WP_MELATONIN_METABOLISM_AND_EFFECTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOE Apolipoprotein E [1] -1.13[2] -1.07[3] -0.79[4] -7.55[5] -7.17[6] -0.52[7]
2 CALM2 Calmodulin-2 [8] 1.02[9] 1.57[10] 0.39[11] 1.48[12] 1.39[13] -0.40[14]
3 SULT1A1 Sulfotransferase 1A1 [15] 1.02[16] 1.35[17] -1.83[18] -0.37[19] -0.69[20] -0.84[21]
4 CYP1A2 Cytochrome P450 1A2 [22] -8.39[23] -7.41[24] -7.77[25] -6.85[26] -7.66[27] -0.34[28]
5 CYP1A1 Cytochrome P450 1A1 [29] -1.94[30] -3.84[31] 0.12[32] -2.26[33] -3.19[34] -4.48[35]
6 CYP2D6 Cytochrome P450 2D6 [36] -5.37[37] -3.21[38] -5.45[39] -6.35[40] -7.26[41] 2.53[42]
7 CALM1 Calmodulin-1 [43] 2.61[44] 2.32[45] 3.08[46] 4.81[47] 3.70[48] 2.93[49]
8 MAOA Amine oxidase [flavin-containing] A [50] -0.67[51] -0.20[52] 2.35[53] -1.42[54] 3.38[55] 2.81[56]
9 IRAK1 Interleukin-1 receptor-associated kinase 1 [57] 3.94[58] 3.02[59] 2.30[60] 4.02[61] 4.01[62] 0.63[63]
10 CYP2C19 Cytochrome P450 2C19 [64] [65] [66] -4.41[67] -10.66[68] -10.86[69] 2.89[70]
11 CSNK1D Casein kinase I isoform delta [71] 3.70[72] 3.15[73] 3.36[74] 4.25[75] 3.40[76] 0.72[77]
12 ECE1 Endothelin-converting enzyme 1 [78] 4.29[79] 3.73[80] 3.78[81] 3.73[82] 4.83[83] 2.97[84]
13 NFKB1 Nuclear factor NF-kappa-B p105 subunit [85] 3.20[86] 2.56[87] 2.64[88] 2.98[89] 3.50[90] 1.76[91]
14 CSNK1E Casein kinase I isoform epsilon [92] 3.89[93] 3.21[94] 4.16[95] 3.70[96] 4.38[97] 0.49[98]
15 ARNTL Aryl hydrocarbon receptor nuclear translocator-like protein 1 [99] 0.45[100] 0.64[101] -0.02[102] 2.18[103] 1.98[104] 2.10[105]
16 CRY1 Cryptochrome-1 [106] 2.24[107] 2.62[108] 2.82[109] 3.57[110] 2.80[111] 1.37[112]
17 CRY2 Cryptochrome-2 [113] 2.61[114] 2.33[115] 4.20[116] 1.25[117] 1.65[118] 3.73[119]
18 PER1 Period circadian protein homolog 1 [120] 0.89[121] 1.38[122] 3.23[123] 1.70[124] 4.56[125] 3.18[126]
19 GSK3B Glycogen synthase kinase-3 beta [127] 3.79[128] 3.11[129] 3.98[130] 5.04[131] 4.48[132] 2.47[133]
20 EDN1 Endothelin-1 [134] 1.75[135] -2.11[136] 2.32[137] 2.75[138] -1.13[139] -0.73[140]
21 CYP1B1 Cytochrome P450 1B1 [141] -4.52[142] -4.27[143] 0.13[144] 4.73[145] 6.95[146] 2.33[147]
22 PRKCA Protein kinase C alpha type [148] 5.36[149] 5.09[150] 5.74[151] 5.38[152] 5.35[153] 3.23[154]
23 SIRT1 NAD-dependent protein deacetylase sirtuin-1 [155] 3.03[156] 3.81[157] 3.66[158] 4.79[159] 4.65[160] 2.65[161]
24 MAP2 Microtubule-associated protein 2 [162] -1.96[163] -4.90[164] -0.82[165] 6.26[166] 5.49[167] 1.97[168]
25 CLOCK Circadian locomoter output cycles protein kaput [169] 3.31[170] 4.20[171] 4.25[172] 5.57[173] 5.80[174] 4.74[175]
26 FOXO1 Forkhead box protein O1 [176] 4.22[177] 3.57[178] 4.00[179] 4.40[180] 6.03[181] 4.40[182]
27 ACHE Acetylcholinesterase [183] 0.44[184] -2.20[185] 1.12[186] -1.93[187] -1.69[188] -3.14[189]
28 PER3 Period circadian protein homolog 3 [190] 2.12[191] 2.17[192] 1.15[193] 5.51[194] 2.01[195] 4.31[196]
29 TRAF6 TNF receptor-associated factor 6 [197] 3.62[198] 3.19[199] 4.05[200] 4.89[201] 3.96[202] 4.22[203]
30 PER2 Period circadian protein homolog 2 [204] 4.23[205] 4.07[206] 5.74[207] 3.61[208] 2.86[209] 3.78[210]
31 ASMT Acetylserotonin O-methyltransferase [211] [212] [213] [214] [215] [216] [217]
