WP_JOUBERT_SYNDROME | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | [1] | -1.23[2] | -0.27[3] | -0.15[4] | -3.74[5] | -1.79[6] | -1.95[7] |
2 | RHOA | Transforming protein RhoA | [8] | -1.01[9] | -1.64[10] | -1.19[11] | -1.94[12] | -0.98[13] | -1.06[14] |
3 | RHEB | GTP-binding protein Rheb | [15] | -2.01[16] | -1.57[17] | -1.42[18] | -1.82[19] | -1.20[20] | -0.83[21] |
4 | CETN2 | Centrin-2 | [22] | -2.67[23] | -2.43[24] | -3.38[25] | -3.38[26] | -3.29[27] | -3.23[28] |
5 | PARP1 | Poly [ADP-ribose] polymerase 1 | [29] | 0.06[30] | -0.32[31] | 0.64[32] | -0.19[33] | -0.17[34] | -0.15[35] |
6 | RAB8A | Ras-related protein Rab-8A | [36] | -1.48[37] | -1.65[38] | -0.68[39] | -2.75[40] | -1.38[41] | -0.23[42] |
7 | FLNA | Filamin-A | [43] | 4.07[44] | 2.39[45] | -0.34[46] | 4.83[47] | 3.97[48] | 2.42[49] |
8 | DVL1 | Segment polarity protein dishevelled homolog DVL-1 | [50] | 0.74[51] | 1.06[52] | 0.16[53] | -0.65[54] | -0.11[55] | -0.50[56] |
9 | BBS5 | Bardet-Biedl syndrome 5 protein | [57] | -1.20[58] | -0.61[59] | -1.10[60] | -1.97[61] | -1.36[62] | -0.73[63] |
10 | ARL2 | ADP-ribosylation factor-like protein 2 | [64] | -0.34[65] | -0.12[66] | -2.40[67] | -1.28[68] | -0.59[69] | -1.96[70] |
11 | TMEM138 | Transmembrane protein 138 | [71] | -0.67[72] | -0.67[73] | -0.01[74] | -1.06[75] | -0.50[76] | -0.17[77] |
12 | KAT5 | Histone acetyltransferase KAT5 | [78] | -0.85[79] | -0.57[80] | -1.38[81] | -1.55[82] | -1.13[83] | -0.81[84] |
13 | UNC119 | Protein unc-119 homolog A | [85] | -0.67[86] | -0.41[87] | -0.42[88] | -1.04[89] | -0.58[90] | -0.17[91] |
14 | DVL3 | Segment polarity protein dishevelled homolog DVL-3 | [92] | 1.42[93] | 1.50[94] | 1.12[95] | 0.75[96] | 1.33[97] | 0.58[98] |
15 | PDE6D | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | -1.20[99] | -2.16[100] | -0.36[101] | -1.48[102] | -0.65[103] | -1.23[104] | |
16 | TCTN3 | Tectonic-3 | [105] | 1.36[106] | 1.63[107] | 1.81[108] | -1.00[109] | 0.58[110] | 1.09[111] |
17 | RP2 | Protein XRP2 | [112] | -0.64[113] | -0.29[114] | -0.13[115] | -0.05[116] | -0.50[117] | 0.05[118] |
18 | PCM1 | Pericentriolar material 1 protein | [119] | 0.81[120] | 2.60[121] | 2.84[122] | 0.72[123] | 1.31[124] | 3.42[125] |
19 | BBS2 | Bardet-Biedl syndrome 2 protein | [126] | 0.79[127] | 0.66[128] | -0.80[129] | -0.05[130] | 0.19[131] | 0.21[132] |
20 | MYO6 | Unconventional myosin-VI | [133] | 0.42[134] | 1.42[135] | 1.91[136] | 0.41[137] | 0.72[138] | 2.53[139] |
21 | RAD50 | DNA repair protein RAD50 | [140] | 0.09[141] | 2.08[142] | 1.46[143] | 0.55[144] | 1.55[145] | 2.47[146] |
22 | MTOR | Serine/threonine-protein kinase mTOR | [147] | 2.47[148] | 3.35[149] | 3.14[150] | 1.97[151] | 2.55[152] | 3.71[153] |
23 | B9D1 | B9 domain-containing protein 1 | [154] | -0.27[155] | -0.19[156] | -0.04[157] | -1.18[158] | -1.38[159] | -0.48[160] |
24 | TTC8 | Tetratricopeptide repeat protein 8 | [161] | -0.43[162] | 0.26[163] | -0.39[164] | 0.36[165] | 0.10[166] | 0.74[167] |
25 | ARL3 | ADP-ribosylation factor-like protein 3 | [168] | 0.60[169] | 1.38[170] | 2.00[171] | 0.02[172] | 1.14[173] | -0.17[174] |
