WP_INTERFERON_TYPE_I_SIGNALING_PATHWAYS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RPS6 40S ribosomal protein S6 [1] [2] [3] [4] [5] [6] [7]
2 EIF4A1 Eukaryotic initiation factor 4A-I [8] [9] [10] [11] [12] [13] [14]
3 EIF4B Eukaryotic translation initiation factor 4B [15] 1.89[16] 2.81[17] 2.79[18] 1.08[19] 1.50[20] 0.88[21]
4 RAC1 Ras-related C3 botulinum toxin substrate 1 [22] 0.90[23] 0.27[24] 0.74[25] 1.21[26] 1.25[27] -0.14[28]
5 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 [29] 0.30[30] -0.32[31] 0.05[32] -2.10[33] -0.50[34] -0.77[35]
6 PRMT1 Protein arginine N-methyltransferase 1 [36] 1.54[37] 1.28[38] 1.51[39] 0.12[40] 0.30[41] -1.12[42]
7 MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 [43] 0.08[44] 0.07[45] -1.27[46] -0.63[47] -0.71[48] -0.61[49]
8 STAT3 Signal transducer and activator of transcription 3 [50] 1.85[51] 0.04[52] 0.54[53] 1.44[54] 0.77[55] 3.23[56]
9 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [57] 1.74[58] 1.87[59] 1.59[60] 2.09[61] 2.78[62] 2.08[63]
10 PDCD4 Programmed cell death protein 4 [64] -0.84[65] 0.28[66] 0.61[67] -0.62[68] -0.53[69] -0.30[70]
11 STAT1 Signal transducer and activator of transcription 1-alpha/beta [71] 1.22[72] 0.00[73] 0.87[74] 3.73[75] 1.52[76] 1.78[77]
12 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 [78] 1.28[79] 0.73[80] 0.71[81] 1.28[82] 1.52[83] 0.64[84]
13 CRK Adapter molecule crk [85] 1.09[86] 0.72[87] 0.55[88] 0.96[89] 1.41[90] 1.67[91]
14 RAP1A Ras-related protein Rap-1A [92] 0.25[93] -0.12[94] 0.48[95] 0.98[96] 0.80[97] -0.46[98]
15 JAK1 Tyrosine-protein kinase JAK1 [99] 1.81[100] 0.99[101] 0.93[102] 1.83[103] 2.52[104] 2.36[105]
16 EIF4E Eukaryotic translation initiation factor 4E [106] 1.44[107] 1.96[108] 1.08[109] 0.92[110] 2.01[111] 1.00[112]
17 IRF9 Interferon regulatory factor 9 [113] 0.48[114] -1.65[115] -1.61[116] 0.83[117] -0.15[118] 0.73[119]
18 IFNAR2 Interferon alpha/beta receptor 2 [120] 0.08[121] -0.56[122] -0.12[123] -0.19[124] -0.15[125] 0.05[126]
19 SOCS3 Suppressor of cytokine signaling 3 [127] -2.84[128] -3.56[129] -2.08[130] 0.40[131] -0.62[132] 0.96[133]
20 MLST8 Target of rapamycin complex subunit LST8 [134] 1.12[135] 1.15[136] 1.28[137] 0.22[138] 0.63[139] 0.26[140]
21 MAPK14 Mitogen-activated protein kinase 14 [141] 2.77[142] 2.53[143] 1.87[144] 2.88[145] 2.41[146] 2.11[147]
22 CRKL Crk-like protein [148] 3.00[149] 2.79[150] 3.16[151] 2.32[152] 2.58[153] 2.28[154]
23 IFNAR1 Interferon alpha/beta receptor 1 [155] 1.36[156] 1.52[157] 0.99[158] 2.18[159] 2.23[160] 3.26[161]
24 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [162] 0.82[163] 0.64[164] 1.49[165] 3.27[166] 2.82[167] 3.83[168]
25 STAT2 Signal transducer and activator of transcription 2 [169] 1.32[170] 2.38[171] 1.30[172] 2.73[173] 2.24[174] 3.85[175]
26 PTPN6 Tyrosine-protein phosphatase non-receptor type 6 [176] 0.83[177] 0.72[178] 1.06[179] -5.94[180] -0.87[181] 0.65[182]
27 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [183] 3.17[184] 3.09[185] 3.46[186] 1.91[187] 2.52[188] 0.54[189]
28 RPS6KA4 Ribosomal protein S6 kinase alpha-4 [190] [191] [192] [193] [194] [195] [196]
29 RAPGEF1 Rap guanine nucleotide exchange factor 1 [197] 3.38[198] 2.91[199] 2.39[200] 2.46[201] 2.18[202] 2.00[203]
30 TYK2 Non-receptor tyrosine-protein kinase TYK2 [204] 2.43[205] 2.49[206] 2.38[207] 1.95[208] 2.93[209] 2.82[210]
31 MTOR Serine/threonine-protein kinase mTOR [211] 3.83[212] 4.54[213] 3.87[214] 3.88[215] 4.02[216] 4.28[217]
32 RPS6KB1 Ribosomal protein S6 kinase beta-1 [218] [219] [220] [221] [222] [223] [224]
33 IRS1 Insulin receptor substrate 1 [225] 3.39[226] 2.53[227] 3.72[228] 2.91[229] 2.54[230] 2.94[231]
34 PIAS1 E3 SUMO-protein ligase PIAS1 [232] 1.34[233] 1.29[234] 1.96[235] 2.07[236] 1.85[237] 2.01[238]
