WP_IL6_SIGNALING_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CRP C-reactive protein [1] [2] [3] -14.71[4] [5] -14.58[6] -0.44[7]
2 AGT Angiotensinogen [8] 0.57[9] 1.43[10] -0.14[11] -4.22[12] -9.32[13] 1.39[14]
3 TIMP1 Metalloproteinase inhibitor 1 [15] 0.18[16] -1.55[17] -8.70[18] 0.42[19] 1.97[20] -0.51[21]
4 RAC1 Ras-related C3 botulinum toxin substrate 1 [22] 2.01[23] 1.58[24] 2.31[25] 2.40[26] 2.35[27] -1.43[28]
5 JUNB Transcription factor jun-B [29] 0.45[30] -0.52[31] 0.22[32] 0.22[33] 1.03[34] -1.85[35]
6 AKT1 RAC-alpha serine/threonine-protein kinase [36] 2.48[37] 2.15[38] 1.09[39] 2.33[40] 2.33[41] -0.71[42]
7 STAT3 Signal transducer and activator of transcription 3 [43] 2.95[44] 1.36[45] 2.12[46] 2.63[47] 1.87[48] 1.94[49]
8 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [50] 1.47[51] 1.05[52] 1.65[53] 1.84[54] 2.32[55] -1.66[56]
9 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [57] 2.46[58] 2.04[59] 2.93[60] 1.54[61] 2.00[62] -2.17[63]
10 BCL2L1 Bcl-2-like protein 1 [64] 4.54[65] 3.83[66] 4.81[67] 1.77[68] 2.13[69] -1.28[70]
11 NR2F6 Nuclear receptor subfamily 2 group F member 6 [71] 1.90[72] 1.56[73] 2.54[74] 0.93[75] 0.64[76] -0.69[77]
12 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [78] 2.85[79] 3.18[80] 3.16[81] 3.27[82] 3.88[83] 0.79[84]
13 HDAC1 Histone deacetylase 1 [85] 2.91[86] 2.83[87] 3.53[88] 3.03[89] 2.79[90] -0.93[91]
14 GRB2 Growth factor receptor-bound protein 2 [92] 3.60[93] 3.34[94] 3.48[95] 2.94[96] 2.82[97] -0.17[98]
15 STAT1 Signal transducer and activator of transcription 1-alpha/beta [99] 2.33[100] 1.31[101] 2.44[102] 4.92[103] 2.62[104] 0.49[105]
16 BAD Bcl2-associated agonist of cell death [106] 0.73[107] 0.76[108] -0.16[109] 1.32[110] 1.69[111] -1.88[112]
17 SHC1 SHC-transforming protein 1 [113] 3.57[114] 3.69[115] 3.78[116] 5.04[117] 4.49[118] 0.31[119]
18 IL6ST Interleukin-6 receptor subunit beta [120] 2.66[121] 3.81[122] 3.36[123] 4.11[124] 5.25[125] 3.31[126]
19 JAK1 Tyrosine-protein kinase JAK1 [127] 2.92[128] 2.30[129] 2.51[130] 3.01[131] 3.63[132] 1.07[133]
20 SOCS3 Suppressor of cytokine signaling 3 [134] -1.74[135] -2.25[136] -0.51[137] 1.59[138] 0.48[139] -0.33[140]
21 MAPK1 Mitogen-activated protein kinase 1 [141] 4.11[142] 4.15[143] 4.00[144] 4.23[145] 3.85[146] 1.31[147]
22 IL6R Interleukin-6 receptor subunit alpha [148] 2.19[149] 2.41[150] 1.61[151] 1.51[152] -2.62[153] 1.19[154]
23 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 [155] 2.30[156] 3.28[157] 3.17[158] 2.87[159] 3.03[160] -0.22[161]
24 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [162] 1.93[163] 1.95[164] 3.06[165] 4.45[166] 3.92[167] 2.54[168]
25 SOS1 Son of sevenless homolog 1 [169] 2.30[170] 3.73[171] 3.26[172] 3.23[173] 2.43[174] 0.07[175]
26 IRF1 Interferon regulatory factor 1 [176] 1.89[177] 1.33[178] 1.49[179] 3.64[180] 2.61[181] 0.37[182]
27 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [183] 4.28[184] 4.40[185] 5.03[186] 3.09[187] 3.62[188] -0.76[189]
28 MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 [190] 3.11[191] 3.64[192] 2.86[193] 3.59[194] 2.96[195] 0.60[196]
29 TYK2 Non-receptor tyrosine-protein kinase TYK2 [197] 3.54[198] 3.80[199] 3.95[200] 3.13[201] 4.03[202] 1.52[203]
30 MAPK3 Mitogen-activated protein kinase 3 [204] 4.25[205] 4.20[206] 4.26[207] 2.81[208] 2.80[209] -1.50[210]
31 GSK3B Glycogen synthase kinase-3 beta [211] 3.67[212] 3.21[213] 3.80[214] 4.20[215] 4.00[216] 0.70[217]
32 PRKCD Protein kinase C delta type [218] 3.50[219] 3.65[220] 3.15[221] 1.88[222] 3.01[223] -1.53[224]
33 RPS6KB1 Ribosomal protein S6 kinase beta-1 [225] [226] [227] [228] [229] [230] [231]
34 NLK Serine/threonine-protein kinase NLK [232] 2.68[233] 3.14[234] 3.66[235] 3.10[236] 2.83[237] 0.35[238]
35 NCOA1 Nuclear receptor coactivator 1 [239] 2.87[240] 3.34[241] 3.55[242] 4.18[243] 3.60[244] 2.19[245]
36 CREBBP CREB-binding protein [246] 5.30[247] 4.42[248] 5.05[249] 5.14[250] 5.12[251] 2.77[252]
37 HCK Tyrosine-protein kinase HCK [253] -3.44[254] -3.72[255] [256] -2.88[257] -3.85[258] 0.24[259]
38 IL6 Interleukin-6 [260] -6.04[261] [262] -2.51[263] 1.53[264] 4.02[265] [266]