32 ADRB1 Beta-1 adrenergic receptor [218] -1.54[219] [220] 4.81[221] 3.76[222] 0.34[223] 3.48[224]
33 AANAT Serotonin N-acetyltransferase [225] 1.88[226] 4.10[227] 4.44[228] 4.60[229] 3.71[230] 2.45[231]
34 MTNR1A Melatonin receptor type 1A [232] [233] [234] [235] [236] [237] [238]
35 MIR126 [239] [240] [241] [242] [243] [244] [245]
36 MIR3142HG [246] [247] [248] [249] [250] [251] [252]
37 MIR146A [253] [254] [255] [256] [257] [258] [259]
38 MTNR1B Melatonin receptor type 1B [260] [261] [262] [263] [264] [265] [266]
39 MIR718 [267] [268] [269] [270] [271] [272] [273]
40 CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha [274] [275] [276] [277] [278] [279] [280]
41 TPTEP2-CSNK1E [281] [282] [283] [284] [285] [286] [287]
42 MIR6883 [288] [289] [290] [291] [292] [293] [294]
[1]
ref_hepatocyte APOE
Mean 2.9e+03
Standard deviation 3.4e+03
Values 6.9e+02 8.4e+03 3.7e+03 1.5e+03 1.5e+02
[2]
HepG2 APOE
Mean 509
Standard deviation 94
Values 4.4e+02 5.8e+02
[3]
HepG2.C3A APOE
Mean 586
Standard deviation 2.5e+02
Values 4.1e+02 7.7e+02
[4]
HuH.7 APOE
Mean 555
Standard deviation 1.2e+02
Values 5.9e+02 6.6e+02 4.2e+02
[5]
SNU475 APOE
Mean 3.04
Standard deviation 1.2
Values 3.9 2.2
[6]
THLE APOE
Mean 5.77
Standard deviation 1.1
Values 6.5 5
[7]
liver APOE
Mean 1.15e+03
Standard deviation 6.4e+02
Values 6.9e+02 7.6e+02 2.1e+03 1.1e+03
[8]
ref_hepatocyte CALM2
Mean 339
Standard deviation 3.5e+02
Values 1e+02 1.7e+02 1.5e+02 3.2e+02 9.5e+02
[9]
HepG2 CALM2
Mean 263
Standard deviation 67
Values 3.1e+02 2.2e+02
[10]
HepG2.C3A CALM2
Mean 427
Standard deviation 1.7e+02
Values 5.5e+02 3.1e+02
[11]
HuH.7 CALM2
Mean 147
Standard deviation 58
Values 2e+02 84 1.6e+02
[12]
SNU475 CALM2
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[13]
THLE CALM2
Mean 254
Standard deviation 11
Values 2.5e+02 2.6e+02
[14]
liver CALM2
Mean 146
Standard deviation 1.1e+02
Values 46 64 2.5e+02 2.3e+02
[15]
ref_hepatocyte SULT1A1
Mean 97.6
Standard deviation 1.2e+02
Values 6 3e+02 1.2e+02 27 33
[16]
HepG2 SULT1A1
Mean 76.1
Standard deviation 9
Values 70 82
[17]
HepG2.C3A SULT1A1
Mean 105
Standard deviation 7.6
Values 1e+02 1.1e+02
[18]
HuH.7 SULT1A1
Mean 9.1
Standard deviation 2.4
Values 12 6.8 8.9
[19]
SNU475 SULT1A1
Mean 14.8
Standard deviation 8.6
Values 8.8 21
[20]
THLE SULT1A1
Mean 17.4
Standard deviation 0.098
Values 17 17
[21]
liver SULT1A1
Mean 31.2
Standard deviation 17
Values 17 16 44 47
[22]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[23]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[24]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[25]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[26]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[27]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[28]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[29]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 0.06 82 17 77 43
[30]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 2.6 6.2
[31]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.2 1.4
[32]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 17 17 14
[33]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 3.1 0.49
[34]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[35]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.8 0.47 1.2 0.92
