WP_INTEGRINMEDIATED_CELL_ADHESION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ITGB1 | Integrin beta-1 | [1] | 0.01[2] | -0.02[3] | 0.15[4] | 0.65[5] | 0.86[6] | 0.03[7] |
2 | CDC42 | Cell division control protein 42 homolog | [8] | -1.05[9] | -0.39[10] | -1.35[11] | -1.35[12] | -1.94[13] | -2.22[14] |
3 | RAP1B | Ras-related protein Rap-1b | [15] | -2.52[16] | -1.97[17] | -2.15[18] | -1.34[19] | -1.45[20] | -2.02[21] |
4 | CAPNS1 | Calpain small subunit 1 | [22] | -0.77[23] | -1.09[24] | -1.19[25] | -1.60[26] | -1.45[27] | -2.58[28] |
5 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [29] | -0.61[30] | -1.00[31] | -0.25[32] | -0.80[33] | -0.68[34] | -1.10[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | -0.14[37] | -0.43[38] | -1.47[39] | -0.86[40] | -0.71[41] | -0.38[42] |
7 | ILK | Integrin-linked protein kinase | [43] | -1.02[44] | -1.14[45] | -1.18[46] | -1.27[47] | -2.02[48] | -1.59[49] |
8 | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 | [50] | -1.44[51] | -1.20[52] | -2.26[53] | -2.64[54] | -2.64[55] | -1.57[56] |
9 | ZYX | Zyxin | [57] | -0.24[58] | -1.77[59] | -2.03[60] | -0.65[61] | -0.96[62] | -1.62[63] |
10 | VASP | Vasodilator-stimulated phosphoprotein | [64] | -0.36[65] | -0.81[66] | -0.42[67] | -1.05[68] | -1.79[69] | -3.06[70] |
11 | CAPN2 | Calpain-2 catalytic subunit | [71] | -1.00[72] | -2.45[73] | -5.04[74] | 0.41[75] | 0.10[76] | -1.30[77] |
12 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [78] | -1.15[79] | -1.54[80] | -0.92[81] | -1.36[82] | -0.72[83] | -1.32[84] |
13 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [85] | -0.17[86] | -0.55[87] | 0.36[88] | -1.66[89] | -1.04[90] | -1.83[91] |
14 | CAPN1 | Calpain-1 catalytic subunit | [92] | 0.31[93] | -0.94[94] | -0.30[95] | -0.44[96] | -0.65[97] | -0.48[98] |
15 | CAV1 | Caveolin-1 | [99] | -7.06[100] | -9.94[101] | -3.63[102] | 0.56[103] | -0.66[104] | -2.13[105] |
16 | MAPK6 | Mitogen-activated protein kinase 6 | [106] | -0.18[107] | 1.22[108] | 1.40[109] | -0.18[110] | -0.84[111] | -0.20[112] |
17 | GRB2 | Growth factor receptor-bound protein 2 | [113] | 0.98[114] | 0.75[115] | 0.92[116] | -0.26[117] | -0.21[118] | 0.17[119] |
18 | CRK | Adapter molecule crk | [120] | -0.42[121] | -0.55[122] | -0.44[123] | -1.05[124] | -0.52[125] | 0.71[126] |
19 | RAP1A | Ras-related protein Rap-1A | [127] | -1.27[128] | -1.39[129] | -0.51[130] | -1.03[131] | -1.13[132] | -1.42[133] |
20 | SHC1 | SHC-transforming protein 1 | [134] | 0.94[135] | 1.10[136] | 1.22[137] | 1.84[138] | 1.46[139] | 0.65[140] |
21 | ITGAV | Integrin alpha-V | [141] | 1.32[142] | 1.06[143] | 0.45[144] | 1.47[145] | 1.48[146] | 0.30[147] |
22 | ITGA6 | Integrin alpha-6 | [148] | 0.12[149] | 0.46[150] | 0.58[151] | -1.96[152] | -3.46[153] | -0.66[154] |
23 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [155] | -0.28[156] | 0.06[157] | 1.37[158] | -1.00[159] | 0.00[160] | 0.96[161] |
24 | ITGB5 | Integrin beta-5 | [162] | 1.29[163] | 1.34[164] | 0.35[165] | 0.25[166] | 0.54[167] | 0.10[168] |
25 | ARAF | Serine/threonine-protein kinase A-Raf | [169] | -0.68[170] | -1.04[171] | -0.73[172] | -0.91[173] | -0.74[174] | 0.74[175] |