39 GAB1 GRB2-associated-binding protein 1 [267] 3.70[268] 4.69[269] 4.84[270] 4.32[271] 4.15[272] 2.41[273]
40 JAK2 Tyrosine-protein kinase JAK2 [274] 2.63[275] 2.53[276] 2.10[277] 3.15[278] 3.71[279] 2.24[280]
41 VAV1 Proto-oncogene vav [281] -6.09[282] -1.36[283] -3.05[284] -3.70[285] -4.99[286] 0.72[287]
42 PRDM1 PR domain zinc finger protein 1 [288] -1.41[289] -3.34[290] 3.76[291] 5.74[292] 3.40[293] 2.90[294]
43 VIP VIP peptides [295] 1.41[296] 1.35[297] [298] 2.71[299] 0.64[300] 1.20[301]
[1]
ref_hepatocyte CRP
Mean 3.33e+03
Standard deviation 5.7e+03
Values 7.6e+02 2.4e+03 1.3e+04 0 4.8
[2]
HepG2 CRP
Mean 0
Standard deviation 0
Values 0 0
[3]
HepG2.C3A CRP
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 CRP
Mean 0.0466
Standard deviation 0.01
Values 0.037 0.045 0.057
[5]
SNU475 CRP
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE CRP
Mean 0.0547
Standard deviation 0.04
Values 0.083 0.027
[7]
liver CRP
Mean 4.8e+03
Standard deviation 4.3e+03
Values 1.6e+03 3.6e+03 2.9e+03 1.1e+04
[8]
ref_hepatocyte AGT
Mean 439
Standard deviation 4.5e+02
Values 77 7e+02 1.1e+03 3.3e+02 6.7
[9]
HepG2 AGT
Mean 273
Standard deviation 17
Values 2.9e+02 2.6e+02
[10]
HepG2.C3A AGT
Mean 471
Standard deviation 99
Values 4e+02 5.4e+02
[11]
HuH.7 AGT
Mean 150
Standard deviation 28
Values 1.4e+02 1.8e+02 1.3e+02
[12]
SNU475 AGT
Mean 8.25
Standard deviation 2.2
Values 9.8 6.7
[13]
THLE AGT
Mean 0.276
Standard deviation 0.11
Values 0.35 0.2
[14]
liver AGT
Mean 2.25e+03
Standard deviation 2.3e+03
Values 6.1e+02 6.9e+02 5.5e+03 2.2e+03
[15]
ref_hepatocyte TIMP1
Mean 124
Standard deviation 1.5e+02
Values 2e+02 61 3.5e+02 1 7.3
[16]
HepG2 TIMP1
Mean 58.4
Standard deviation 10
Values 66 51
[17]
HepG2.C3A TIMP1
Mean 16.9
Standard deviation 5.3
Values 21 13
[18]
HuH.7 TIMP1
Mean 0.112
Standard deviation 0.04
Values 0.075 0.15 0.11
[19]
SNU475 TIMP1
Mean 58.3
Standard deviation 15
Values 69 48
[20]
THLE TIMP1
Mean 195
Standard deviation 24
Values 2.1e+02 1.8e+02
[21]
liver TIMP1
Mean 170
Standard deviation 2.5e+02
Values 9.9 7.4 5.3e+02 1.3e+02
[22]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 81 47 45 28 59
[23]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 86 89
[24]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 57 67
[25]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[26]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 1e+02 89
[27]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[28]
liver RAC1
Mean 37.8
Standard deviation 32
Values 9.5 12 63 67
[29]
ref_hepatocyte JUNB
Mean 38
Standard deviation 34
Values 61 31 84 4.3 9.7
[30]
HepG2 JUNB
Mean 21.6
Standard deviation 12
Values 13 30
[31]
HepG2.C3A JUNB
Mean 10.6
Standard deviation 6.5
Values 6 15
[32]
HuH.7 JUNB
Mean 16.6
Standard deviation 6.7
Values 14 24 12
[33]
SNU475 JUNB
Mean 15.5
Standard deviation 3.7
Values 18 13
[34]
THLE JUNB
Mean 31.2
Standard deviation 6
Values 27 35
[35]
liver JUNB
Mean 20.6
Standard deviation 9
Values 28 18 28 9.1
[36]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[37]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[38]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[39]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[40]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[41]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[42]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[43]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[44]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[45]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[46]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[47]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[48]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[49]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[50]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 32 27 15 27 39
[51]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 30 35
[52]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[53]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 40 27 33
[54]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 39 32
