WP_KALLMANN_SYNDROME Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKT1 RAC-alpha serine/threonine-protein kinase [1] -1.07[2] -1.08[3] -2.22[4] -1.20[5] -0.97[6] -0.87[7]
2 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [8] -1.10[9] -1.20[10] -0.39[11] -1.99[12] -1.30[13] -2.33[14]
3 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [15] -0.70[16] -0.05[17] -0.16[18] -0.26[19] 0.58[20] 0.63[21]
4 GRB2 Growth factor receptor-bound protein 2 [22] 0.05[23] 0.10[24] 0.16[25] -0.60[26] -0.47[27] -0.33[28]
5 MAPK1 Mitogen-activated protein kinase 1 [29] 0.56[30] 0.92[31] 0.69[32] 0.70[33] 0.56[34] 1.15[35]
6 TMEM98 Transmembrane protein 98 [36] 0.03[37] -0.23[38] -0.58[39] -2.04[40] -1.12[41] -2.66[42]
7 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.53[43] 0.33[44] 0.46[45] -0.02[46] 0.39[47] 1.28[48]
8 FRS2 Fibroblast growth factor receptor substrate 2 [49] 0.14[50] 1.45[51] 1.89[52] 1.75[53] 1.59[54] 2.71[55]
9 CHD7 Chromodomain-helicase-DNA-binding protein 7 [56] 2.09[57] 2.33[58] 3.30[59] 1.97[60] 1.15[61] 2.66[62]
10 PLXND1 Plexin-D1 [63] 4.47[64] 3.49[65] 1.26[66] 4.98[67] 1.48[68] 3.15[69]
11 FGFR1 Fibroblast growth factor receptor 1 [70] 3.43[71] 1.96[72] 3.55[73] 3.91[74] 3.38[75] 1.03[76]
12 PRKCQ Protein kinase C theta type [77] -0.25[78] -3.59[79] [80] 0.98[81] 2.69[82] 1.46[83]
13 GNRH1 Progonadoliberin-1 [84] 0.29[85] 3.33[86] 1.90[87] 1.47[88] 1.95[89] 2.70[90]
14 OTX2 Homeobox protein OTX2 [91] [92] [93] [94] -2.62[95] [96] [97]
15 SEMA3E Semaphorin-3E [98] 0.26[99] 0.55[100] 3.15[101] 4.53[102] 1.14[103] 4.59[104]
16 ASCL1 Achaete-scute homolog 1 [105] [106] [107] -3.40[108] -4.41[109] [110] -0.78[111]
17 FGF8 Fibroblast growth factor 8 [112] -4.48[113] -3.91[114] 0.52[115] -3.07[116] [117] 2.07[118]
18 OLIG2 Oligodendrocyte transcription factor 2 [119] [120] [121] [122] [123] [124] [125]
19 ANOS1 Anosmin-1 [126] [127] [128] [129] [130] [131] [132]
20 PROK2 Prokineticin-2 [133] [134] [135] [136] [137] [138] [139]
21 NEUROG1 Neurogenin-1 [140] [141] [142] [143] [144] [145] [146]
22 PROKR2 Prokineticin receptor 2 [147] [148] [149] [150] [151] [152] [153]
23 MYRF Myelin regulatory factor [154] [155] [156] [157] [158] [159] [160]
24 SOX10 Transcription factor SOX-10 [161] [162] [163] [164] [165] [166] [167]
[1]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[2]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[3]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[4]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[5]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[6]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[7]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[8]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[9]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[10]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[11]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[12]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[13]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[14]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[15]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 10 7.4 7.5 33 53
[16]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 76 58
[17]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 92 68
[18]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 61 77 86
[19]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 76 75
[20]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[21]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 80 99 60 62
[22]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 20 17 14 27 26
[23]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1.1e+02 1e+02
[24]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[25]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 93 78 89
[26]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 57 55
[27]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[28]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 22 50 50
[29]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[30]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[31]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[32]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[33]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[34]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[35]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[36]
