WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NFKBIA NF-kappa-B inhibitor alpha [1] -1.02[2] -2.87[3] -3.12[4] -3.21[5] -1.65[6] -1.09[7]
2 FOS Proto-oncogene c-Fos [8] -5.98[9] -4.77[10] -5.31[11] -5.86[12] -5.11[13] -1.26[14]
3 MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 [15] -1.19[16] -0.94[17] -1.92[18] -1.52[19] -1.97[20] -1.39[21]
4 MYC Myc proto-oncogene protein [22] 0.46[23] 0.07[24] -1.83[25] -2.48[26] -0.43[27] -1.95[28]
5 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 [29] 0.22[30] -0.36[31] -0.12[32] -0.86[33] -0.18[34] -0.93[35]
6 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [36] -0.90[37] -1.28[38] -0.57[39] -0.24[40] -0.04[41] -1.15[42]
7 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [43] 0.09[44] -0.29[45] 0.70[46] -0.54[47] -0.36[48] -1.66[49]
8 IRAK1 Interleukin-1 receptor-associated kinase 1 [50] 1.45[51] 0.79[52] -0.11[53] 1.10[54] 1.16[55] -0.64[56]
9 SAFB Scaffold attachment factor B1 [57] -0.08[58] -0.26[59] 0.31[60] -0.35[61] -0.32[62] -1.06[63]
10 TOLLIP Toll-interacting protein [64] -0.24[65] -0.40[66] -0.28[67] -0.72[68] -1.88[69] 1.19[70]
11 IL1R1 Interleukin-1 receptor type 1 [71] -0.54[72] -0.95[73] -1.47[74] -0.52[75] 1.84[76] 0.82[77]
12 RELA Transcription factor p65 [78] 0.17[79] -0.39[80] -0.13[81] 0.25[82] -0.16[83] -0.84[84]
13 EIF4E Eukaryotic translation initiation factor 4E [85] 0.17[86] 0.95[87] 0.44[88] 0.03[89] 0.75[90] 0.21[91]
14 NFKBIB NF-kappa-B inhibitor beta [92] -1.13[93] -1.36[94] -0.90[95] -1.51[96] -1.48[97] -1.68[98]
15 MAPKAPK2 MAP kinase-activated protein kinase 2 [99] 0.49[100] -0.53[101] 0.01[102] 1.70[103] 0.60[104] -0.90[105]
16 MYD88 Myeloid differentiation primary response protein MyD88 [106] -0.15[107] -0.15[108] -0.59[109] -0.73[110] -0.75[111] 0.84[112]
17 IRF7 Interferon regulatory factor 7 [113] -9.20[114] -8.26[115] -7.03[116] -2.84[117] -3.41[118] -0.03[119]
18 IL1RAP Interleukin-1 receptor accessory protein [120] -1.47[121] 0.71[122] 0.47[123] -1.16[124] -0.39[125] 2.23[126]
19 MAPK1 Mitogen-activated protein kinase 1 [127] 1.74[128] 1.83[129] 1.78[130] 2.16[131] 1.49[132] 1.82[133]
20 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [134] 0.40[135] 0.51[136] 0.90[137] 2.01[138] 1.15[139] 0.29[140]
21 MAPK14 Mitogen-activated protein kinase 14 [141] 1.51[142] 1.52[143] 1.22[144] 1.99[145] 1.15[146] 1.33[147]
22 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 [148] -0.07[149] 0.95[150] 0.95[151] 0.80[152] 0.66[153] 0.29[154]
23 TANK TRAF family member-associated NF-kappa-B activator [155] -1.11[156] 0.82[157] 0.58[158] 0.43[159] -0.65[160] 0.58[161]
24 IRAK2 Interleukin-1 receptor-associated kinase-like 2 [162] -0.05[163] 0.00[164] -0.09[165] -2.12[166] -0.89[167] -0.98[168]
25 ATF2 Cyclic AMP-dependent transcription factor ATF-2 [169] 0.67[170] 1.67[171] 2.02[172] 1.09[173] 0.55[174] 1.07[175]
26 MAPK8 Mitogen-activated protein kinase 8 [176] -1.41[177] -0.06[178] -1.06[179] -0.60[180] -1.05[181] -0.47[182]
27 ELK1 ETS domain-containing protein Elk-1 [183] -0.28[184] -2.47[185] 0.07[186] 0.58[187] 0.85[188] -0.12[189]
28 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [190] 0.09[191] 1.98[192] 2.20[193] 0.66[194] 1.54[195] 0.87[196]
29 NFKB1 Nuclear factor NF-kappa-B p105 subunit [197] 0.70[198] 0.33[199] 0.24[200] 0.06[201] 0.65[202] 0.50[203]
30 MBP Myelin basic protein [204] -1.54[205] 0.17[206] -1.71[207] -0.47[208] -0.61[209] 0.96[210]
31 MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 [211] 0.74[212] 1.31[213] 0.64[214] 1.51[215] 0.60[216] 1.11[217]