35 STAT5A Signal transducer and activator of transcription 5A [239] -0.65[240] 0.22[241] -0.95[242] 0.35[243] 1.17[244] 1.06[245]
36 IRS2 Insulin receptor substrate 2 [246] -4.36[247] [248] -2.04[249] 0.53[250] 4.42[251] 3.21[252]
37 SOCS1 Suppressor of cytokine signaling 1 [253] -0.15[254] 0.41[255] 0.44[256] -0.59[257] -1.92[258] -0.64[259]
38 FYN Tyrosine-protein kinase Fyn [260] 2.24[261] -6.67[262] 1.66[263] 2.67[264] 4.25[265] 1.80[266]
39 RPTOR Regulatory-associated protein of mTOR [267] 4.38[268] 3.31[269] 3.17[270] 3.05[271] 3.34[272] 3.16[273]
40 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.18[274] 3.96[275] -0.09[276] 1.48[277] 2.30[278] 1.12[279]
41 CREB1 Cyclic AMP-responsive element-binding protein 1 [280] 3.02[281] 3.87[282] 4.12[283] 3.74[284] 3.74[285] 3.17[286]
42 MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 [287] 1.59[288] -1.93[289] 2.68[290] 2.21[291] -1.77[292] -0.79[293]
43 GAB2 GRB2-associated-binding protein 2 [294] 2.86[295] 2.34[296] 2.35[297] 2.12[298] 2.26[299] 1.37[300]
44 PIAS3 E3 SUMO-protein ligase PIAS3 [301] 2.60[302] 1.48[303] 2.54[304] 3.91[305] 3.67[306] 1.59[307]
45 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 [308] 3.95[309] 3.36[310] 2.85[311] 3.52[312] 2.46[313] 3.63[314]
46 PTPRC Receptor-type tyrosine-protein phosphatase C [315] [316] [317] [318] 1.57[319] -7.29[320] 3.97[321]
47 STAT4 Signal transducer and activator of transcription 4 [322] -3.54[323] -2.78[324] -2.49[325] 2.83[326] 1.69[327] 1.85[328]
48 CBL E3 ubiquitin-protein ligase CBL [329] 5.74[330] 4.38[331] 4.37[332] 6.33[333] 5.87[334] 4.58[335]
49 REL Proto-oncogene c-Rel [336] 0.78[337] 2.24[338] 1.94[339] 1.35[340] 1.55[341] 3.17[342]
50 VAV1 Proto-oncogene vav [343] -7.20[344] -2.68[345] -4.63[346] -4.89[347] -6.10[348] 2.01[349]
51 RPS6KA5 Ribosomal protein S6 kinase alpha-5 [350] [351] [352] [353] [354] [355] [356]
52 LCK Tyrosine-protein kinase Lck [357] 4.07[358] 3.85[359] -6.38[360] -3.88[361] -4.03[362] 2.06[363]
53 ZAP70 Tyrosine-protein kinase ZAP-70 [364] 2.30[365] 2.21[366] -4.25[367] -4.34[368] -2.95[369] 2.98[370]
54 RACK1 Receptor of activated protein C kinase 1 [371] [372] [373] [374] [375] [376] [377]
55 MIR4680 [378] [379] [380] [381] [382] [383] [384]
[1]
ref_hepatocyte RPS6
Mean 819
Standard deviation 2.5e+02
Values 9e+02 7.2e+02 1.2e+03 6.5e+02 6.1e+02
[2]
HepG2 RPS6
Missing
[3]
HepG2.C3A RPS6
Missing
[4]
HuH.7 RPS6
Missing
[5]
SNU475 RPS6
Missing
[6]
THLE RPS6
Missing
[7]
liver RPS6
Missing
[8]
ref_hepatocyte EIF4A1
Mean 248
Standard deviation 1.5e+02
Values 3.9e+02 95 2e+02 1.4e+02 4.1e+02
[9]
HepG2 EIF4A1
Missing
[10]
HepG2.C3A EIF4A1
Missing
[11]
HuH.7 EIF4A1
Missing
[12]
SNU475 EIF4A1
Missing
[13]
THLE EIF4A1
Missing
[14]
liver EIF4A1
Missing
[15]
ref_hepatocyte EIF4B
Mean 76.3
Standard deviation 32
Values 86 43 49 1.2e+02 82
[16]
HepG2 EIF4B
Mean 255
Standard deviation 11
Values 2.5e+02 2.6e+02
[17]
HepG2.C3A EIF4B
Mean 530
Standard deviation 1.8e+02
Values 4e+02 6.6e+02
[18]
HuH.7 EIF4B
Mean 590
Standard deviation 80
Values 5.3e+02 6.8e+02 5.6e+02
[19]
SNU475 EIF4B
Mean 129
Standard deviation 20
Values 1.1e+02 1.4e+02
[20]
THLE EIF4B
Mean 186
Standard deviation 19
Values 1.7e+02 2e+02
[21]
liver EIF4B
Mean 113
Standard deviation 68
Values 1.5e+02 1.9e+02 62 51
[22]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 81 47 45 28 59
[23]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 86 89
[24]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 57 67
[25]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[26]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 1e+02 89
[27]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[28]
liver RAC1
Mean 37.8
Standard deviation 32
Values 9.5 12 63 67
[29]
ref_hepatocyte EIF4EBP1
Mean 48.7
Standard deviation 38
Values 90 20 87 11 35
[30]
HepG2 EIF4EBP1
Mean 54.1
Standard deviation 26
