WP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GADD45A Growth arrest and DNA damage-inducible protein GADD45 alpha [1] -2.48[2] -3.49[3] -3.25[4] -3.03[5] -2.09[6] -2.87[7]
2 MYC Myc proto-oncogene protein [8] 0.42[9] 0.15[10] -1.83[11] -1.84[12] -0.26[13] -1.86[14]
3 CDKN1B Cyclin-dependent kinase inhibitor 1B [15] -0.09[16] 0.42[17] 0.66[18] -0.16[19] -0.48[20] -0.77[21]
4 ABCB1 Multidrug resistance protein 1 [22] -0.59[23] 0.99[24] -0.58[25] -4.90[26] -7.36[27] 0.82[28]
5 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase [29] 0.81[30] 0.50[31] 0.60[32] 0.61[33] 0.55[34] -0.76[35]
6 PIM1 Serine/threonine-protein kinase pim-1 [36] 0.18[37] 0.02[38] -0.57[39] 1.34[40] -0.47[41] -0.99[42]
7 ABL1 Tyrosine-protein kinase ABL1 [43] 2.22[44] 1.68[45] 2.52[46] 3.02[47] 2.92[48] 1.08[49]
8 BCR Breakpoint cluster region protein [50] 2.22[51] 1.54[52] 1.83[53] 1.97[54] 1.56[55] 1.84[56]
9 SKP2 S-phase kinase-associated protein 2 [57] 1.30[58] 1.83[59] 3.01[60] 2.21[61] 1.51[62] 1.22[63]
10 PIM2 Serine/threonine-protein kinase pim-2 [64] -0.41[65] 0.17[66] 0.74[67] 0.26[68] -0.21[69] -0.24[70]
11 ABCG2 ATP-binding cassette sub-family G member 2 [71] 0.05[72] 0.00[73] 1.19[74] 0.60[75] -1.30[76] 0.41[77]
12 FOXO3 Forkhead box protein O3 [78] 0.45[79] 0.61[80] 1.29[81] 1.35[82] 1.80[83] 2.47[84]
13 SPRED2 Sprouty-related, EVH1 domain-containing protein 2 [85] 2.08[86] 2.40[87] 2.21[88] 2.10[89] 1.71[90] 1.05[91]
14 GAB2 GRB2-associated-binding protein 2 [92] 1.56[93] 1.41[94] 1.70[95] 1.88[96] 1.17[97] 0.68[98]
15 CSF1R Macrophage colony-stimulating factor 1 receptor [99] -6.31[100] -9.17[101] -7.78[102] 0.71[103] -4.71[104] 2.83[105]
16 PDGFRA Platelet-derived growth factor receptor alpha [106] -3.63[107] -4.54[108] 3.14[109] 1.48[110] 5.36[111] 5.46[112]
17 PDGFRB Platelet-derived growth factor receptor beta [113] 1.29[114] 1.76[115] -0.65[116] 2.81[117] 2.58[118] 3.55[119]
18 FLT1 Vascular endothelial growth factor receptor 1 [120] -1.52[121] -1.08[122] -1.47[123] 0.66[124] -1.07[125] 6.23[126]
19 LYL1 Protein lyl-1 [127] 1.14[128] 1.55[129] 1.89[130] 0.06[131] 1.39[132] 0.76[133]
20 KIT Mast/stem cell growth factor receptor Kit [134] -3.00[135] -4.81[136] [137] 3.45[138] -2.87[139] 3.78[140]
21 MIR1204 [141] [142] [143] [144] [145] [146] [147]
[1]
ref_hepatocyte GADD45A
Mean 72.7
Standard deviation 61
Values 1.2e+02 36 23 28 1.5e+02
[2]
HepG2 GADD45A
Mean 29
Standard deviation 18
Values 16 42
[3]
HepG2.C3A GADD45A
Mean 12.2
Standard deviation 0.97
Values 12 13
[4]
HuH.7 GADD45A
Mean 13.4
Standard deviation 4.4
Values 13 18 9.2
[5]
SNU475 GADD45A
Mean 8.43
Standard deviation 3
Values 11 6.3
[6]
THLE GADD45A
Mean 31.4
Standard deviation 0.034
Values 31 31
[7]
liver GADD45A
Mean 12.8
Standard deviation 5.7
Values 11 5.8 15 19
[8]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 89 1.4 23 15 20
[9]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 52 1.3e+02
[10]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 52 73
[11]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 14 18 13
