WP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ANXA5 Annexin A5 [1] -2.98[2] -3.32[3] -3.23[4] -3.13[5] -2.19[6] -3.28[7]
2 FN1 Fibronectin [8] 1.39[9] 1.34[10] 1.40[11] 0.92[12] 1.45[13] 1.50[14]
3 CDC37 Hsp90 co-chaperone Cdc37 [15] -2.86[16] -3.03[17] -2.50[18] -3.81[19] -2.90[20] -2.77[21]
4 NQO1 NAD(P)H dehydrogenase [quinone] 1 [22] 0.65[23] 0.81[24] 0.59[25] 2.09[26] -1.41[27] -6.03[28]
5 ECSIT Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial -3.62[29] -2.43[30] -1.78[31] -4.93[32] -4.29[33] -1.88[34]
6 NFE2L2 Nuclear factor erythroid 2-related factor 2 [35] -1.34[36] 0.07[37] -0.16[38] -1.54[39] -0.97[40] -0.62[41]
7 BMP2 Bone morphogenetic protein 2 [42] -7.08[43] -9.73[44] -0.48[45] -3.89[46] -3.31[47] -2.98[48]
8 EXOC6 Exocyst complex component 6 [49] -2.86[50] -0.28[51] 0.34[52] -2.48[53] -2.45[54] -0.06[55]
9 IGFBP7 Insulin-like growth factor-binding protein 7 [56] -1.79[57] -4.39[58] -4.25[59] 1.07[60] 2.57[61] 3.19[62]
10 DDR1 Epithelial discoidin domain-containing receptor 1 [63] 1.48[64] 1.50[65] -1.54[66] 2.34[67] -0.56[68] -1.93[69]
11 PKD1 Polycystin-1 [70] 1.27[71] 1.66[72] 0.71[73] 0.31[74] 1.50[75] 2.38[76]
12 TGFB1 Transforming growth factor beta-1 [77] 1.37[78] 0.81[79] -1.78[80] 1.84[81] 1.40[82] -2.02[83]
13 SUV39H1 Histone-lysine N-methyltransferase SUV39H1 [84] -1.80[85] -1.43[86] 0.27[87] -1.24[88] -0.93[89] -0.67[90]
14 SIRT1 NAD-dependent protein deacetylase sirtuin-1 [91] -1.60[92] -0.02[93] -0.31[94] -0.44[95] 0.14[96] 0.55[97]
15 NRF1 Nuclear respiratory factor 1 [98] -1.09[99] -0.39[100] -0.24[101] -1.00[102] -0.70[103] -0.31[104]
16 LOXL4 Lysyl oxidase homolog 4 [105] 2.82[106] 1.37[107] -3.94[108] -1.91[109] -2.99[110] -1.39[111]
17 FGF7 Fibroblast growth factor 7 [112] -11.40[113] -7.22[114] [115] -7.37[116] -2.77[117] -2.24[118]
18 COL2A1 Collagen alpha-1(II) chain [119] -1.52[120] 1.74[121] 4.37[122] -4.35[123] -4.29[124] [125]
19 MIR4640 [126] [127] [128] [129] [130] [131] [132]
20 MIR6511B1 [133] [134] [135] [136] [137] [138] [139]
21 MIR1181 [140] [141] [142] [143] [144] [145] [146]
[1]
ref_hepatocyte ANXA5
Mean 206
Standard deviation 1.8e+02
Values 4.7e+02 37 75 1.4e+02 3e+02
[2]
HepG2 ANXA5
Mean 248
Standard deviation 21
Values 2.6e+02 2.3e+02
[3]
HepG2.C3A ANXA5
Mean 125
Standard deviation 15
Values 1.4e+02 1.1e+02
[4]
HuH.7 ANXA5
Mean 114
Standard deviation 7.2
Values 1.2e+02 1.1e+02 1.1e+02
[5]
SNU475 ANXA5
Mean 173
Standard deviation 26
Values 1.5e+02 1.9e+02
[6]
THLE ANXA5
Mean 295
Standard deviation 42
Values 2.7e+02 3.2e+02
[7]
liver ANXA5
Mean 52.1
Standard deviation 40
Values 19 23 1e+02 62
[8]
ref_hepatocyte FN1
Mean 152
Standard deviation 1.4e+02
Values 27 3.8e+02 1.7e+02 1.3e+02 57
[9]
HepG2 FN1
Mean 3.78e+03
Standard deviation 3.9e+02
Values 3.5e+03 4.1e+03
[10]
HepG2.C3A FN1
Mean 2.34e+03
Standard deviation 1.3e+03
Values 1.4e+03 3.2e+03
[11]
HuH.7 FN1
Mean 2.08e+03
Standard deviation 9.6e+02
Values 1.3e+03 3.1e+03 1.8e+03
[12]
SNU475 FN1
Mean 2.11e+03