[55]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[56]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 12 11 28 18
[57]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[58]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[59]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[60]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[61]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[62]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[63]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[64]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 34 16 23 16 44
[65]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 2.2e+02 3e+02
[66]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[67]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.2e+02 2.1e+02 3.1e+02
[68]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 35 29
[69]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[70]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 14 9.8 31 31
[71]
ref_hepatocyte NR2F6
Mean 23.6
Standard deviation 16
Values 10 40 42 16 8.6
[72]
HepG2 NR2F6
Mean 36.7
Standard deviation 6.8
Values 32 42
[73]
HepG2.C3A NR2F6
Mean 27.8
Standard deviation 0.054
Values 28 28
[74]
HuH.7 NR2F6
Mean 51.5
Standard deviation 9.9
Values 62 51 42
[75]
SNU475 NR2F6
Mean 15.8
Standard deviation 2.3
Values 14 17
[76]
THLE NR2F6
Mean 14.8
Standard deviation 2.5
Values 13 17
[77]
liver NR2F6
Mean 28.6
Standard deviation 11
Values 41 26 34 14
[78]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 10 7.4 7.5 33 53
[79]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 76 58
[80]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 92 68
[81]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 61 77 86
[82]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 76 75
[83]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[84]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 80 99 60 62
[85]
ref_hepatocyte HDAC1
Mean 20.8
Standard deviation 4.1
Values 19 18 18 22 28
[86]
HepG2 HDAC1
Mean 65.4
Standard deviation 11
Values 58 73
[87]
HepG2.C3A HDAC1
Mean 58.9
Standard deviation 2.3
Values 60 57
[88]
HuH.7 HDAC1
Mean 90.9
Standard deviation 22
Values 1.1e+02 68 94
[89]
SNU475 HDAC1
Mean 59.8
Standard deviation 8
Values 54 65
[90]
THLE HDAC1
Mean 57.8
Standard deviation 6.8
Values 53 63
[91]
liver HDAC1
Mean 21.5
Standard deviation 6.8
Values 14 18 25 29
[92]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 20 17 14 27 26
[93]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1.1e+02 1e+02
[94]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[95]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 93 78 89
[96]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 57 55
[97]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[98]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 22 50 50
[99]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 19 18 12 17 35
[100]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 49 36
[101]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 25 15
[102]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 40 38 47
[103]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 1.1e+02 3.2e+02
[104]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[105]
liver STAT1
Mean 55.8
Standard deviation 15
Values 38 69 49 67
[106]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 6.7 27 28 5.4 16
[107]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 12 11
[108]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 12 10
[109]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5.5 6.4 5
[110]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 13 16
[111]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[112]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 3.7 3.7 16 12
[113]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 19 16 26 5.8 17
[114]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[115]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 93 77
[116]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 85 84 89