Values 36 72
[31]
HepG2.C3A EIF4EBP1
Mean 38.6
Standard deviation 15
Values 28 49
[32]
HuH.7 EIF4EBP1
Mean 56.5
Standard deviation 22
Values 73 32 64
[33]
SNU475 EIF4EBP1
Mean 9.08
Standard deviation 1.3
Values 10 8.2
[34]
THLE EIF4EBP1
Mean 29.8
Standard deviation 5
Values 33 26
[35]
liver EIF4EBP1
Mean 22.9
Standard deviation 28
Values 4.4 3.1 62 22
[36]
ref_hepatocyte PRMT1
Mean 40.1
Standard deviation 17
Values 53 15 32 45 56
[37]
HepG2 PRMT1
Mean 105
Standard deviation 22
Values 90 1.2e+02
[38]
HepG2.C3A PRMT1
Mean 96.5
Standard deviation 1.5
Values 95 98
[39]
HuH.7 PRMT1
Mean 128
Standard deviation 40
Values 1.6e+02 83 1.4e+02
[40]
SNU475 PRMT1
Mean 34.9
Standard deviation 0.11
Values 35 35
[41]
THLE PRMT1
Mean 42.7
Standard deviation 5.5
Values 39 47
[42]
liver PRMT1
Mean 14.8
Standard deviation 4.4
Values 11 11 19 18
[43]
ref_hepatocyte MAP2K3
Mean 32.7
Standard deviation 39
Values 1e+02 17 16 11 17
[44]
HepG2 MAP2K3
Mean 31
Standard deviation 5.7
Values 35 27
[45]
HepG2.C3A MAP2K3
Mean 34
Standard deviation 1.9
Values 33 35
[46]
HuH.7 MAP2K3
Mean 15.2
Standard deviation 4.8
Values 18 9.6 18
[47]
SNU475 MAP2K3
Mean 16.9
Standard deviation 1.1
Values 18 16
[48]
THLE MAP2K3
Mean 17.3
Standard deviation 3
Values 15 19
[49]
liver MAP2K3
Mean 17.2
Standard deviation 13
Values 7.1 4.9 30 26
[50]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[51]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[52]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[53]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[54]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[55]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[56]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[57]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 10 7.4 7.5 33 53
[58]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 76 58
[59]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 92 68
[60]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 61 77 86
[61]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 76 75
[62]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[63]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 80 99 60 62
[64]
ref_hepatocyte PDCD4
Mean 21.4
Standard deviation 19
Values 5.7 13 11 54 23
[65]
HepG2 PDCD4
Mean 10.8
Standard deviation 2
Values 12 9.3
[66]
HepG2.C3A PDCD4
Mean 25.8
Standard deviation 4.1
Values 23 29
[67]
HuH.7 PDCD4
Mean 36.6
Standard deviation 5.2
Values 32 42 35
[68]
SNU475 PDCD4
Mean 11.1
Standard deviation 7.2
Values 6.1 16
[69]
THLE PDCD4
Mean 12.8
Standard deviation 0.24
Values 13 13
[70]
liver PDCD4
Mean 13.9
Standard deviation 5.7
Values 7.3 12 16 20
[71]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 19 18 12 17 35
[72]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 49 36
[73]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 25 15
[74]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 40 38 47
[75]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 1.1e+02 3.2e+02
[76]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[77]
liver STAT1
Mean 55.8
Standard deviation 15
Values 38 69 49 67
[78]
ref_hepatocyte MAPKAP1
Mean 18.9
Standard deviation 8.4
Values 18 13 16 14 33
[79]
HepG2 MAPKAP1
Mean 41.3
Standard deviation 6.5
Values 46 37
[80]
HepG2.C3A MAPKAP1
Mean 31
Standard deviation 5.4
Values 35 27
[81]
HuH.7 MAPKAP1
Mean 34.6
Standard deviation 7.1
Values 40 26 38
[82]
SNU475 MAPKAP1
Mean 36.6
Standard deviation 8.3
Values 31 43
[83]
THLE MAPKAP1
Mean 46.7
Standard deviation 15
Values 36 57
[84]
liver MAPKAP1
Mean 23.6
Standard deviation 2.7
Values 25 26 23 20
[85]
ref_hepatocyte CRK
Mean 18.5
Standard deviation 12
Values 19 8.5 11 16 38
[86]
HepG2 CRK
Mean 35.5
Standard deviation 2.8
Values 38 34
[87]
HepG2.C3A CRK
Mean 30.2
Standard deviation 5.3
Values 34 27
[88]
HuH.7 CRK
