WP_MAPK_AND_NFKB_SIGNALING_PATHWAYS_INHIBITED_BY_YERSINIA_YOPJ Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NFKBIA NF-kappa-B inhibitor alpha [1] -0.84[2] -2.46[3] -2.99[4] -3.04[5] -1.32[6] -1.20[7]
2 IKBKG NF-kappa-B essential modulator [8] -0.67[9] -0.35[10] -2.76[11] -0.37[12] -1.74[13] -0.67[14]
3 RAF1 RAF proto-oncogene serine/threonine-protein kinase [15] 0.15[16] 0.73[17] 1.84[18] 0.29[19] 1.00[20] 1.03[21]
4 RRAS Ras-related protein R-Ras [22] -1.27[23] -2.08[24] -1.66[25] 0.20[26] 0.05[27] -2.25[28]
5 MAPK1 Mitogen-activated protein kinase 1 [29] 1.93[30] 2.24[31] 1.91[32] 2.33[33] 1.82[34] 1.71[35]
6 NFKB1 Nuclear factor NF-kappa-B p105 subunit [36] 0.89[37] 0.74[38] 0.37[39] 0.23[40] 0.98[41] 0.39[42]
7 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [43] 1.12[44] 2.51[45] 2.32[46] 1.13[47] 1.78[48] 1.45[49]
8 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [50] 0.74[51] 0.97[52] 0.92[53] 0.74[54] 0.67[55] 1.12[56]
9 MAP3K14 Mitogen-activated protein kinase kinase kinase 14 [57] -0.18[58] 0.45[59] -0.88[60] 2.55[61] 1.38[62] 0.82[63]
10 MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 [64] 0.51[65] -2.53[66] 2.16[67] 1.49[68] -2.70[69] -1.68[70]
11 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 [71] 2.87[72] 2.76[73] 2.33[74] 2.80[75] 1.53[76] 2.74[77]
12 TRAF6 TNF receptor-associated factor 6 [78] 1.31[79] 1.37[80] 1.78[81] 2.14[82] 1.44[83] 2.85[84]
[1]
ref_hepatocyte NFKBIA
Mean 84.3
Standard deviation 48
Values 1.6e+02 40 90 83 48
[2]
HepG2 NFKBIA
Mean 89.6
Standard deviation 1.2
Values 90 89
[3]
HepG2.C3A NFKBIA
Mean 23
Standard deviation 1.2
Values 22 24
[4]
HuH.7 NFKBIA
Mean 17
Standard deviation 7.2
Values 15 25 11
[5]
SNU475 NFKBIA
Mean 13.5
Standard deviation 0.67
Values 14 13
[6]
THLE NFKBIA
Mean 55.8
Standard deviation 6.4
Values 51 60
[7]
liver NFKBIA
Mean 54.5
Standard deviation 46
Values 24 19 1.2e+02 55
[8]
ref_hepatocyte IKBKG
Mean 22.7
Standard deviation 14
Values 37 10 24 7.4 36
[9]
HepG2 IKBKG
Mean 27.1
Standard deviation 5.7
Values 23 31
[10]
HepG2.C3A IKBKG
Mean 26.7
Standard deviation 4
Values 24 30
[11]
HuH.7 IKBKG
Mean 5.4
Standard deviation 1.3
Values 6.7 4.1 5.4
[12]
SNU475 IKBKG
Mean 23.2
Standard deviation 3.5
Values 26 21
[13]
THLE IKBKG
Mean 11.2
Standard deviation 1
Values 10 12
[14]
liver IKBKG
Mean 21.3
Standard deviation 6.6
Values 13 22 20 29
[15]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 20 17 20 6 14
[16]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 36 29
[17]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 37 41
[18]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 89 93 85
[19]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 28 22
[20]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[21]
liver RAF1
Mean 47
Standard deviation 3.6
Values 46 42 51 49
[22]
ref_hepatocyte RRAS
Mean 13
Standard deviation 11
Values 16 7.6 8.2 2.5 30
[23]
HepG2 RRAS
Mean 10.3
Standard deviation 5.7
Values 6.2 14
[24]
HepG2.C3A RRAS
Mean 4.63
Standard deviation 1.6
Values 3.5 5.8
[25]
HuH.7 RRAS
Mean 6.62
Standard deviation 0.43
Values 7.1 6.2 6.6
[26]
SNU475 RRAS
Mean 19.7
Standard deviation 4
Values 17 22
[27]
THLE RRAS
Mean 22.2
Standard deviation 0.93
Values 23 22
[28]
liver RRAS
Mean 4.07
Standard deviation 3.5
Values 1.3 0.8 7.4 6.8