32 MAPK9 Mitogen-activated protein kinase 9 [218] 1.26[219] 1.43[220] 1.62[221] 2.02[222] 1.16[223] 0.55[224]
33 MAPK3 Mitogen-activated protein kinase 3 [225] 1.88[226] 1.87[227] 2.04[228] 0.73[229] 0.44[230] -1.00[231]
34 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [232] 0.93[233] 2.10[234] 2.19[235] 0.96[236] 1.46[237] 1.56[238]
35 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 [239] 0.99[240] 1.09[241] 1.79[242] 0.59[243] 0.83[244] -0.71[245]
36 MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 [246] 0.40[247] -0.03[248] 0.61[249] 0.65[250] -0.06[251] 0.74[252]
37 TAB1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [253] 0.68[254] 1.27[255] 1.48[256] 0.32[257] 0.34[258] 0.27[259]
38 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [260] 0.55[261] 0.56[262] 0.79[263] 0.57[264] 0.34[265] 1.23[266]
39 MAP3K14 Mitogen-activated protein kinase kinase kinase 14 [267] -0.37[268] 0.04[269] -1.00[270] 2.38[271] 1.05[272] 0.92[273]
40 MAP3K8 Mitogen-activated protein kinase kinase kinase 8 [274] 1.78[275] 1.73[276] 1.04[277] 0.41[278] 1.42[279] 0.53[280]
41 MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 [281] 0.32[282] -2.94[283] 2.03[284] 1.32[285] -3.03[286] -1.57[287]
42 MAP3K3 Mitogen-activated protein kinase kinase kinase 3 [288] 1.65[289] 2.09[290] 1.49[291] 2.39[292] 2.33[293] 2.19[294]
43 IRAK4 Interleukin-1 receptor-associated kinase 4 [295] 0.29[296] 1.60[297] 2.00[298] 1.73[299] 1.17[300] 1.82[301]
44 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 [302] 2.68[303] 2.34[304] 2.20[305] 2.63[306] 1.20[307] 2.84[308]
45 TRAF6 TNF receptor-associated factor 6 [309] 1.12[310] 0.96[311] 1.65[312] 1.97[313] 1.11[314] 2.95[315]
46 RPS6KA5 Ribosomal protein S6 kinase alpha-5 [316] [317] [318] [319] [320] [321] [322]
47 MAPK11 Mitogen-activated protein kinase 11 [323] -0.14[324] -0.30[325] -1.06[326] 0.66[327] 2.34[328] 0.21[329]
48 IL1A Interleukin-1 alpha [330] -0.39[331] -0.85[332] -1.90[333] -0.33[334] 6.10[335] -1.54[336]
49 MAPK10 Mitogen-activated protein kinase 10 [337] -1.45[338] [339] [340] 9.21[341] 4.64[342] 7.29[343]
50 MIR718 [344] [345] [346] [347] [348] [349] [350]
[1]
ref_hepatocyte NFKBIA
Mean 84.3
Standard deviation 48
Values 1.6e+02 40 90 83 48
[2]
HepG2 NFKBIA
Mean 89.6
Standard deviation 1.2
Values 90 89
[3]
HepG2.C3A NFKBIA
Mean 23
Standard deviation 1.2
Values 22 24
[4]
HuH.7 NFKBIA
Mean 17
Standard deviation 7.2
Values 15 25 11
[5]
SNU475 NFKBIA
Mean 13.5
Standard deviation 0.67
Values 14 13
[6]
THLE NFKBIA
Mean 55.8
Standard deviation 6.4
Values 51 60
[7]
liver NFKBIA
Mean 54.5
Standard deviation 46
Values 24 19 1.2e+02 55
[8]
ref_hepatocyte FOS
Mean 40
Standard deviation 67
Values 9 27 1.6e+02 4 0.65
[9]
HepG2 FOS
Mean 1.37
Standard deviation 1
Values 0.66 2.1
[10]
HepG2.C3A FOS
Mean 2.92
Standard deviation 1.9
Values 1.6 4.3
[11]
HuH.7 FOS
Mean 1.77
Standard deviation 0.38
Values 2.2 1.6 1.5
[12]
SNU475 FOS
Mean 1.02
Standard deviation 0.13
Values 1.1 0.93
[13]
THLE FOS
Mean 2.4
Standard deviation 0.3
Values 2.2 2.6
[14]
liver FOS
Mean 23
Standard deviation 32
Values 5.7 4.8 71 10
[15]
ref_hepatocyte MAP2K3
Mean 32.7
Standard deviation 39
Values 1e+02 17 16 11 17
[16]
HepG2 MAP2K3
Mean 31
Standard deviation 5.7
Values 35 27
[17]
HepG2.C3A MAP2K3
Mean 34
Standard deviation 1.9
Values 33 35
[18]
HuH.7 MAP2K3
Mean 15.2
Standard deviation 4.8
Values 18 9.6 18
[19]
SNU475 MAP2K3
Mean 16.9
Standard deviation 1.1
Values 18 16
[20]
THLE MAP2K3
Mean 17.3
Standard deviation 3
Values 15 19
[21]
liver MAP2K3
Mean 17.2
Standard deviation 13
Values 7.1 4.9 30 26
[22]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 89 1.4 23 15 20
