WP_LEPTIN_SIGNALING_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RPS6 40S ribosomal protein S6 [1] [2] [3] [4] [5] [6] [7]
2 RHOA Transforming protein RhoA [8] -0.55[9] -0.85[10] -0.89[11] -0.81[12] -0.13[13] -1.03[14]
3 CDC42 Cell division control protein 42 homolog [15] -0.43[16] 0.48[17] -0.79[18] -0.12[19] -0.62[20] -1.78[21]
4 RAC1 Ras-related C3 botulinum toxin substrate 1 [22] 0.00[23] -0.14[24] 0.31[25] 0.43[26] 0.64[27] -0.67[28]
5 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 [29] -0.60[30] -0.73[31] -0.38[32] -2.89[33] -1.11[34] -1.30[35]
6 CFL2 Cofilin-2 [36] -0.04[37] -1.31[38] 0.05[39] 0.38[40] -0.63[41] 0.22[42]
7 AKT1 RAC-alpha serine/threonine-protein kinase [43] 0.47[44] 0.44[45] -0.91[46] 0.36[47] 0.61[48] 0.05[49]
8 STAT3 Signal transducer and activator of transcription 3 [50] 0.94[51] -0.36[52] 0.11[53] 0.65[54] 0.16[55] 2.71[56]
9 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [57] -0.53[58] -0.67[59] -0.35[60] -0.13[61] 0.60[62] -0.89[63]
10 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [64] 0.45[65] 0.32[66] 0.92[67] -0.43[68] 0.28[69] -1.40[70]
11 BCL2L1 Bcl-2-like protein 1 [71] 2.53[72] 2.11[73] 2.81[74] -0.20[75] 0.41[76] -0.52[77]
12 IL1RN Interleukin-1 receptor antagonist protein [78] -3.26[79] -0.32[80] -8.77[81] [82] -8.09[83] -0.30[84]
13 BAX Apoptosis regulator BAX [85] 0.72[86] 0.12[87] -0.60[88] -1.19[89] -0.58[90] -3.66[91]
14 CCND1 G1/S-specific cyclin-D1 [92] 3.45[93] 1.13[94] 1.70[95] 2.29[96] 1.04[97] 1.35[98]
15 IKBKG NF-kappa-B essential modulator [99] -0.49[100] -0.16[101] -2.67[102] -0.44[103] -1.42[104] -0.30[105]
16 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [106] 0.84[107] 1.46[108] 1.15[109] 1.30[110] 2.16[111] 1.56[112]
17 GRB2 Growth factor receptor-bound protein 2 [113] 1.59[114] 1.62[115] 1.48[116] 0.96[117] 1.11[118] 0.60[119]
18 STAT1 Signal transducer and activator of transcription 1-alpha/beta [120] 0.32[121] -0.40[122] 0.44[123] 2.94[124] 0.90[125] 1.25[126]
19 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1.47[127] 1.36[128] 2.26[129] 1.62[130] 1.66[131] -0.42[132]
20 BAD Bcl2-associated agonist of cell death [133] -1.28[134] -0.95[135] -2.17[136] -0.65[137] -0.02[138] -1.12[139]
21 SHC1 SHC-transforming protein 1 [140] 1.56[141] 1.97[142] 1.78[143] 3.06[144] 2.78[145] 1.08[146]
22 RELA Transcription factor p65 [147] 0.53[148] 0.22[149] 0.09[150] 0.36[151] 0.49[152] -0.58[153]
23 RAF1 RAF proto-oncogene serine/threonine-protein kinase [154] 0.33[155] 0.93[156] 1.93[157] 0.23[158] 1.32[159] 1.40[160]
24 JAK1 Tyrosine-protein kinase JAK1 [161] 0.91[162] 0.59[163] 0.50[164] 1.04[165] 1.91[166] 1.83[167]
25 EIF4E Eukaryotic translation initiation factor 4E [168] 0.53[169] 1.55[170] 0.65[171] 0.14[172] 1.39[173] 0.47[174]
26 HRAS GTPase HRas [175] -0.61[176] -1.13[177] -2.18[178] -0.54[179] -0.52[180] -2.36[181]
27 SOCS3 Suppressor of cytokine signaling 3 [182] -3.75[183] -3.96[184] -2.51[185] -0.39[186] -1.23[187] 0.43[188]
28 MAPK1 Mitogen-activated protein kinase 1 [189] 2.10[190] 2.43[191] 2.00[192] 2.26[193] 2.14[194] 2.08[195]
29 GSK3A Glycogen synthase kinase-3 alpha [196] 1.02[197] 0.95[198] 0.78[199] 0.49[200] 1.48[201] -1.53[202]
30 PTK2 Focal adhesion kinase 1 [203] 1.13[204] 1.81[205] 1.93[206] 2.36[207] 1.79[208] 1.06[209]
31 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 [210] 1.51[211] 1.37[212] 0.63[213] 2.23[214] 1.76[215] -0.01[216]
32 MAPK14 Mitogen-activated protein kinase 14 [217] 1.87[218] 2.13[219] 1.44[220] 2.09[221] 1.80[222] 1.58[223]
33 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 [224] 0.31[225] 1.79[226] 3.04[227] 1.87[228] 2.38[229] 2.36[230]
34 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [231] -0.08[232] 0.23[233] 1.06[234] 2.48[235] 2.21[236] 3.30[237]
35 KPNA4 Importin subunit alpha-3 [238] 1.32[239] 1.54[240] 1.51[241] 1.98[242] 2.28[243] 1.52[244]
36 MAPK8 Mitogen-activated protein kinase 8 [245] -1.05[246] 0.55[247] -0.84[248] -0.49[249] -0.41[250] -0.21[251]
37 SOS1 Son of sevenless homolog 1 [252] 0.29[253] 2.02[254] 1.26[255] 1.26[256] 0.72[257] 0.84[258]
38 ELK1 ETS domain-containing protein Elk-1 [259] 0.08[260] -1.86[261] 0.29[262] 0.68[263] 1.50[264] 0.13[265]
39 ROCK1 Rho-associated protein kinase 1 [266] -0.56[267] 1.16[268] 1.67[269] 1.77[270] 1.35[271] 1.88[272]
40 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -0.14[273] 1.44[274] 1.38[275] -0.15[276] 1.33[277] 2.78[278]
41 ERBB2 Receptor tyrosine-protein kinase erbB-2 [279] 2.76[280] 1.78[281] 2.69[282] 1.67[283] 1.50[284] 0.45[285]
42 NFKB1 Nuclear factor NF-kappa-B p105 subunit [286] 1.06[287] 0.93[288] 0.46[289] 0.16[290] 1.30[291] 0.75[292]
43 LEPR Leptin receptor [293] -4.20[294] -1.34[295] 1.07[296] -0.89[297] -0.60[298] 4.53[299]
44 ACACB Acetyl-CoA carboxylase 2 [300] -0.48[301] 0.69[302] 0.55[303] -1.36[304] -0.84[305] 4.48[306]
45 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [307] 2.27[308] 2.68[309] 3.03[310] 1.12[311] 1.91[312] 0.01[313]
46 ROCK2 Rho-associated protein kinase 2 [314] 1.87[315] 3.30[316] 1.51[317] 3.05[318] 1.04[319] 2.22[320]
47 RPS6KA1 Ribosomal protein S6 kinase alpha-1 [321] [322] [323] [324] [325] [326] [327]
48 CISH Cytokine-inducible SH2-containing protein [328] -2.51[329] -2.13[330] -2.19[331] -2.23[332] -3.45[333] 1.40[334]
49 MAPK3 Mitogen-activated protein kinase 3 [335] 2.24[336] 2.48[337] 2.26[338] 0.83[339] 1.08[340] -0.74[341]