[29]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[30]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[31]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[32]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[33]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[34]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[35]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[36]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[37]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[38]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[39]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[40]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[41]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[42]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[43]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 2.3 4.1 3.4 4.2 5.7
[44]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 21 12
[45]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 43 25
[46]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 32 28 34
[47]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 12 11
[48]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[49]
liver CHUK
Mean 16
Standard deviation 3.3
Values 15 21 13 15
[50]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[51]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[52]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[53]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[54]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[55]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[56]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[57]
ref_hepatocyte MAP3K14
Mean 1.9
Standard deviation 1.1
Values 3.6 1.1 1.7 0.92 2.2
[58]
HepG2 MAP3K14
Mean 3.19
Standard deviation 0.37
Values 2.9 3.4
[59]
HepG2.C3A MAP3K14
Mean 3.89
Standard deviation 0.18
Values 3.8 4
[60]
HuH.7 MAP3K14
Mean 1.66
Standard deviation 0.35
Values 1.8 1.9 1.3
[61]
SNU475 MAP3K14
Mean 14.7
Standard deviation 3
Values 17 13
[62]
THLE MAP3K14
Mean 8.14
Standard deviation 0.86
Values 8.8 7.5
[63]
liver MAP3K14
Mean 4.97
Standard deviation 1.7
Values 6.4 4.3 2.9 6.3
[64]
ref_hepatocyte MAP2K6
Mean 1.65
Standard deviation 2.1
Values 0.17 1.1 0.98 5.3 0.69
[65]
HepG2 MAP2K6
Mean 4.46
Standard deviation 1.8
Values 5.7 3.2
[66]
HepG2.C3A MAP2K6
Mean 0.428
Standard deviation 0.00091
Values 0.43 0.43
[67]
HuH.7 MAP2K6
Mean 11.9
Standard deviation 2.1
Values 13 9.5 13
[68]
SNU475 MAP2K6
Mean 6.1
Standard deviation 1.1
Values 5.4 6.8
[69]
THLE MAP2K6
Mean 0.418
Standard deviation 0.064
Values 0.37 0.46
[70]
liver MAP2K6
Mean 0.764
Standard deviation 0.64
Values 0.79 0.61 1.6 0.051
[71]
ref_hepatocyte MAP3K1
Mean 1.15
Standard deviation 0.91
Values 1.1 0.9 0.47 2.7 0.56
[72]
HepG2 MAP3K1
Mean 16
Standard deviation 5.2
Values 20 12
[73]
HepG2.C3A MAP3K1
Mean 11.7
Standard deviation 2.9
Values 14 9.6
[74]
HuH.7 MAP3K1
Mean 9.28
Standard deviation 2.5
Values 6.5 11 10
[75]
SNU475 MAP3K1
Mean 10.6
Standard deviation 2.4
Values 8.9 12
[76]
THLE MAP3K1
Mean 5.47
Standard deviation 0.12
Values 5.5 5.4
[77]
liver MAP3K1
Mean 11.4
Standard deviation 4.8
Values 14 17 7.7 7
[78]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[79]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[80]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[81]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[82]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[83]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[84]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8