ref_hepatocyte TMEM98
Mean 9.69
Standard deviation 8
Values 1.3 13 5.9 22 6.4
[37]
HepG2 TMEM98
Mean 48.6
Standard deviation 8.7
Values 55 42
[38]
HepG2.C3A TMEM98
Mean 30.9
Standard deviation 7
Values 36 26
[39]
HuH.7 TMEM98
Mean 24.3
Standard deviation 4.8
Values 29 20 24
[40]
SNU475 TMEM98
Mean 9.59
Standard deviation 1.9
Values 8.3 11
[41]
THLE TMEM98
Mean 17.7
Standard deviation 4.4
Values 15 21
[42]
liver TMEM98
Mean 3.36
Standard deviation 1.6
Values 2.2 2 5.4 3.9
[43]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 0.94 1.2 2.3 2.6
[44]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 4.3 2.1
[45]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 9.6 8
[46]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 7 12 10
[47]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 6.8 8.1
[48]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[49]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 13 15 6.1 6
[50]
ref_hepatocyte FRS2
Mean 1.15
Standard deviation 0.48
Values 0.69 1.2 0.74 1.3 1.9
[51]
HepG2 FRS2
Mean 6.18
Standard deviation 3
Values 8.3 4
[52]
HepG2.C3A FRS2
Mean 11.7
Standard deviation 4
Values 15 8.9
[53]
HuH.7 FRS2
Mean 15.9
Standard deviation 4.9
Values 11 21 16
[54]
SNU475 FRS2
Mean 15.7
Standard deviation 0.35
Values 15 16
[55]
THLE FRS2
Mean 13.6
Standard deviation 0.96
Values 14 13
[56]
liver FRS2
Mean 16.5
Standard deviation 3.3
Values 15 20 18 13
[57]
ref_hepatocyte CHD7
Mean 1.1
Standard deviation 1.1
Values 1.2 0.36 0.29 2.9 0.73
[58]
HepG2 CHD7
Mean 23.1
Standard deviation 1.7
Values 24 22
[59]
HepG2.C3A CHD7
Mean 20.9
Standard deviation 0.43
Values 21 21
[60]
HuH.7 CHD7
Mean 40.7
Standard deviation 11
Values 31 38 53
[61]
SNU475 CHD7
Mean 17.7
Standard deviation 2.9
Values 20 16
[62]
THLE CHD7
Mean 9.66
Standard deviation 0.36
Values 9.4 9.9
[63]
liver CHD7
Mean 15.3
Standard deviation 4.5
Values 20 19 12 11
[64]
ref_hepatocyte PLXND1
Mean 0.852
Standard deviation 0.65
Values 0.55 0.85 0.79 1.9 0.17
[65]
HepG2 PLXND1
Mean 92.8
Standard deviation 34
Values 69 1.2e+02
[66]
HepG2.C3A PLXND1
Mean 35.9
Standard deviation 11
Values 28 44
[67]
HuH.7 PLXND1
Mean 7.66
Standard deviation 2.4
Values 7.3 5.5 10
[68]
SNU475 PLXND1
Mean 109
Standard deviation 50
Values 74 1.5e+02
[69]
THLE PLXND1
Mean 9.41
Standard deviation 0.89
Values 8.8 10
[70]
liver PLXND1
Mean 16.6
Standard deviation 10
Values 28 21 7.5 9.2
[71]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.6 0.62 0.06 1.2 0.49
[72]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 46 40
[73]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 14 9.3
[74]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[75]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 49 50
[76]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[77]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 4.3 4.2 3 3.2
[78]
ref_hepatocyte PRKCQ
Mean 0.0639
Standard deviation 0.072
Values 0 0.16 0.043 0 0.11
[79]
HepG2 PRKCQ
Mean 0.264
Standard deviation 0.11
Values 0.18 0.34
[80]
HepG2.C3A PRKCQ
Mean 0.0199
Standard deviation 0.013
Values 0.011 0.029
[81]
HuH.7 PRKCQ
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 PRKCQ
Mean 0.513
Standard deviation 0.44
Values 0.83 0.2
[83]
THLE PRKCQ
Mean 1.63
Standard deviation 0.3
Values 1.8 1.4
[84]
liver PRKCQ
Mean 0.386
Standard deviation 0.17
Values 0.54 0.3 0.19 0.51
[85]
ref_hepatocyte GNRH1
Mean 0.0524
Standard deviation 0.084
Values 0.19 0 0.069 0 0
[86]
HepG2 GNRH1
Mean 0.313
Standard deviation 0.079
Values 0.37 0.26
[87]
HepG2.C3A GNRH1
Mean 1.98
Standard deviation 0.68
Values 1.5 2.5
[88]
HuH.7 GNRH1
Mean 0.733
Standard deviation 0.24
Values 0.69 0.99 0.52
[89]
SNU475 GNRH1
Mean 0.592
Standard deviation 0.19
Values 0.72 0.46
[90]
THLE GNRH1
Mean 0.801
Standard deviation 0.31
Values 1 0.59
[91]
liver GNRH1
Mean 0.747
Standard deviation 0.54
Values 1.5 0.74 0.38 0.36
[92]
ref_hepatocyte OTX2
Mean 0.0407
Standard deviation 0.091
Values 0 0.2 0 0 0
[93]
HepG2 OTX2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A OTX2
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 OTX2
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 OTX2
Mean 0.027
Standard deviation 0.012
Values 0.035 0.019
[97]
THLE OTX2
Mean 0
Standard deviation 0
Values 0 0