[117]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 1.7e+02 2.2e+02
[118]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[119]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 37 56
[120]
ref_hepatocyte IL6ST
Mean 16.5
Standard deviation 5.8
Values 9.5 19 12 24 18
[121]
HepG2 IL6ST
Mean 43.6
Standard deviation 25
Values 61 26
[122]
HepG2.C3A IL6ST
Mean 92.3
Standard deviation 8.3
Values 98 86
[123]
HuH.7 IL6ST
Mean 63.5
Standard deviation 38
Values 35 1.1e+02 50
[124]
SNU475 IL6ST
Mean 100
Standard deviation 15
Values 1.1e+02 90
[125]
THLE IL6ST
Mean 252
Standard deviation 68
Values 3e+02 2e+02
[126]
liver IL6ST
Mean 321
Standard deviation 1.1e+02
Values 4.1e+02 4.2e+02 2.5e+02 2.1e+02
[127]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 18 10 14 6.8 27
[128]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 56 40
[129]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 29 31
[130]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 29 32 36
[131]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 39 47
[132]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[133]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 62 75 54 58
[134]
ref_hepatocyte SOCS3
Mean 11.2
Standard deviation 10
Values 19 10 24 1 1.5
[135]
HepG2 SOCS3
Mean 1.4
Standard deviation 0.4
Values 1.1 1.7
[136]
HepG2.C3A SOCS3
Mean 0.939
Standard deviation 0.87
Values 0.32 1.6
[137]
HuH.7 SOCS3
Mean 2.97
Standard deviation 2.7
Values 1.4 6.1 1.4
[138]
SNU475 SOCS3
Mean 11.8
Standard deviation 0.67
Values 11 12
[139]
THLE SOCS3
Mean 6.29
Standard deviation 1.1
Values 7.1 5.5
[140]
liver SOCS3
Mean 17.4
Standard deviation 5.5
Values 26 14 15 15
[141]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[142]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[143]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[144]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[145]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[146]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[147]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[148]
ref_hepatocyte IL6R
Mean 10.5
Standard deviation 4.3
Values 17 11 6.6 6.9 11
[149]
HepG2 IL6R
Mean 20
Standard deviation 0.31
Values 20 20
[150]
HepG2.C3A IL6R
Mean 22.3
Standard deviation 0.4
Values 23 22
[151]
HuH.7 IL6R
Mean 12.1
Standard deviation 3.9
Values 9.4 17 10
[152]
SNU475 IL6R
Mean 10.6
Standard deviation 4
Values 7.7 13
[153]
THLE IL6R
Mean 0.69
Standard deviation 0.095
Values 0.76 0.62
[154]
liver IL6R
Mean 47.1
Standard deviation 10
Values 57 49 49 33
[155]
ref_hepatocyte MAP3K7
Mean 8.64
Standard deviation 6.6
Values 4.6 3.6 4 18 13
[156]
HepG2 MAP3K7
Mean 17.8
Standard deviation 6.7
Values 23 13
[157]
HepG2.C3A MAP3K7
Mean 33.3
Standard deviation 3
Values 35 31
[158]
HuH.7 MAP3K7
Mean 29.2
Standard deviation 2.3
Values 30 27 31
[159]
SNU475 MAP3K7
Mean 22.3
Standard deviation 2.2
Values 21 24
[160]
THLE MAP3K7
Mean 28.3
Standard deviation 1.5
Values 29 27
[161]
liver MAP3K7
Mean 14.6
Standard deviation 1.8
Values 12 16 14 16
[162]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.2 14 8.1 4.1 7.4
[163]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 14 9.8
[164]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 13 9.6
[165]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 15 32 23
[166]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 35 80
[167]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[168]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1.4e+02 1e+02 64 32
[169]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 2.2 1.5 1.3 27 1.9
[170]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 19 9.4
[171]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 33 39
[172]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 15 37 22
[173]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 20 25
[174]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[175]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 16 18 13 9.3
[176]
ref_hepatocyte IRF1
Mean 6.09
Standard deviation 3.2
Values 11 4.2 7.1 3.2 4.7
[177]
HepG2 IRF1
Mean 9.46