50 GSK3B Glycogen synthase kinase-3 beta [342] 1.66[343] 1.49[344] 1.80[345] 2.23[346] 2.28[347] 1.46[348]
51 STAT5B Signal transducer and activator of transcription 5B [349] 1.75[350] 1.57[351] 2.01[352] 1.96[353] 1.33[354] 1.92[355]
52 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [356] 1.30[357] 2.71[358] 2.41[359] 1.06[360] 2.10[361] 1.81[362]
53 SRC Proto-oncogene tyrosine-protein kinase Src [363] 3.42[364] 3.60[365] 2.33[366] 2.81[367] 2.22[368] -0.55[369]
54 SOCS2 Suppressor of cytokine signaling 2 [370] -0.41[371] -2.76[372] -4.78[373] 1.07[374] -4.43[375] 1.95[376]
55 SP1 Transcription factor Sp1 [377] 2.21[378] 2.65[379] 3.45[380] 3.08[381] 2.99[382] 2.45[383]
56 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.88[384] 3.70[385] 2.76[386] 3.23[387] 2.95[388] 0.64[389]
57 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [390] 0.91[391] 1.17[392] 1.01[393] 0.67[394] 0.99[395] 1.48[396]
58 SH2B1 SH2B adapter protein 1 [397] 1.54[398] 2.45[399] 1.85[400] 0.73[401] 1.65[402] 0.39[403]
59 MTOR Serine/threonine-protein kinase mTOR [404] 2.93[405] 4.13[406] 3.44[407] 3.09[408] 3.40[409] 3.75[410]
60 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B [411] 0.84[412] 2.00[413] 1.98[414] -0.97[415] -1.18[416] 3.17[417]
61 RPS6KB1 Ribosomal protein S6 kinase beta-1 [418] [419] [420] [421] [422] [423] [424]
62 IL1B Interleukin-1 beta [425] -8.30[426] -7.98[427] -3.92[428] -3.18[429] 2.64[430] -4.90[431]
63 IRS1 Insulin receptor substrate 1 [432] 2.48[433] 2.12[434] 3.28[435] 2.12[436] 1.93[437] 2.41[438]
64 ACACA Acetyl-CoA carboxylase 1 [439] 2.85[440] 3.38[441] 4.03[442] 2.99[443] 2.41[444] 3.65[445]
65 FYN Tyrosine-protein kinase Fyn [446] 1.34[447] -7.07[448] 1.23[449] 1.88[450] 3.64[451] 1.27[452]
66 NCOA1 Nuclear receptor coactivator 1 [453] 0.86[454] 1.62[455] 1.55[456] 2.20[457] 1.88[458] 2.95[459]
67 CREB1 Cyclic AMP-responsive element-binding protein 1 [460] 2.12[461] 3.47[462] 3.69[463] 2.95[464] 3.12[465] 2.64[466]
68 FOXO1 Forkhead box protein O1 [467] 2.09[468] 1.95[469] 1.82[470] 1.59[471] 3.83[472] 3.39[473]
69 ESR1 Estrogen receptor [474] -6.91[475] [476] -5.46[477] -3.76[478] -5.79[479] 2.70[480]
70 SOCS7 Suppressor of cytokine signaling 7 [481] 3.54[482] 3.32[483] 3.66[484] 2.83[485] 2.78[486] 2.22[487]
71 PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 -0.89[488] -6.44[489] 0.74[490] -2.32[491] -0.94[492] 3.02[493]
72 JAK2 Tyrosine-protein kinase JAK2 [494] 0.62[495] 0.81[496] 0.10[497] 1.17[498] 2.00[499] 3.00[500]
73 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 [501] 3.43[502] 4.07[503] 3.83[504] 3.45[505] 1.72[506] 2.15[507]
74 REL Proto-oncogene c-Rel [508] -0.12[509] 1.84[510] 1.51[511] 0.56[512] 0.94[513] 2.64[514]
75 NOS3 Nitric oxide synthase, endothelial [515] 5.16[516] 2.46[517] 1.66[518] 0.47[519] 2.03[520] 3.07[521]
76 LEP Leptin [522] -0.93[523] 0.24[524] -0.57[525] -0.44[526] -1.54[527] 2.60[528]
[1]
ref_hepatocyte RPS6
Mean 819
Standard deviation 2.5e+02
Values 9e+02 7.2e+02 1.2e+03 6.5e+02 6.1e+02
[2]
HepG2 RPS6
Missing
[3]
HepG2.C3A RPS6
Missing
[4]
HuH.7 RPS6
Missing
[5]
SNU475 RPS6
Missing
[6]
THLE RPS6
Missing
[7]
liver RPS6
Missing
[8]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 1.4e+02 79 75 2.2e+02 3.8e+02
[9]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 1.8e+02 2.3e+02
[10]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[11]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[12]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.2e+02 1.5e+02
[13]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[14]
liver RHOA
Mean 101
Standard deviation 59
Values 46 54 1.6e+02 1.4e+02
[15]
ref_hepatocyte CDC42
Mean 121
Standard deviation 1e+02
Values 75 46 45 1.6e+02 2.8e+02
[16]
HepG2 CDC42
Mean 150
Standard deviation 13
Values 1.6e+02 1.4e+02
[17]
HepG2.C3A CDC42
Mean 220
Standard deviation 55
Values 2.6e+02 1.8e+02
[18]
HuH.7 CDC42
Mean 105
Standard deviation 19
Values 1.1e+02 83 1.2e+02
[19]
SNU475 CDC42
Mean 153
Standard deviation 20
Values 1.4e+02 1.7e+02
[20]
THLE CDC42
Mean 104
Standard deviation 15
Values 93 1.1e+02
[21]
liver CDC42
Mean 40.5
Standard deviation 9.1
Values 28 43 42 49
[22]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 81 47 45 28 59
[23]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 86 89
[24]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 57 67
[25]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[26]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 1e+02 89
[27]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[28]
liver RAC1
Mean 37.8
Standard deviation 32
Values 9.5 12 63 67
[29]
ref_hepatocyte EIF4EBP1
Mean 48.7
Standard deviation 38
Values 90 20 87 11 35
[30]
HepG2 EIF4EBP1
Mean 54.1
Standard deviation 26
Values 36 72
[31]
HepG2.C3A EIF4EBP1
Mean 38.6
Standard deviation 15
Values 28 49
[32]
HuH.7 EIF4EBP1
Mean 56.5
Standard deviation 22
Values 73 32 64
[33]
SNU475 EIF4EBP1
Mean 9.08
Standard deviation 1.3
Values 10 8.2
[34]
THLE EIF4EBP1
Mean 29.8
Standard deviation 5
Values 33 26
[35]
liver EIF4EBP1
Mean 22.9
Standard deviation 28
Values 4.4 3.1 62 22
[36]
ref_hepatocyte CFL2
Mean 37.6
Standard deviation 25
Values 32 21 10 70 55
[37]
HepG2 CFL2
Mean 61.5
Standard deviation 16
Values 73 51
[38]
HepG2.C3A CFL2
Mean 19.8
Standard deviation 4.7
Values 23 16
[39]
HuH.7 CFL2
Mean 58.7
Standard deviation 2.5
Values 58 62 57
