WP_IL1_AND_MEGAKARYOCYTES_IN_OBESITY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 F2 Prothrombin [1] -0.98[2] -0.19[3] 0.05[4] -8.78[5] -10.14[6] 0.17[7]
2 TIMP1 Metalloproteinase inhibitor 1 [8] -0.95[9] -2.28[10] -9.60[11] -0.19[12] 0.38[13] -0.20[14]
3 SELENBP1 Selenium-binding protein 1 [15] -2.57[16] -1.73[17] -2.17[18] 0.41[19] -1.63[20] -0.19[21]
4 S100A9 Protein S100-A9 [22] -4.90[23] -7.08[24] -5.26[25] -6.95[26] -8.48[27] -2.10[28]
5 IRAK1 Interleukin-1 receptor-associated kinase 1 [29] 2.69[30] 2.38[31] 1.22[32] 2.57[33] 1.93[34] -0.84[35]
6 IL1R1 Interleukin-1 receptor type 1 [36] 0.70[37] 0.64[38] -0.15[39] 0.95[40] 2.61[41] 0.62[42]
7 IL18 Interleukin-18 [43] 0.41[44] -3.13[45] 0.86[46] 0.60[47] -1.07[48] -4.31[49]
8 ICAM1 Intercellular adhesion molecule 1 [50] 3.17[51] 2.84[52] 3.11[53] 1.96[54] 3.13[55] -0.56[56]
9 MYD88 Myeloid differentiation primary response protein MyD88 [57] 1.09[58] 1.44[59] 0.73[60] 0.73[61] 0.03[62] 0.64[63]
10 CCL2 C-C motif chemokine 2 [64] -12.12[65] [66] -11.39[67] -2.35[68] -1.19[69] -3.84[70]
11 TIMP2 Metalloproteinase inhibitor 2 [71] 3.50[72] 1.44[73] -0.51[74] 4.86[75] 4.56[76] -0.30[77]
12 NFKB1 Nuclear factor NF-kappa-B p105 subunit [78] 1.94[79] 1.92[80] 1.56[81] 1.52[82] 1.43[83] 0.30[84]
13 IL1B Interleukin-1 beta [85] -7.42[86] -7.00[87] -2.81[88] -1.82[89] 2.76[90] -5.35[91]
14 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.89[92] 2.83[93] 2.87[94] 2.90[95] 2.10[96] 1.76[97]
15 HBEGF Proheparin-binding EGF-like growth factor [98] 0.29[99] -0.23[100] -1.44[101] 2.07[102] 0.76[103] -2.58[104]
16 TLR2 Toll-like receptor 2 [105] -2.27[106] -0.56[107] -7.70[108] -3.20[109] 2.55[110] 1.09[111]
17 F2R Proteinase-activated receptor 1 [112] 4.12[113] 2.89[114] 3.31[115] 5.61[116] 4.02[117] 2.58[118]
18 PLA2G7 Platelet-activating factor acetylhydrolase [119] -4.87[120] -2.80[121] 4.55[122] -3.00[123] -3.73[124] -0.21[125]
19 MMP9 Matrix metalloproteinase-9 [126] -1.44[127] -2.20[128] -4.74[129] 0.34[130] -3.23[131] -0.29[132]
20 TLR1 Toll-like receptor 1 [133] -2.09[134] [135] -5.59[136] 1.38[137] 1.55[138] 1.91[139]
21 IFNG Interferon gamma [140] [141] [142] [143] 1.08[144] [145] -2.45[146]
22 FCER1A High affinity immunoglobulin epsilon receptor subunit alpha [147] [148] [149] [150] [151] -3.16[152] -2.01[153]
23 NLRP3 NACHT, LRR and PYD domains-containing protein 3 [154] -2.36[155] 0.17[156] -1.77[157] 0.38[158] 1.86[159] 1.44[160]
24 CCR3 C-C chemokine receptor type 3 [161] [162] [163] [164] [165] [166] [167]
25 MIR718 [168] [169] [170] [171] [172] [173] [174]
[1]
ref_hepatocyte F2
Mean 442
Standard deviation 5.2e+02
Values 98 1.2e+03 8.2e+02 40 79
[2]
HepG2 F2
Mean 204
Standard deviation 81
Values 1.5e+02 2.6e+02
[3]
HepG2.C3A F2
Mean 256
Standard deviation 95
Values 1.9e+02 3.2e+02
[4]
HuH.7 F2
Mean 321
Standard deviation 18
Values 3.4e+02 3.1e+02 3.1e+02
[5]
SNU475 F2
Mean 0.54
Standard deviation 0.16
Values 0.43 0.65
[6]
THLE F2
Mean 0.475
Standard deviation 0.27
Values 0.66 0.29
[7]
liver F2
Mean 785
Standard deviation 2.9e+02