[23]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 52 1.3e+02
[24]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 52 73
[25]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 14 18 13
[26]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 8.9 6.9
[27]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[28]
liver MYC
Mean 10.6
Standard deviation 6
Values 5.5 5.9 18 13
[29]
ref_hepatocyte MKNK2
Mean 28.3
Standard deviation 24
Values 66 26 33 7.9 8.5
[30]
HepG2 MKNK2
Mean 71.5
Standard deviation 19
Values 58 85
[31]
HepG2.C3A MKNK2
Mean 44
Standard deviation 12
Values 36 52
[32]
HuH.7 MKNK2
Mean 45.9
Standard deviation 9.7
Values 39 57 42
[33]
SNU475 MKNK2
Mean 23.2
Standard deviation 4.1
Values 20 26
[34]
THLE MKNK2
Mean 51.9
Standard deviation 8.4
Values 58 46
[35]
liver MKNK2
Mean 20.4
Standard deviation 5.4
Values 24 16 26 16
[36]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 32 27 15 27 39
[37]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 30 35
[38]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[39]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 40 27 33
[40]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 39 32
[41]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[42]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 12 11 28 18
[43]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[44]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[45]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[46]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[47]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[48]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[49]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[50]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 38 5 16 18 30
[51]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 97 1.5e+02
[52]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 75 72
[53]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 34 31 40
[54]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 78 58
[55]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[56]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 24 19 17 15
[57]
ref_hepatocyte SAFB
Mean 20.7
Standard deviation 12
Values 20 7.6 12 37 27
[58]
HepG2 SAFB
Mean 42.5
Standard deviation 0.54
Values 42 43
[59]
HepG2.C3A SAFB
Mean 34.5
Standard deviation 5.6
Values 31 38
[60]
HuH.7 SAFB
Mean 45
Standard deviation 9.2
Values 49 34 51
[61]
SNU475 SAFB
Mean 24.2
Standard deviation 2
Values 26 23
[62]
THLE SAFB
Mean 34.3
Standard deviation 5.2
Values 31 38
[63]
liver SAFB
Mean 13.7
Standard deviation 1.5
Values 15 14 12 14
[64]
ref_hepatocyte TOLLIP
Mean 18.6
Standard deviation 8.7
Values 14 30 25 11 13
[65]
HepG2 TOLLIP
Mean 34
Standard deviation 0.071
Values 34 34
[66]
HepG2.C3A TOLLIP
Mean 28
Standard deviation 5.6
Values 24 32
[67]
HuH.7 TOLLIP
Mean 26.9
Standard deviation 1.7
Values 27 28 25
[68]
SNU475 TOLLIP
Mean 16.7
Standard deviation 4.2
Values 14 20
[69]
THLE TOLLIP
Mean 10.5
Standard deviation 2.7
Values 8.5 12
[70]
liver TOLLIP
Mean 58.3
Standard deviation 25
Values 45 30 83 75
[71]
ref_hepatocyte IL1R1
Mean 16.2
Standard deviation 7
Values 12 18 17 26 7.8
[72]
HepG2 IL1R1
Mean 24.1
Standard deviation 14
Values 34 14
[73]
HepG2.C3A IL1R1
Mean 16.7
Standard deviation 3.1
Values 19 14
[74]
HuH.7 IL1R1
Mean 10.2
Standard deviation 4
Values 7.6 15 8.3
[75]
SNU475 IL1R1
Mean 16.8
Standard deviation 1.1
Values 18 16
[76]
THLE IL1R1
Mean 120
Standard deviation 0.57
Values 1.2e+02 1.2e+02
[77]
liver IL1R1
Mean 39.3
Standard deviation 8.9