Standard deviation 1.7
Values 11 8.2
[178]
HepG2.C3A IRF1
Mean 6.08
Standard deviation 0.89
Values 5.4 6.7
[179]
HuH.7 IRF1
Mean 6.43
Standard deviation 1.6
Values 6.1 8.1 5.1
[180]
SNU475 IRF1
Mean 26.8
Standard deviation 8.1
Values 21 32
[181]
THLE IRF1
Mean 15
Standard deviation 0.58
Values 15 15
[182]
liver IRF1
Mean 15.4
Standard deviation 7.2
Values 13 6.7 23 19
[183]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 3.1 3.8 4.9 11 3.2
[184]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 41 44
[185]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 35 53
[186]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 64 55 75
[187]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 13 18
[188]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[189]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6.9 6 7.6 3.8
[190]
ref_hepatocyte MAP2K4
Mean 5.23
Standard deviation 0.4
Values 5.1 5.2 4.9 5.1 5.9
[191]
HepG2 MAP2K4
Mean 18.8
Standard deviation 5.8
Values 23 15
[192]
HepG2.C3A MAP2K4
Mean 26
Standard deviation 3.4
Values 28 24
[193]
HuH.7 MAP2K4
Mean 14.3
Standard deviation 2.4
Values 12 17 14
[194]
SNU475 MAP2K4
Mean 22.2
Standard deviation 0.79
Values 22 23
[195]
THLE MAP2K4
Mean 16.4
Standard deviation 1.6
Values 15 17
[196]
liver MAP2K4
Mean 15.6
Standard deviation 2
Values 13 17 16 17
[197]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 5.2 5.6 6.8 2.6 4
[198]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 24 23
[199]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 25 29
[200]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 31 19 35
[201]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[202]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[203]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 30 24 31 24
[204]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[205]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[206]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[207]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[208]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[209]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[210]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[211]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[212]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[213]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[214]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[215]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[216]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[217]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[218]
ref_hepatocyte PRKCD
Mean 3.58
Standard deviation 2
Values 5.5 1.5 2.1 5.9 2.9
[219]
HepG2 PRKCD
Mean 16.9
Standard deviation 3.4
Values 15 19
[220]
HepG2.C3A PRKCD
Mean 17.9
Standard deviation 3.3
Values 16 20
[221]
HuH.7 PRKCD
Mean 12
Standard deviation 0.2
Values 12 12 12
[222]
SNU475 PRKCD
Mean 4.64
Standard deviation 0.32
Values 4.9 4.4
[223]
THLE PRKCD
Mean 11.6
Standard deviation 1.2
Values 11 12
[224]
liver PRKCD
Mean 2.43
Standard deviation 1
Values 2.3 1.4 3.9 2.2
[225]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 1.9 2.1 2 5.1 4.9
[226]
HepG2 RPS6KB1
Missing
[227]
HepG2.C3A RPS6KB1
Missing
[228]
HuH.7 RPS6KB1
Missing
[229]
SNU475 RPS6KB1
Missing
[230]
THLE RPS6KB1
Missing
[231]
liver RPS6KB1
Missing
[232]
ref_hepatocyte NLK
Mean 2.34
Standard deviation 0.7
Values 3.6 2.3 2 1.8 2.1
[233]
HepG2 NLK
Mean 6.24
Standard deviation 0.69
Values 6.7 5.7
[234]
HepG2.C3A NLK
Mean 8.21
Standard deviation 1.4
Values 7.2 9.2
[235]
HuH.7 NLK
Mean 11.1
Standard deviation 0.74
Values 10 12 11
[236]
SNU475 NLK
Mean 7.05
Standard deviation 0.25
Values 7.2 6.9
[237]
THLE NLK
Mean 6.67
Standard deviation 0.093
Values 6.6 6.7
[238]
liver NLK
Mean 5.82
Standard deviation 1.3
Values 6 7.3 5.8 4.1
[239]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.1 2.8 2.8 1.8 2
[240]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 7.4 5.4
[241]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 9 7.9
[242]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 6.6 12 9.2