[36]
ref_hepatocyte CYP2D6
Mean 41.3
Standard deviation 55
Values 3.7 87 1.1e+02 0.24 0.47
[37]
HepG2 CYP2D6
Mean 0.382
Standard deviation 0.03
Values 0.4 0.36
[38]
HepG2.C3A CYP2D6
Mean 1.89
Standard deviation 1
Values 1.2 2.6
[39]
HuH.7 CYP2D6
Mean 0.314
Standard deviation 0.087
Values 0.31 0.4 0.23
[40]
SNU475 CYP2D6
Mean 0.0992
Standard deviation 0.004
Values 0.096 0.1
[41]
THLE CYP2D6
Mean 0.0775
Standard deviation 0.049
Values 0.11 0.043
[42]
liver CYP2D6
Mean 137
Standard deviation 1.2e+02
Values 57 53 3.1e+02 1.3e+02
[43]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 21 40 28 17 40
[44]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 71 65
[45]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 73 51
[46]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 92 64 90
[47]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.4e+02 1.8e+02
[48]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[49]
liver CALM1
Mean 127
Standard deviation 70
Values 57 80 2.1e+02 1.7e+02
[50]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 8.6 41 34 3.4 23
[51]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.2 5.5
[52]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 6.5 9.8
[53]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 28 49 36
[54]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 2.1 1.1
[55]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[56]
liver MAOA
Mean 88.9
Standard deviation 19
Values 65 90 1.1e+02 88
[57]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 38 5 16 18 30
[58]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 97 1.5e+02
[59]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 75 72
[60]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 34 31 40
[61]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 78 58
[62]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[63]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 24 19 17 15
[64]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 72 18 0 5.9
[65]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.2 0.6 0.098
[68]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[69]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[70]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 38 92 65 1.3e+02
[71]
ref_hepatocyte CSNK1D
Mean 18
Standard deviation 10
Values 14 6.5 13 31 25
[72]
HepG2 CSNK1D
Mean 89.7
Standard deviation 12
Values 81 98
[73]
HepG2.C3A CSNK1D
Mean 67.9
Standard deviation 18
Values 55 81
[74]
HuH.7 CSNK1D
Mean 61.3
Standard deviation 2.1
Values 64 60 60
[75]
SNU475 CSNK1D
Mean 67.2
Standard deviation 23
Values 51 84
[76]
THLE CSNK1D
Mean 54.7
Standard deviation 1
Values 54 55
[77]
liver CSNK1D
Mean 17
Standard deviation 6.7
Values 13 10 24 21
[78]
ref_hepatocyte ECE1
Mean 10.7
Standard deviation 2.1
Values 8.9 8.9 12 10 14
[79]
HepG2 ECE1
Mean 80
Standard deviation 11
Values 72 88
[80]
HepG2.C3A ECE1
Mean 60.3
Standard deviation 3.6
Values 58 63
[81]
HuH.7 ECE1
Mean 48.7
Standard deviation 6.3
Values 42 55 49
[82]
SNU475 ECE1
Mean 27.8
Standard deviation 2.7
Values 26 30
[83]
THLE ECE1
Mean 87.5
Standard deviation 4.7
Values 84 91
[84]
liver ECE1
Mean 47.9
Standard deviation 12
Values 33 43 61 53