Standard deviation 1.4e+02
Values 2.2e+03 2e+03
[13]
THLE FN1
Mean 2.73e+03
Standard deviation 1.5e+03
Values 1.7e+03 3.8e+03
[14]
liver FN1
Mean 1.06e+03
Standard deviation 3.8e+02
Values 1.4e+03 1.3e+03 5.9e+02 9.3e+02
[15]
ref_hepatocyte CDC37
Mean 77.7
Standard deviation 56
Values 1.5e+02 29 40 42 1.3e+02
[16]
HepG2 CDC37
Mean 102
Standard deviation 8.8
Values 95 1.1e+02
[17]
HepG2.C3A CDC37
Mean 57.6
Standard deviation 0.71
Values 58 57
[18]
HuH.7 CDC37
Mean 71.5
Standard deviation 19
Values 88 51 75
[19]
SNU475 CDC37
Mean 40.8
Standard deviation 3.1
Values 43 39
[20]
THLE CDC37
Mean 68.3
Standard deviation 6.1
Values 64 73
[21]
liver CDC37
Mean 28
Standard deviation 16
Values 13 14 40 45
[22]
ref_hepatocyte NQO1
Mean 42.1
Standard deviation 85
Values 1.6 0.37 1.4 1.9e+02 13
[23]
HepG2 NQO1
Mean 625
Standard deviation 2.7e+02
Values 4.3e+02 8.1e+02
[24]
HepG2.C3A NQO1
Mean 447
Standard deviation 1.2e+02
Values 5.3e+02 3.6e+02
[25]
HuH.7 NQO1
Mean 329
Standard deviation 90
Values 4e+02 2.3e+02 3.5e+02
[26]
SNU475 NQO1
Mean 1.32e+03
Standard deviation 2.1e+02
Values 1.2e+03 1.5e+03
[27]
THLE NQO1
Mean 103
Standard deviation 3.8
Values 1.1e+02 1e+02
[28]
liver NQO1
Mean 1.58
Standard deviation 1.1
Values 0.97 1.8 0.49 3.1
[29]
ref_hepatocyte ECSIT
Mean 19.7
Standard deviation 9.3
Values 19 27 31 10 11
[30]
HepG2 ECSIT
Mean 15.2
Standard deviation 0.26
Values 15 15
[31]
HepG2.C3A ECSIT
Mean 22.1
Standard deviation 6.4
Values 18 27
[32]
HuH.7 ECSIT
Mean 29.9
Standard deviation 5.2
Values 31 24 34
[33]
SNU475 ECSIT
Mean 4.75
Standard deviation 0.69
Values 5.2 4.3
[34]
THLE ECSIT
Mean 6.56
Standard deviation 0.68
Values 6.1 7
[35]
liver ECSIT
Mean 13.2
Standard deviation 4.8
Values 10 8 17 17
[36]
ref_hepatocyte NFE2L2
Mean 15.6
Standard deviation 4.9
Values 11 19 21 18 9.4
[37]
HepG2 NFE2L2
Mean 58.6
Standard deviation 25
Values 76 41
[38]
HepG2.C3A NFE2L2
Mean 99.8
Standard deviation 19
Values 1.1e+02 86
[39]
HuH.7 NFE2L2
Mean 72.7
Standard deviation 3
Values 74 75 69
[40]
SNU475 NFE2L2
Mean 39.6
Standard deviation 2.1
Values 41 38
[41]
THLE NFE2L2
Mean 52.3
Standard deviation 3.2
Values 55 50
[42]
liver NFE2L2
Mean 25
Standard deviation 9.2
Values 15 21 28 36
[43]
ref_hepatocyte BMP2
Mean 5.74
Standard deviation 7.8
Values 11 0.28 0.49 0 17
[44]
HepG2 BMP2
Mean 0.401
Standard deviation 0.033
Values 0.42 0.38
[45]
HepG2.C3A BMP2
Mean 0.0409
Standard deviation 0.0028
Values 0.043 0.039
[46]
HuH.7 BMP2
Mean 21.5
Standard deviation 8.1
Values 17 31 17
[47]
SNU475 BMP2
Mean 2.85
Standard deviation 0.2
Values 2.7 3
[48]
THLE BMP2
Mean 3.79
Standard deviation 1.9
Values 2.4 5.2
[49]
liver BMP2
Mean 1.79
Standard deviation 0.56
Values 2.4 2.1 1.4 1.3
[50]
ref_hepatocyte EXOC6
Mean 4.15
Standard deviation 2.4
Values 2 3.1 2.6 7.8 5.3
[51]
HepG2 EXOC6
Mean 5.44
Standard deviation 2.5
Values 7.2 3.7
[52]
HepG2.C3A EXOC6
Mean 20.7
Standard deviation 0.32
Values 21 21
[53]
HuH.7 EXOC6
Mean 27.2
Standard deviation 2
Values 26 30 26
[54]
SNU475 EXOC6
