WP_IL9_SIGNALING_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STAT3 Signal transducer and activator of transcription 3 [1] 0.03[2] -1.18[3] -0.82[4] -0.64[5] -0.88[6] 1.25[7]
2 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [8] -1.45[9] -1.49[10] -1.29[11] -1.43[12] -0.43[13] -2.35[14]
3 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [15] -0.47[16] -0.50[17] -0.01[18] -1.73[19] -0.75[20] -2.86[21]
4 GRB2 Growth factor receptor-bound protein 2 [22] 0.67[23] 0.80[24] 0.54[25] -0.33[26] 0.08[27] -0.86[28]
5 STAT1 Signal transducer and activator of transcription 1-alpha/beta [29] -0.60[30] -1.22[31] -0.49[32] 1.65[33] -0.13[34] -0.21[35]
6 JAK1 Tyrosine-protein kinase JAK1 [36] -0.01[37] -0.23[38] -0.43[39] -0.26[40] 0.88[41] 0.37[42]
7 CDK9 Cyclin-dependent kinase 9 [43] -0.90[44] -0.97[45] -1.27[46] -1.04[47] -0.84[48] -1.01[49]
8 MAPK1 Mitogen-activated protein kinase 1 [50] 1.19[51] 1.62[52] 1.07[53] 0.96[54] 1.11[55] 0.62[56]
9 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [57] -0.99[58] -0.59[59] 0.13[60] 1.18[61] 1.18[62] 1.84[63]
10 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [64] 1.35[65] 1.87[66] 2.10[67] -0.18[68] 0.87[69] -1.45[70]
11 MAPK3 Mitogen-activated protein kinase 3 [71] 1.33[72] 1.66[73] 1.33[74] -0.46[75] 0.05[76] -2.20[77]
12 STAT5B Signal transducer and activator of transcription 5B [78] 0.83[79] 0.75[80] 1.08[81] 0.67[82] 0.30[83] 0.46[84]
13 STAT5A Signal transducer and activator of transcription 5A [85] -2.47[86] -1.00[87] -2.31[88] -1.73[89] -0.48[90] -0.92[91]
14 IL2RG Cytokine receptor common subunit gamma [92] -2.17[93] -3.77[94] -3.50[95] -4.48[96] [97] -1.27[98]
15 JAK3 Tyrosine-protein kinase JAK3 [99] 1.72[100] 4.29[101] -2.10[102] -1.52[103] -0.29[104] 1.94[105]
16 IL9R Interleukin-9 receptor [106] [107] [108] [109] [110] [111] [112]
17 MIR3960 [113] [114] [115] [116] [117] [118] [119]
18 MIR2861 [120] [121] [122] [123] [124] [125] [126]
19 IL9 Interleukin-9 [127] [128] [129] [130] [131] [132] [133]
[1]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[2]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[3]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[4]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[5]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[6]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[7]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[8]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 32 27 15 27 39
[9]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 30 35
[10]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[11]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 40 27 33
[12]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 39 32
[13]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[14]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 12 11 28 18
[15]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[16]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[17]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[18]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[19]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[20]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[21]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[22]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 20 17 14 27 26
[23]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1.1e+02 1e+02
[24]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[25]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 93 78 89
[26]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 57 55
[27]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[28]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 22 50 50
[29]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 19 18 12 17 35
[30]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 49 36
[31]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 25 15
[32]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 40 38 47
[33]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 1.1e+02 3.2e+02
[34]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[35]
liver STAT1
Mean 55.8
Standard deviation 15
Values 38 69 49 67
[36]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 18 10 14 6.8 27
[37]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 56 40
[38]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 29 31
[39]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 29 32 36
[40]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 39 47
[41]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[42]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 62 75 54 58
[43]
ref_hepatocyte CDK9
Mean 12.2
Standard deviation 3.1
Values 11 10 14 8.9 17
[44]
HepG2 CDK9
Mean 20.8
Standard deviation 3.7
Values 18 23
[45]
HepG2.C3A CDK9
Mean 14.3
Standard deviation 1.4
Values 13 15
[46]
HuH.7 CDK9
Mean 14.6
Standard deviation 2.2
Values 16 12 16
[47]
SNU475 CDK9
Mean 20.1
Standard deviation 0.34
Values 20 20
[48]
THLE CDK9
Mean 18.3
Standard deviation 4.1
Values 15 21
[49]
liver CDK9
Mean 19.2
Standard deviation 2.9
Values 16 18 21 22
