WP_KETONE_BODIES_SYNTHESIS_AND_DEGRADATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HMGCS2 Hydroxymethylglutaryl-CoA synthase, mitochondrial [1] -9.92[2] -8.16[3] -0.89[4] -6.87[5] -11.25[6] 0.19[7]
2 ACAT1 Acetyl-CoA acetyltransferase, mitochondrial [8] 1.04[9] 0.33[10] -0.50[11] 0.82[12] -0.25[13] -0.06[14]
3 HMGCL Hydroxymethylglutaryl-CoA lyase, mitochondrial [15] 0.60[16] 1.57[17] 1.21[18] 0.49[19] 0.03[20] -0.90[21]
4 BDH1 D-beta-hydroxybutyrate dehydrogenase, mitochondrial [22] 0.09[23] 1.27[24] -3.23[25] -5.72[26] 0.39[27] 0.45[28]
5 OXCT1 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial [29] 4.43[30] 2.92[31] 7.58[32] 7.74[33] 9.13[34] -0.05[35]
[1]
ref_hepatocyte HMGCS2
Mean 222
Standard deviation 3.3e+02
Values 3.3 7.2e+02 3.8e+02 1.4 0.38
[2]
HepG2 HMGCS2
Mean 0.0443
Standard deviation 0.046
Values 0.077 0.011
[3]
HepG2.C3A HMGCS2
Mean 0.2
Standard deviation 0.1
Values 0.13 0.27
[4]
HuH.7 HMGCS2
Mean 23.3
Standard deviation 9.9
Values 17 35 18
[5]
SNU475 HMGCS2
Mean 0.265
Standard deviation 0.27
Values 0.071 0.46
[6]
THLE HMGCS2
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[7]
liver HMGCS2
Mean 562
Standard deviation 3.1e+02
Values 3.5e+02 2.7e+02 9.5e+02 6.9e+02
[8]
ref_hepatocyte ACAT1
Mean 166
Standard deviation 1.7e+02
Values 23 3.9e+02 3.2e+02 49 47
[9]
HepG2 ACAT1
Mean 65.7
Standard deviation 6.9
Values 71 61
[10]
HepG2.C3A ACAT1
Mean 53.7
Standard deviation 16
Values 65 43
[11]
HuH.7 ACAT1
Mean 22.9
Standard deviation 6
Values 29 17 22
[12]
SNU475 ACAT1
Mean 40.9
Standard deviation 14
Values 31 51
[13]
THLE ACAT1
Mean 21.3
Standard deviation 4.8
Values 18 25
[14]
liver ACAT1
Mean 353
Standard deviation 1.8e+02
Values 1.6e+02 2.4e+02 4.7e+02 5.4e+02
[15]
ref_hepatocyte HMGCL
Mean 70.8
Standard deviation 75
Values 16 1.7e+02 1.3e+02 13 21
[16]
HepG2 HMGCL
Mean 20.8
Standard deviation 4.9
Values 17 24
[17]
HepG2.C3A HMGCL
Mean 54.2
Standard deviation 20
Values 40 68
[18]
HuH.7 HMGCL
Mean 31.8
Standard deviation 4.4
Values 37 30 29
[19]
SNU475 HMGCL
Mean 13.9
Standard deviation 6.4
Values 9.4 18
[20]
THLE HMGCL
Mean 11
Standard deviation 0.25
Values 11 11
[21]
liver HMGCL
Mean 84.2
Standard deviation 57
Values 29 42 1.3e+02 1.3e+02
[22]
ref_hepatocyte BDH1
Mean 25.6
Standard deviation 33
Values 2.5 72 50 3.3 1.2
[23]
HepG2 BDH1
Mean 5.26
Standard deviation 2
Values 6.7 3.9
[24]
HepG2.C3A BDH1
Mean 15.9
Standard deviation 1.5
Values 15 17
[25]
HuH.7 BDH1
Mean 0.531
Standard deviation 0.54
Values 0.22 1.2 0.21
[26]
SNU475 BDH1
Mean 0.0679
Standard deviation 0.0043
Values 0.071 0.065
[27]
THLE BDH1
Mean 5.14
Standard deviation 0.81
Values 4.6 5.7
[28]
liver BDH1
Mean 77.8
Standard deviation 38
Values 34 59 1.1e+02 1.1e+02
[29]
ref_hepatocyte OXCT1
Mean 0.426
Standard deviation 0.43
Values 0.46 0.31 0.078 0.13 1.1
[30]
HepG2 OXCT1
Mean 1.77
Standard deviation 0.78
Values 2.3 1.2
[31]
HepG2.C3A OXCT1
Mean 0.831
Standard deviation 0.43
Values 1.1 0.52
[32]
HuH.7 OXCT1
Mean 15.8
Standard deviation 7.7
Values 20 6.9 21
[33]
SNU475 OXCT1
Mean 12.7
Standard deviation 0.31
Values 13 13
[34]
THLE OXCT1
Mean 36.5
Standard deviation 3
Values 34 39
[35]
liver OXCT1
Mean 0.915
Standard deviation 0.1
Values 0.83 0.84 1.1 0.92