WP_LUNG_FIBROSIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SERPINA1 | Alpha-1-antitrypsin | [1] | -0.08[2] | 0.22[3] | 0.09[4] | -8.01[5] | -7.43[6] | 0.43[7] |
2 | MT2A | Metallothionein-2 | [8] | -3.79[9] | -4.17[10] | -7.08[11] | -4.22[12] | 0.69[13] | -2.62[14] |
3 | TIMP1 | Metalloproteinase inhibitor 1 | [15] | 0.46[16] | -1.52[17] | -7.28[18] | 2.64[19] | 3.37[20] | 0.17[21] |
4 | CXCL2 | C-X-C motif chemokine 2 | [22] | -4.79[23] | -5.69[24] | -2.93[25] | -2.72[26] | 0.62[27] | 0.62[28] |
5 | HMOX1 | Heme oxygenase 1 | [29] | 2.21[30] | 0.92[31] | 1.23[32] | 3.01[33] | 1.92[34] | -1.87[35] |
6 | CEBPB | CCAAT/enhancer-binding protein beta | [36] | 1.52[37] | 0.52[38] | 1.97[39] | 3.19[40] | 3.27[41] | -1.46[42] |
7 | SPP1 | Osteopontin | [43] | 5.87[44] | 4.27[45] | -2.80[46] | 6.50[47] | -2.42[48] | -0.86[49] |
8 | IGF1 | Insulin-like growth factor I | [50] | -5.73[51] | -7.03[52] | -3.82[53] | 3.07[54] | -5.62[55] | 1.14[56] |
9 | NFE2L2 | Nuclear factor erythroid 2-related factor 2 | [57] | 3.46[58] | 4.03[59] | 5.05[60] | 5.07[61] | 4.45[62] | 0.39[63] |
10 | DPP9 | Dipeptidyl peptidase 9 | [64] | 3.02[65] | 2.12[66] | 4.27[67] | 4.01[68] | 3.70[69] | 0.93[70] |
11 | DSP | Desmoplakin | [71] | 5.74[72] | 5.70[73] | 5.66[74] | 5.19[75] | 1.48[76] | 3.05[77] |
12 | CCL2 | C-C motif chemokine 2 | [78] | -10.70[79] | [80] | -9.07[81] | 0.49[82] | 1.80[83] | -3.47[84] |
13 | PARN | Poly(A)-specific ribonuclease PARN | [85] | 3.62[86] | 2.61[87] | 3.68[88] | 4.56[89] | 3.67[90] | 0.16[91] |
14 | ELMOD2 | ELMO domain-containing protein 2 | [92] | 2.15[93] | 3.61[94] | 4.74[95] | 4.00[96] | 3.81[97] | 0.56[98] |
15 | CCL3 | C-C motif chemokine 3 | [99] | [100] | [101] | [102] | -3.59[103] | [104] | -4.20[105] |
16 | CCL4 | C-C motif chemokine 4 | [106] | [107] | [108] | [109] | [110] | [111] | -3.19[112] |
17 | CALCA | Calcitonin | [113] | [114] | [115] | -6.68[116] | [117] | -5.40[118] | -0.88[119] |
18 | MECP2 | Methyl-CpG-binding protein 2 | [120] | 3.42[121] | 3.35[122] | 4.97[123] | 6.19[124] | 5.44[125] | 1.05[126] |
19 | CCL5 | C-C motif chemokine 5 | [127] | -2.07[128] | -1.89[129] | -0.31[130] | 0.90[131] | -1.14[132] | 0.94[133] |
20 | FAM13A | Protein FAM13A | [134] | 1.42[135] | 2.79[136] | 6.14[137] | 4.26[138] | 3.53[139] | 2.06[140] |
21 | FGF2 | Fibroblast growth factor 2 | [141] | -4.00[142] | -4.10[143] | 1.47[144] | 5.54[145] | 6.26[146] | -1.45[147] |
22 | SMAD7 | Mothers against decapentaplegic homolog 7 | [148] | 4.55[149] | 2.30[150] | 2.71[151] | 5.19[152] | 4.03[153] | 0.22[154] |
23 | EDN1 | Endothelin-1 | [155] | 1.91[156] | -1.99[157] | 3.57[158] | 4.12[159] | -0.22[160] | -1.82[161] |
24 | ATP11A | Probable phospholipid-transporting ATPase IH | [162] | 5.30[163] | 5.09[164] | 5.89[165] | 5.73[166] | 6.29[167] | 2.63[168] |
25 | IL1B | Interleukin-1 beta | [169] | -6.01[170] | -6.23[171] | -0.49[172] | 1.01[173] | 5.75[174] | -4.98[175] |
26 | TGFB1 | Transforming growth factor beta-1 | [176] | 6.16[177] | 4.76[178] | 3.44[179] | 8.44[180] | 6.82[181] | -1.01[182] |
27 | SKIL | Ski-like protein | [183] | 4.35[184] | 4.03[185] | 6.90[186] | 7.24[187] | 6.41[188] | 3.37[189] |
28 | TGFA | Protransforming growth factor alpha | [190] | 4.48[191] | 5.19[192] | -4.44[193] | 3.64[194] | 1.56[195] | -0.18[196] |
29 | PDGFA | Platelet-derived growth factor subunit A | [197] | 1.69[198] | 1.54[199] | 5.04[200] | 4.26[201] | 2.50[202] | -0.53[203] |
30 | CSF3 | Granulocyte colony-stimulating factor | [204] | 0.52[205] | -3.45[206] | -2.44[207] | -2.34[208] | 8.20[209] | -7.20[210] |
