WP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H [1] -0.80[2] -0.27[3] -0.56[4] -0.90[5] -0.78[6] -0.33[7]
2 RAB5C Ras-related protein Rab-5C [8] 0.29[9] -0.84[10] -0.66[11] -0.49[12] -0.51[13] -1.30[14]
3 RRAS2 Ras-related protein R-Ras2 [15] -1.94[16] -1.74[17] -1.96[18] -1.52[19] -1.79[20] -1.69[21]
4 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate [22] 0.95[23] 0.50[24] -0.41[25] 0.54[26] 0.40[27] -0.67[28]
5 RAF1 RAF proto-oncogene serine/threonine-protein kinase [29] -0.01[30] 0.44[31] 1.32[32] -0.14[33] 0.67[34] 1.20[35]
6 NRAS GTPase NRas [36] 0.68[37] 1.16[38] 1.18[39] 1.04[40] 0.56[41] -0.15[42]
7 PDCD6IP Programmed cell death 6-interacting protein [43] 0.57[44] 0.60[45] 1.49[46] 0.93[47] 1.29[48] 1.18[49]
8 RRAS Ras-related protein R-Ras [50] -1.44[51] -2.37[52] -2.18[53] -0.24[54] -0.28[55] -2.08[56]
9 RAB5B Ras-related protein Rab-5B [57] 0.36[58] 1.25[59] 0.74[60] 1.11[61] 0.93[62] 0.96[63]
10 RAB5A Ras-related protein Rab-5A [64] -0.82[65] -0.60[66] 0.04[67] -0.19[68] 0.12[69] -0.09[70]
11 ARAF Serine/threonine-protein kinase A-Raf [71] -0.41[72] -0.67[73] -0.78[74] -0.05[75] -0.07[76] 0.98[77]
12 HRAS GTPase HRas [78] -0.96[79] -1.62[80] -2.79[81] -0.90[82] -1.18[83] -2.56[84]
13 MAPK1 Mitogen-activated protein kinase 1 [85] 1.76[86] 1.94[87] 1.39[88] 1.90[89] 1.49[90] 1.88[91]
14 KRAS GTPase KRas [92] -0.46[93] -0.44[94] 0.78[95] 0.85[96] 0.45[97] 0.78[98]
15 RAB27A Ras-related protein Rab-27A [99] -1.43[100] -0.78[101] -1.19[102] -0.42[103] 0.70[104] 0.75[105]
16 MAPK3 Mitogen-activated protein kinase 3 [106] 1.90[107] 1.99[108] 1.65[109] 0.47[110] 0.43[111] -0.94[112]
17 MRAS Ras-related protein M-Ras [113] 1.80[114] -3.82[115] -3.03[116] 0.50[117] 0.75[118] -1.56[119]
18 BRAF Serine/threonine-protein kinase B-raf [120] 0.30[121] 0.07[122] 1.72[123] 0.79[124] 0.42[125] 1.95[126]
[1]
ref_hepatocyte HNRNPH1
Mean 86.6
Standard deviation 73
Values 46 32 25 1.8e+02 1.5e+02
[2]
HepG2 HNRNPH1
Mean 106
Standard deviation 20
Values 1.2e+02 92
[3]
HepG2.C3A HNRNPH1
Mean 132
Standard deviation 11
Values 1.4e+02 1.2e+02
[4]
HuH.7 HNRNPH1
Mean 135
Standard deviation 34
Values 1.6e+02 98 1.4e+02
[5]
SNU475 HNRNPH1
Mean 82.2
Standard deviation 2
Values 84 81
[6]
THLE HNRNPH1
Mean 105
Standard deviation 12
Values 96 1.1e+02
[7]
liver HNRNPH1
Mean 91
Standard deviation 38
Values 55 69 1.4e+02 99
[8]
ref_hepatocyte RAB5C
Mean 53.9
Standard deviation 18
Values 57 29 45 74 64
[9]
HepG2 RAB5C
Mean 140
Standard deviation 1.1
Values 1.4e+02 1.4e+02
[10]
HepG2.C3A RAB5C
Mean 55.5
Standard deviation 14
Values 65 46
[11]
HuH.7 RAB5C
Mean 78.5
Standard deviation 17
Values 85 60 91
[12]
SNU475 RAB5C
Mean 68.4
Standard deviation 2.6
Values 67 70
[13]
THLE RAB5C
Mean 78.8
Standard deviation 9.9
Values 72 86
[14]
liver RAB5C
Mean 29
Standard deviation 14
Values 17 18 37 44
[15]
ref_hepatocyte RRAS2
Mean 32.8
Standard deviation 34
Values 39 14 9.3 11 90
[16]
HepG2 RRAS2
Mean 18.3
Standard deviation 1.2
Values 19 17
[17]
HepG2.C3A RRAS2
Mean 18
Standard deviation 1
Values 19 17
[18]
HuH.7 RRAS2
Mean 19.4
Standard deviation 2.9
Values 21 16 21
[19]
SNU475 RRAS2
Mean 20.4
Standard deviation 1.3
Values 19 21
[20]
THLE RRAS2
Mean 19.7
Standard deviation 2.8
Values 18 22
[21]
liver RRAS2
Mean 13.4
Standard deviation 2.9
Values 16 13 15 9.5
[22]
ref_hepatocyte HGS
Mean 16.6
Standard deviation 15
Values 42 8.1 11 6.9 15
[23]
HepG2 HGS
Mean 68.4