[12]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 8.9 6.9
[13]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[14]
liver MYC
Mean 10.6
Standard deviation 6
Values 5.5 5.9 18 13
[15]
ref_hepatocyte CDKN1B
Mean 13.8
Standard deviation 6
Values 7.5 15 10 23 13
[16]
HepG2 CDKN1B
Mean 28.7
Standard deviation 3.4
Values 26 31
[17]
HepG2.C3A CDKN1B
Mean 34.7
Standard deviation 1.4
Values 36 34
[18]
HuH.7 CDKN1B
Mean 38.2
Standard deviation 3.7
Values 37 42 35
[19]
SNU475 CDKN1B
Mean 11.8
Standard deviation 2.9
Values 9.7 14
[20]
THLE CDKN1B
Mean 18.2
Standard deviation 3.4
Values 16 21
[21]
liver CDKN1B
Mean 10.5
Standard deviation 3.5
Values 12 14 9.9 5.8
[22]
ref_hepatocyte ABCB1
Mean 12.8
Standard deviation 7
Values 15 5.6 5.4 17 21
[23]
HepG2 ABCB1
Mean 18.8
Standard deviation 3.2
Values 21 17
[24]
HepG2.C3A ABCB1
Mean 47.9
Standard deviation 1.3
Values 49 47
[25]
HuH.7 ABCB1
Mean 15
Standard deviation 8.7
Values 9 25 11
[26]
SNU475 ABCB1
Mean 0.405
Standard deviation 0.094
Values 0.47 0.34
[27]
THLE ABCB1
Mean 0.143
Standard deviation 0.0068
Values 0.15 0.14
[28]
liver ABCB1
Mean 29
Standard deviation 14
Values 31 46 13 26
[29]
ref_hepatocyte NOP2
Mean 11.9
Standard deviation 5.9
Values 18 2.9 10 12 16
[30]
HepG2 NOP2
Mean 46.4
Standard deviation 4.1
Values 43 49
[31]
HepG2.C3A NOP2
Mean 31.8
Standard deviation 1.8
Values 33 30
[32]
HuH.7 NOP2
Mean 31.6
Standard deviation 9
Values 40 22 33
[33]
SNU475 NOP2
Mean 17.3
Standard deviation 5.5
Values 21 13
[34]
THLE NOP2
Mean 32.1
Standard deviation 0.45
Values 32 32
[35]
liver NOP2
Mean 9.13
Standard deviation 4.5
Values 5.9 5.2 11 15
[36]
ref_hepatocyte PIM1
Mean 9.92
Standard deviation 7.8
Values 13 6.7 22 6.1 2
[37]
HepG2 PIM1
Mean 25
Standard deviation 18
Values 12 38
[38]
HepG2.C3A PIM1
Mean 19
Standard deviation 15
Values 8.7 29
[39]
HuH.7 PIM1
Mean 11.7
Standard deviation 6.4
Values 7.9 19 8.2
[40]
SNU475 PIM1
Mean 23.8
Standard deviation 9.3
Values 17 30
[41]
THLE PIM1
Mean 13.2
Standard deviation 2.3
Values 12 15
[42]
liver PIM1
Mean 6.47
Standard deviation 0.83
Values 7.5 5.4 6.6 6.4
[43]
ref_hepatocyte ABL1
Mean 3.99
Standard deviation 2.5
Values 8 2 1.7 4.1 4.1
[44]
HepG2 ABL1
Mean 41.3
Standard deviation 2.2
Values 40 43
[45]
HepG2.C3A ABL1
Mean 24.2
Standard deviation 1.3
Values 25 23
[46]
HuH.7 ABL1
Mean 40.3
Standard deviation 6.6
Values 35 38 48
[47]
SNU475 ABL1
Mean 30.8
Standard deviation 0.67
Values 30 31
[48]
THLE ABL1
Mean 55.5
Standard deviation 15
Values 45 66
[49]
liver ABL1
Mean 10.9
Standard deviation 3.5
Values 14 13 8.1 7.7
[50]
ref_hepatocyte BCR
Mean 3.7
Standard deviation 0.66
Values 3.6 2.9 3.9 3.5 4.7
[51]
HepG2 BCR
Mean 38.2
Standard deviation 4.3
Values 35 41
[52]
HepG2.C3A BCR
Mean 20.2
Standard deviation 1.8
Values 19 22
[53]
HuH.7 BCR
Mean 23.1
Standard deviation 5.7
Values 22 18 29
[54]
SNU475 BCR
Mean 13.8
Standard deviation 3.1
Values 12 16
[55]
THLE BCR
Mean 20
Standard deviation 5.2
Values 16 24
[56]
liver BCR
Mean 17.1
Standard deviation 6.7
Values 23 22 12 11
[57]
ref_hepatocyte SKP2
Mean 3.55