Mean 30.3
Standard deviation 2.4
Values 28 32 32
[89]
SNU475 CRK
Mean 28.8
Standard deviation 1.2
Values 28 30
[90]
THLE CRK
Mean 42.5
Standard deviation 6.6
Values 38 47
[91]
liver CRK
Mean 47.1
Standard deviation 5.8
Values 47 55 41 45
[92]
ref_hepatocyte RAP1A
Mean 17.1
Standard deviation 7.2
Values 8.5 28 13 17 20
[93]
HepG2 RAP1A
Mean 18.3
Standard deviation 5.4
Values 22 14
[94]
HepG2.C3A RAP1A
Mean 15.6
Standard deviation 1.3
Values 17 15
[95]
HuH.7 RAP1A
Mean 26.7
Standard deviation 1.9
Values 26 29 25
[96]
SNU475 RAP1A
Mean 27.1
Standard deviation 7
Values 22 32
[97]
THLE RAP1A
Mean 25.7
Standard deviation 2.2
Values 24 27
[98]
liver RAP1A
Mean 9.95
Standard deviation 5.1
Values 5.3 7.4 17 10
[99]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 18 10 14 6.8 27
[100]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 56 40
[101]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 29 31
[102]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 29 32 36
[103]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 39 47
[104]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[105]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 62 75 54 58
[106]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 13 10 7.1 17 28
[107]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 42 31
[108]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 72 43
[109]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[110]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 22 23
[111]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[112]
liver EIF4E
Mean 24
Standard deviation 12
Values 12 16 33 36
[113]
ref_hepatocyte IRF9
Mean 13
Standard deviation 3.9
Values 14 16 17 7.9 10
[114]
HepG2 IRF9
Mean 16.3
Standard deviation 3.8
Values 14 19
[115]
HepG2.C3A IRF9
Mean 4.11
Standard deviation 0.77
Values 3.6 4.7
[116]
HuH.7 IRF9
Mean 4.77
Standard deviation 2
Values 4.6 6.9 2.8
[117]
SNU475 IRF9
Mean 18.5
Standard deviation 3.8
Values 16 21
[118]
THLE IRF9
Mean 10.1
Standard deviation 0.59
Values 9.7 11
[119]
liver IRF9
Mean 17.3
Standard deviation 10
Values 7.3 9.7 24 28
[120]
ref_hepatocyte IFNAR2
Mean 12.8
Standard deviation 6.4
Values 22 7.5 9.2 8 18
[121]
HepG2 IFNAR2
Mean 12.2
Standard deviation 0.31
Values 12 12
[122]
HepG2.C3A IFNAR2
Mean 8.58
Standard deviation 1.2
Values 7.7 9.4
[123]
HuH.7 IFNAR2
Mean 13.2
Standard deviation 0.52
Values 13 14 13
[124]
SNU475 IFNAR2
Mean 8.96
Standard deviation 1.9
Values 7.6 10
[125]
THLE IFNAR2
Mean 9.98
Standard deviation 0.57
Values 9.6 10
[126]
liver IFNAR2
Mean 10.6
Standard deviation 1.7
Values 9.4 11 9 13
[127]
ref_hepatocyte SOCS3
Mean 11.2
Standard deviation 10
Values 19 10 24 1 1.5
[128]
HepG2 SOCS3
Mean 1.4
Standard deviation 0.4
Values 1.1 1.7
[129]
HepG2.C3A SOCS3
Mean 0.939
Standard deviation 0.87
Values 0.32 1.6
[130]
HuH.7 SOCS3
Mean 2.97
Standard deviation 2.7
Values 1.4 6.1 1.4
[131]
SNU475 SOCS3
Mean 11.8
Standard deviation 0.67
Values 11 12
[132]
THLE SOCS3
Mean 6.29
Standard deviation 1.1
Values 7.1 5.5
[133]
liver SOCS3
Mean 17.4
Standard deviation 5.5
Values 26 14 15 15
[134]
ref_hepatocyte MLST8
Mean 10
Standard deviation 3.8
Values 14 10 14 7 5.5
[135]
HepG2 MLST8
Mean 19.6
Standard deviation 1.4
Values 19 21
[136]
HepG2.C3A MLST8
Mean 22
Standard deviation 3.6
Values 19 24
[137]
HuH.7 MLST8
Mean 27.2
Standard deviation 3.6
Values 30 23 28
[138]
SNU475 MLST8
Mean 9.36
Standard deviation 0.84
Values 8.8 9.9
[139]
THLE MLST8
Mean 13.3
Standard deviation 1.9
Values 12 15
[140]
liver MLST8
Mean 9.64
Standard deviation 7.6
Values 3.8 2.5 17 15
[141]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[142]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[143]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[144]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[145]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[146]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[147]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[148]