26 | TLN1 | Talin-1 | [176] | 2.77[177] | 1.34[178] | 2.16[179] | 2.29[180] | 2.45[181] | 3.23[182] |
27 | VCL | Vinculin | [183] | 0.55[184] | 0.21[185] | 0.39[186] | 2.02[187] | 1.25[188] | 0.67[189] |
28 | HRAS | GTPase HRas | [190] | -1.23[191] | -1.99[192] | -2.74[193] | -1.76[194] | -1.84[195] | -2.79[196] |
29 | ITGA5 | Integrin alpha-5 | [197] | -1.44[198] | -7.92[199] | -0.69[200] | 1.92[201] | 2.68[202] | 1.00[203] |
30 | CAV2 | Caveolin-2 | [204] | -5.22[205] | -7.36[206] | -1.91[207] | -0.01[208] | -1.17[209] | 0.36[210] |
31 | PAK2 | Serine/threonine-protein kinase PAK 2 | [211] | 1.23[212] | 0.91[213] | 1.25[214] | -0.06[215] | 0.62[216] | 1.23[217] |
32 | MAPK1 | Mitogen-activated protein kinase 1 | [218] | 1.49[219] | 1.57[220] | 1.44[221] | 1.04[222] | 0.82[223] | 1.64[224] |
33 | BCAR1 | Breast cancer anti-estrogen resistance protein 1 | [225] | 0.91[226] | 0.73[227] | -0.36[228] | 0.56[229] | 0.42[230] | -0.07[231] |
34 | AKT2 | RAC-beta serine/threonine-protein kinase | [232] | 0.74[233] | 0.95[234] | 1.12[235] | 0.04[236] | -0.03[237] | 1.00[238] |
35 | CSK | Tyrosine-protein kinase CSK | [239] | 0.16[240] | -0.41[241] | 0.01[242] | -0.83[243] | -1.10[244] | -1.00[245] |
36 | PXN | Paxillin | [246] | 0.78[247] | 0.44[248] | 0.52[249] | 1.30[250] | 1.40[251] | -0.49[252] |
37 | PTK2 | Focal adhesion kinase 1 | [253] | 0.52[254] | 0.94[255] | 1.36[256] | 1.13[257] | 0.47[258] | 0.63[259] |
38 | VAV2 | Guanine nucleotide exchange factor VAV2 | [260] | 1.08[261] | 1.27[262] | 0.80[263] | -1.35[264] | -0.79[265] | 0.38[266] |
39 | SOS1 | Son of sevenless homolog 1 | [267] | -0.32[268] | 1.15[269] | 0.70[270] | 0.03[271] | -0.60[272] | 0.41[273] |
40 | ROCK1 | Rho-associated protein kinase 1 | [274] | -1.17[275] | 0.29[276] | 1.11[277] | 0.55[278] | 0.03[279] | 1.45[280] |
41 | CAPN5 | Calpain-5 | [281] | -2.38[282] | -3.22[283] | -0.18[284] | -1.50[285] | 0.07[286] | 0.97[287] |
42 | ITGA1 | Integrin alpha-1 | [288] | -1.06[289] | -0.01[290] | 0.02[291] | -1.84[292] | -0.35[293] | 3.50[294] |
43 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [295] | 1.65[296] | 1.82[297] | 2.47[298] | -0.11[299] | 0.59[300] | -0.42[301] |
44 | ROCK2 | Rho-associated protein kinase 2 | [302] | 1.26[303] | 2.43[304] | 0.95[305] | 1.82[306] | -0.28[307] | 1.79[308] |
45 | CAPN7 | Calpain-7 | [309] | -0.14[310] | 0.94[311] | 1.96[312] | -0.27[313] | 0.20[314] | 1.21[315] |
46 | SORBS1 | Sorbin and SH3 domain-containing protein 1 | [316] | -1.23[317] | 1.58[318] | 2.33[319] | -4.56[320] | -4.00[321] | 2.82[322] |
47 | GIT2 | ARF GTPase-activating protein GIT2 | [323] | 0.10[324] | 0.56[325] | 0.17[326] | 0.35[327] | 0.28[328] | 0.93[329] |
48 | RAPGEF1 | Rap guanine nucleotide exchange factor 1 | [330] | 1.87[331] | 1.64[332] | 1.40[333] | 0.44[334] | 0.25[335] | 1.04[336] |
49 | PAK4 | Serine/threonine-protein kinase PAK 4 | [337] | 0.67[338] | 0.65[339] | 1.39[340] | 0.21[341] | 0.07[342] | -0.46[343] |
50 | MAP2K5 | Dual specificity mitogen-activated protein kinase kinase 5 | [344] | -0.66[345] | -0.49[346] | 0.56[347] | -1.58[348] | -1.04[349] | -0.58[350] |