Standard deviation 2.3
Values 2 4.2 2.1 7.4 2.1
[58]
HepG2 SKP2
Mean 19.5
Standard deviation 10
Values 27 12
[59]
HepG2.C3A SKP2
Mean 23.9
Standard deviation 9.3
Values 30 17
[60]
HuH.7 SKP2
Mean 50.3
Standard deviation 8.4
Values 55 41 55
[61]
SNU475 SKP2
Mean 15.6
Standard deviation 5.3
Values 12 19
[62]
THLE SKP2
Mean 18.6
Standard deviation 0.58
Values 19 18
[63]
liver SKP2
Mean 10.7
Standard deviation 2.5
Values 13 12 8.2 8.9
[64]
ref_hepatocyte PIM2
Mean 3.45
Standard deviation 2.7
Values 5.4 6.7 3.5 0.54 1.1
[65]
HepG2 PIM2
Mean 5.75
Standard deviation 0.88
Values 6.4 5.1
[66]
HepG2.C3A PIM2
Mean 7.34
Standard deviation 1.1
Values 6.6 8.1
[67]
HuH.7 PIM2
Mean 10.1
Standard deviation 1.3
Values 11 8.5 11
[68]
SNU475 PIM2
Mean 3.93
Standard deviation 0.4
Values 3.6 4.2
[69]
THLE PIM2
Mean 5.5
Standard deviation 0.22
Values 5.3 5.7
[70]
liver PIM2
Mean 3.77
Standard deviation 2.6
Values 1.7 1.5 6.9 4.9
[71]
ref_hepatocyte ABCG2
Mean 3
Standard deviation 1.8
Values 2.9 4.4 1.5 1.1 5.2
[72]
HepG2 ABCG2
Mean 6.88
Standard deviation 0.34
Values 6.6 7.1
[73]
HepG2.C3A ABCG2
Mean 5.65
Standard deviation 0.97
Values 6.3 5
[74]
HuH.7 ABCG2
Mean 11.9
Standard deviation 1.2
Values 11 11 13
[75]
SNU475 ABCG2
Mean 4.32
Standard deviation 1
Values 5 3.6
[76]
THLE ABCG2
Mean 2.24
Standard deviation 1.1
Values 1.4 3
[77]
liver ABCG2
Mean 5.14
Standard deviation 1.6
Values 5 7.3 3.4 4.8
[78]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 2.3 2.9 2.8 3.3 2.7
[79]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 9.2 7.7
[80]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 6.3 9.7
[81]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 7.9 15 13
[82]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 6.2 7.3
[83]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[84]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 23 21 24 12
[85]
ref_hepatocyte SPRED2
Mean 2.72
Standard deviation 1.4
Values 4.9 2.3 3.2 1.2 2.1
[86]
HepG2 SPRED2
Mean 25.5
Standard deviation 1.3
Values 26 25
[87]
HepG2.C3A SPRED2
Mean 27
Standard deviation 5
Values 23 31
[88]
HuH.7 SPRED2
Mean 22
Standard deviation 5.4
Values 21 17 28
[89]
SNU475 SPRED2
Mean 11.1
Standard deviation 5.1
Values 15 7.4
[90]
THLE SPRED2
Mean 16.4
Standard deviation 2.1
Values 15 18
[91]
liver SPRED2
Mean 7.3
Standard deviation 3.7
Values 5.3 4.5 13 6.7
[92]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 4.5 0.31 0.25 1.2 1.9
[93]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 7.1 14
[94]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 5.9 10
[95]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 6.6 12 9.6
[96]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 5.1 6.1
[97]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[98]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 4.6 4.2 2.8 1.8
[99]
ref_hepatocyte CSF1R
Mean 1.48
Standard deviation 1.9
Values 0.48 4.2 2.6 0 0.088
[100]
HepG2 CSF1R
Mean 0.0415
Standard deviation 0.047
Values 0.0086 0.074
[101]
HepG2.C3A CSF1R
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[102]
