WP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RHOA Transforming protein RhoA [1] -1.04[2] -1.32[3] -1.47[4] -0.86[5] -0.54[6] -1.17[7]
2 GADD45G Growth arrest and DNA damage-inducible protein GADD45 gamma [8] -10.02[9] [10] -8.65[11] -7.47[12] -7.54[13] -1.57[14]
3 CTNNB1 Catenin beta-1 [15] 1.52[16] 1.23[17] 1.75[18] 1.12[19] 1.21[20] 1.26[21]
4 MAPK1 Mitogen-activated protein kinase 1 [22] 1.61[23] 1.97[24] 1.42[25] 2.21[26] 1.73[27] 1.93[28]
5 ROCK1 Rho-associated protein kinase 1 [29] -1.05[30] 0.69[31] 1.09[32] 1.72[33] 0.94[34] 1.73[35]
6 SOX9 Transcription factor SOX-9 [36] 2.26[37] 2.62[38] 2.08[39] -0.57[40] -1.45[41] -2.98[42]
7 AXIN1 Axin-1 [43] 1.25[44] 1.79[45] -0.15[46] -8.34[47] 0.38[48] -0.50[49]
8 GSK3B Glycogen synthase kinase-3 beta [50] 1.17[51] 1.02[52] 1.22[53] 2.18[54] 1.87[55] 1.31[56]
9 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 [57] 0.85[58] 1.74[59] 0.51[60] 1.22[61] 1.38[62] 1.55[63]
10 FGFR2 Fibroblast growth factor receptor 2 [64] -2.61[65] -1.18[66] 2.38[67] 1.82[68] -3.16[69] 3.57[70]
11 FRAT1 Proto-oncogene FRAT1 [71] 0.59[72] 0.57[73] 2.30[74] -2.19[75] -1.14[76] 0.63[77]
12 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 [78] 2.55[79] 2.48[80] 1.84[81] 2.68[82] 1.43[83] 2.95[84]
13 MAPK11 Mitogen-activated protein kinase 11 [85] -0.27[86] -0.16[87] -1.42[88] 0.72[89] 2.58[90] 0.32[91]
14 WNT4 Protein Wnt-4 [92] -3.79[93] -2.71[94] -4.19[95] -1.00[96] -2.46[97] 0.36[98]
15 SRY Sex-determining region Y protein [99] 1.16[100] 1.35[101] [102] [103] [104] [105]
16 FGF9 Fibroblast growth factor 9 [106] 2.16[107] -1.28[108] [109] 3.14[110] -2.10[111] 0.26[112]
17 FOXL2 Forkhead box protein L2 [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 1.4e+02 79 75 2.2e+02 3.8e+02
[2]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 1.8e+02 2.3e+02
[3]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[4]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[5]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.2e+02 1.5e+02
[6]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[7]
liver RHOA
Mean 101
Standard deviation 59
Values 46 54 1.6e+02 1.4e+02
[8]
ref_hepatocyte GADD45G
Mean 40.5
Standard deviation 54
Values 13 61 1.3e+02 0 1.8
[9]
HepG2 GADD45G
Mean 0.0924
Standard deviation 0.088
Values 0.03 0.15
[10]
HepG2.C3A GADD45G
Mean 0
Standard deviation 0
Values 0 0
[11]
HuH.7 GADD45G
Mean 0.228
Standard deviation 0.25
Values 0.11 0.51 0.057
[12]
SNU475 GADD45G
Mean 0.326
Standard deviation 0.048
Values 0.36 0.29
[13]
THLE GADD45G
Mean 0.382
Standard deviation 0.029
Values 0.4 0.36
[14]
liver GADD45G
Mean 17.4
Standard deviation 13
Values 3.3 9.9 30 27
[15]
ref_hepatocyte CTNNB1
Mean 37.2
Standard deviation 16
Values 22 31 23 57 53
[16]
HepG2 CTNNB1
Mean 252
Standard deviation 27
Values 2.7e+02 2.3e+02
[17]
HepG2.C3A CTNNB1
Mean 158
Standard deviation 34
Values 1.8e+02 1.3e+02
[18]
HuH.7 CTNNB1
Mean 282
Standard deviation 64
Values 3.1e+02 2.1e+02 3.3e+02
[19]
SNU475 CTNNB1
Mean 115
Standard deviation 10
Values 1.1e+02 1.2e+02
[20]
THLE CTNNB1
Mean 151
Standard deviation 19
Values 1.4e+02 1.6e+02
[21]
liver CTNNB1
Mean 114
Standard deviation 15
Values 1.1e+02 1.3e+02 98 1.2e+02