Standard deviation 17
Values 57 80
[24]
HepG2.C3A HGS
Mean 43.2
Standard deviation 8
Values 38 49
[25]
HuH.7 HGS
Mean 28.9
Standard deviation 4.1
Values 32 24 30
[26]
SNU475 HGS
Mean 43.1
Standard deviation 3.7
Values 46 40
[27]
THLE HGS
Mean 45.7
Standard deviation 2.6
Values 44 48
[28]
liver HGS
Mean 13.8
Standard deviation 3.3
Values 14 9.3 17 16
[29]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 20 17 20 6 14
[30]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 36 29
[31]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 37 41
[32]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 89 93 85
[33]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 28 22
[34]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[35]
liver RAF1
Mean 47
Standard deviation 3.6
Values 46 42 51 49
[36]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 9.3 4.6 3.3 32 23
[37]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 57 42
[38]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 72 47
[39]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 71 70 86
[40]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 46 59
[41]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[42]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 16 21 14 18
[43]
ref_hepatocyte PDCD6IP
Mean 13.1
Standard deviation 3.9
Values 15 9.8 8.4 15 18
[44]
HepG2 PDCD6IP
Mean 41.4
Standard deviation 9.9
Values 48 34
[45]
HepG2.C3A PDCD6IP
Mean 36.6
Standard deviation 0.5
Values 37 36
[46]
HuH.7 PDCD6IP
Mean 84.6
Standard deviation 5.9
Values 78 86 90
[47]
SNU475 PDCD6IP
Mean 44.3
Standard deviation 3.2
Values 42 47
[48]
THLE PDCD6IP
Mean 66.5
Standard deviation 4.9
Values 63 70
[49]
liver PDCD6IP
Mean 39.3
Standard deviation 4.8
Values 33 42 39 44
[50]
ref_hepatocyte RRAS
Mean 13
Standard deviation 11
Values 16 7.6 8.2 2.5 30
[51]
HepG2 RRAS
Mean 10.3
Standard deviation 5.7
Values 6.2 14
[52]
HepG2.C3A RRAS
Mean 4.63
Standard deviation 1.6
Values 3.5 5.8
[53]
HuH.7 RRAS
Mean 6.62
Standard deviation 0.43
Values 7.1 6.2 6.6
[54]
SNU475 RRAS
Mean 19.7
Standard deviation 4
Values 17 22
[55]
THLE RRAS
Mean 22.2
Standard deviation 0.93
Values 23 22
[56]
liver RRAS
Mean 4.07
Standard deviation 3.5
Values 1.3 0.8 7.4 6.8
[57]
ref_hepatocyte RAB5B
Mean 12.8
Standard deviation 1.3
Values 11 12 15 13 13
[58]
HepG2 RAB5B
Mean 35.2
Standard deviation 8.5
Values 41 29
[59]
HepG2.C3A RAB5B
Mean 56.2
Standard deviation 6.3
Values 52 61
[60]
HuH.7 RAB5B
Mean 49.2
Standard deviation 1.6
Values 48 51 49
[61]
SNU475 RAB5B
Mean 49.2
Standard deviation 17
Values 37 61
[62]
THLE RAB5B
Mean 50.8
Standard deviation 5.2
Values 47 54
[63]
liver RAB5B
Mean 33.1
Standard deviation 9
Values 26 27 33 46
[64]
ref_hepatocyte RAB5A
Mean 12.8
Standard deviation 4.6
Values 16 10 8.8 9.3 19
[65]
HepG2 RAB5A
Mean 15.4
Standard deviation 2.7
Values 17 13
[66]
HepG2.C3A RAB5A
Mean 15.5
Standard deviation 1.2
Values 15 16
[67]
HuH.7 RAB5A
Mean 30.3
Standard deviation 3.3
Values 27 34 30
[68]
SNU475 RAB5A
Mean 19.8
Standard deviation 0.012
Values 20 20
[69]
THLE RAB5A
Mean 28.9
Standard deviation 0.86
Values 28 29
[70]
liver RAB5A
Mean 15.9
Standard deviation 6.4
Values 9.6 11 22 21
[71]
ref_hepatocyte ARAF
Mean 12.3
Standard deviation 8
Values 13 19 21 4.1 4
[72]
HepG2 ARAF
Mean 19.8
Standard deviation 1.6
Values 19 21
[73]
HepG2.C3A ARAF
Mean 14.3
Standard deviation 2.2
Values 13 16
[74]
HuH.7 ARAF
Mean 16.5
Standard deviation 1.9