HuH.7 CSF1R
Mean 0.0119
Standard deviation 0.01
Values 0 0.019 0.016
[103]
SNU475 CSF1R
Mean 2.31
Standard deviation 1.6
Values 3.5 1.2
[104]
THLE CSF1R
Mean 0.105
Standard deviation 0.028
Values 0.12 0.085
[105]
liver CSF1R
Mean 13.6
Standard deviation 3.9
Values 18 15 8.8 13
[106]
ref_hepatocyte PDGFRA
Mean 0.51
Standard deviation 0.67
Values 1.5 0.11 0.93 0 0.018
[107]
HepG2 PDGFRA
Mean 0.0916
Standard deviation 0.016
Values 0.1 0.08
[108]
HepG2.C3A PDGFRA
Mean 0.0414
Standard deviation 0.017
Values 0.054 0.029
[109]
HuH.7 PDGFRA
Mean 7.89
Standard deviation 0.88
Values 6.9 8.5 8.3
[110]
SNU475 PDGFRA
Mean 1.35
Standard deviation 1.4
Values 2.3 0.38
[111]
THLE PDGFRA
Mean 38.6
Standard deviation 7.6
Values 33 44
[112]
liver PDGFRA
Mean 28.9
Standard deviation 13
Values 43 35 23 15
[113]
ref_hepatocyte PDGFRB
Mean 0.484
Standard deviation 0.34
Values 0.58 0.51 0.98 0.12 0.23
[114]
HepG2 PDGFRB
Mean 2.63
Standard deviation 0.88
Values 3.3 2
[115]
HepG2.C3A PDGFRB
Mean 3.08
Standard deviation 0.099
Values 3.2 3
[116]
HuH.7 PDGFRB
Mean 0.54
Standard deviation 0.088
Values 0.44 0.57 0.61
[117]
SNU475 PDGFRB
Mean 3.21
Standard deviation 0.1
Values 3.3 3.1
[118]
THLE PDGFRB
Mean 5.3
Standard deviation 0.27
Values 5.1 5.5
[119]
liver PDGFRB
Mean 7.32
Standard deviation 2
Values 10 6.3 6.9 5.8
[120]
ref_hepatocyte FLT1
Mean 0.232
Standard deviation 0.18
Values 0.38 0.37 0.33 0 0.085
[121]
HepG2 FLT1
Mean 0.18
Standard deviation 0.0053
Values 0.18 0.18
[122]
HepG2.C3A FLT1
Mean 0.206
Standard deviation 0.072
Values 0.26 0.16
[123]
HuH.7 FLT1
Mean 0.146
Standard deviation 0.035
Values 0.12 0.19 0.13
[124]
SNU475 FLT1
Mean 0.348
Standard deviation 0.21
Values 0.5 0.2
[125]
THLE FLT1
Mean 0.204
Standard deviation 0.02
Values 0.19 0.22
[126]
liver FLT1
Mean 22.6
Standard deviation 10
Values 22 37 14 17
[127]
ref_hepatocyte LYL1
Mean 0.207
Standard deviation 0.25
Values 0 0.59 0.32 0 0.13
[128]
HepG2 LYL1
Mean 1.02
Standard deviation 0.39
Values 0.74 1.3
[129]
HepG2.C3A LYL1
Mean 1.14
Standard deviation 0.036
Values 1.1 1.2
[130]
HuH.7 LYL1
Mean 1.35
Standard deviation 0.18
Values 1.5 1.1 1.4
[131]
SNU475 LYL1
Mean 0.205
Standard deviation 0.13
Values 0.3 0.11
[132]
THLE LYL1
Mean 0.997
Standard deviation 0.0036
Values 1 0.99
[133]
liver LYL1
Mean 0.455
Standard deviation 0.15
Values 0.56 0.51 0.24 0.51
[134]
ref_hepatocyte KIT
Mean 0.0798
Standard deviation 0.075
Values 0.15 0.15 0.1 0 0
[135]
HepG2 KIT
Mean 0.0222
Standard deviation 0.025
Values 0.0043 0.04
[136]
HepG2.C3A KIT
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[137]
HuH.7 KIT
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 KIT
Mean 0.83
Standard deviation 0.64
Values 0.38 1.3
[139]
THLE KIT
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[140]
liver KIT
Mean 1.41
Standard deviation 1.3
Values 0.54 3 0.21 1.9
[141]
ref_hepatocyte MIR1204
Missing
[142]
HepG2 MIR1204
Missing
[143]
HepG2.C3A MIR1204
Missing
[144]
HuH.7 MIR1204
Missing
[145]
SNU475 MIR1204
Missing
[146]
THLE MIR1204
Missing
[147]
liver MIR1204
Missing