Mean 5.46
Standard deviation 0.73
Values 4.9 6
[55]
THLE EXOC6
Mean 4.98
Standard deviation 0.49
Values 4.6 5.3
[56]
liver EXOC6
Mean 9.78
Standard deviation 2.1
Values 6.8 12 10 11
[57]
ref_hepatocyte IGFBP7
Mean 3.92
Standard deviation 4.9
Values 1.4 11 7.4 0.11 0
[58]
HepG2 IGFBP7
Mean 10.8
Standard deviation 2.7
Values 13 8.9
[59]
HepG2.C3A IGFBP7
Mean 1.13
Standard deviation 0.2
Values 1.3 0.99
[60]
HuH.7 IGFBP7
Mean 1.07
Standard deviation 0.42
Values 1.2 1.4 0.59
[61]
SNU475 IGFBP7
Mean 60.4
Standard deviation 15
Values 50 71
[62]
THLE IGFBP7
Mean 152
Standard deviation 26
Values 1.3e+02 1.7e+02
[63]
liver IGFBP7
Mean 88.1
Standard deviation 49
Values 46 46 1.3e+02 1.3e+02
[64]
ref_hepatocyte DDR1
Mean 3.15
Standard deviation 3.1
Values 1.5 0.8 1.6 8.4 3.4
[65]
HepG2 DDR1
Mean 83.6
Standard deviation 33
Values 61 1.1e+02
[66]
HepG2.C3A DDR1
Mean 54
Standard deviation 18
Values 41 67
[67]
HuH.7 DDR1
Mean 5.64
Standard deviation 1.7
Values 4.4 7.5 5
[68]
SNU475 DDR1
Mean 118
Standard deviation 74
Values 65 1.7e+02
[69]
THLE DDR1
Mean 13.9
Standard deviation 3.1
Values 12 16
[70]
liver DDR1
Mean 2.03
Standard deviation 0.43
Values 2 1.5 2.1 2.5
[71]
ref_hepatocyte PKD1
Mean 2.76
Standard deviation 1.7
Values 5.7 1.9 2.3 2.4 1.6
[72]
HepG2 PKD1
Mean 63.2
Standard deviation 14
Values 53 73
[73]
HepG2.C3A PKD1
Mean 52.9
Standard deviation 25
Values 35 71
[74]
HuH.7 PKD1
Mean 23.5
Standard deviation 2.2
Values 21 23 26
[75]
SNU475 PKD1
Mean 25.1
Standard deviation 6.4
Values 21 30
[76]
THLE PKD1
Mean 51
Standard deviation 1.5
Values 52 50
[77]
liver PKD1
Mean 35.2
Standard deviation 30
Values 64 58 11 7
[78]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 0.92 2.3 1.3 5.3 1.3
[79]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 32 77
[80]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 18 29
[81]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 3.7 1.8 4.5
[82]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 53 64
[83]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[84]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 2.3 1.4 1.1 0.62
[85]
ref_hepatocyte SUV39H1
Mean 2.08
Standard deviation 0.87
Values 0.99 1.7 2.2 2.1 3.4
[86]
HepG2 SUV39H1
Mean 5.67
Standard deviation 1.1
Values 6.4 4.9
[87]
HepG2.C3A SUV39H1
Mean 4.68
Standard deviation 1.8
Values 5.9 3.4
[88]
HuH.7 SUV39H1
Mean 13
Standard deviation 6.1
Values 16 6 17
[89]
SNU475 SUV39H1
Mean 6.47
Standard deviation 0.13
Values 6.6 6.4
[90]
THLE SUV39H1
Mean 7.12
Standard deviation 1.7
Values 5.9 8.3
[91]
liver SUV39H1
Mean 3.2
Standard deviation 0.94
Values 2.8 2.1 4 4
[92]
ref_hepatocyte SIRT1
Mean 1.83
Standard deviation 0.67
Values 1.2 2 1.4 2.9 1.6
[93]
HepG2 SIRT1
Mean 5.71
Standard deviation 1.4
Values 6.7 4.7
[94]
HepG2.C3A SIRT1
Mean 10.9
Standard deviation 1
Values 12 10
[95]
HuH.7 SIRT1
Mean 7.67
Standard deviation 1.5
Values 6.3 9.3 7.5
[96]
SNU475 SIRT1
Mean 9.92
Standard deviation 1.6
Values 11 8.8
[97]
THLE SIRT1
Mean 13.2