[85]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[86]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[87]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[88]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[89]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[90]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[91]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[92]
ref_hepatocyte CSNK1E
Mean 6.27
Standard deviation 5.9
Values 16 1.4 1.9 6.5 5.5
[93]
HepG2 CSNK1E
Mean 35.7
Standard deviation 14
Values 26 45
[94]
HepG2.C3A CSNK1E
Mean 24.6
Standard deviation 8.9
Values 18 31
[95]
HuH.7 CSNK1E
Mean 37.3
Standard deviation 3.1
Values 40 37 34
[96]
SNU475 CSNK1E
Mean 15.9
Standard deviation 1.1
Values 15 17
[97]
THLE CSNK1E
Mean 37.4
Standard deviation 4.6
Values 34 41
[98]
liver CSNK1E
Mean 5.04
Standard deviation 1.3
Values 6.1 4.4 6 3.6
[99]
ref_hepatocyte ARNTL
Mean 5.32
Standard deviation 2.6
Values 4.6 7.5 7.9 1.3 5.3
[100]
HepG2 ARNTL
Mean 2.79
Standard deviation 0.22
Values 2.9 2.6
[101]
HepG2.C3A ARNTL
Mean 3.53
Standard deviation 0.11
Values 3.5 3.6
[102]
HuH.7 ARNTL
Mean 1.74
Standard deviation 0.12
Values 1.8 1.8 1.6
[103]
SNU475 ARNTL
Mean 4.73
Standard deviation 0.49
Values 5.1 4.4
[104]
THLE ARNTL
Mean 6.03
Standard deviation 0.14
Values 5.9 6.1
[105]
liver ARNTL
Mean 13.1
Standard deviation 2.3
Values 12 12 12 17
[106]
ref_hepatocyte CRY1
Mean 5.06
Standard deviation 3.6
Values 2.7 2.3 3.7 5.6 11
[107]
HepG2 CRY1
Mean 9.13
Standard deviation 1.8
Values 10 7.9
[108]
HepG2.C3A CRY1
Mean 13.2
Standard deviation 2.9
Values 11 15
[109]
HuH.7 CRY1
Mean 11.8
Standard deviation 2.2
Values 14 9.4 12
[110]
SNU475 CRY1
Mean 11.8
Standard deviation 1.6
Values 13 11
[111]
THLE CRY1
Mean 10.1
Standard deviation 0.86
Values 9.5 11
[112]
liver CRY1
Mean 7.49
Standard deviation 2.3
Values 7.4 4.4 9.4 8.9
[113]
ref_hepatocyte CRY2
Mean 4.47
Standard deviation 3.7
Values 2.6 7.8 9 1.8 1.1
[114]
HepG2 CRY2
Mean 10.4
Standard deviation 1.9
Values 12 9
[115]
HepG2.C3A CRY2
Mean 9.56
Standard deviation 2.5
Values 7.8 11
[116]
HuH.7 CRY2
Mean 27.3
Standard deviation 2.5
Values 25 30 27
[117]
SNU475 CRY2
Mean 2.08
Standard deviation 0.19
Values 2.2 1.9
[118]
THLE CRY2
Mean 4.04
Standard deviation 0.12
Values 4 4.1
[119]
liver CRY2
Mean 33.9
Standard deviation 4.4
Values 37 31 38 29
[120]
ref_hepatocyte PER1
Mean 4.3
Standard deviation 3.7
Values 7.4 3.8 8.6 0.52 1.1
[121]
HepG2 PER1
Mean 3.06
Standard deviation 0.013
Values 3.1 3
[122]
HepG2.C3A PER1
Mean 4.75
Standard deviation 1.9
Values 3.4 6.1
[123]
HuH.7 PER1
Mean 13.3
Standard deviation 2
Values 11 15 14
[124]
SNU475 PER1
Mean 2.75
Standard deviation 0.75
Values 2.2 3.3
[125]
THLE PER1
Mean 29.1
Standard deviation 0.82
Values 29 30
[126]
liver PER1
Mean 22.3
Standard deviation 13
Values 24 8.3 40 17
[127]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[128]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[129]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[130]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[131]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[132]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[133]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[134]
