.C3A PCSK9
Mean 86.2
Standard deviation 65
Values 40 1.3e+02
[74]
HuH.7 PCSK9
Mean 210
Standard deviation 31
Values 2e+02 2.4e+02 1.8e+02
[75]
SNU475 PCSK9
Mean 0.289
Standard deviation 0.022
Values 0.3 0.27
[76]
THLE PCSK9
Mean 0.242
Standard deviation 0.1
Values 0.31 0.17
[77]
liver PCSK9
Mean 34
Standard deviation 15
Values 52 39 18 27
[78]
ref_hepatocyte LIPG
Mean 9.84
Standard deviation 7.5
Values 12 21 9.7 0.71 5.7
[79]
HepG2 LIPG
Mean 0.376
Standard deviation 0.059
Values 0.33 0.42
[80]
HepG2.C3A LIPG
Mean 0.352
Standard deviation 0.15
Values 0.46 0.24
[81]
HuH.7 LIPG
Mean 6.73
Standard deviation 0.76
Values 7 5.9 7.3
[82]
SNU475 LIPG
Mean 0.753
Standard deviation 0.53
Values 1.1 0.38
[83]
THLE LIPG
Mean 0.298
Standard deviation 0.2
Values 0.16 0.44
[84]
liver LIPG
Mean 65.4
Standard deviation 29
Values 1e+02 72 41 45
[85]
ref_hepatocyte ABCA1
Mean 4.97
Standard deviation 4
Values 0.95 10 5.2 7.4 1.1
[86]
HepG2 ABCA1
Mean 34.8
Standard deviation 18
Values 48 22
[87]
HepG2.C3A ABCA1
Mean 58.2
Standard deviation 2.3
Values 60 57
[88]
HuH.7 ABCA1
Mean 47.7
Standard deviation 23
Values 26 73 44
[89]
SNU475 ABCA1
Mean 21.2
Standard deviation 3.5
Values 24 19
[90]
THLE ABCA1
Mean 35.1
Standard deviation 5.6
Values 39 31
[91]
liver ABCA1
Mean 262
Standard deviation 1.4e+02
Values 4.4e+02 2.8e+02 2.1e+02 1.2e+02
[92]
ref_hepatocyte LDLRAP1
Mean 4.65
Standard deviation 2.5
Values 3.9 5.7 8.1 1.3 4.3
[93]
HepG2 LDLRAP1
Mean 8.97
Standard deviation 0.22
Values 9.1 8.8
[94]
HepG2.C3A LDLRAP1
Mean 10.9
Standard deviation 0.36
Values 11 11
[95]
HuH.7 LDLRAP1
Mean 5.41
Standard deviation 0.72
Values 5.5 4.6 6.1
[96]
SNU475 LDLRAP1
Mean 12.3
Standard deviation 0.53
Values 13 12
[97]
THLE LDLRAP1
Mean 13.9
Standard deviation 0.87
Values 13 15
[98]
liver LDLRAP1
Mean 11.4
Standard deviation 4.1
Values 10 6.2 15 14
[99]
ref_hepatocyte CETP
Mean 1.89
Standard deviation 2.7
Values 0 6.1 3.2 0.14 0
[100]
HepG2 CETP
Mean 2.21
Standard deviation 1.2
Values 1.4 3.1
[101]
HepG2.C3A CETP
Mean 3.02
Standard deviation 1.9
Values 1.7 4.4
[102]
HuH.7 CETP
Mean 0.00839
Standard deviation 0.0095
Values 0.019 0.0064 0
[103]
SNU475 CETP
Mean 3.72
Standard deviation 1.8
Values 5 2.4
[104]
THLE CETP
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[105]
liver CETP
Mean 2.35
Standard deviation 1.5
Values 0.85 1.4 2.9 4.2
[106]
ref_hepatocyte LPL
Mean 0.193
Standard deviation 0.37
Values 0.86 0 0.043 0 0.065
[107]
HepG2 LPL
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A LPL
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 LPL
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[110]
SNU475 LPL
Mean 0.525
Standard deviation 0.3
Values 0.74 0.31
[111]
THLE LPL
Mean 0.0473
Standard deviation 0.0083
Values 0.041 0.053
[112]
liver LPL
Mean 0.233
Standard deviation 0.16
Values 0.44 0.057 0.28 0.15
[113]
ref_hepatocyte MIR6886
Missing
[114]
HepG2 MIR6886
Missing
[115]
HepG2.C3A MIR6886
Missing
[116]
HuH.7 MIR6886
Missing
[117]
SNU475 MIR6886
Missing
[118]
THLE MIR6886
Missing
[119]
liver MIR6886
Missing