[22]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[23]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[24]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[25]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[26]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[27]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[28]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[29]
ref_hepatocyte ROCK1
Mean 6.73
Standard deviation 4.9
Values 3.6 3.9 2.5 9.7 14
[30]
HepG2 ROCK1
Mean 7.68
Standard deviation 2.4
Values 9.4 6
[31]
HepG2.C3A ROCK1
Mean 19.7
Standard deviation 1.6
Values 21 19
[32]
HuH.7 ROCK1
Mean 32.3
Standard deviation 9
Values 22 39 36
[33]
SNU475 ROCK1
Mean 31.8
Standard deviation 1.6
Values 33 31
[34]
THLE ROCK1
Mean 22.6
Standard deviation 6.2
Values 27 18
[35]
liver ROCK1
Mean 28.7
Standard deviation 3.4
Values 27 32 30 25
[36]
ref_hepatocyte SOX9
Mean 6.44
Standard deviation 14
Values 0.63 0.27 0.17 31 0.028
[37]
HepG2 SOX9
Mean 73.1
Standard deviation 8
Values 67 79
[38]
HepG2.C3A SOX9
Mean 71.7
Standard deviation 24
Values 55 89
[39]
HuH.7 SOX9
Mean 61.6
Standard deviation 13
Values 60 50 75
[40]
SNU475 SOX9
Mean 6.21
Standard deviation 0.59
Values 5.8 6.6
[41]
THLE SOX9
Mean 4.14
Standard deviation 0.56
Values 4.5 3.7
[42]
liver SOX9
Mean 1.05
Standard deviation 0.26
Values 1.4 0.96 0.78 1.1
[43]
ref_hepatocyte AXIN1
Mean 4.86
Standard deviation 2.8
Values 7.6 1.6 2.2 6.8 6.1
[44]
HepG2 AXIN1
Mean 27.3
Standard deviation 5.7
Values 23 31
[45]
HepG2.C3A AXIN1
Mean 30.4
Standard deviation 14
Values 21 40
[46]
HuH.7 AXIN1
Mean 9.87
Standard deviation 0.66
Values 10 10 9.1
[47]
SNU475 AXIN1
Mean 0.0215
Standard deviation 0.0089
Values 0.015 0.028
[48]
THLE AXIN1
Mean 11.1
Standard deviation 0.85
Values 11 12
[49]
liver AXIN1
Mean 4.4
Standard deviation 1.7
Values 6.6 4.8 3.3 2.9
[50]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[51]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[52]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[53]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[54]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[55]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[56]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[57]
ref_hepatocyte MAP3K4
Mean 2.86
Standard deviation 1.8
Values 2.4 2 1.7 6.1 2.1
[58]
HepG2 MAP3K4
Mean 12.2
Standard deviation 2.8
Values 14 10
[59]
HepG2.C3A MAP3K4
Mean 17.3
Standard deviation 1.7
Values 16 19
[60]
HuH.7 MAP3K4
Mean 9.18
Standard deviation 1.1
Values 7.9 10 9.5
[61]
SNU475 MAP3K4
Mean 9.53
Standard deviation 1.1
Values 10 8.8
[62]
THLE MAP3K4
Mean 13.1
Standard deviation 1.2
Values 12 14
[63]
liver MAP3K4
Mean 10.7
Standard deviation 4.6
Values 14 15 7.3 6.1
[64]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.084 3.2 2.4 0.47 0.46
[65]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.73 0.3
[66]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 1.3 0.86
[67]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[68]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 2.2 11
[69]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[70]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 32 19 18 13
[71]
ref_hepatocyte FRAT1
Mean 1.33
Standard deviation 1.3