51 | RAC2 | Ras-related C3 botulinum toxin substrate 2 | [351] | -1.93[352] | -7.98[353] | -8.55[354] | -2.20[355] | 1.73[356] | -1.36[357] |
52 | SRC | Proto-oncogene tyrosine-protein kinase Src | [358] | 2.80[359] | 2.73[360] | 1.77[361] | 1.58[362] | 0.89[363] | -0.98[364] |
53 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [365] | 2.11[366] | 3.24[367] | 1.99[368] | 0.62[369] | 1.15[370] | 2.37[371] |
54 | ITGB2 | Integrin beta-2 | [372] | 1.07[373] | 2.40[374] | -5.84[375] | -6.00[376] | -7.86[377] | 1.18[378] |
55 | TNS1 | Tensin-1 | [379] | 2.32[380] | 1.79[381] | 0.71[382] | -0.08[383] | 1.48[384] | 3.74[385] |
56 | RAC3 | Ras-related C3 botulinum toxin substrate 3 | [386] | -0.59[387] | 2.41[388] | 1.29[389] | -0.71[390] | -2.05[391] | -3.61[392] |
57 | ITGA3 | Integrin alpha-3 | [393] | 1.73[394] | -3.03[395] | -3.97[396] | 3.57[397] | 3.39[398] | -1.62[399] |
58 | CAPN10 | Calpain-10 | [400] | 0.43[401] | 1.20[402] | 0.46[403] | -0.63[404] | -0.55[405] | -0.34[406] |
59 | ARHGEF7 | Rho guanine nucleotide exchange factor 7 | [407] | 1.40[408] | 1.33[409] | 1.23[410] | 1.00[411] | 0.88[412] | 2.22[413] |
60 | DOCK1 | Dedicator of cytokinesis protein 1 | [414] | 1.76[415] | 2.24[416] | 2.27[417] | -3.46[418] | 1.47[419] | 2.39[420] |
61 | CAPN3 | Calpain-3 | [421] | -3.70[422] | -1.92[423] | -3.22[424] | -6.23[425] | -4.15[426] | 0.32[427] |
62 | PAK1 | Serine/threonine-protein kinase PAK 1 | [428] | -0.23[429] | -1.05[430] | 1.40[431] | -2.67[432] | 1.24[433] | 0.14[434] |
63 | FYN | Tyrosine-protein kinase Fyn | [435] | 0.72[436] | -7.94[437] | 0.67[438] | 0.66[439] | 2.32[440] | 0.84[441] |
64 | ITGA7 | Integrin alpha-7 | [442] | -2.88[443] | -2.57[444] | -1.82[445] | -0.78[446] | 0.91[447] | 0.43[448] |
65 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [449] | 0.07[450] | -3.20[451] | 1.69[452] | 0.20[453] | -3.71[454] | -1.75[455] |
66 | ITGA2 | Integrin alpha-2 | [456] | 3.88[457] | 3.77[458] | 0.85[459] | 0.56[460] | 3.68[461] | -1.11[462] |
67 | ITGB7 | Integrin beta-7 | [463] | -3.31[464] | -0.35[465] | -5.69[466] | -4.28[467] | -4.61[468] | -0.31[469] |
68 | MAPK7 | Mitogen-activated protein kinase 7 | [470] | 1.22[471] | 0.46[472] | 0.49[473] | 0.99[474] | 1.22[475] | 0.20[476] |
69 | ITGB3 | Integrin beta-3 | [477] | -1.85[478] | -4.62[479] | -1.06[480] | 2.04[481] | 1.84[482] | 1.20[483] |
70 | BRAF | Serine/threonine-protein kinase B-raf | [484] | 0.03[485] | -0.30[486] | 1.77[487] | -0.07[488] | -0.25[489] | 1.72[490] |
71 | ITGAL | Integrin alpha-L | [491] | -0.84[492] | 0.95[493] | 2.67[494] | -5.11[495] | -4.88[496] | 2.01[497] |
72 | MAPK12 | Mitogen-activated protein kinase 12 | [498] | 2.60[499] | 2.20[500] | 3.35[501] | 0.67[502] | 2.05[503] | -1.04[504] |
73 | ITGAE | Integrin alpha-E | [505] | 1.72[506] | 2.28[507] | 1.37[508] | 1.33[509] | 1.72[510] | 1.08[511] |
74 | VAV3 | Guanine nucleotide exchange factor VAV3 | [512] | 1.59[513] | -0.18[514] | 2.03[515] | 2.87[516] | -2.97[517] | 1.22[518] |