Values 42 47 27 41
[78]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 35 8.1 15 9.8 12
[79]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 35 42
[80]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 20 29
[81]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 23 25 29
[82]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[83]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[84]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 5.7 4.1 19 20
[85]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 13 10 7.1 17 28
[86]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 42 31
[87]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 72 43
[88]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[89]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 22 23
[90]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[91]
liver EIF4E
Mean 24
Standard deviation 12
Values 12 16 33 36
[92]
ref_hepatocyte NFKBIB
Mean 13.2
Standard deviation 9.2
Values 27 12 17 3.7 6.2
[93]
HepG2 NFKBIB
Mean 13
Standard deviation 3.4
Values 11 15
[94]
HepG2.C3A NFKBIB
Mean 10.3
Standard deviation 1.5
Values 9.2 11
[95]
HuH.7 NFKBIB
Mean 12.4
Standard deviation 1.7
Values 14 12 11
[96]
SNU475 NFKBIB
Mean 6.88
Standard deviation 1.6
Values 8 5.7
[97]
THLE NFKBIB
Mean 9.79
Standard deviation 0.9
Values 9.1 10
[98]
liver NFKBIB
Mean 5.65
Standard deviation 1
Values 6.8 4.3 6.1 5.5
[99]
ref_hepatocyte MAPKAPK2
Mean 13.1
Standard deviation 7.6
Values 24 8.7 17 5.2 10
[100]
HepG2 MAPKAPK2
Mean 39.7
Standard deviation 1.4
Values 39 41
[101]
HepG2.C3A MAPKAPK2
Mean 18.1
Standard deviation 4.5
Values 15 21
[102]
HuH.7 MAPKAPK2
Mean 23.2
Standard deviation 2.9
Values 25 20 25
[103]
SNU475 MAPKAPK2
Mean 63.2
Standard deviation 4
Values 60 66
[104]
THLE MAPKAPK2
Mean 40.9
Standard deviation 0.33
Values 41 41
[105]
liver MAPKAPK2
Mean 9.67
Standard deviation 2.5
Values 11 11 10 6
[106]
ref_hepatocyte MYD88
Mean 12.3
Standard deviation 6.2
Values 14 17 19 5.4 6
[107]
HepG2 MYD88
Mean 23.8
Standard deviation 12
Values 32 16
[108]
HepG2.C3A MYD88
Mean 22.1
Standard deviation 5.1
Values 26 18
[109]
HuH.7 MYD88
Mean 14.3
Standard deviation 1.1
Values 15 13 15
[110]
SNU475 MYD88
Mean 11
Standard deviation 1.1
Values 10 12
[111]
THLE MYD88
Mean 15.1
Standard deviation 1.7
Values 14 16
[112]
liver MYD88
Mean 30.3
Standard deviation 21
Values 14 9.8 47 51
[113]
ref_hepatocyte IRF7
Mean 11.7
Standard deviation 10
Values 11 24 20 0 3.4
[114]
HepG2 IRF7
Mean 0.0429
Standard deviation 0.012
Values 0.051 0.034
[115]
HepG2.C3A IRF7
Mean 0.0764
Standard deviation 0.0019
Values 0.075 0.078
[116]
HuH.7 IRF7
Mean 0.158
Standard deviation 0.13
Values 0.028 0.29 0.16
[117]
SNU475 IRF7
Mean 2.42
Standard deviation 0.34
Values 2.7 2.2
[118]
THLE IRF7
Mean 2.27
Standard deviation 0.44
Values 2 2.6
[119]
liver IRF7
Mean 15.8
Standard deviation 4.5
Values 18 9.6 16 20
[120]
ref_hepatocyte IL1RAP
Mean 11.2
Standard deviation 11
Values 2.4 29 16 5 3.6
[121]
HepG2 IL1RAP
Mean 8.79
Standard deviation 4.5
Values 12 5.6
[122]
HepG2.C3A IL1RAP
Mean 36.6
Standard deviation 11
Values 29 45
[123]
HuH.7 IL1RAP
Mean 27.4
Standard deviation 12
Values 18 41 23
[124]
SNU475 IL1RAP
Mean 7.46
Standard deviation 1.6
Values 8.6 6.3
[125]
THLE IL1RAP
Mean 17.8
Standard deviation 1.2
Values 17 19
[126]
liver IL1RAP
Mean 72.8
Standard deviation 24
Values 1.1e+02 68 58 57
[127]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[128]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[129]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[130]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[131]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[132]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[133]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[134]