Values 0.65 3.1 2.2 0.49 0.18
[72]
HepG2 FRAT1
Mean 4.74
Standard deviation 2.2
Values 3.2 6.3
[73]
HepG2.C3A FRAT1
Mean 3.57
Standard deviation 0.98
Values 2.9 4.3
[74]
HuH.7 FRAT1
Mean 14.7
Standard deviation 1.5
Values 16 15 13
[75]
SNU475 FRAT1
Mean 0.414
Standard deviation 0.0089
Values 0.42 0.41
[76]
THLE FRAT1
Mean 1.06
Standard deviation 0.11
Values 0.98 1.1
[77]
liver FRAT1
Mean 2.62
Standard deviation 1.5
Values 4.2 2.7 2.9 0.62
[78]
ref_hepatocyte MAP3K1
Mean 1.15
Standard deviation 0.91
Values 1.1 0.9 0.47 2.7 0.56
[79]
HepG2 MAP3K1
Mean 16
Standard deviation 5.2
Values 20 12
[80]
HepG2.C3A MAP3K1
Mean 11.7
Standard deviation 2.9
Values 14 9.6
[81]
HuH.7 MAP3K1
Mean 9.28
Standard deviation 2.5
Values 6.5 11 10
[82]
SNU475 MAP3K1
Mean 10.6
Standard deviation 2.4
Values 8.9 12
[83]
THLE MAP3K1
Mean 5.47
Standard deviation 0.12
Values 5.5 5.4
[84]
liver MAP3K1
Mean 11.4
Standard deviation 4.8
Values 14 17 7.7 7
[85]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0.22 0.64 0.71 0 0.34
[86]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.88 0.62
[87]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.71 0.53
[88]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.49 0.2 0.28
[89]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 0.66 1.1
[90]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[91]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.75 0.49 0.96 0.23
[92]
ref_hepatocyte WNT4
Mean 0.276
Standard deviation 0.47
Values 0.3 0 1.1 0 0
[93]
HepG2 WNT4
Mean 0.0472
Standard deviation 0.0061
Values 0.043 0.052
[94]
HepG2.C3A WNT4
Mean 0.0764
Standard deviation 0.0019
Values 0.075 0.078
[95]
HuH.7 WNT4
Mean 0.034
Standard deviation 0.022
Values 0.056 0.013 0.033
[96]
SNU475 WNT4
Mean 0.197
Standard deviation 0.1
Values 0.27 0.13
[97]
THLE WNT4
Mean 0.0881
Standard deviation 0.034
Values 0.11 0.064
[98]
liver WNT4
Mean 0.454
Standard deviation 0.67
Values 1.4 0.3 0.024 0.051
[99]
ref_hepatocyte SRY
Mean 0.0268
Standard deviation 0.06
Values 0 0 0 0.13 0
[100]
HepG2 SRY
Mean 0.142
Standard deviation 0.13
Values 0.23 0.052
[101]
HepG2.C3A SRY
Mean 0.124
Standard deviation 0.037
Values 0.15 0.097
[102]
HuH.7 SRY
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 SRY
Mean 0
Standard deviation 0
Values 0 0
[104]
THLE SRY
Mean 0
Standard deviation 0
Values 0 0
[105]
liver SRY
Mean 0
Standard deviation 0
Values 0 0 0 0
[106]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[107]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[108]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[109]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.025 0.14
[111]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[112]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0.04 0 0 0
[113]
ref_hepatocyte FOXL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 FOXL2
Mean 0.0558
Standard deviation 0.055
Values 0.094 0.017
[115]
HepG2.C3A FOXL2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[116]
HuH.7 FOXL2
Mean 0.136
Standard deviation 0.033
Values 0.15 0.16 0.098
[117]
SNU475 FOXL2
Mean 2.71
Standard deviation 0.15
Values 2.8 2.6
[118]
THLE FOXL2
Mean 1.6
Standard deviation 0.29
Values 1.4 1.8
[119]
liver FOXL2
Mean 0
Standard deviation 0
Values 0 0 0 0