75 | ITGAM | Integrin alpha-M | [519] | -2.62[520] | -5.23[521] | -3.97[522] | -3.41[523] | -5.69[524] | 2.78[525] |
76 | AKT3 | RAC-gamma serine/threonine-protein kinase | [526] | -2.06[527] | -4.68[528] | -3.95[529] | 5.03[530] | 4.12[531] | 3.48[532] |
77 | ITGAX | Integrin alpha-X | [533] | -0.69[534] | -0.11[535] | -2.09[536] | -2.06[537] | -1.55[538] | 2.17[539] |
78 | MYPN | Myopalladin | [540] | -8.60[541] | -4.88[542] | -6.68[543] | -0.56[544] | -2.01[545] | -3.81[546] |
79 | MAPK4 | Mitogen-activated protein kinase 4 | [547] | -7.14[548] | -5.17[549] | 2.06[550] | -7.22[551] | -4.24[552] | 2.87[553] |
80 | ITGA4 | Integrin alpha-4 | [554] | -3.87[555] | [556] | -1.40[557] | 6.78[558] | 3.56[559] | 3.30[560] |
81 | ITGB6 | Integrin beta-6 | [561] | [562] | [563] | [564] | -1.91[565] | -4.58[566] | -2.90[567] |
82 | ITGAD | Integrin alpha-D | [568] | -5.41[569] | [570] | [571] | -5.73[572] | [573] | 3.33[574] |
83 | ITGB4 | Integrin beta-4 | [575] | 5.49[576] | 5.50[577] | 2.00[578] | 3.35[579] | 1.34[580] | 2.68[581] |
84 | PAK3 | Serine/threonine-protein kinase PAK 3 | [582] | -6.63[583] | [584] | [585] | -2.41[586] | -0.56[587] | 0.65[588] |
85 | ITGA9 | Integrin alpha-9 | [589] | -2.93[590] | -0.60[591] | -0.39[592] | -2.22[593] | -4.23[594] | 7.05[595] |
86 | PAK6 | Serine/threonine-protein kinase PAK 6 | [596] | -1.89[597] | [598] | 0.82[599] | 1.39[600] | 0.63[601] | -1.21[602] |
87 | ITGA10 | Integrin alpha-10 | [603] | 2.59[604] | 3.03[605] | -1.41[606] | 1.19[607] | 3.45[608] | 3.20[609] |
88 | SHC3 | SHC-transforming protein 3 | [610] | 1.89[611] | 4.21[612] | -3.24[613] | 2.64[614] | 6.68[615] | 1.69[616] |
89 | ITGA2B | Integrin alpha-IIb | [617] | 3.38[618] | 3.61[619] | 3.65[620] | 2.21[621] | 0.70[622] | 2.49[623] |
90 | ITGA8 | Integrin alpha-8 | [624] | [625] | -3.12[626] | -3.99[627] | 3.01[628] | [629] | 4.32[630] |
91 | ITGB8 | Integrin beta-8 | [631] | 2.04[632] | 1.49[633] | 5.64[634] | 4.73[635] | 5.77[636] | 6.61[637] |
92 | CAPN6 | Calpain-6 | [638] | [639] | [640] | [641] | 1.31[642] | [643] | 3.38[644] |
93 | MAPK10 | Mitogen-activated protein kinase 10 | [645] | -1.70[646] | [647] | [648] | 8.09[649] | 3.96[650] | 7.11[651] |
94 | SELENOP | Selenoprotein P | [652] | [653] | [654] | [655] | [656] | [657] | [658] |
95 | MIR6852 | [659] | [660] | [661] | [662] | [663] | [664] | [665] | |
96 | CAPN9 | Calpain-9 | [666] | [667] | [668] | [669] | [670] | [671] | [672] |
97 | CAPN11 | Calpain-11 | [673] | [674] | [675] | [676] | [677] | [678] | [679] |
98 | LINC02478 | [680] | [681] | [682] | [683] | [684] | [685] | [686] | |
99 | ITGA11 | Integrin alpha-11 | [687] | [688] | [689] | [690] | [691] | [692] | [693] |
100 | MYLK2 | Myosin light chain kinase 2, skeletal/cardiac muscle | [694] | [695] | [696] | [697] | [698] | [699] | [700] |
101 | BUB1B-PA | BUB1B-PAK6 readthrough (Fragment) | [701] | [702] | [703] | [704] | [705] | [706] | [707] |
102 | CAV3 | Caveolin-3 | [708] | [709] | [710] | [711] | [712] | [713] | [714] |
103 | RHO | Rhodopsin | [715] | [716] | [717] | [718] | [719] | [720] | [721] |
104 | MIR34C | [722] | [723] | [724] | [725] | [726] | [727] | [728] |