WP_INTRACELLULAR_TRAFFICKING_PROTEINS_INVOLVED_IN_CMT_NEUROPATHY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSPB1 | Heat shock protein beta-1 | [1] | -3.02[2] | -3.62[3] | -2.89[4] | -0.80[5] | -2.56[6] | -2.71[7] |
2 | RAB7A | Ras-related protein Rab-7a | [8] | -0.33[9] | -0.63[10] | -0.46[11] | -0.47[12] | 0.47[13] | -0.21[14] |
3 | RABAC1 | Prenylated Rab acceptor protein 1 | [15] | -2.09[16] | -1.57[17] | -0.89[18] | -1.73[19] | -0.89[20] | -0.18[21] |
4 | LITAF | Lipopolysaccharide-induced tumor necrosis factor-alpha factor | [22] | 1.04[23] | 0.14[24] | -1.61[25] | -0.98[26] | -1.05[27] | 0.45[28] |
5 | RAB4A | Ras-related protein Rab-4A | [29] | -0.82[30] | 0.61[31] | 0.50[32] | -1.32[33] | -1.87[34] | 0.02[35] |
6 | RAB11B | Ras-related protein Rab-11B | [36] | -0.43[37] | -0.10[38] | 0.15[39] | -0.74[40] | 0.26[41] | 0.19[42] |
7 | MFN2 | Mitofusin-2 | [43] | 1.17[44] | 2.28[45] | 1.16[46] | 1.47[47] | 1.83[48] | 2.18[49] |
8 | NDRG1 | Protein NDRG1 | [50] | 3.32[51] | 2.85[52] | 3.41[53] | 0.54[54] | 1.37[55] | 0.57[56] |
9 | RAB11A | Ras-related protein Rab-11A | [57] | 1.16[58] | 1.75[59] | 2.31[60] | 1.58[61] | 2.01[62] | 1.47[63] |
10 | DNM2 | Dynamin-2 | [64] | 2.48[65] | 1.64[66] | 1.87[67] | 1.55[68] | 2.23[69] | 1.87[70] |
11 | KIF1B | Kinesin-like protein KIF1B | [71] | 2.46[72] | 3.18[73] | 2.68[74] | 2.87[75] | 2.84[76] | 3.61[77] |
12 | RAB4B | Ras-related protein Rab-4B | [78] | [79] | [80] | [81] | [82] | [83] | [84] |
13 | HSPB8 | Heat shock protein beta-8 | [85] | -0.66[86] | -3.97[87] | -4.48[88] | 1.57[89] | 1.65[90] | -2.56[91] |
14 | MPZ | Myelin protein P0 | [92] | 0.92[93] | 2.25[94] | -7.51[95] | 0.39[96] | -1.74[97] | -1.07[98] |
15 | LRSAM1 | E3 ubiquitin-protein ligase LRSAM1 | [99] | 1.37[100] | 1.51[101] | 1.55[102] | 1.21[103] | 0.95[104] | 1.71[105] |
16 | MTMR2 | Myotubularin-related protein 2 | [106] | 2.23[107] | 3.14[108] | 1.30[109] | 3.43[110] | 3.77[111] | 1.56[112] |
17 | FIG4 | Polyphosphoinositide phosphatase | [113] | 1.12[114] | 1.54[115] | 1.48[116] | 1.67[117] | 1.96[118] | 2.04[119] |
18 | FGD4 | FYVE, RhoGEF and PH domain-containing protein 4 | [120] | -0.19[121] | 2.16[122] | 1.60[123] | 1.36[124] | 2.22[125] | 4.40[126] |
19 | RAB3B | Ras-related protein Rab-3B | [127] | 3.40[128] | 1.89[129] | 3.23[130] | 1.13[131] | 3.96[132] | 1.14[133] |
20 | SBF2 | Myotubularin-related protein 13 | [134] | 2.98[135] | 3.35[136] | 3.88[137] | 3.47[138] | 2.58[139] | 4.65[140] |
21 | GDAP1 | Ganglioside-induced differentiation-associated protein 1 | [141] | 2.14[142] | 1.25[143] | -0.33[144] | 2.81[145] | 2.40[146] | 2.16[147] |
22 | PMP22 | Peripheral myelin protein 22 | [148] | 1.14[149] | 0.26[150] | 0.98[151] | 3.87[152] | 4.92[153] | 2.79[154] |
23 | RAB3A | Ras-related protein Rab-3A | [155] | 0.39[156] | -0.45[157] | 1.65[158] | -0.21[159] | 0.39[160] | -0.12[161] |
24 | EGR2 | E3 SUMO-protein ligase EGR2 | [162] | -1.26[163] | -3.17[164] | -3.60[165] | -1.03[166] | -0.35[167] | 0.61[168] |
25 | RAB25 | Ras-related protein Rab-25 | [169] | -0.68[170] | 5.77[171] | -3.15[172] | -5.64[173] | -6.17[174] | 1.31[175] |
26 | SH3TC2 | SH3 domain and tetratricopeptide repeat-containing protein 2 | [176] | 4.80[177] | -3.50[178] | [179] | 5.95[180] | 3.91[181] | 4.61[182] |
27 | NEFL | Neurofilament light polypeptide | [183] | -1.54[184] | [185] | 0.46[186] | 10.26[187] | 3.33[188] | [189] |