[40]
SNU475 CFL2
Mean 67.6
Standard deviation 22
Values 52 83
[41]
THLE CFL2
Mean 32.2
Standard deviation 3.2
Values 30 35
[42]
liver CFL2
Mean 50.7
Standard deviation 19
Values 30 40 61 72
[43]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[44]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[45]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[46]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[47]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[48]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[49]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[50]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[51]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[52]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[53]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[54]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[55]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[56]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[57]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 32 27 15 27 39
[58]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 30 35
[59]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[60]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 40 27 33
[61]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 39 32
[62]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[63]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 12 11 28 18
[64]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[65]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[66]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[67]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[68]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[69]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[70]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[71]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 34 16 23 16 44
[72]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 2.2e+02 3e+02
[73]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[74]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.2e+02 2.1e+02 3.1e+02
[75]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 35 29
[76]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[77]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 14 9.8 31 31
[78]
ref_hepatocyte IL1RN
Mean 25.6
Standard deviation 27
Values 54 13 55 3.9 2.3
[79]
HepG2 IL1RN
Mean 4.5
Standard deviation 1.5
Values 5.6 3.4
[80]
HepG2.C3A IL1RN
Mean 26.9
Standard deviation 9.3
Values 20 33
[81]
HuH.7 IL1RN
Mean 0.0887
Standard deviation 0.12
Values 0.019 0.23 0.016
[82]
SNU475 IL1RN
Mean 0
Standard deviation 0
Values 0 0
[83]
THLE IL1RN
Mean 0.124
Standard deviation 0.05
Values 0.089 0.16
[84]
liver IL1RN
Mean 24.1
Standard deviation 32
Values 3.7 3 70 19
[85]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 34 11 27 30 21
[86]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 58 80
[87]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 33 38
[88]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 34 14 26
[89]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 16 14
[90]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[91]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 1.4 2.5 2.3 2.9
[92]
ref_hepatocyte CCND1
Mean 23
Standard deviation 14
Values 19 12 11 44 28
[93]
HepG2 CCND1
Mean 421
Standard deviation 48
Values 3.9e+02 4.5e+02
[94]
HepG2.C3A CCND1
Mean 66.1
Standard deviation 12
Values 74 58
[95]
HuH.7 CCND1
Mean 113
Standard deviation 31
Values 1.2e+02 79 1.4e+02
[96]
SNU475 CCND1
Mean 155
Standard deviation 66
Values 2e+02 1.1e+02
[97]
THLE CCND1
Mean 62.5
Standard deviation 6.4
Values 67 58
[98]
liver CCND1
Mean 67.8
Standard deviation 49
Values 25 1.1e+02 26 1.1e+02
[99]
ref_hepatocyte IKBKG
Mean 22.7
Standard deviation 14
Values 37 10 24 7.4 36
[100]
HepG2 IKBKG
Mean 27.1
Standard deviation 5.7
Values 23 31
[101]
HepG2.C3A IKBKG
Mean 26.7
Standard deviation 4
Values 24 30
[102]
HuH.7 IKBKG
Mean 5.4
Standard deviation 1.3
Values 6.7 4.1 5.4
[103]
SNU475 IKBKG
Mean 23.2
Standard deviation 3.5
Values 26 21
[104]
THLE IKBKG
Mean 11.2
Standard deviation 1
Values 10 12
[105]
liver IKBKG
Mean 21.3
Standard deviation 6.6
Values 13 22 20 29
[106]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 10 7.4 7.5 33 53
[107]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 76 58
[108]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 92 68
[109]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 61 77 86
[110]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 76 75
[111]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[112]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 80 99 60 62
[113]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 20 17 14 27 26
[114]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1.1e+02 1e+02
[115]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[116]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 93 78 89
[117]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 57 55
[118]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[119]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 22 50 50
[120]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 19 18 12 17 35
[121]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 49 36
[122]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 25 15
