WP_LTF_DANGER_SIGNAL_RESPONSE_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CD14 Monocyte differentiation antigen CD14 [1] -7.52[2] -7.41[3] -4.21[4] -3.76[5] -5.53[6] -0.54[7]
2 IRAK1 Interleukin-1 receptor-associated kinase 1 [8] 2.23[9] 1.81[10] 1.18[11] 1.84[12] 1.62[13] -0.72[14]
3 MYD88 Myeloid differentiation primary response protein MyD88 [15] 0.63[16] 0.87[17] 0.69[18] 0.01[19] -0.28[20] 0.76[21]
4 MAPK1 Mitogen-activated protein kinase 1 [22] 2.52[23] 2.84[24] 3.06[25] 2.89[26] 1.96[27] 1.74[28]
5 NFKB1 Nuclear factor NF-kappa-B p105 subunit [29] 1.48[30] 1.34[31] 1.52[32] 0.80[33] 1.12[34] 0.42[35]
6 IL1B Interleukin-1 beta [36] -7.88[37] -7.57[38] -2.86[39] -2.55[40] 2.46[41] -5.23[42]
7 TLR2 Toll-like receptor 2 [43] -2.73[44] -1.13[45] -7.74[46] -3.93[47] 2.24[48] 1.21[49]
8 IRAK4 Interleukin-1 receptor-associated kinase 4 [50] 1.07[51] 2.62[52] 3.28[53] 2.46[54] 1.63[55] 1.75[56]
9 IL6 Interleukin-6 [57] -7.63[58] [59] -3.45[60] 0.19[61] 2.12[62] [63]
10 TRAF6 TNF receptor-associated factor 6 [64] 1.90[65] 1.98[66] 2.93[67] 2.71[68] 1.57[69] 2.88[70]
11 TLR4 Toll-like receptor 4 [71] 1.08[72] -3.88[73] -4.39[74] -4.05[75] 5.78[76] 4.43[77]
12 AGER Advanced glycosylation end product-specific receptor [78] -0.23[79] 3.13[80] 2.44[81] 1.69[82] 0.86[83] -0.14[84]
13 TNF Tumor necrosis factor [85] 1.91[86] -0.04[87] -4.25[88] -1.18[89] -4.99[90] -1.93[91]
14 TREM1 Triggering receptor expressed on myeloid cells 1 [92] 2.32[93] -1.74[94] [95] 0.33[96] 3.75[97] 0.87[98]
15 IL1A Interleukin-1 alpha [99] 0.39[100] 0.17[101] -0.62[102] 0.40[103] 6.57[104] -1.62[105]
16 LTF Lactotransferrin [106] -3.57[107] [108] 2.01[109] [110] -1.64[111] 3.59[112]
17 CXCL8 Interleukin-8 [113] [114] [115] [116] [117] [118] [119]
18 MIR718 [120] [121] [122] [123] [124] [125] [126]
19 IFNA1 Interferon alpha-1/13 [127] [128] [129] [130] [131] [132] [133]
20 IFNB1 Interferon beta [134] [135] [136] [137] [138] [139] [140]
[1]
ref_hepatocyte CD14
Mean 148
Standard deviation 1.9e+02
Values 16 3.8e+02 3.4e+02 0.7 1.6
[2]
HepG2 CD14
Mean 1.01
Standard deviation 0.084
Values 0.95 1.1
[3]
HepG2.C3A CD14
Mean 0.856
Standard deviation 0.32
Values 0.63 1.1
[4]
HuH.7 CD14
Mean 5.78
Standard deviation 1.1
Values 6.9 4.7 5.8
[5]
SNU475 CD14
Mean 9.74
Standard deviation 1.9
Values 11 8.4
[6]
THLE CD14
Mean 4.8
Standard deviation 0.97
Values 5.5 4.1
[7]
liver CD14
Mean 148
Standard deviation 88
Values 77 68 2.1e+02 2.4e+02
[8]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 38 5 16 18 30
[9]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 97 1.5e+02
[10]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 75 72
[11]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 34 31 40
[12]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 78 58
[13]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[14]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 24 19 17 15
[15]
ref_hepatocyte MYD88
Mean 12.3
Standard deviation 6.2
Values 14 17 19 5.4 6
[16]
HepG2 MYD88
Mean 23.8
Standard deviation 12
Values 32 16
[17]
HepG2.C3A MYD88
Mean 22.1
Standard deviation 5.1
Values 26 18
[18]
HuH.7 MYD88
Mean 14.3
Standard deviation 1.1
Values 15 13 15
[19]
SNU475 MYD88
Mean 11
Standard deviation 1.1
Values 10 12
[20]
THLE MYD88
Mean 15.1
Standard deviation 1.7
Values 14 16
[21]
liver MYD88
Mean 30.3
Standard deviation 21
Values 14 9.8 47 51