[50]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[51]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[52]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[53]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[54]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[55]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[56]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[57]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.2 14 8.1 4.1 7.4
[58]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 14 9.8
[59]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 13 9.6
[60]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 15 32 23
[61]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 35 80
[62]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[63]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1.4e+02 1e+02 64 32
[64]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 3.1 3.8 4.9 11 3.2
[65]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 41 44
[66]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 35 53
[67]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 64 55 75
[68]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 13 18
[69]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[70]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6.9 6 7.6 3.8
[71]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[72]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[73]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[74]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[75]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[76]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[77]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[78]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 2.3 5.6 4.6 4.1 3.3
[79]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 18 27
[80]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 13 18
[81]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 26 22 25
[82]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 19 24
[83]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[84]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 22 21 13 14
[85]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 5 0.95 1.5 1.8 2.7
[86]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.3 1.4
[87]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.9 2.6
[88]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.2 1.8 1.1
[89]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.3 2.5
[90]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[91]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 6.2 3.5 3 3.3
[92]
ref_hepatocyte IL2RG
Mean 1.04
Standard deviation 1.2
Values 0.89 3 1.3 0 0
[93]
HepG2 IL2RG
Mean 0.733
Standard deviation 0.88
Values 0.11 1.4
[94]
HepG2.C3A IL2RG
Mean 0.176
Standard deviation 0.067
Values 0.13 0.22
[95]
HuH.7 IL2RG
Mean 0.264
Standard deviation 0.039
Values 0.31 0.24 0.25
[96]
SNU475 IL2RG
Mean 0.158
Standard deviation 0.092
Values 0.22 0.093
[97]
THLE IL2RG
Mean 0
Standard deviation 0
Values 0 0
[98]
liver IL2RG
Mean 1.37
Standard deviation 1.1
Values 0.41 0.51 2.4 2.2
[99]
ref_hepatocyte JAK3
Mean 0.235
Standard deviation 0.23
Values 0.15 0.31 0.078 0.61 0.026
[100]
HepG2 JAK3
Mean 2.46
Standard deviation 0.35
Values 2.2 2.7
[101]
HepG2.C3A JAK3
Mean 10.6
Standard deviation 4.3
Values 7.6 14
[102]
HuH.7 JAK3
Mean 0.158
Standard deviation 0.069
Values 0.12 0.24 0.11
[103]
SNU475 JAK3
Mean 0.279
Standard deviation 0.0072
Values 0.28 0.27
[104]
THLE JAK3
Mean 0.519
Standard deviation 0.094
Values 0.59 0.45
[105]
liver JAK3
Mean 2.86
Standard deviation 0.73
Values 3.9 2.2 2.8 2.5
[106]
ref_hepatocyte IL9R
Mean 0.0397
Standard deviation 0.089
Values 0 0 0.2 0 0
[107]
HepG2 IL9R
Missing
[108]
HepG2.C3A IL9R
Missing
[109]
HuH.7 IL9R
Missing
[110]
SNU475 IL9R
Missing
[111]
THLE IL9R
Missing
[112]
liver IL9R
Missing
[113]
ref_hepatocyte MIR3960
Missing
[114]
HepG2 MIR3960
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A MIR3960
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[116]
HuH.7 MIR3960
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 MIR3960
Mean 0.012
Standard deviation 0.0027
Values 0.01 0.014
[118]
THLE MIR3960
Mean 0
Standard deviation 0
Values 0 0
[119]
liver MIR3960
Mean 0
Standard deviation 0
Values 0 0 0 0
[120]
ref_hepatocyte MIR2861
Missing
[121]
HepG2 MIR2861
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[122]
HepG2.C3A MIR2861
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[123]
HuH.7 MIR2861
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 MIR2861
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[125]
THLE MIR2861
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[126]
liver MIR2861
Mean 0.00588
Standard deviation 0.012
Values 0 0 0.024 0
[127]
ref_hepatocyte IL9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 IL9
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A IL9
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 IL9
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 IL9
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[132]
THLE IL9
Mean 0
Standard deviation 0
Values 0 0
[133]
liver IL9
Mean 0
Standard deviation 0
Values 0 0 0 0