26 | CEP104 | Centrosomal protein of 104 kDa | [175] | 1.53[176] | 1.69[177] | 1.37[178] | 0.78[179] | 1.11[180] | 2.15[181] |
27 | MKS1 | Meckel syndrome type 1 protein | [182] | 0.55[183] | 0.51[184] | 0.14[185] | -1.52[186] | -0.52[187] | -0.27[188] |
28 | OFD1 | Oral-facial-digital syndrome 1 protein | [189] | -0.53[190] | 1.08[191] | 1.23[192] | 0.08[193] | 0.30[194] | 1.56[195] |
29 | TMEM216 | Transmembrane protein 216 | [196] | 0.69[197] | 1.10[198] | 0.37[199] | -1.40[200] | -1.05[201] | -0.98[202] |
30 | PIBF1 | Progesterone-induced-blocking factor 1 | [203] | -1.63[204] | 0.44[205] | 1.60[206] | -0.50[207] | -0.09[208] | 1.31[209] |
31 | BBS4 | Bardet-Biedl syndrome 4 protein | [210] | 0.20[211] | 0.58[212] | 2.12[213] | 0.57[214] | 0.90[215] | 0.89[216] |
32 | BBS7 | Bardet-Biedl syndrome 7 protein | [217] | -0.27[218] | 0.13[219] | 0.45[220] | 0.13[221] | 1.68[222] | -0.14[223] |
33 | TCTN1 | Tectonic-1 | [224] | 0.49[225] | 0.43[226] | 0.08[227] | -0.61[228] | 0.49[229] | 0.84[230] |
34 | INVS | Inversin | [231] | 0.60[232] | 1.25[233] | 1.58[234] | 0.39[235] | 1.39[236] | 2.35[237] |
35 | NIN | Ninein | [238] | 1.47[239] | 2.02[240] | 0.87[241] | 2.05[242] | 2.30[243] | 2.44[244] |
36 | SUFU | Suppressor of fused homolog | [245] | 1.39[246] | 1.27[247] | 2.44[248] | 0.50[249] | 1.52[250] | 0.63[251] |
37 | CEP164 | Centrosomal protein of 164 kDa | [252] | 2.06[253] | 1.97[254] | 1.96[255] | 1.72[256] | 1.91[257] | 1.62[258] |
38 | CCP110 | Centriolar coiled-coil protein of 110 kDa | [259] | 0.89[260] | 1.60[261] | 0.65[262] | 0.23[263] | 1.76[264] | 1.61[265] |
39 | ARL13B | ADP-ribosylation factor-like protein 13B | [266] | -0.33[267] | 0.67[268] | 1.56[269] | 0.10[270] | 1.30[271] | 1.13[272] |
40 | RAB3IP | Rab-3A-interacting protein | [273] | 1.08[274] | 2.19[275] | 2.20[276] | 0.47[277] | 0.61[278] | 2.87[279] |
41 | INPP5E | 72 kDa inositol polyphosphate 5-phosphatase | [280] | 0.67[281] | 0.72[282] | 0.18[283] | 0.45[284] | 1.07[285] | 0.22[286] |
42 | BBS1 | Bardet-Biedl syndrome 1 protein | [287] | 1.36[288] | 0.69[289] | 2.15[290] | 0.46[291] | 0.69[292] | 1.82[293] |
43 | CSPP1 | Centrosome and spindle pole-associated protein 1 | [294] | -0.06[295] | 1.11[296] | 2.42[297] | 0.56[298] | 0.50[299] | 2.22[300] |
44 | KIAA0586 | Protein TALPID3 | [301] | 0.61[302] | 1.73[303] | 2.33[304] | 0.86[305] | 1.29[306] | 2.34[307] |
45 | CEP120 | Centrosomal protein of 120 kDa | [308] | 0.99[309] | 1.74[310] | 1.62[311] | 1.11[312] | 2.14[313] | 2.23[314] |
46 | SHH | Sonic hedgehog protein | [315] | 0.32[316] | 0.03[317] | 0.33[318] | -7.90[319] | -7.53[320] | 0.39[321] |
47 | B9D2 | B9 domain-containing protein 2 | [322] | -1.08[323] | -0.62[324] | -0.74[325] | -1.59[326] | -0.62[327] | -0.44[328] |
48 | ATM | Serine-protein kinase ATM | [329] | 2.96[330] | 4.43[331] | 4.38[332] | 3.44[333] | 3.43[334] | 5.25[335] |
49 | PCNT | Pericentrin | [336] | 2.61[337] | 2.92[338] | 2.58[339] | 2.74[340] | 3.07[341] | 4.11[342] |
50 | CC2D2A | Coiled-coil and C2 domain-containing protein 2A | [343] | 0.73[344] | 0.00[345] | 1.27[346] | 0.96[347] | 1.74[348] | 1.54[349] |