[22]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[23]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[24]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[25]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[26]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[27]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[28]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[29]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[30]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[31]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[32]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[33]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[34]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[35]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[36]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[37]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[38]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[39]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[40]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[41]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[42]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[43]
ref_hepatocyte TLR2
Mean 1.56
Standard deviation 1.2
Values 2.3 1.4 3.1 0 0.96
[44]
HepG2 TLR2
Mean 0.296
Standard deviation 0.084
Values 0.24 0.36
[45]
HepG2.C3A TLR2
Mean 0.704
Standard deviation 0.0056
Values 0.71 0.7
[46]
HuH.7 TLR2
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[47]
SNU475 TLR2
Mean 0.0914
Standard deviation 0.057
Values 0.13 0.051
[48]
THLE TLR2
Mean 11.1
Standard deviation 4.3
Values 14 8.1
[49]
liver TLR2
Mean 5.26
Standard deviation 1.6
Values 5.9 6.8 3.2 5.1
[50]
ref_hepatocyte IRAK4
Mean 1.45
Standard deviation 0.56
Values 0.79 1.9 2.1 1.6 0.94
[51]
HepG2 IRAK4
Mean 3.82
Standard deviation 0.94
Values 4.5 3.2
[52]
HepG2.C3A IRAK4
Mean 8.76
Standard deviation 1.5
Values 9.8 7.7
[53]
HuH.7 IRAK4
Mean 10.2
Standard deviation 0.57
Values 9.8 11 9.9
[54]
SNU475 IRAK4
Mean 7.11
Standard deviation 2.2
Values 5.5 8.7
[55]
THLE IRAK4
Mean 6.73
Standard deviation 0.64
Values 6.3 7.2
[56]
liver IRAK4
Mean 7.06
Standard deviation 1.8
Values 7.5 9.3 5.4 6
[57]
ref_hepatocyte IL6
Mean 1.35
Standard deviation 2.5
Values 5.9 0.28 0.6 0 0
[58]
HepG2 IL6
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[59]
HepG2.C3A IL6
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 IL6
Mean 0.0895
Standard deviation 0.012
Values 0.1 0.083 0.082
[61]
SNU475 IL6
Mean 1.37
Standard deviation 1.7
Values 2.6 0.15
[62]
THLE IL6
Mean 8.81
Standard deviation 1.5
Values 7.7 9.9
[63]
liver IL6
Mean 0
Standard deviation 0
Values 0 0 0 0
[64]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[65]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[66]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[67]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[68]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[69]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[70]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8
[71]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0.33 0.66 0.64 0 1.1
[72]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 2.1 0.82
[73]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.054 0.019
[74]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0.037 0.019 0
[75]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.035 0.023
[76]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[77]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 25 19 13 11
[78]