ref_hepatocyte TAB2
Mean 9.62
Standard deviation 3.5
Values 16 7.8 8.4 7.9 8.1
[135]
HepG2 TAB2
Mean 27.4
Standard deviation 8.1
Values 33 22
[136]
HepG2.C3A TAB2
Mean 27.3
Standard deviation 2.5
Values 26 29
[137]
HuH.7 TAB2
Mean 31.5
Standard deviation 8.5
Values 25 41 28
[138]
SNU475 TAB2
Mean 57.4
Standard deviation 2.2
Values 56 59
[139]
THLE TAB2
Mean 44.2
Standard deviation 0.52
Values 44 45
[140]
liver TAB2
Mean 16.2
Standard deviation 4.7
Values 19 15 21 10
[141]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[142]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[143]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[144]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[145]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[146]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[147]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[148]
ref_hepatocyte MAP3K7
Mean 8.64
Standard deviation 6.6
Values 4.6 3.6 4 18 13
[149]
HepG2 MAP3K7
Mean 17.8
Standard deviation 6.7
Values 23 13
[150]
HepG2.C3A MAP3K7
Mean 33.3
Standard deviation 3
Values 35 31
[151]
HuH.7 MAP3K7
Mean 29.2
Standard deviation 2.3
Values 30 27 31
[152]
SNU475 MAP3K7
Mean 22.3
Standard deviation 2.2
Values 21 24
[153]
THLE MAP3K7
Mean 28.3
Standard deviation 1.5
Values 29 27
[154]
liver MAP3K7
Mean 14.6
Standard deviation 1.8
Values 12 16 14 16
[155]
ref_hepatocyte TANK
Mean 8.63
Standard deviation 3.4
Values 5.3 14 10 7.4 6.5
[156]
HepG2 TANK
Mean 8.65
Standard deviation 2.2
Values 10 7.1
[157]
HepG2.C3A TANK
Mean 30.5
Standard deviation 0.31
Values 30 31
[158]
HuH.7 TANK
Mean 22.6
Standard deviation 1.7
Values 25 21 22
[159]
SNU475 TANK
Mean 17.3
Standard deviation 2.1
Values 16 19
[160]
THLE TANK
Mean 11.4
Standard deviation 0.54
Values 12 11
[161]
liver TANK
Mean 17.8
Standard deviation 10
Values 9.7 10 32 20
[162]
ref_hepatocyte IRAK2
Mean 8.12
Standard deviation 8.7
Values 22 1.9 2.3 2.6 12
[163]
HepG2 IRAK2
Mean 17
Standard deviation 8.7
Values 11 23
[164]
HepG2.C3A IRAK2
Mean 16.3
Standard deviation 5.4
Values 12 20
[165]
HuH.7 IRAK2
Mean 13.4
Standard deviation 4.3
Values 11 18 10
[166]
SNU475 IRAK2
Mean 2.77
Standard deviation 1.6
Values 3.9 1.6
[167]
THLE IRAK2
Mean 9.08
Standard deviation 2
Values 7.7 10
[168]
liver IRAK2
Mean 5.68
Standard deviation 1
Values 6.5 5.2 4.5 6.5
[169]
ref_hepatocyte ATF2
Mean 7.65
Standard deviation 3.4
Values 9.4 6.6 3.3 12 6.7
[170]
HepG2 ATF2
Mean 26.3
Standard deviation 12
Values 35 18
[171]
HepG2.C3A ATF2
Mean 48.4
Standard deviation 7.6
Values 54 43
[172]
HuH.7 ATF2
Mean 54.5
Standard deviation 4.5
Values 50 59 55
[173]
SNU475 ATF2
Mean 24.2
Standard deviation 8.8
Values 18 30
[174]
THLE ATF2
Mean 23.1
Standard deviation 0.6
Values 24 23
[175]
liver ATF2
Mean 22
Standard deviation 3.2
Values 20 26 19 23
[176]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[177]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[178]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[179]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[180]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[181]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[182]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[183]
ref_hepatocyte ELK1
Mean 6.81
Standard deviation 3.9
Values 7.5 4.4 8.5 1.7 12
[184]
HepG2 ELK1
Mean 12.1
Standard deviation 1.5
Values 11 13
[185]
HepG2.C3A ELK1
Mean 2.45