[123]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 40 38 47
[124]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 1.1e+02 3.2e+02
[125]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[126]
liver STAT1
Mean 55.8
Standard deviation 15
Values 38 69 49 67
[127]
ref_hepatocyte KHDRBS1
Mean 17
Standard deviation 2.6
Values 18 20 13 15 18
[128]
HepG2 KHDRBS1
Mean 79.2
Standard deviation 3.4
Values 77 82
[129]
HepG2.C3A KHDRBS1
Mean 57.2
Standard deviation 2.3
Values 56 59
[130]
HuH.7 KHDRBS1
Mean 123
Standard deviation 17
Values 1.3e+02 1e+02 1.4e+02
[131]
SNU475 KHDRBS1
Mean 72.2
Standard deviation 6.4
Values 68 77
[132]
THLE KHDRBS1
Mean 71
Standard deviation 16
Values 59 82
[133]
liver KHDRBS1
Mean 14.7
Standard deviation 4
Values 11 12 19 18
[134]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 6.7 27 28 5.4 16
[135]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 12 11
[136]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 12 10
[137]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5.5 6.4 5
[138]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 13 16
[139]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[140]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 3.7 3.7 16 12
[141]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 19 16 26 5.8 17
[142]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[143]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 93 77
[144]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 85 84 89
[145]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 1.7e+02 2.2e+02
[146]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[147]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 37 56
[148]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 35 8.1 15 9.8 12
[149]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 35 42
[150]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 20 29
[151]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 23 25 29
[152]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[153]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[154]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 5.7 4.1 19 20
[155]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 20 17 20 6 14
[156]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 36 29
[157]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 37 41
[158]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 89 93 85
[159]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 28 22
[160]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[161]
liver RAF1
Mean 47
Standard deviation 3.6
Values 46 42 51 49
[162]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 18 10 14 6.8 27
[163]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 56 40
[164]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 29 31
[165]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 29 32 36
[166]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 39 47
[167]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[168]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 62 75 54 58
[169]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 13 10 7.1 17 28
[170]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 42 31
[171]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 72 43
[172]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[173]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 22 23
[174]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[175]
liver EIF4E
Mean 24
Standard deviation 12
Values 12 16 33 36
[176]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 11 8.8 7.4 4 27
[177]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 12 14
[178]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 7.9 6
[179]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 5.6 2.4 3.6
[180]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[181]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[182]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 1.4 1.1 4.1 3.8
[183]
ref_hepatocyte SOCS3
Mean 11.2
Standard deviation 10
Values 19 10 24 1 1.5
[184]
HepG2 SOCS3
Mean 1.4
Standard deviation 0.4
Values 1.1 1.7
[185]
HepG2.C3A SOCS3
Mean 0.939
Standard deviation 0.87
Values 0.32 1.6
[186]
HuH.7 SOCS3
Mean 2.97
Standard deviation 2.7
Values 1.4 6.1 1.4
[187]
SNU475 SOCS3
Mean 11.8
Standard deviation 0.67
Values 11 12
[188]
THLE SOCS3
Mean 6.29
Standard deviation 1.1
Values 7.1 5.5
[189]
liver SOCS3
Mean 17.4
Standard deviation 5.5
Values 26 14 15 15
[190]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[191]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[192]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[193]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[194]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[195]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[196]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[197]
ref_hepatocyte GSK3A
Mean 9.38
Standard deviation 5.1
Values 17 6.4 12 7.5 3.9
[198]
HepG2 GSK3A
Mean 31.9
Standard deviation 3.3
Values 30 34
[199]
HepG2.C3A GSK3A
Mean 23.7
Standard deviation 0.26
Values 24 24
[200]
HuH.7 GSK3A
Mean 24.3
Standard deviation 3.3
Values 26 21 26
[201]
SNU475 GSK3A
Mean 18.2
Standard deviation 1.9
Values 20 17
[202]
THLE GSK3A
Mean 34.6
Standard deviation 4.3
Values 32 38
[203]
liver GSK3A
Mean 3.74
Standard deviation 0.84
Values 4.2 3.1 4.7 3