ref_hepatocyte CRKL
Mean 7.86
Standard deviation 3.2
Values 7.1 5.2 6.1 13 7.5
[149]
HepG2 CRKL
Mean 56.6
Standard deviation 7.1
Values 62 52
[150]
HepG2.C3A CRKL
Mean 53.9
Standard deviation 8
Values 48 60
[151]
HuH.7 CRKL
Mean 78.7
Standard deviation 6.8
Values 74 76 86
[152]
SNU475 CRKL
Mean 31.5
Standard deviation 0.52
Values 31 32
[153]
THLE CRKL
Mean 40.6
Standard deviation 0.46
Values 41 40
[154]
liver CRKL
Mean 30.6
Standard deviation 3.9
Values 33 32 25 32
[155]
ref_hepatocyte IFNAR1
Mean 7.46
Standard deviation 3.8
Values 3.9 12 11 3.7 6.8
[156]
HepG2 IFNAR1
Mean 17.2
Standard deviation 4.5
Values 20 14
[157]
HepG2.C3A IFNAR1
Mean 21.2
Standard deviation 0.44
Values 22 21
[158]
HuH.7 IFNAR1
Mean 16.6
Standard deviation 2.6
Values 14 19 17
[159]
SNU475 IFNAR1
Mean 27.1
Standard deviation 2
Values 26 29
[160]
THLE IFNAR1
Mean 30.2
Standard deviation 1.7
Values 29 31
[161]
liver IFNAR1
Mean 57.2
Standard deviation 9.6
Values 49 70 50 60
[162]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.2 14 8.1 4.1 7.4
[163]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 14 9.8
[164]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 13 9.6
[165]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 15 32 23
[166]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 35 80
[167]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[168]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1.4e+02 1e+02 64 32
[169]
ref_hepatocyte STAT2
Mean 5.97
Standard deviation 4.9
Values 2.3 13 9.4 2.5 2.7
[170]
HepG2 STAT2
Mean 13.4
Standard deviation 4
Values 16 11
[171]
HepG2.C3A STAT2
Mean 30.9
Standard deviation 3.5
Values 28 33
[172]
HuH.7 STAT2
Mean 16.5
Standard deviation 0.99
Values 17 16 16
[173]
SNU475 STAT2
Mean 31.7
Standard deviation 16
Values 20 43
[174]
THLE STAT2
Mean 24.3
Standard deviation 2
Values 26 23
[175]
liver STAT2
Mean 69
Standard deviation 4.2
Values 68 74 70 64
[176]
ref_hepatocyte PTPN6
Mean 5.33
Standard deviation 3
Values 4.4 9.3 7.6 2.2 3.1
[177]
HepG2 PTPN6
Mean 8.54
Standard deviation 0.054
Values 8.6 8.5
[178]
HepG2.C3A PTPN6
Mean 8.69
Standard deviation 0.18
Values 8.8 8.6
[179]
HuH.7 PTPN6
Mean 12.4
Standard deviation 1.9
Values 14 10 13
[180]
SNU475 PTPN6
Mean 0.0694
Standard deviation 0.026
Values 0.051 0.088
[181]
THLE PTPN6
Mean 2.52
Standard deviation 0.67
Values 2 3
[182]
liver PTPN6
Mean 6.69
Standard deviation 2
Values 5.4 4.8 7.5 9.1
[183]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 3.1 3.8 4.9 11 3.2
[184]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 41 44
[185]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 35 53
[186]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 64 55 75
[187]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 13 18
[188]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[189]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6.9 6 7.6 3.8
[190]
ref_hepatocyte RPS6KA4
Mean 5.12
Standard deviation 3.9
Values 10 1.8 3.7 1.6 8.4
[191]
HepG2 RPS6KA4
Missing
[192]
HepG2.C3A RPS6KA4
Missing
[193]
HuH.7 RPS6KA4
Missing
[194]
SNU475 RPS6KA4
Missing
[195]
THLE RPS6KA4
Missing
[196]
liver RPS6KA4
Missing
[197]
ref_hepatocyte RAPGEF1
Mean 4.9
Standard deviation 2.3
Values 7.5 2.6 2.5 6.6 5.4
[198]
HepG2 RAPGEF1
Mean 46
Standard deviation 2.9
Values 44 48
[199]
HepG2.C3A RAPGEF1
Mean 36.5
Standard deviation 6.8
Values 32 41
[200]
HuH.7 RAPGEF1
Mean 28.7
Standard deviation 4.9
Values 23 33 30
[201]
SNU475 RAPGEF1
Mean 21.5
Standard deviation 2.8
Values 20 23
[202]
THLE RAPGEF1
Mean 19.2
Standard deviation 5.1
Values 16 23
[203]
liver RAPGEF1
Mean 15.7
Standard deviation 4.8
Values 19 19 16 8.9