Values 17 14 18
[75]
SNU475 ARAF
Mean 21.1
Standard deviation 1.4
Values 20 22
[76]
THLE ARAF
Mean 24.2
Standard deviation 1.6
Values 23 25
[77]
liver ARAF
Mean 32.1
Standard deviation 23
Values 13 11 50 54
[78]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 11 8.8 7.4 4 27
[79]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 12 14
[80]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 7.9 6
[81]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 5.6 2.4 3.6
[82]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[83]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[84]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 1.4 1.1 4.1 3.8
[85]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[86]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[87]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[88]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[89]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[90]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[91]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[92]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 5.4 2.7 1.7 18 17
[93]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 16 12
[94]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 14 11
[95]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 36 30 40
[96]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 25 33
[97]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[98]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 14 16 33 19
[99]
ref_hepatocyte RAB27A
Mean 8.42
Standard deviation 6.1
Values 2.7 9.9 16 1.8 12
[100]
HepG2 RAB27A
Mean 6.65
Standard deviation 1.3
Values 7.6 5.7
[101]
HepG2.C3A RAB27A
Mean 9.02
Standard deviation 0.83
Values 9.6 8.4
[102]
HuH.7 RAB27A
Mean 8.52
Standard deviation 0.55
Values 8.7 7.9 9
[103]
SNU475 RAB27A
Mean 11.2
Standard deviation 3
Values 13 9.1
[104]
THLE RAB27A
Mean 28.3
Standard deviation 1.5
Values 29 27
[105]
liver RAB27A
Mean 18.7
Standard deviation 5.5
Values 12 17 24 22
[106]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[107]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[108]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[109]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[110]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[111]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[112]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[113]
ref_hepatocyte MRAS
Mean 3.26
Standard deviation 5.7
Values 0.42 0.15 0.41 13 2.1
[114]
HepG2 MRAS
Mean 24.2
Standard deviation 5.3
Values 28 21
[115]
HepG2.C3A MRAS
Mean 0.426
Standard deviation 0.066
Values 0.47 0.38
[116]
HuH.7 MRAS
Mean 0.918
Standard deviation 0.11
Values 0.8 1 0.94
[117]
SNU475 MRAS
Mean 8.2
Standard deviation 1.9
Values 6.9 9.5
[118]
THLE MRAS
Mean 11.4
Standard deviation 0.24
Values 11 12
[119]
liver MRAS
Mean 1.46
Standard deviation 0.22
Values 1.4 1.6 1.2 1.7
[120]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 2.3 0.67 0.67 0.56 1.2
[121]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 3.2 2.4
[122]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 2.5 1.6
[123]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 3.4 15 6.4
[124]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.4 3.2
[125]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[126]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 7.9 8 3.1 2.9