ref_hepatocyte EDN1
Mean 3.73
Standard deviation 6.6
Values 2.9 0.27 0.069 0.056 15
[135]
HepG2 EDN1
Mean 4.8
Standard deviation 1.5
Values 3.7 5.9
[136]
HepG2.C3A EDN1
Mean 0.366
Standard deviation 0.32
Values 0.14 0.59
[137]
HuH.7 EDN1
Mean 6.19
Standard deviation 0.93
Values 5.9 7.2 5.5
[138]
SNU475 EDN1
Mean 4.91
Standard deviation 2.4
Values 3.2 6.6
[139]
THLE EDN1
Mean 0.49
Standard deviation 0.24
Values 0.32 0.66
[140]
liver EDN1
Mean 1.29
Standard deviation 0.82
Values 0.44 1.2 1.2 2.4
[141]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.92 1.4 2.7 0.024 8
[142]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.03 0.057
[143]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.086 0.029
[144]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.95 1 0.87
[145]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 11 16
[146]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[147]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.2 7.4 6.9 9.5
[148]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 1.1 1.2 1.2 2.7 6
[149]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 43 35
[150]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 39 32
[151]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 33 44 54
[152]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 23 17
[153]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[154]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 21 17 11 4.7
[155]
ref_hepatocyte SIRT1
Mean 1.83
Standard deviation 0.67
Values 1.2 2 1.4 2.9 1.6
[156]
HepG2 SIRT1
Mean 5.71
Standard deviation 1.4
Values 6.7 4.7
[157]
HepG2.C3A SIRT1
Mean 10.9
Standard deviation 1
Values 12 10
[158]
HuH.7 SIRT1
Mean 7.67
Standard deviation 1.5
Values 6.3 9.3 7.5
[159]
SNU475 SIRT1
Mean 9.92
Standard deviation 1.6
Values 11 8.8
[160]
THLE SIRT1
Mean 13.2
Standard deviation 0.39
Values 13 13
[161]
liver SIRT1
Mean 6.57
Standard deviation 1.6
Values 7.7 6.2 7.9 4.4
[162]
ref_hepatocyte MAP2
Mean 1.78
Standard deviation 3.9
Values 0.022 0.041 0.026 0 8.8
[163]
HepG2 MAP2
Mean 0.175
Standard deviation 0.077
Values 0.12 0.23
[164]
HepG2.C3A MAP2
Mean 0.0253
Standard deviation 0.0055
Values 0.021 0.029
[165]
HuH.7 MAP2
Mean 0.335
Standard deviation 0.24
Values 0.13 0.6 0.27
[166]
SNU475 MAP2
Mean 26.6
Standard deviation 4.6
Values 23 30
[167]
THLE MAP2
Mean 22.9
Standard deviation 4.5
Values 26 20
[168]
liver MAP2
Mean 3.97
Standard deviation 1.1
Values 3.5 5.6 3.8 3
[169]
ref_hepatocyte CLOCK
Mean 1.77
Standard deviation 1.8
Values 2.2 0.24 0.53 1.2 4.8
[170]
HepG2 CLOCK
Mean 6.74
Standard deviation 3.1
Values 8.9 4.6
[171]
HepG2.C3A CLOCK
Mean 13.9
Standard deviation 3.4
Values 16 11
[172]
HuH.7 CLOCK
Mean 11.2
Standard deviation 3.9
Values 7.1 15 12
[173]
SNU475 CLOCK
Mean 16.5
Standard deviation 0.94
Values 17 16
[174]
THLE CLOCK
Mean 28.4
Standard deviation 2.1
Values 30 27
[175]
liver CLOCK
Mean 27.1
Standard deviation 6.8
Values 34 31 24 19
[176]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 2 2.6 1.9 0.71 1.7
[177]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 14 11
[178]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 7.9 10
[179]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 7.6 10 10