Standard deviation 0.82
Values 1.9 3
[186]
HuH.7 ELK1
Mean 12.6
Standard deviation 1.8
Values 13 11 14
[187]
SNU475 ELK1
Mean 15.1
Standard deviation 0.2
Values 15 15
[188]
THLE ELK1
Mean 25.4
Standard deviation 3.5
Values 23 28
[189]
liver ELK1
Mean 8.61
Standard deviation 2.4
Values 7.1 6 10 11
[190]
ref_hepatocyte TAB3
Mean 6.67
Standard deviation 6.1
Values 5.5 3.1 1.9 17 5.7
[191]
HepG2 TAB3
Mean 15.3
Standard deviation 7.1
Values 20 10
[192]
HepG2.C3A TAB3
Mean 52.5
Standard deviation 9.3
Values 46 59
[193]
HuH.7 TAB3
Mean 53.9
Standard deviation 32
Values 30 90 42
[194]
SNU475 TAB3
Mean 15.6
Standard deviation 5
Values 12 19
[195]
THLE TAB3
Mean 40.2
Standard deviation 2.3
Values 42 39
[196]
liver TAB3
Mean 16.8
Standard deviation 3.6
Values 13 18 21 15
[197]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[198]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[199]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[200]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[201]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[202]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[203]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[204]
ref_hepatocyte MBP
Mean 6.31
Standard deviation 2.9
Values 9.4 5 3.3 4.4 9.4
[205]
HepG2 MBP
Mean 4.68
Standard deviation 1.6
Values 3.6 5.8
[206]
HepG2.C3A MBP
Mean 14.2
Standard deviation 3.4
Values 12 17
[207]
HuH.7 MBP
Mean 3.39
Standard deviation 0.45
Values 3 3.3 3.9
[208]
SNU475 MBP
Mean 6.75
Standard deviation 4
Values 3.9 9.6
[209]
THLE MBP
Mean 8.53
Standard deviation 0.18
Values 8.7 8.4
[210]
liver MBP
Mean 16.9
Standard deviation 2.6
Values 13 17 20 18
[211]
ref_hepatocyte MAP2K4
Mean 5.23
Standard deviation 0.4
Values 5.1 5.2 4.9 5.1 5.9
[212]
HepG2 MAP2K4
Mean 18.8
Standard deviation 5.8
Values 23 15
[213]
HepG2.C3A MAP2K4
Mean 26
Standard deviation 3.4
Values 28 24
[214]
HuH.7 MAP2K4
Mean 14.3
Standard deviation 2.4
Values 12 17 14
[215]
SNU475 MAP2K4
Mean 22.2
Standard deviation 0.79
Values 22 23
[216]
THLE MAP2K4
Mean 16.4
Standard deviation 1.6
Values 15 17
[217]
liver MAP2K4
Mean 15.6
Standard deviation 2
Values 13 17 16 17
[218]
ref_hepatocyte MAPK9
Mean 4.45
Standard deviation 2.7
Values 1.4 3.3 3.7 8.6 5.3
[219]
HepG2 MAPK9
Mean 23
Standard deviation 4.4
Values 26 20
[220]
HepG2.C3A MAPK9
Mean 24
Standard deviation 3.3
Values 26 22
[221]
HuH.7 MAPK9
Mean 24
Standard deviation 2.9
Values 25 21 26
[222]
SNU475 MAPK9
Mean 26.8
Standard deviation 2.4
Values 25 29
[223]
THLE MAPK9
Mean 20.6
Standard deviation 0.2
Values 21 21
[224]
liver MAPK9
Mean 9.01
Standard deviation 3.1
Values 11 12 7.1 5.7
[225]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[226]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[227]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[228]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[229]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[230]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[231]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[232]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 2.3 4.1 3.4 4.2 5.7
[233]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 21 12
[234]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 43 25
[235]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 32 28 34
[236]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 12 11
[237]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[238]
liver CHUK
Mean 16
Standard deviation 3.3
Values 15 21 13 15
[239]
ref_hepatocyte MAP2K7
Mean 3.82
Standard deviation 2
Values 6.2 3 5.7 2.7 1.5
[240]
HepG2 MAP2K7