[98]
liver OTX2
Mean 0
Standard deviation 0
Values 0 0 0 0
[99]
ref_hepatocyte SEMA3E
Mean 0.028
Standard deviation 0.063
Values 0 0 0 0 0.14
[100]
HepG2 SEMA3E
Mean 0.164
Standard deviation 0.044
Values 0.13 0.19
[101]
HepG2.C3A SEMA3E
Mean 0.154
Standard deviation 0.025
Values 0.17 0.14
[102]
HuH.7 SEMA3E
Mean 0.928
Standard deviation 0.6
Values 0.56 1.6 0.6
[103]
SNU475 SEMA3E
Mean 2.64
Standard deviation 0.97
Values 2 3.3
[104]
THLE SEMA3E
Mean 0.244
Standard deviation 0.13
Values 0.15 0.34
[105]
liver SEMA3E
Mean 1.48
Standard deviation 0.82
Values 1.3 0.84 2.7 1.1
[106]
ref_hepatocyte ASCL1
Mean 0.0241
Standard deviation 0.054
Values 0 0 0.12 0 0
[107]
HepG2 ASCL1
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A ASCL1
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 ASCL1
Mean 0.00859
Standard deviation 0.0082
Values 0.0094 0 0.016
[110]
SNU475 ASCL1
Mean 0.00464
Standard deviation 0.0066
Values 0 0.0093
[111]
THLE ASCL1
Mean 0
Standard deviation 0
Values 0 0
[112]
liver ASCL1
Mean 0.0309
Standard deviation 0.027
Values 0.013 0.014 0.071 0.026
[113]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0.098 0 0 0
[114]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0.0086 0
[115]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[116]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.075 0.051 0.19
[117]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.0051 0.014
[118]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[119]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.25 0.34 0.047 0.077
[120]
ref_hepatocyte OLIG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 OLIG2
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A OLIG2
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 OLIG2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[124]
SNU475 OLIG2
Mean 0.0076
Standard deviation 0.011
Values 0.015 0
[125]
THLE OLIG2
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[126]
liver OLIG2
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte ANOS1
Missing
[128]
HepG2 ANOS1
Missing
[129]
HepG2.C3A ANOS1
Missing
[130]
HuH.7 ANOS1
Missing
[131]
SNU475 ANOS1
Missing
[132]
THLE ANOS1
Missing
[133]
liver ANOS1
Missing
[134]
ref_hepatocyte PROK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 PROK2
Mean 0.0201
Standard deviation 0.028
Values 0 0.04
[136]
HepG2.C3A PROK2
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 PROK2
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 PROK2
Mean 0.00739
Standard deviation 0.0039
Values 0.01 0.0046
[139]
THLE PROK2
Mean 0
Standard deviation 0
Values 0 0
[140]
liver PROK2
Mean 0.209
Standard deviation 0.12
Values 0.33 0.043 0.26 0.21
[141]
ref_hepatocyte NEUROG1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 NEUROG1
Missing
[143]
HepG2.C3A NEUROG1
Missing
[144]
HuH.7 NEUROG1
Missing
[145]
SNU475 NEUROG1
Missing
[146]
THLE NEUROG1
Missing
[147]
liver NEUROG1
Missing
[148]
ref_hepatocyte PROKR2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 PROKR2
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A PROKR2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[151]
HuH.7 PROKR2
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 PROKR2
Mean 0
Standard deviation 0
Values 0 0
[153]
THLE PROKR2
Mean 0
Standard deviation 0
Values 0 0
[154]
liver PROKR2
Mean 0.00642
Standard deviation 0.013
Values 0 0 0 0.026
[155]
ref_hepatocyte MYRF
Missing
[156]
HepG2 MYRF
Mean 42.3
Standard deviation 5
Values 46 39
[157]
HepG2.C3A MYRF
Mean 31.5
Standard deviation 4.1
Values 29 34
[158]
HuH.7 MYRF
Mean 33.4
Standard deviation 6.2
Values 33 27 40
[159]
SNU475 MYRF
Mean 38
Standard deviation 21
Values 23 53
[160]
THLE MYRF
Mean 63.4
Standard deviation 11
Values 56 71
[161]
liver MYRF
Mean 6.25
Standard deviation 2.5
Values 6 4.2 9.8 5
[162]
ref_hepatocyte SOX10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 SOX10
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[164]
HepG2.C3A SOX10
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[165]
HuH.7 SOX10
Mean 0.0575
Standard deviation 0.025
Values 0.056 0.083 0.033
[166]
SNU475 SOX10
Mean 0.00464
Standard deviation 0.0066
Values 0 0.0093
[167]
THLE SOX10
Mean 0.0195
Standard deviation 0.0025
Values 0.018 0.021
[168]
liver SOX10
Mean 0.101
Standard deviation 0.056
Values 0.19 0.071 0.071 0.077