WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RHOA | Transforming protein RhoA | [1] | -1.24[2] | -1.56[3] | -1.86[4] | -1.84[5] | -1.19[6] | -2.02[7] |
2 | STAT3 | Signal transducer and activator of transcription 3 | [8] | 0.25[9] | -1.07[10] | -0.85[11] | -0.37[12] | -0.91[13] | 1.71[14] |
3 | SHC1 | SHC-transforming protein 1 | [15] | 0.86[16] | 1.26[17] | 0.82[18] | 2.03[19] | 1.71[20] | 0.08[21] |
4 | AP2A1 | AP-2 complex subunit alpha-1 | [22] | 0.90[23] | 0.75[24] | 1.06[25] | 0.78[26] | 1.05[27] | 0.26[28] |
5 | AP2B1 | AP-2 complex subunit beta | [29] | 1.94[30] | 1.85[31] | 3.05[32] | 1.94[33] | 1.99[34] | 0.24[35] |
6 | AP2A2 | AP-2 complex subunit alpha-2 | [36] | 0.96[37] | 0.98[38] | 0.59[39] | 0.23[40] | 0.07[41] | -0.03[42] |
7 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [43] | -0.78[44] | -0.48[45] | 0.10[46] | 1.45[47] | 1.15[48] | 2.30[49] |
8 | ROCK1 | Rho-associated protein kinase 1 | [50] | -1.26[51] | 0.45[52] | 0.70[53] | 0.75[54] | 0.28[55] | 0.89[56] |
9 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -0.84[57] | 0.73[58] | 0.41[59] | -1.18[60] | 0.26[61] | 1.78[62] | |
10 | CREM | cAMP-responsive element modulator | [63] | -1.27[64] | 0.41[65] | -1.07[66] | -0.71[67] | -0.64[68] | -0.97[69] |
11 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [70] | 1.57[71] | 1.98[72] | 2.06[73] | 0.09[74] | 0.84[75] | -0.99[76] |
12 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 3.19[77] | 2.99[78] | 1.80[79] | 2.21[80] | 1.89[81] | -0.36[82] | |
13 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.91[83] | 1.60[84] | 1.24[85] | 0.43[86] | 0.78[87] | 0.46[88] | |
14 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.68[89] | 1.14[90] | 0.80[91] | 0.51[92] | 0.91[93] | 1.22[94] | |
15 | CREB1 | Cyclic AMP-responsive element-binding protein 1 | [95] | 1.42[96] | 2.76[97] | 2.73[98] | 1.93[99] | 2.06[100] | 1.64[101] |
16 | JAK2 | Tyrosine-protein kinase JAK2 | [102] | -0.08[103] | 0.10[104] | -0.86[105] | 0.15[106] | 0.94[107] | 2.01[108] |
17 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [109] | 1.42[110] | 1.61[111] | 1.94[112] | 2.55[113] | 1.76[114] | 1.98[115] |
18 | GABRB3 | Gamma-aminobutyric acid receptor subunit beta-3 | [116] | -6.57[117] | [118] | [119] | -1.34[120] | -6.69[121] | 1.17[122] |
19 | GABRE | Gamma-aminobutyric acid receptor subunit epsilon | [123] | 3.36[124] | 4.89[125] | -5.26[126] | 6.04[127] | 3.38[128] | 0.84[129] |
20 | GABRA5 | Gamma-aminobutyric acid receptor subunit alpha-5 | [130] | [131] | [132] | [133] | [134] | [135] | -3.52[136] |
21 | GABRB1 | Gamma-aminobutyric acid receptor subunit beta-1 | [137] | -6.01[138] | [139] | 2.47[140] | -4.30[141] | -6.14[142] | -2.74[143] |
22 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [144] | [145] | [146] | 0.72[147] | -3.97[148] | 3.40[149] | |
23 | BDNF | Brain-derived neurotrophic factor | [150] | -1.96[151] | -4.55[152] | -3.15[153] | 6.13[154] | 5.08[155] | 1.40[156] |
24 | GABRD | Gamma-aminobutyric acid receptor subunit delta | [157] | -2.86[158] | -4.07[159] | -5.16[160] | -5.53[161] | -5.30[162] | -1.76[163] |
25 | NGFR | Tumor necrosis factor receptor superfamily member 16 | [164] | 8.16[165] | 1.49[166] | -3.02[167] | 1.14[168] | 2.27[169] | 6.91[170] |
26 | SLC12A5 | Solute carrier family 12 member 5 | [171] | 3.98[172] | 4.03[173] | 1.38[174] | 1.30[175] | 0.20[176] | 1.76[177] |
27 | GABRA2 | Gamma-aminobutyric acid receptor subunit alpha-2 | [178] | 0.14[179] | 0.57[180] | 7.98[181] | 0.28[182] | -1.12[183] | 0.31[184] |
28 | GABRG1 | Gamma-aminobutyric acid receptor subunit gamma-1 | [185] | -0.75[186] | -1.64[187] | -3.28[188] | [189] | -2.87[190] | 1.58[191] |
29 | GABRP | Gamma-aminobutyric acid receptor subunit pi | [192] | [193] | [194] | [195] | [196] | [197] | 2.00[198] |
30 | GABRG3 | Gamma-aminobutyric acid receptor subunit gamma-3 | [199] | [200] | [201] | [202] | [203] | [204] | [205] |
31 | MIR452 | [206] | [207] | [208] | [209] | [210] | [211] | [212] | |
32 | MIR224 | [213] | [214] | [215] | [216] | [217] | [218] | [219] | |
33 | GABRA4 | Gamma-aminobutyric acid receptor subunit alpha-4 | [220] | [221] | [222] | [223] | [224] | [225] | [226] |
34 | NTRK2 | BDNF/NT-3 growth factors receptor | [227] | [228] | [229] | [230] | [231] | [232] | [233] |
35 | GABRQ | Gamma-aminobutyric acid receptor subunit theta | [234] | [235] | [236] | [237] | [238] | [239] | [240] |
36 | GABRA6 | Gamma-aminobutyric acid receptor subunit alpha-6 | [241] | [242] | [243] | [244] | [245] | [246] | [247] |
37 | GABRG2 | Gamma-aminobutyric acid receptor subunit gamma-2 | [248] | [249] | [250] | [251] | [252] | [253] | [254] |
38 | GABRA1 | Gamma-aminobutyric acid receptor subunit alpha-1 | [255] | [256] | [257] | [258] | [259] | [260] | [261] |
39 | GABRA3 | Gamma-aminobutyric acid receptor subunit alpha-3 | [262] | [263] | [264] | [265] | [266] | [267] | [268] |
40 | GABRB2 | Gamma-aminobutyric acid receptor subunit beta-2 | [269] | [270] | [271] | [272] | [273] | [274] | [275] |