[204]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 5.2 5.6 6.8 2.6 4
[205]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 24 23
[206]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 25 29
[207]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 31 19 35
[208]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[209]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[210]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 30 24 31 24
[211]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[212]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[213]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[214]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[215]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[216]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[217]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[218]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 1.9 2.1 2 5.1 4.9
[219]
HepG2 RPS6KB1
Missing
[220]
HepG2.C3A RPS6KB1
Missing
[221]
HuH.7 RPS6KB1
Missing
[222]
SNU475 RPS6KB1
Missing
[223]
THLE RPS6KB1
Missing
[224]
liver RPS6KB1
Missing
[225]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[226]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[227]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[228]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[229]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[230]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[231]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[232]
ref_hepatocyte PIAS1
Mean 2.96
Standard deviation 1.1
Values 4.9 2.7 2.2 2.2 2.9
[233]
HepG2 PIAS1
Mean 6.75
Standard deviation 3.6
Values 9.3 4.2
[234]
HepG2.C3A PIAS1
Mean 7.18
Standard deviation 2
Values 8.6 5.7
[235]
HuH.7 PIAS1
Mean 12.9
Standard deviation 1.7
Values 12 12 15
[236]
SNU475 PIAS1
Mean 9.97
Standard deviation 0.61
Values 9.5 10
[237]
THLE PIAS1
Mean 9.23
Standard deviation 0.13
Values 9.1 9.3
[238]
liver PIAS1
Mean 9.55
Standard deviation 5.5
Values 4.3 5.5 15 13
[239]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 5 0.95 1.5 1.8 2.7
[240]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.3 1.4
[241]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.9 2.6
[242]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.2 1.8 1.1
[243]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.3 2.5
[244]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[245]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 6.2 3.5 3 3.3
[246]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 1.4 2.9 5.7 0.019 0.61
[247]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.043 0.14
[248]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[249]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.17 1.4 0.2
[250]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.8 2.1
[251]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[252]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 17 11 29 6.3
[253]
ref_hepatocyte SOCS1
Mean 2.1
Standard deviation 1.9
Values 1.3 3.4 4.7 1.1 0
[254]
HepG2 SOCS1
Mean 1.7
Standard deviation 0.19
Values 1.6 1.8
[255]
HepG2.C3A SOCS1
Mean 2.76
Standard deviation 1.3
Values 1.9 3.7
[256]
HuH.7 SOCS1
Mean 3.19
Standard deviation 2.1
Values 5.3 1 3.3
[257]
SNU475 SOCS1
Mean 1.11
Standard deviation 0.23
Values 0.95 1.3
[258]
THLE SOCS1
Mean 0.479
Standard deviation 0.076
Values 0.53 0.43
[259]
liver SOCS1
Mean 1.08
Standard deviation 0.8
Values 2.2 0.27 1.1 0.8
[260]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 0.23 5.5 2.6 2.2 0.039
[261]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 8.4 9.4
[262]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[263]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.5 4.8 8.9
[264]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 8.9 12