[204]
ref_hepatocyte PTK2
Mean 8.92
Standard deviation 4.8
Values 11 3.9 4.1 15 11
[205]
HepG2 PTK2
Mean 32.8
Standard deviation 5.2
Values 36 29
[206]
HepG2.C3A PTK2
Mean 40.9
Standard deviation 2.3
Values 39 43
[207]
HuH.7 PTK2
Mean 51.1
Standard deviation 2.8
Values 48 52 53
[208]
SNU475 PTK2
Mean 63.1
Standard deviation 3.5
Values 61 66
[209]
THLE PTK2
Mean 40.6
Standard deviation 3.7
Values 38 43
[210]
liver PTK2
Mean 21.5
Standard deviation 4.9
Values 24 27 19 16
[211]
ref_hepatocyte PTPN1
Mean 8.72
Standard deviation 6.8
Values 6.8 2.6 4.1 20 10
[212]
HepG2 PTPN1
Mean 41.8
Standard deviation 5
Values 45 38
[213]
HepG2.C3A PTPN1
Mean 29.5
Standard deviation 3
Values 32 27
[214]
HuH.7 PTPN1
Mean 20.4
Standard deviation 3.4
Values 19 18 24
[215]
SNU475 PTPN1
Mean 56.7
Standard deviation 1.9
Values 58 55
[216]
THLE PTPN1
Mean 39.1
Standard deviation 7.5
Values 34 44
[217]
liver PTPN1
Mean 10
Standard deviation 0.98
Values 8.6 10 11 11
[218]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[219]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[220]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[221]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[222]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[223]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[224]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[225]
ref_hepatocyte PRKAA1
Mean 8.04
Standard deviation 3.4
Values 6.1 14 7.2 5.4 7.6
[226]
HepG2 PRKAA1
Mean 16.8
Standard deviation 2.1
Values 18 15
[227]
HepG2.C3A PRKAA1
Mean 36.3
Standard deviation 5.5
Values 40 32
[228]
HuH.7 PRKAA1
Mean 99.5
Standard deviation 14
Values 84 1e+02 1.1e+02
[229]
SNU475 PRKAA1
Mean 40.7
Standard deviation 4.8
Values 37 44
[230]
THLE PRKAA1
Mean 55.1
Standard deviation 6.9
Values 60 50
[231]
liver PRKAA1
Mean 47.6
Standard deviation 7.3
Values 47 58 40 45
[232]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.2 14 8.1 4.1 7.4
[233]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 14 9.8
[234]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 13 9.6
[235]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 15 32 23
[236]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 35 80
[237]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[238]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1.4e+02 1e+02 64 32
[239]
ref_hepatocyte KPNA4
Mean 7.15
Standard deviation 4.7
Values 11 3.3 4.2 3.9 13
[240]
HepG2 KPNA4
Mean 30.1
Standard deviation 2.1
Values 32 29
[241]
HepG2.C3A KPNA4
Mean 27.3
Standard deviation 1.7
Values 26 28
[242]
HuH.7 KPNA4
Mean 30.8
Standard deviation 1.9
Values 29 31 33
[243]
SNU475 KPNA4
Mean 38.8
Standard deviation 3.2
Values 41 37
[244]
THLE KPNA4
Mean 46
Standard deviation 2.3
Values 44 48
[245]
liver KPNA4
Mean 23.6
Standard deviation 5.6
Values 25 25 29 16
[246]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[247]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[248]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[249]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[250]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[251]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[252]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[253]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 2.2 1.5 1.3 27 1.9
[254]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 19 9.4
[255]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 33 39
[256]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 15 37 22
[257]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 20 25
[258]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[259]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 16 18 13 9.3
[260]
ref_hepatocyte ELK1
Mean 6.81
Standard deviation 3.9
Values 7.5 4.4 8.5 1.7 12
[261]
HepG2 ELK1
Mean 12.1
Standard deviation 1.5
Values 11 13
[262]
HepG2.C3A ELK1
Mean 2.45
Standard deviation 0.82
Values 1.9 3
[263]
HuH.7 ELK1
Mean 12.6
Standard deviation 1.8
Values 13 11 14
[264]
SNU475 ELK1
Mean 15.1
Standard deviation 0.2
Values 15 15
[265]
THLE ELK1
Mean 25.4
Standard deviation 3.5
Values 23 28
[266]
liver ELK1
Mean 8.61
Standard deviation 2.4
Values 7.1 6 10 11
[267]
ref_hepatocyte ROCK1
Mean 6.73
Standard deviation 4.9
Values 3.6 3.9 2.5 9.7 14
[268]
HepG2 ROCK1
Mean 7.68
Standard deviation 2.4
Values 9.4 6
[269]
HepG2.C3A ROCK1
Mean 19.7
Standard deviation 1.6
Values 21 19
[270]
HuH.7 ROCK1
Mean 32.3
Standard deviation 9
Values 22 39 36
[271]
SNU475 ROCK1
Mean 31.8
Standard deviation 1.6
Values 33 31
[272]
THLE ROCK1
Mean 22.6
Standard deviation 6.2
Values 27 18
[273]
liver ROCK1
Mean 28.7
Standard deviation 3.4
Values 27 32 30 25
[274]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 5.2 11 7 4.2 5.9
[275]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 12 8.4
[276]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 21 26
[277]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[278]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 6.9 9.4
[279]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[280]
liver PTEN
Mean 52
Standard deviation 9.3
Values 53 55 61 39
[281]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 4.7 7.1 3.7 13 3.9
[282]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 81 66
[283]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 24 34
[284]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 63 55 69