51 | CEP290 | Centrosomal protein of 290 kDa | [350] | 0.20[351] | 3.13[352] | 2.27[353] | 1.43[354] | 1.89[355] | 2.12[356] |
52 | NEK8 | Serine/threonine-protein kinase Nek8 | [357] | 0.46[358] | 1.75[359] | 1.26[360] | -0.53[361] | -0.99[362] | 1.23[363] |
53 | ANKS6 | Ankyrin repeat and SAM domain-containing protein 6 | [364] | 2.16[365] | 1.70[366] | 2.64[367] | 1.85[368] | 2.66[369] | 1.51[370] |
54 | TMEM17 | Transmembrane protein 17 | [371] | -3.43[372] | -2.90[373] | 0.90[374] | 0.27[375] | -1.07[376] | 0.24[377] |
55 | NPHP3 | Nephrocystin-3 | [378] | -0.63[379] | 0.45[380] | -0.51[381] | -0.04[382] | 0.06[383] | 1.33[384] |
56 | AHI1 | Jouberin | [385] | 0.32[386] | 2.04[387] | 2.00[388] | 2.58[389] | 2.51[390] | 3.61[391] |
57 | BBS9 | Protein PTHB1 | [392] | 1.10[393] | 0.72[394] | 1.61[395] | 0.23[396] | 0.99[397] | 2.03[398] |
58 | TCTN2 | Tectonic-2 | [399] | 1.35[400] | 0.47[401] | 1.27[402] | 0.83[403] | 0.96[404] | -0.17[405] |
59 | TMEM231 | Transmembrane protein 231 | [406] | 1.35[407] | 1.38[408] | 0.80[409] | -0.06[410] | 1.71[411] | 0.52[412] |
60 | ARMC9 | LisH domain-containing protein ARMC9 | [413] | 2.17[414] | 1.88[415] | 1.36[416] | 2.37[417] | 2.16[418] | 0.94[419] |
61 | CEP41 | Centrosomal protein of 41 kDa | [420] | 2.05[421] | 1.76[422] | 2.79[423] | 2.52[424] | 2.82[425] | 2.02[426] |
62 | RPGRIP1L | Protein fantom | [427] | 1.46[428] | 2.21[429] | 1.76[430] | 1.28[431] | 2.33[432] | 0.67[433] |
63 | MYO5A | Unconventional myosin-Va | [434] | 2.37[435] | 2.47[436] | 1.82[437] | 4.00[438] | 3.96[439] | 3.35[440] |
64 | TMEM237 | Transmembrane protein 237 | [441] | 2.98[442] | 3.49[443] | 3.67[444] | 3.36[445] | 3.85[446] | 1.65[447] |
65 | NPHP4 | Nephrocystin-4 | [448] | 3.05[449] | 3.72[450] | 3.19[451] | 0.97[452] | 2.38[453] | 2.54[454] |
66 | NPHP1 | Nephrocystin-1 | [455] | -0.06[456] | -0.46[457] | -0.86[458] | 0.28[459] | 1.05[460] | -0.96[461] |
67 | CEP97 | Centrosomal protein of 97 kDa | [462] | 0.59[463] | 1.31[464] | 2.70[465] | 1.98[466] | 3.56[467] | 2.82[468] |
68 | TMEM67 | Meckelin | [469] | 2.11[470] | 2.51[471] | 2.35[472] | 3.10[473] | 3.18[474] | 2.51[475] |
69 | PDE6B | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | [476] | -1.03[477] | -1.57[478] | -2.26[479] | 0.73[480] | -1.96[481] | 0.99[482] |
70 | PDE6A | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | [483] | 0.00[484] | 0.54[485] | 0.81[486] | 0.75[487] | 1.50[488] | 1.75[489] |
71 | ZNF423 | Zinc finger protein 423 | [490] | 1.53[491] | -4.11[492] | 0.81[493] | 0.73[494] | -2.93[495] | 3.74[496] |
72 | PDE6G | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamm | 4.73[497] | 5.74[498] | 0.89[499] | 2.26[500] | 1.09[501] | 3.34[502] | |
73 | MRE11 | Double-strand break repair protein MRE11 | [503] | [504] | [505] | [506] | [507] | [508] | [509] |
74 | CETN1 | Centrin-1 | [510] | [511] | [512] | [513] | [514] | [515] | [516] |
75 | CPLANE1 | [517] | [518] | [519] | [520] | [521] | [522] | [523] | |
76 | ARR3 | Arrestin-C | [524] | [525] | [526] | [527] | [528] | [529] | [530] |
77 | MIR6808 | [531] | [532] | [533] | [534] | [535] | [536] | [537] |