31 | RTEL1 | Regulator of telomere elongation helicase 1 | [211] | 0.99[212] | 1.76[213] | 1.37[214] | 2.32[215] | 2.04[216] | -1.43[217] |
32 | IL6 | Interleukin-6 | [218] | -5.75[219] | [220] | -1.08[221] | 3.75[222] | 5.41[223] | [224] |
33 | PLAU | Urokinase-type plasminogen activator | [225] | 2.96[226] | -1.52[227] | 1.05[228] | 6.93[229] | 4.09[230] | -1.78[231] |
34 | MMP9 | Matrix metalloproteinase-9 | [232] | -0.03[233] | -1.44[234] | -2.41[235] | 3.17[236] | -0.24[237] | 0.08[238] |
35 | PDGFB | Platelet-derived growth factor subunit B | [239] | 5.75[240] | 5.25[241] | 3.86[242] | 4.67[243] | 3.39[244] | 0.59[245] |
36 | FGF7 | Fibroblast growth factor 7 | [246] | -6.60[247] | -3.26[248] | [249] | -0.77[250] | 2.64[251] | -1.23[252] |
37 | CCR2 | C-C chemokine receptor type 2 | [253] | [254] | [255] | 3.48[256] | [257] | [258] | 1.08[259] |
38 | GREM1 | Gremlin-1 | [260] | 0.51[261] | -1.72[262] | 1.27[263] | 12.44[264] | 7.79[265] | 0.67[266] |
39 | ELN | Elastin | [267] | 0.95[268] | 2.82[269] | -4.12[270] | 2.51[271] | -0.10[272] | 3.59[273] |
40 | CMA1 | Chymase | [274] | -2.15[275] | -4.29[276] | [277] | -3.13[278] | [279] | -2.15[280] |
41 | BMP7 | Bone morphogenetic protein 7 | [281] | 1.20[282] | 1.65[283] | 2.89[284] | 3.97[285] | 2.73[286] | -0.94[287] |
42 | PTX3 | Pentraxin-related protein PTX3 | [288] | 0.21[289] | -1.61[290] | 2.27[291] | 8.80[292] | 11.89[293] | -1.28[294] |
43 | MMP2 | 72 kDa type IV collagenase | [295] | 6.13[296] | -1.22[297] | 1.48[298] | 12.04[299] | 10.74[300] | 4.15[301] |
44 | FGF1 | Fibroblast growth factor 1 | [302] | -0.07[303] | 0.36[304] | -2.69[305] | 5.19[306] | 5.92[307] | 0.26[308] |
45 | TERT | Telomerase reverse transcriptase | [309] | 6.18[310] | 5.58[311] | 7.94[312] | 6.79[313] | -0.11[314] | -3.68[315] |
46 | TNF | Tumor necrosis factor | [316] | 3.79[317] | 1.30[318] | -1.88[319] | 2.38[320] | -1.69[321] | -1.67[322] |
47 | MUC5B | Mucin-5B | [323] | 4.98[324] | 3.31[325] | 2.76[326] | 4.65[327] | 0.61[328] | 4.14[329] |
48 | CSF2 | Granulocyte-macrophage colony-stimulating factor | [330] | 3.15[331] | -1.16[332] | 0.90[333] | 2.89[334] | 9.93[335] | -1.26[336] |
49 | HGF | Hepatocyte growth factor | [337] | [338] | [339] | 2.10[340] | 9.20[341] | 5.37[342] | 9.11[343] |
50 | CYSLTR2 | Cysteinyl leukotriene receptor 2 | [344] | [345] | 0.93[346] | [347] | 2.37[348] | 2.57[349] | 2.66[350] |
51 | EGF | Pro-epidermal growth factor | [351] | 4.66[352] | 6.09[353] | 11.12[354] | 13.63[355] | 10.19[356] | 1.80[357] |
52 | SFTPA1 | Pulmonary surfactant-associated protein A1 | [358] | [359] | [360] | [361] | [362] | [363] | [364] |
53 | CXCL8 | Interleukin-8 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | IL4 | Interleukin-4 | [372] | [373] | [374] | [375] | [376] | [377] | [378] |
55 | STN1 | CST complex subunit STN1 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | CCN2 | [386] | [387] | [388] | [389] | [390] | [391] | [392] | |
57 | IL13 | Interleukin-13 | [393] | [394] | [395] | [396] | [397] | [398] | [399] |
58 | SFTPC | Pulmonary surfactant-associated protein C | [400] | [401] | [402] | [403] | [404] | [405] | [406] |
59 | IL12B | Interleukin-12 subunit beta | [407] | [408] | [409] | [410] | [411] | [412] | [413] |
60 | CCR3 | C-C chemokine receptor type 3 | [414] | [415] | [416] | [417] | [418] | [419] | [420] |
61 | SFTPA2 | Pulmonary surfactant-associated protein A2 | [421] | [422] | [423] | [424] | [425] | [426] | [427] |
62 | IL5 | Interleukin-5 | [428] | [429] | [430] | [431] | [432] | [433] | [434] |
63 | CCL11 | Eotaxin | [435] | [436] | [437] | [438] | [439] | [440] | [441] |