[180]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 6 8.6
[181]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[182]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 29 19 25 13
[183]
ref_hepatocyte ACHE
Mean 1.58
Standard deviation 1.8
Values 4.5 0.4 0.71 0.21 2.1
[184]
HepG2 ACHE
Mean 0.818
Standard deviation 0.67
Values 0.35 1.3
[185]
HepG2.C3A ACHE
Mean 0.146
Standard deviation 0.055
Values 0.11 0.18
[186]
HuH.7 ACHE
Mean 1.14
Standard deviation 0.67
Values 0.76 1.9 0.74
[187]
SNU475 ACHE
Mean 0.0812
Standard deviation 0.036
Values 0.056 0.11
[188]
THLE ACHE
Mean 0.14
Standard deviation 0.065
Values 0.095 0.19
[189]
liver ACHE
Mean 0.102
Standard deviation 0.031
Values 0.066 0.1 0.14 0.1
[190]
ref_hepatocyte PER3
Mean 1.02
Standard deviation 0.97
Values 0.85 2.7 0.68 0.45 0.41
[191]
HepG2 PER3
Mean 1.71
Standard deviation 0.19
Values 1.8 1.6
[192]
HepG2.C3A PER3
Mean 1.96
Standard deviation 0.5
Values 1.6 2.3
[193]
HuH.7 PER3
Mean 0.753
Standard deviation 0.13
Values 0.62 0.89 0.75
[194]
SNU475 PER3
Mean 9.13
Standard deviation 2.6
Values 7.3 11
[195]
THLE PER3
Mean 1.19
Standard deviation 0.17
Values 1.1 1.3
[196]
liver PER3
Mean 11.6
Standard deviation 2.9
Values 15 10 13 8.3
[197]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[198]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[199]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[200]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[201]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[202]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[203]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8
[204]
ref_hepatocyte PER2
Mean 0.849
Standard deviation 0.32
Values 1.2 0.87 1.1 0.73 0.37
[205]
HepG2 PER2
Mean 6.11
Standard deviation 1.4
Values 7.1 5.1
[206]
HepG2.C3A PER2
Mean 6.05
Standard deviation 1.6
Values 4.9 7.2
[207]
HuH.7 PER2
Mean 15.1
Standard deviation 2
Values 14 14 17
[208]
SNU475 PER2
Mean 2.03
Standard deviation 0.44
Values 2.3 1.7
[209]
THLE PER2
Mean 1.77
Standard deviation 0.31
Values 1.5 2
[210]
liver PER2
Mean 6.67
Standard deviation 4.4
Values 9 2.4 12 3.6
[211]
ref_hepatocyte ASMT
Mean 0.657
Standard deviation 0.74
Values 0 0.88 1.8 0.29 0.27
[212]
HepG2 ASMT
Missing
[213]
HepG2.C3A ASMT
Missing
[214]
HuH.7 ASMT
Missing
[215]
SNU475 ASMT
Missing
[216]
THLE ASMT
Missing
[217]
liver ASMT
Missing
[218]
ref_hepatocyte ADRB1
Mean 0.0326
Standard deviation 0.073
Values 0 0 0 0 0.16
[219]
HepG2 ADRB1
Mean 0.00429
Standard deviation 0.0061
Values 0.0086 0
[220]
HepG2.C3A ADRB1
Mean 0
Standard deviation 0
Values 0 0
[221]
HuH.7 ADRB1
Mean 0.304
Standard deviation 0.057
Values 0.34 0.24 0.34
[222]
SNU475 ADRB1
Mean 0.0865
Standard deviation 0.057
Values 0.13 0.046
[223]
THLE ADRB1
Mean 0.0118
Standard deviation 0.017
Values 0.024 0
[224]
liver ADRB1
Mean 0.208
Standard deviation 0.14
Values 0.34 0.31 0.047 0.13
[225]
ref_hepatocyte AANAT
Mean 0.00813
Standard deviation 0.018
Values 0 0.041 0 0 0
[226]
HepG2 AANAT
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[227]
HepG2.C3A AANAT
Mean 0.0593
Standard deviation 0.054
Values 0.021 0.097
[228]
HuH.7 AANAT
Mean 0.0585
Standard deviation 0.03
Values 0.084 0.026 0.066
[229]
SNU475 AANAT
Mean 0.0386