[285]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 22 34
[286]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[287]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 15 8.1 7.9 9.6
[288]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[289]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[290]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[291]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[292]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[293]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[294]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[295]
ref_hepatocyte LEPR
Mean 6.17
Standard deviation 5.3
Values 2.2 11 12 0.18 5.1
[296]
HepG2 LEPR
Mean 0.566
Standard deviation 0.13
Values 0.66 0.48
[297]
HepG2.C3A LEPR
Mean 3.19
Standard deviation 0.049
Values 3.2 3.2
[298]
HuH.7 LEPR
Mean 19.5
Standard deviation 12
Values 11 33 14
[299]
SNU475 LEPR
Mean 4.59
Standard deviation 0.66
Values 4.1 5.1
[300]
THLE LEPR
Mean 5.37
Standard deviation 0.72
Values 4.9 5.9
[301]
liver LEPR
Mean 165
Standard deviation 89
Values 96 2.7e+02 86 2.1e+02
[302]
ref_hepatocyte ACACB
Mean 5.46
Standard deviation 5.5
Values 1.1 13 9.6 1.7 1.8
[303]
HepG2 ACACB
Mean 6.6
Standard deviation 0.54
Values 7 6.2
[304]
HepG2.C3A ACACB
Mean 11.5
Standard deviation 0.088
Values 12 11
[305]
HuH.7 ACACB
Mean 12.1
Standard deviation 1.9
Values 9.8 13 13
[306]
SNU475 ACACB
Mean 2.94
Standard deviation 0.034
Values 2.9 3
[307]
THLE ACACB
Mean 4.04
Standard deviation 0.24
Values 4.2 3.9
[308]
liver ACACB
Mean 141
Standard deviation 89
Values 2.6e+02 1.6e+02 90 59
[309]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 3.1 3.8 4.9 11 3.2
[310]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 41 44
[311]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 35 53
[312]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 64 55 75
[313]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 13 18
[314]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[315]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6.9 6 7.6 3.8
[316]
ref_hepatocyte ROCK2
Mean 5.22
Standard deviation 4.8
Values 3.5 1.3 0.65 11 9.5
[317]
HepG2 ROCK2
Mean 32
Standard deviation 6.2
Values 36 28
[318]
HepG2.C3A ROCK2
Mean 67.4
Standard deviation 23
Values 84 51
[319]
HuH.7 ROCK2
Mean 22.4
Standard deviation 6.9
Values 15 24 28
[320]
SNU475 ROCK2
Mean 59.5
Standard deviation 0.12
Values 60 59
[321]
THLE ROCK2
Mean 14.2
Standard deviation 4.3
Values 17 11
[322]
liver ROCK2
Mean 28.1
Standard deviation 15
Values 39 42 20 12
[323]
ref_hepatocyte RPS6KA1
Mean 4.78
Standard deviation 3.4
Values 3.5 1.5 2.9 10 5.6
[324]
HepG2 RPS6KA1
Missing
[325]
HepG2.C3A RPS6KA1
Missing
[326]
HuH.7 RPS6KA1
Missing
[327]
SNU475 RPS6KA1
Missing
[328]
THLE RPS6KA1
Missing
[329]
liver RPS6KA1
Missing
[330]
ref_hepatocyte CISH
Mean 4.68
Standard deviation 5.7
Values 3 4.7 14 0.89 0.45
[331]
HepG2 CISH
Mean 1.38
Standard deviation 0.087
Values 1.4 1.3
[332]
HepG2.C3A CISH
Mean 1.4
Standard deviation 0.43
Values 1.1 1.7
[333]
HuH.7 CISH
Mean 1.55
Standard deviation 0.25
Values 1.3 1.7 1.7
[334]
SNU475 CISH
Mean 1.37
Standard deviation 0.36
Values 1.1 1.6
[335]
THLE CISH
Mean 0.567
Standard deviation 0.027
Values 0.59 0.55
[336]
liver CISH
Mean 14.3
Standard deviation 12
Values 11 1.8 31 13
[337]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[338]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[339]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[340]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[341]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[342]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[343]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[344]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[345]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[346]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[347]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[348]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[349]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[350]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[351]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 2.3 5.6 4.6 4.1 3.3
[352]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 18 27
[353]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 13 18
[354]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 26 22 25
[355]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 19 24
[356]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[357]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 22 21 13 14
[358]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 2.3 4.1 3.4 4.2 5.7
[359]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 21 12
[360]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 43 25
[361]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 32 28 34
[362]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 12 11
[363]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[364]
liver CHUK
Mean 16
Standard deviation 3.3
Values 15 21 13 15
[365]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 2.2 1.2 0.77 9.6 4.7
[366]
HepG2 SRC
Mean 66
Standard deviation 21
Values 51 81
[367]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 45 71
[368]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 26 29 28
[369]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 33 38