ref_hepatocyte AGER
Mean 0.428
Standard deviation 0.33
Values 0 0.79 0.53 0.64 0.18
[79]
HepG2 AGER
Mean 0.458
Standard deviation 0.017
Values 0.45 0.47
[80]
HepG2.C3A AGER
Mean 3.68
Standard deviation 1.8
Values 2.4 5
[81]
HuH.7 AGER
Mean 1.68
Standard deviation 0.57
Values 2.3 1.5 1.2
[82]
SNU475 AGER
Mean 1.23
Standard deviation 0.34
Values 0.98 1.5
[83]
THLE AGER
Mean 1.17
Standard deviation 0.6
Values 1.6 0.74
[84]
liver AGER
Mean 0.565
Standard deviation 0.23
Values 0.9 0.5 0.42 0.44
[85]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[86]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[87]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[88]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[89]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[90]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[91]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[92]
ref_hepatocyte TREM1
Mean 0.0712
Standard deviation 0.11
Values 0 0.098 0.26 0 0
[93]
HepG2 TREM1
Mean 0.447
Standard deviation 0.63
Values 0 0.89
[94]
HepG2.C3A TREM1
Mean 0.0209
Standard deviation 0.016
Values 0.032 0.0097
[95]
HuH.7 TREM1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 TREM1
Mean 0.0798
Standard deviation 0.074
Values 0.13 0.028
[97]
THLE TREM1
Mean 1.44
Standard deviation 1.2
Values 2.3 0.63
[98]
liver TREM1
Mean 0.189
Standard deviation 0.084
Values 0.3 0.19 0.16 0.1
[99]
ref_hepatocyte IL1A
Mean 0.05
Standard deviation 0.11
Values 0.25 0 0 0 0
[100]
HepG2 IL1A
Mean 0.0823
Standard deviation 0.035
Values 0.11 0.057
[101]
HepG2.C3A IL1A
Mean 0.0555
Standard deviation 0.018
Values 0.043 0.068
[102]
HuH.7 IL1A
Mean 0.0235
Standard deviation 0.041
Values 0 0.071 0
[103]
SNU475 IL1A
Mean 0.0589
Standard deviation 0.024
Values 0.076 0.042
[104]
THLE IL1A
Mean 7.11
Standard deviation 1.8
Values 8.4 5.8
[105]
liver IL1A
Mean 0.0237
Standard deviation 0.034
Values 0 0.071 0.024 0
[106]
ref_hepatocyte LTF
Mean 0.0475
Standard deviation 0.067
Values 0 0.098 0 0 0.14
[107]
HepG2 LTF
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[108]
HepG2.C3A LTF
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 LTF
Mean 0.138
Standard deviation 0.041
Values 0.18 0.096 0.14
[110]
SNU475 LTF
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE LTF
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[112]
liver LTF
Mean 0.832
Standard deviation 0.67
Values 0.4 1.6 0.14 1.2
[113]
ref_hepatocyte CXCL8
Missing
[114]
HepG2 CXCL8
Missing
[115]
HepG2.C3A CXCL8
Missing
[116]
HuH.7 CXCL8
Missing
[117]
SNU475 CXCL8
Missing
[118]
THLE CXCL8
Missing
[119]
liver CXCL8
Missing
[120]
ref_hepatocyte MIR718
Missing
[121]
HepG2 MIR718
Missing
[122]
HepG2.C3A MIR718
Missing
[123]
HuH.7 MIR718
Missing
[124]
SNU475 MIR718
Missing
[125]
THLE MIR718
Missing
[126]
liver MIR718
Missing
[127]
ref_hepatocyte IFNA1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 IFNA1
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A IFNA1
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 IFNA1
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 IFNA1
Mean 0.00485
Standard deviation 0.0003
Values 0.0051 0.0046
[132]
THLE IFNA1
Mean 0
Standard deviation 0
Values 0 0
[133]
liver IFNA1
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte IFNB1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 IFNB1
Missing
[136]
HepG2.C3A IFNB1
Missing
[137]
HuH.7 IFNB1
Missing
[138]
SNU475 IFNB1
Missing
[139]
THLE IFNB1
Missing
[140]
liver IFNB1
Missing