Mean 16.4
Standard deviation 3.3
Values 14 19
[241]
HepG2.C3A MAP2K7
Mean 16.2
Standard deviation 4
Values 13 19
[242]
HuH.7 MAP2K7
Mean 23.1
Standard deviation 1.5
Values 23 22 24
[243]
SNU475 MAP2K7
Mean 8.53
Standard deviation 0.26
Values 8.7 8.3
[244]
THLE MAP2K7
Mean 14
Standard deviation 0.17
Values 14 14
[245]
liver MAP2K7
Mean 3.21
Standard deviation 0.87
Values 4.4 3 3.1 2.3
[246]
ref_hepatocyte MKNK1
Mean 3.72
Standard deviation 0.64
Values 3.9 3.4 3.7 3 4.7
[247]
HepG2 MKNK1
Mean 10.6
Standard deviation 2.1
Values 12 9.1
[248]
HepG2.C3A MKNK1
Mean 7.29
Standard deviation 0.2
Values 7.2 7.4
[249]
HuH.7 MKNK1
Mean 10
Standard deviation 0.97
Values 11 8.9 10
[250]
SNU475 MKNK1
Mean 8.68
Standard deviation 2.1
Values 7.2 10
[251]
THLE MKNK1
Mean 7.38
Standard deviation 0.36
Values 7.6 7.1
[252]
liver MKNK1
Mean 8.59
Standard deviation 2.1
Values 7.3 6.3 11 10
[253]
ref_hepatocyte TAB1
Mean 3.61
Standard deviation 1.3
Values 5.1 4.1 4.4 2.3 2.1
[254]
HepG2 TAB1
Mean 12.5
Standard deviation 0.3
Values 12 13
[255]
HepG2.C3A TAB1
Mean 17.4
Standard deviation 1.8
Values 16 19
[256]
HuH.7 TAB1
Mean 17.6
Standard deviation 2.2
Values 19 15 19
[257]
SNU475 TAB1
Mean 6.68
Standard deviation 1.2
Values 5.8 7.5
[258]
THLE TAB1
Mean 9.45
Standard deviation 1.6
Values 8.3 11
[259]
liver TAB1
Mean 5.99
Standard deviation 1.7
Values 5.1 4.1 7.6 7.1
[260]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[261]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[262]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[263]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[264]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[265]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[266]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[267]
ref_hepatocyte MAP3K14
Mean 1.9
Standard deviation 1.1
Values 3.6 1.1 1.7 0.92 2.2
[268]
HepG2 MAP3K14
Mean 3.19
Standard deviation 0.37
Values 2.9 3.4
[269]
HepG2.C3A MAP3K14
Mean 3.89
Standard deviation 0.18
Values 3.8 4
[270]
HuH.7 MAP3K14
Mean 1.66
Standard deviation 0.35
Values 1.8 1.9 1.3
[271]
SNU475 MAP3K14
Mean 14.7
Standard deviation 3
Values 17 13
[272]
THLE MAP3K14
Mean 8.14
Standard deviation 0.86
Values 8.8 7.5
[273]
liver MAP3K14
Mean 4.97
Standard deviation 1.7
Values 6.4 4.3 2.9 6.3
[274]
ref_hepatocyte MAP3K8
Mean 1.71
Standard deviation 2
Values 5.2 0.54 0.8 1.4 0.66
[275]
HepG2 MAP3K8
Mean 12.6
Standard deviation 0.62
Values 12 13
[276]
HepG2.C3A MAP3K8
Mean 11.3
Standard deviation 2.4
Values 13 9.6
[277]
HuH.7 MAP3K8
Mean 6.17
Standard deviation 0.35
Values 6.6 6.1 5.9
[278]
SNU475 MAP3K8
Mean 3.37
Standard deviation 0.26
Values 3.6 3.2
[279]
THLE MAP3K8
Mean 9.43
Standard deviation 0.46
Values 9.8 9.1
[280]
liver MAP3K8
Mean 3.4
Standard deviation 1
Values 4.8 3.3 3.1 2.4
[281]
ref_hepatocyte MAP2K6
Mean 1.65
Standard deviation 2.1
Values 0.17 1.1 0.98 5.3 0.69
[282]
HepG2 MAP2K6
Mean 4.46
Standard deviation 1.8
Values 5.7 3.2
[283]
HepG2.C3A MAP2K6
Mean 0.428
Standard deviation 0.00091
Values 0.43 0.43
[284]
HuH.7 MAP2K6
Mean 11.9
Standard deviation 2.1
Values 13 9.5 13
[285]
SNU475 MAP2K6
Mean 6.1
Standard deviation 1.1
Values 5.4 6.8
[286]
THLE MAP2K6
Mean 0.418
Standard deviation 0.064
Values 0.37 0.46
[287]
liver MAP2K6
Mean 0.764
Standard deviation 0.64
Values 0.79 0.61 1.6 0.051
[288]
ref_hepatocyte MAP3K3
Mean 1.6
Standard deviation 0.37
Values 1.8 1.5 2 1.7 1
[289]
HepG2 MAP3K3
Mean 10.9
Standard deviation 0.66
Values 11 10
[290]
HepG2.C3A MAP3K3
Mean 13.6
Standard deviation 1.7
Values 12 15
[291]
HuH.7 MAP3K3
Mean 7.9
Standard deviation 0.73