[370]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[371]
liver SRC
Mean 2.9
Standard deviation 1
Values 3.2 2.5 4.1 1.7
[372]
ref_hepatocyte SOCS2
Mean 3.66
Standard deviation 2
Values 2.3 1.5 4.2 3.6 6.7
[373]
HepG2 SOCS2
Mean 4.62
Standard deviation 2.2
Values 6.2 3.1
[374]
HepG2.C3A SOCS2
Mean 0.708
Standard deviation 0.27
Values 0.9 0.52
[375]
HuH.7 SOCS2
Mean 0.201
Standard deviation 0.17
Values 0.066 0.4 0.14
[376]
SNU475 SOCS2
Mean 10.6
Standard deviation 6.9
Values 5.7 15
[377]
THLE SOCS2
Mean 0.224
Standard deviation 0.00099
Values 0.22 0.22
[378]
liver SOCS2
Mean 16.3
Standard deviation 15
Values 19 4.4 36 5.7
[379]
ref_hepatocyte SP1
Mean 3.57
Standard deviation 0.42
Values 4.3 3.6 3.5 3.2 3.3
[380]
HepG2 SP1
Mean 27.8
Standard deviation 1
Values 29 27
[381]
HepG2.C3A SP1
Mean 29.3
Standard deviation 0.25
Values 29 29
[382]
HuH.7 SP1
Mean 58.8
Standard deviation 12
Values 46 59 71
[383]
SNU475 SP1
Mean 41.7
Standard deviation 2.6
Values 40 44
[384]
THLE SP1
Mean 37.5
Standard deviation 7.4
Values 32 43
[385]
liver SP1
Mean 22.6
Standard deviation 13
Values 36 31 14 9.1
[386]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 1.7 1.2 0.91 11 2.4
[387]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 85 91
[388]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 53 67
[389]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 39 30 40
[390]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 45 47
[391]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[392]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 12 8.9 2.3 2.2
[393]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[394]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[395]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[396]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[397]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[398]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[399]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[400]
ref_hepatocyte SH2B1
Mean 3.45
Standard deviation 1.7
Values 5.6 3.2 4.8 2.4 1.2
[401]
HepG2 SH2B1
Mean 16.9
Standard deviation 1.7
Values 18 16
[402]
HepG2.C3A SH2B1
Mean 24.6
Standard deviation 4.7
Values 21 28
[403]
HuH.7 SH2B1
Mean 18.8
Standard deviation 3
Values 22 16 18
[404]
SNU475 SH2B1
Mean 7.91
Standard deviation 1.9
Values 6.6 9.2
[405]
THLE SH2B1
Mean 14.3
Standard deviation 0.094
Values 14 14
[406]
liver SH2B1
Mean 5.21
Standard deviation 0.68
Values 5.9 5.1 5.5 4.3
[407]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[408]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[409]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[410]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[411]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[412]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[413]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[414]
ref_hepatocyte PDE3B
Mean 3.29
Standard deviation 1.7
Values 1.3 5.6 3.2 4.3 2
[415]
HepG2 PDE3B
Mean 9.91
Standard deviation 5.3
Values 14 6.1
[416]
HepG2.C3A PDE3B
Mean 17.2
Standard deviation 3.4
Values 20 15
[417]
HuH.7 PDE3B
Mean 19.6
Standard deviation 4.7
Values 15 24 20
[418]
SNU475 PDE3B
Mean 2.32
Standard deviation 0.34
Values 2.1 2.6
[419]
THLE PDE3B
Mean 1.92
Standard deviation 0.37
Values 2.2 1.7
[420]
liver PDE3B
Mean 34.3
Standard deviation 15
Values 40 53 28 17
[421]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 1.9 2.1 2 5.1 4.9
[422]
HepG2 RPS6KB1
Missing
[423]
HepG2.C3A RPS6KB1
Missing
[424]
HuH.7 RPS6KB1
Missing
[425]
SNU475 RPS6KB1
Missing
[426]
THLE RPS6KB1
Missing
[427]
liver RPS6KB1
Missing
[428]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[429]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[430]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[431]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[432]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[433]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[434]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[435]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[436]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[437]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[438]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[439]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[440]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[441]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[442]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 1.7 2.7 3.2 4.3 3.2
[443]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 40 33
[444]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 32 50
[445]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 57 78 89
[446]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 23 43
[447]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[448]
liver ACACA
Mean 44
Standard deviation 21
Values 50 70 21 35
[449]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 0.23 5.5 2.6 2.2 0.039
[450]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 8.4 9.4
[451]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[452]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.5 4.8 8.9
[453]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 8.9 12
[454]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[455]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 5 4.4 8.9 5.1