[243]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 13 14
[244]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[245]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 22 23 17 13
[246]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 2.6 1.9 1.9 1.8 0.72
[247]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 31 27
[248]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 14 16
[249]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 14 24 28
[250]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[251]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[252]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 28 21 30 17
[253]
ref_hepatocyte HCK
Mean 1.57
Standard deviation 1.7
Values 2.7 3.9 1.2 0 0
[254]
HepG2 HCK
Mean 0.0602
Standard deviation 0.085
Values 0 0.12
[255]
HepG2.C3A HCK
Mean 0.0473
Standard deviation 0.039
Values 0.075 0.019
[256]
HuH.7 HCK
Mean 0
Standard deviation 0
Values 0 0 0
[257]
SNU475 HCK
Mean 0.0747
Standard deviation 0.066
Values 0.12 0.028
[258]
THLE HCK
Mean 0.0438
Standard deviation 0.047
Values 0.077 0.011
[259]
liver HCK
Mean 3.63
Standard deviation 1.3
Values 4.7 4.2 1.7 4
[260]
ref_hepatocyte IL6
Mean 1.35
Standard deviation 2.5
Values 5.9 0.28 0.6 0 0
[261]
HepG2 IL6
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[262]
HepG2.C3A IL6
Mean 0
Standard deviation 0
Values 0 0
[263]
HuH.7 IL6
Mean 0.0895
Standard deviation 0.012
Values 0.1 0.083 0.082
[264]
SNU475 IL6
Mean 1.37
Standard deviation 1.7
Values 2.6 0.15
[265]
THLE IL6
Mean 8.81
Standard deviation 1.5
Values 7.7 9.9
[266]
liver IL6
Mean 0
Standard deviation 0
Values 0 0 0 0
[267]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 0.33 0.66 0.38 2 0.61
[268]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 5.8 2.8
[269]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 9.8 6.5
[270]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 7.3 8.1 10
[271]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 4.4 6.6
[272]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[273]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 10 10 7.1 5.3
[274]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 0.62 0.5 0.18 1.3 1.3
[275]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 2.9 1
[276]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 2.2 1.3
[277]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 0.9 1.6 1.2
[278]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.4 2.3
[279]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[280]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 9.8 11 4.7 2.9
[281]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0.63 1 0.48 0 0.2
[282]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[283]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.097 0.049
[284]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.028 0.019 0.016
[285]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0.025 0
[286]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[287]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 2.6 1.8 0.75 0.82
[288]
ref_hepatocyte PRDM1
Mean 0.123
Standard deviation 0.21
Values 0 0.5 0.12 0 0
[289]
HepG2 PRDM1
Mean 0.0193
Standard deviation 0.021
Values 0.0043 0.034
[290]
HepG2.C3A PRDM1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[291]
HuH.7 PRDM1
Mean 0.63
Standard deviation 0.2
Values 0.49 0.85 0.55
[292]
SNU475 PRDM1
Mean 2.32
Standard deviation 0.44
Values 2.6 2
[293]
THLE PRDM1
Mean 0.522
Standard deviation 0.015
Values 0.53 0.51
[294]
liver PRDM1
Mean 1.81
Standard deviation 1.3
Values 0.9 0.87 3.6 1.9
[295]
ref_hepatocyte VIP
Mean 0.0407
Standard deviation 0.091
Values 0 0.2 0 0 0
[296]
HepG2 VIP
Mean 0.0451
Standard deviation 0.058
Values 0.0043 0.086
[297]
HepG2.C3A VIP
Mean 0.0414
Standard deviation 0.017
Values 0.054 0.029
[298]
HuH.7 VIP
Mean 0
Standard deviation 0
Values 0 0 0
[299]
SNU475 VIP
Mean 0.0933
Standard deviation 0.04
Values 0.12 0.065
[300]
THLE VIP
Mean 0.0254
Standard deviation 0.0059
Values 0.03 0.021
[301]
liver VIP
Mean 0.183
Standard deviation 0.24
Values 0.079 0.086 0.54 0.026