[265]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[266]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 5 4.4 8.9 5.1
[267]
ref_hepatocyte RPTOR
Mean 1.96
Standard deviation 0.72
Values 2.6 1.2 1.1 2.5 2.4
[268]
HepG2 RPTOR
Mean 36.8
Standard deviation 1
Values 38 36
[269]
HepG2.C3A RPTOR
Mean 19.3
Standard deviation 0.98
Values 19 20
[270]
HuH.7 RPTOR
Mean 19.8
Standard deviation 7.4
Values 17 14 28
[271]
SNU475 RPTOR
Mean 13
Standard deviation 0.49
Values 13 13
[272]
THLE RPTOR
Mean 17.1
Standard deviation 3.1
Values 15 19
[273]
liver RPTOR
Mean 14.1
Standard deviation 7.6
Values 21 20 7.5 7.6
[274]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 3.3 0.66 0.38 4.1 0.94
[275]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 13 18
[276]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 27 31
[277]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 1.6 2.3 2
[278]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 3.7 4.6
[279]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[280]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 5.1 3 2.4 2.6
[281]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 1.5 0.81 0.96 3.7 2.1
[282]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 15 11
[283]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 28 24
[284]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 31 36 38
[285]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[286]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[287]
liver CREB1
Mean 13
Standard deviation 3.1
Values 15 16 12 9.3
[288]
ref_hepatocyte MAP2K6
Mean 1.65
Standard deviation 2.1
Values 0.17 1.1 0.98 5.3 0.69
[289]
HepG2 MAP2K6
Mean 4.46
Standard deviation 1.8
Values 5.7 3.2
[290]
HepG2.C3A MAP2K6
Mean 0.428
Standard deviation 0.00091
Values 0.43 0.43
[291]
HuH.7 MAP2K6
Mean 11.9
Standard deviation 2.1
Values 13 9.5 13
[292]
SNU475 MAP2K6
Mean 6.1
Standard deviation 1.1
Values 5.4 6.8
[293]
THLE MAP2K6
Mean 0.418
Standard deviation 0.064
Values 0.37 0.46
[294]
liver MAP2K6
Mean 0.764
Standard deviation 0.64
Values 0.79 0.61 1.6 0.051
[295]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 4.5 0.31 0.25 1.2 1.9
[296]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 7.1 14
[297]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 5.9 10
[298]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 6.6 12 9.6
[299]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 5.1 6.1
[300]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[301]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 4.6 4.2 2.8 1.8
[302]
ref_hepatocyte PIAS3
Mean 1.39
Standard deviation 0.72
Values 2 1.3 2.1 0.36 1.1
[303]
HepG2 PIAS3
Mean 7.59
Standard deviation 0.22
Values 7.4 7.7
[304]
HepG2.C3A PIAS3
Mean 3.85
Standard deviation 0.47
Values 4.2 3.5
[305]
HuH.7 PIAS3
Mean 9.07
Standard deviation 2.5
Values 10 6.2 11
[306]
SNU475 PIAS3
Mean 16.8
Standard deviation 3.3
Values 14 19
[307]
THLE PIAS3
Mean 15.3
Standard deviation 1.8
Values 14 17
[308]
liver PIAS3
Mean 3.37
Standard deviation 2.5
Values 1.4 1.2 4.5 6.4
[309]
ref_hepatocyte MAP3K1
Mean 1.15
Standard deviation 0.91
Values 1.1 0.9 0.47 2.7 0.56
[310]
HepG2 MAP3K1
Mean 16
Standard deviation 5.2
Values 20 12
[311]
HepG2.C3A MAP3K1
Mean 11.7
Standard deviation 2.9
Values 14 9.6
[312]
HuH.7 MAP3K1
Mean 9.28
Standard deviation 2.5
Values 6.5 11 10
[313]
SNU475 MAP3K1
Mean 10.6
Standard deviation 2.4
Values 8.9 12
[314]
THLE MAP3K1
Mean 5.47
Standard deviation 0.12
Values 5.5 5.4
[315]
liver MAP3K1
Mean 11.4
Standard deviation 4.8
Values 14 17 7.7 7
[316]
ref_hepatocyte PTPRC
Mean 1.02
Standard deviation 1.6
Values 0.46 3.8 0.76 0 0.047
[317]
HepG2 PTPRC
Mean 0
Standard deviation 0
Values 0 0
[318]
HepG2.C3A PTPRC
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 PTPRC
Mean 0
Standard deviation 0
Values 0 0 0
[320]
SNU475 PTPRC