Values 7.9 7.2 8.6
[292]
SNU475 MAP3K3
Mean 12.4
Standard deviation 2.3
Values 11 14
[293]
THLE MAP3K3
Mean 16.6
Standard deviation 2.1
Values 15 18
[294]
liver MAP3K3
Mean 10
Standard deviation 4.6
Values 15 13 6.9 5.5
[295]
ref_hepatocyte IRAK4
Mean 1.45
Standard deviation 0.56
Values 0.79 1.9 2.1 1.6 0.94
[296]
HepG2 IRAK4
Mean 3.82
Standard deviation 0.94
Values 4.5 3.2
[297]
HepG2.C3A IRAK4
Mean 8.76
Standard deviation 1.5
Values 9.8 7.7
[298]
HuH.7 IRAK4
Mean 10.2
Standard deviation 0.57
Values 9.8 11 9.9
[299]
SNU475 IRAK4
Mean 7.11
Standard deviation 2.2
Values 5.5 8.7
[300]
THLE IRAK4
Mean 6.73
Standard deviation 0.64
Values 6.3 7.2
[301]
liver IRAK4
Mean 7.06
Standard deviation 1.8
Values 7.5 9.3 5.4 6
[302]
ref_hepatocyte MAP3K1
Mean 1.15
Standard deviation 0.91
Values 1.1 0.9 0.47 2.7 0.56
[303]
HepG2 MAP3K1
Mean 16
Standard deviation 5.2
Values 20 12
[304]
HepG2.C3A MAP3K1
Mean 11.7
Standard deviation 2.9
Values 14 9.6
[305]
HuH.7 MAP3K1
Mean 9.28
Standard deviation 2.5
Values 6.5 11 10
[306]
SNU475 MAP3K1
Mean 10.6
Standard deviation 2.4
Values 8.9 12
[307]
THLE MAP3K1
Mean 5.47
Standard deviation 0.12
Values 5.5 5.4
[308]
liver MAP3K1
Mean 11.4
Standard deviation 4.8
Values 14 17 7.7 7
[309]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[310]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[311]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[312]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[313]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[314]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[315]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8
[316]
ref_hepatocyte RPS6KA5
Mean 0.385
Standard deviation 0.19
Values 0.65 0.46 0.18 0.21 0.42
[317]
HepG2 RPS6KA5
Missing
[318]
HepG2.C3A RPS6KA5
Missing
[319]
HuH.7 RPS6KA5
Missing
[320]
SNU475 RPS6KA5
Missing
[321]
THLE RPS6KA5
Missing
[322]
liver RPS6KA5
Missing
[323]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0.22 0.64 0.71 0 0.34
[324]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.88 0.62
[325]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.71 0.53
[326]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.49 0.2 0.28
[327]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 0.66 1.1
[328]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[329]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.75 0.49 0.96 0.23
[330]
ref_hepatocyte IL1A
Mean 0.05
Standard deviation 0.11
Values 0.25 0 0 0 0
[331]
HepG2 IL1A
Mean 0.0823
Standard deviation 0.035
Values 0.11 0.057
[332]
HepG2.C3A IL1A
Mean 0.0555
Standard deviation 0.018
Values 0.043 0.068
[333]
HuH.7 IL1A
Mean 0.0235
Standard deviation 0.041
Values 0 0.071 0
[334]
SNU475 IL1A
Mean 0.0589
Standard deviation 0.024
Values 0.076 0.042
[335]
THLE IL1A
Mean 7.11
Standard deviation 1.8
Values 8.4 5.8
[336]
liver IL1A
Mean 0.0237
Standard deviation 0.034
Values 0 0.071 0.024 0
[337]
ref_hepatocyte MAPK10
Mean 0.00272
Standard deviation 0.0061
Values 0.014 0 0 0 0
[338]
HepG2 MAPK10
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[339]
HepG2.C3A MAPK10
Mean 0
Standard deviation 0
Values 0 0
[340]
HuH.7 MAPK10
Mean 0
Standard deviation 0
Values 0 0 0
[341]
SNU475 MAPK10
Mean 2.4
Standard deviation 0.56
Values 2 2.8
[342]
THLE MAPK10
Mean 0.14
Standard deviation 0.07
Values 0.19 0.09
[343]
liver MAPK10
Mean 0.586
Standard deviation 0.14
Values 0.49 0.8 0.52 0.54
[344]
ref_hepatocyte MIR718
Missing
[345]
HepG2 MIR718
Missing
[346]
HepG2.C3A MIR718
Missing
[347]
HuH.7 MIR718
Missing
[348]
SNU475 MIR718
Missing
[349]
THLE MIR718
Missing
[350]
liver MIR718
Missing