[456]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.1 2.8 2.8 1.8 2
[457]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 7.4 5.4
[458]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 9 7.9
[459]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 6.6 12 9.2
[460]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 13 14
[461]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[462]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 22 23 17 13
[463]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 1.5 0.81 0.96 3.7 2.1
[464]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 15 11
[465]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 28 24
[466]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 31 36 38
[467]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[468]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[469]
liver CREB1
Mean 13
Standard deviation 3.1
Values 15 16 12 9.3
[470]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 2 2.6 1.9 0.71 1.7
[471]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 14 11
[472]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 7.9 10
[473]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 7.6 10 10
[474]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 6 8.6
[475]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[476]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 29 19 25 13
[477]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 5.3 2.2 0 0.17
[478]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.0086 0.034
[479]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[480]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.019 0.032 0.11
[481]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.25 0.06
[482]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[483]
liver ESR1
Mean 11.5
Standard deviation 7
Values 22 11 7.2 6.1
[484]
ref_hepatocyte SOCS7
Mean 1.11
Standard deviation 1.3
Values 0.7 0.22 0.25 3.4 0.95
[485]
HepG2 SOCS7
Mean 21.8
Standard deviation 3.3
Values 19 24
[486]
HepG2.C3A SOCS7
Mean 14.6
Standard deviation 3.2
Values 12 17
[487]
HuH.7 SOCS7
Mean 21.1
Standard deviation 2
Values 19 22 23
[488]
SNU475 SOCS7
Mean 10.9
Standard deviation 1.5
Values 9.8 12
[489]
THLE SOCS7
Mean 10.1
Standard deviation 0.24
Values 9.9 10
[490]
liver SOCS7
Mean 5.99
Standard deviation 4.8
Values 12 7.8 2.7 1.5
[491]
ref_hepatocyte PLCG2
Mean 0.967
Standard deviation 0.77
Values 0.46 1.6 1.9 0 0.93
[492]
HepG2 PLCG2
Mean 0.879
Standard deviation 0.82
Values 0.3 1.5
[493]
HepG2.C3A PLCG2
Mean 0.0146
Standard deviation 0.021
Values 0 0.029
[494]
HuH.7 PLCG2
Mean 2.44
Standard deviation 1.1
Values 1.8 3.7 1.9
[495]
SNU475 PLCG2
Mean 0.267
Standard deviation 0.089
Values 0.33 0.2
[496]
THLE PLCG2
Mean 0.664
Standard deviation 0.061
Values 0.62 0.71
[497]
liver PLCG2
Mean 9.03
Standard deviation 2.5
Values 8.7 10 12 5.7
[498]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 0.62 0.5 0.18 1.3 1.3
[499]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 2.9 1
[500]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 2.2 1.3
[501]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 0.9 1.6 1.2
[502]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.4 2.3
[503]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[504]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 9.8 11 4.7 2.9
[505]
ref_hepatocyte PRKAA2
Mean 0.754
Standard deviation 0.84
Values 0.23 0.24 0.1 2 1.2
[506]
HepG2 PRKAA2
Mean 13.6
Standard deviation 4
Values 16 11
[507]
HepG2.C3A PRKAA2
Mean 16.6
Standard deviation 1.4
Values 18 16
[508]
HuH.7 PRKAA2
Mean 16.2
Standard deviation 6.6
Values 9.7 23 16
[509]
SNU475 PRKAA2
Mean 11.4
Standard deviation 0.77
Values 11 12
[510]
THLE PRKAA2
Mean 3.29
Standard deviation 0.6
Values 3.7 2.9
[511]
liver PRKAA2
Mean 3.87
Standard deviation 1.2
Values 5 4 4.3 2.2
[512]
ref_hepatocyte REL
Mean 0.479
Standard deviation 0.49
Values 0.1 0.24 0.23 1.3 0.51
[513]
HepG2 REL
Mean 0.741
Standard deviation 0.46
Values 1.1 0.42
[514]
HepG2.C3A REL
Mean 2.24
Standard deviation 0.8
Values 2.8 1.7
[515]
HuH.7 REL
Mean 2.05
Standard deviation 1.2
Values 0.74 3 2.4
[516]
SNU475 REL
Mean 0.975
Standard deviation 0.12
Values 1.1 0.89
[517]
THLE REL
Mean 1.22
Standard deviation 0.23
Values 1.1 1.4
[518]
liver REL
Mean 3.46
Standard deviation 0.82
Values 4.2 4.1 2.8 2.7
[519]
ref_hepatocyte NOS3
Mean 0.251
Standard deviation 0.22
Values 0.014 0.18 0.12 0.58 0.37
[520]
HepG2 NOS3
Mean 15.1
Standard deviation 1.3
Values 16 14
[521]
HepG2.C3A NOS3
Mean 1.81
Standard deviation 0.061
Values 1.9 1.8
[522]
HuH.7 NOS3
Mean 1.2
Standard deviation 0.2
Values 1.2 1 1.4
[523]
SNU475 NOS3
Mean 0.48
Standard deviation 0.28
Values 0.28 0.68
[524]
THLE NOS3
Mean 1.36
Standard deviation 0.21
Values 1.5 1.2
[525]
liver NOS3
Mean 2.44
Standard deviation 1.3
Values 4.3 2.3 1.5 1.6
[526]
ref_hepatocyte LEP
Mean 0.0195
Standard deviation 0.035
Values 0.016 0.081 0 0 0
[527]
HepG2 LEP
Mean 0.0172
Standard deviation 2.3e-05
Values 0.017 0.017
[528]
HepG2.C3A LEP
Mean 0.0302
Standard deviation 0.012
Values 0.021 0.039
[529]
HuH.7 LEP
Mean 0.0199
Standard deviation 0.0091
Values 0.0094 0.026 0.025
[530]
SNU475 LEP
Mean 0.0198
Standard deviation 0.015
Values 0.03 0.0093
[531]
THLE LEP
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[532]
liver LEP
Mean 0.137
Standard deviation 0.14
Values 0.25 0.27 0 0.026