Mean 2.42
Standard deviation 0.6
Values 2 2.9
[321]
THLE PTPRC
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[322]
liver PTPRC
Mean 12.8
Standard deviation 4
Values 16 17 8.5 10
[323]
ref_hepatocyte STAT4
Mean 0.825
Standard deviation 0.62
Values 0.35 1.3 1 0 1.4
[324]
HepG2 STAT4
Mean 0.0637
Standard deviation 0.025
Values 0.082 0.046
[325]
HepG2.C3A STAT4
Mean 0.119
Standard deviation 0.044
Values 0.15 0.087
[326]
HuH.7 STAT4
Mean 0.164
Standard deviation 0.023
Values 0.19 0.14 0.16
[327]
SNU475 STAT4
Mean 4.7
Standard deviation 1.3
Values 3.8 5.6
[328]
THLE STAT4
Mean 2.3
Standard deviation 1.2
Values 3.1 1.5
[329]
liver STAT4
Mean 2.39
Standard deviation 1.1
Values 3.7 1.5 3 1.4
[330]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.65 0.33 0.18 0.83 0.62
[331]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 25 26
[332]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 10 11
[333]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 9.5 11 15
[334]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 37 30
[335]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[336]
liver CBL
Mean 10
Standard deviation 4.2
Values 14 14 5.8 7.1
[337]
ref_hepatocyte REL
Mean 0.479
Standard deviation 0.49
Values 0.1 0.24 0.23 1.3 0.51
[338]
HepG2 REL
Mean 0.741
Standard deviation 0.46
Values 1.1 0.42
[339]
HepG2.C3A REL
Mean 2.24
Standard deviation 0.8
Values 2.8 1.7
[340]
HuH.7 REL
Mean 2.05
Standard deviation 1.2
Values 0.74 3 2.4
[341]
SNU475 REL
Mean 0.975
Standard deviation 0.12
Values 1.1 0.89
[342]
THLE REL
Mean 1.22
Standard deviation 0.23
Values 1.1 1.4
[343]
liver REL
Mean 3.46
Standard deviation 0.82
Values 4.2 4.1 2.8 2.7
[344]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0.63 1 0.48 0 0.2
[345]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[346]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.097 0.049
[347]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.028 0.019 0.016
[348]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0.025 0
[349]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[350]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 2.6 1.8 0.75 0.82
[351]
ref_hepatocyte RPS6KA5
Mean 0.385
Standard deviation 0.19
Values 0.65 0.46 0.18 0.21 0.42
[352]
HepG2 RPS6KA5
Missing
[353]
HepG2.C3A RPS6KA5
Missing
[354]
HuH.7 RPS6KA5
Missing
[355]
SNU475 RPS6KA5
Missing
[356]
THLE RPS6KA5
Missing
[357]
liver RPS6KA5
Missing
[358]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.49 0.99 0 0.11 0
[359]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 1.7 8
[360]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.7 4.4
[361]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[362]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.025 0.0093
[363]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[364]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 0.91 0.49 1.2 1.7
[365]
ref_hepatocyte ZAP70
Mean 0.182
Standard deviation 0.23
Values 0 0.57 0.2 0.14 0
[366]
HepG2 ZAP70
Mean 0.806
Standard deviation 0.62
Values 0.37 1.2
[367]
HepG2.C3A ZAP70
Mean 0.835
Standard deviation 0.029
Values 0.82 0.86
[368]
HuH.7 ZAP70
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[369]
SNU475 ZAP70
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[370]
THLE ZAP70
Mean 0.0204
Standard deviation 0.021
Values 0.035 0.0053
[371]
liver ZAP70
Mean 1.16
Standard deviation 0.36
Values 1.3 0.87 0.85 1.6
[372]
ref_hepatocyte RACK1
Missing
[373]
HepG2 RACK1
Missing
[374]
HepG2.C3A RACK1
Missing
[375]
HuH.7 RACK1
Missing
[376]
SNU475 RACK1
Missing
[377]
THLE RACK1
Missing
[378]
liver RACK1
Missing
[379]
ref_hepatocyte MIR4680
Missing
[380]
HepG2 MIR4680
Missing
[381]
HepG2.C3A MIR4680
Missing
[382]
HuH.7 MIR4680
Missing
[383]
SNU475 MIR4680
Missing
[384]
THLE MIR4680
Missing
[385]
liver MIR4680
Missing