Standard deviation 0.0044
Values 0.035 0.042
[230]
THLE AANAT
Mean 0.0305
Standard deviation 0.0096
Values 0.024 0.037
[231]
liver AANAT
Mean 0.0253
Standard deviation 0.021
Values 0.026 0 0.024 0.051
[232]
ref_hepatocyte MTNR1A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 MTNR1A
Mean 0.00573
Standard deviation 0.0081
Values 0 0.011
[234]
HepG2.C3A MTNR1A
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[235]
HuH.7 MTNR1A
Mean 0.0195
Standard deviation 0.016
Values 0.037 0.013 0.0082
[236]
SNU475 MTNR1A
Mean 0.0411
Standard deviation 0.00084
Values 0.041 0.042
[237]
THLE MTNR1A
Mean 0
Standard deviation 0
Values 0 0
[238]
liver MTNR1A
Mean 0.00642
Standard deviation 0.013
Values 0 0 0 0.026
[239]
ref_hepatocyte MIR126
Missing
[240]
HepG2 MIR126
Missing
[241]
HepG2.C3A MIR126
Missing
[242]
HuH.7 MIR126
Missing
[243]
SNU475 MIR126
Missing
[244]
THLE MIR126
Missing
[245]
liver MIR126
Missing
[246]
ref_hepatocyte MIR3142HG
Missing
[247]
HepG2 MIR3142HG
Missing
[248]
HepG2.C3A MIR3142HG
Missing
[249]
HuH.7 MIR3142HG
Missing
[250]
SNU475 MIR3142HG
Missing
[251]
THLE MIR3142HG
Missing
[252]
liver MIR3142HG
Missing
[253]
ref_hepatocyte MIR146A
Missing
[254]
HepG2 MIR146A
Mean 0
Standard deviation 0
Values 0 0
[255]
HepG2.C3A MIR146A
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[256]
HuH.7 MIR146A
Mean 0
Standard deviation 0
Values 0 0 0
[257]
SNU475 MIR146A
Mean 0
Standard deviation 0
Values 0 0
[258]
THLE MIR146A
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[259]
liver MIR146A
Mean 0
Standard deviation 0
Values 0 0 0 0
[260]
ref_hepatocyte MTNR1B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[261]
HepG2 MTNR1B
Mean 0
Standard deviation 0
Values 0 0
[262]
HepG2.C3A MTNR1B
Mean 0
Standard deviation 0
Values 0 0
[263]
HuH.7 MTNR1B
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[264]
SNU475 MTNR1B
Mean 0
Standard deviation 0
Values 0 0
[265]
THLE MTNR1B
Mean 0
Standard deviation 0
Values 0 0
[266]
liver MTNR1B
Mean 0.028
Standard deviation 0.04
Values 0.026 0.086 0 0
[267]
ref_hepatocyte MIR718
Missing
[268]
HepG2 MIR718
Missing
[269]
HepG2.C3A MIR718
Missing
[270]
HuH.7 MIR718
Missing
[271]
SNU475 MIR718
Missing
[272]
THLE MIR718
Missing
[273]
liver MIR718
Missing
[274]
ref_hepatocyte CAMK2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 CAMK2A
Mean 0.0787
Standard deviation 0.022
Values 0.094 0.063
[276]
HepG2.C3A CAMK2A
Mean 0.0468
Standard deviation 0.025
Values 0.064 0.029
[277]
HuH.7 CAMK2A
Mean 0.0232
Standard deviation 0.016
Values 0.0094 0.019 0.041
[278]
SNU475 CAMK2A
Mean 1.25
Standard deviation 0.78
Values 0.69 1.8
[279]
THLE CAMK2A
Mean 0.231
Standard deviation 0.034
Values 0.21 0.26
[280]
liver CAMK2A
Mean 0.0104
Standard deviation 0.014
Values 0.013 0.029 0 0
[281]
ref_hepatocyte TPTEP2-CSNK1E
Missing
[282]
HepG2 TPTEP2-CSNK1E
Missing
[283]
HepG2.C3A TPTEP2-CSNK1E
Missing
[284]
HuH.7 TPTEP2-CSNK1E
Missing
[285]
SNU475 TPTEP2-CSNK1E
Missing
[286]
THLE TPTEP2-CSNK1E
Missing
[287]
liver TPTEP2-CSNK1E
Missing
[288]
ref_hepatocyte MIR6883
Missing
[289]
HepG2 MIR6883
Missing
[290]
HepG2.C3A MIR6883
Missing
[291]
HuH.7 MIR6883
Missing
[292]
SNU475 MIR6883
Missing
[293]
THLE MIR6883
Missing
[294]
liver MIR6883
Missing