Standard deviation 0.39
Values 13 13
[98]
liver SIRT1
Mean 6.57
Standard deviation 1.6
Values 7.7 6.2 7.9 4.4
[99]
ref_hepatocyte NRF1
Mean 1.46
Standard deviation 0.56
Values 1.9 0.95 0.84 2.1 1.5
[100]
HepG2 NRF1
Mean 6.49
Standard deviation 0.43
Values 6.8 6.2
[101]
HepG2.C3A NRF1
Mean 6.74
Standard deviation 0.086
Values 6.8 6.7
[102]
HuH.7 NRF1
Mean 6.4
Standard deviation 0.41
Values 6.7 5.9 6.6
[103]
SNU475 NRF1
Mean 5.36
Standard deviation 0.17
Values 5.5 5.2
[104]
THLE NRF1
Mean 5.86
Standard deviation 0.42
Values 5.6 6.2
[105]
liver NRF1
Mean 2.88
Standard deviation 1.4
Values 4.5 3.6 1.9 1.6
[106]
ref_hepatocyte LOXL4
Mean 1.19
Standard deviation 0.88
Values 1.5 0.11 2.5 0.8 1
[107]
HepG2 LOXL4
Mean 79.7
Standard deviation 34
Values 56 1e+02
[108]
HepG2.C3A LOXL4
Mean 18.6
Standard deviation 6.7
Values 14 23
[109]
HuH.7 LOXL4
Mean 0.403
Standard deviation 0.33
Values 0.19 0.78 0.24
[110]
SNU475 LOXL4
Mean 2.33
Standard deviation 0.63
Values 1.9 2.8
[111]
THLE LOXL4
Mean 0.975
Standard deviation 0.16
Values 1.1 0.86
[112]
liver LOXL4
Mean 1.11
Standard deviation 0.35
Values 1.2 1.5 0.66 1.1
[113]
ref_hepatocyte FGF7
Mean 0.61
Standard deviation 0.64
Values 0.46 1.7 0.6 0 0.3
[114]
HepG2 FGF7
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[115]
HepG2.C3A FGF7
Mean 0.0248
Standard deviation 0.02
Values 0.011 0.039
[116]
HuH.7 FGF7
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 FGF7
Mean 0.027
Standard deviation 0.012
Values 0.035 0.019
[118]
THLE FGF7
Mean 0.584
Standard deviation 0.1
Values 0.66 0.51
[119]
liver FGF7
Mean 0.317
Standard deviation 0.15
Values 0.16 0.31 0.28 0.51
[120]
ref_hepatocyte COL2A1
Mean 0.101
Standard deviation 0.12
Values 0.15 0.033 0.026 0.3 0
[121]
HepG2 COL2A1
Mean 0.333
Standard deviation 0.27
Values 0.52 0.14
[122]
HepG2.C3A COL2A1
Mean 2.04
Standard deviation 0.38
Values 2.3 1.8
[123]
HuH.7 COL2A1
Mean 10.9
Standard deviation 6.8
Values 15 3.1 14
[124]
SNU475 COL2A1
Mean 0.0363
Standard deviation 0.0011
Values 0.035 0.037
[125]
THLE COL2A1
Mean 0.0337
Standard deviation 0.0025
Values 0.035 0.032
[126]
liver COL2A1
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte MIR4640
Missing
[128]
HepG2 MIR4640
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A MIR4640
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 MIR4640
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 MIR4640
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[132]
THLE MIR4640
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[133]
liver MIR4640
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte MIR6511B1
Missing
[135]
HepG2 MIR6511B1
Missing
[136]
HepG2.C3A MIR6511B1
Missing
[137]
HuH.7 MIR6511B1
Missing
[138]
SNU475 MIR6511B1
Missing
[139]
THLE MIR6511B1
Missing
[140]
liver MIR6511B1
Missing
[141]
ref_hepatocyte MIR1181
Missing
[142]
HepG2 MIR1181
Missing
[143]
HepG2.C3A MIR1181
Missing
[144]
HuH.7 MIR1181
Missing
[145]
SNU475 MIR1181
Missing
[146]
THLE MIR1181
Missing
[147]
liver MIR1181
Missing