Values 5.3e+02 5.3e+02 1e+03 1e+03
[8]
ref_hepatocyte TIMP1
Mean 124
Standard deviation 1.5e+02
Values 2e+02 61 3.5e+02 1 7.3
[9]
HepG2 TIMP1
Mean 58.4
Standard deviation 10
Values 66 51
[10]
HepG2.C3A TIMP1
Mean 16.9
Standard deviation 5.3
Values 21 13
[11]
HuH.7 TIMP1
Mean 0.112
Standard deviation 0.04
Values 0.075 0.15 0.11
[12]
SNU475 TIMP1
Mean 58.3
Standard deviation 15
Values 69 48
[13]
THLE TIMP1
Mean 195
Standard deviation 24
Values 2.1e+02 1.8e+02
[14]
liver TIMP1
Mean 170
Standard deviation 2.5e+02
Values 9.9 7.4 5.3e+02 1.3e+02
[15]
ref_hepatocyte SELENBP1
Mean 56.9
Standard deviation 76
Values 3.8 1.7e+02 1.1e+02 3.5 1.5
[16]
HepG2 SELENBP1
Mean 8.73
Standard deviation 0.6
Values 9.2 8.3
[17]
HepG2.C3A SELENBP1
Mean 11.4
Standard deviation 1.7
Values 13 10
[18]
HuH.7 SELENBP1
Mean 8.91
Standard deviation 2.6
Values 10 5.9 10
[19]
SNU475 SELENBP1
Mean 40.8
Standard deviation 19
Values 27 54
[20]
THLE SELENBP1
Mean 22.3
Standard deviation 0.82
Values 22 23
[21]
liver SELENBP1
Mean 78.7
Standard deviation 53
Values 45 42 1.5e+02 73
[22]
ref_hepatocyte S100A9
Mean 27.8
Standard deviation 27
Values 61 32 46 0 0.21
[23]
HepG2 S100A9
Mean 0.849
Standard deviation 0.92
Values 0.2 1.5
[24]
HepG2.C3A S100A9
Mean 0.136
Standard deviation 0.11
Values 0.21 0.058
[25]
HuH.7 S100A9
Mean 0.51
Standard deviation 0.36
Values 0.84 0.12 0.57
[26]
SNU475 S100A9
Mean 0.121
Standard deviation 0.15
Values 0.23 0.014
[27]
THLE S100A9
Mean 0.0943
Standard deviation 0.051
Values 0.13 0.059
[28]
liver S100A9
Mean 10.3
Standard deviation 5.8
Values 11 4.3 7.9 18
[29]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 38 5 16 18 30
[30]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 97 1.5e+02
[31]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 75 72
[32]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 34 31 40
[33]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 78 58
[34]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[35]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 24 19 17 15
[36]
ref_hepatocyte IL1R1
Mean 16.2
Standard deviation 7
Values 12 18 17 26 7.8
[37]
HepG2 IL1R1
Mean 24.1
Standard deviation 14
Values 34 14
[38]
HepG2.C3A IL1R1
Mean 16.7
Standard deviation 3.1
Values 19 14
[39]
HuH.7 IL1R1
Mean 10.2
Standard deviation 4
Values 7.6 15 8.3
[40]
SNU475 IL1R1
Mean 16.8
Standard deviation 1.1
Values 18 16
[41]
THLE IL1R1
Mean 120
Standard deviation 0.57
Values 1.2e+02 1.2e+02
[42]
liver IL1R1
Mean 39.3
Standard deviation 8.9
Values 42 47 27 41
[43]
ref_hepatocyte IL18
Mean 13.1
Standard deviation 19
Values 18 2 0.77 0 45
[44]
HepG2 IL18
Mean 15.9
Standard deviation 5.6
Values 12 20
[45]
HepG2.C3A IL18
Mean 0.993
Standard deviation 0.7
Values 1.5 0.5
[46]
HuH.7 IL18
Mean 16.7
Standard deviation 4.3
Values 16 21 13
[47]
SNU475 IL18
Mean 10.7
Standard deviation 5.7
Values 15 6.7
[48]
THLE IL18
Mean 7.57
Standard deviation 2
Values 6.2 9
[49]
liver IL18
Mean 1.04
Standard deviation 0.48
Values 0.7 0.56 1.4 1.5
[50]
ref_hepatocyte ICAM1
Mean 13.1
Standard deviation 10
Values 30 4.6 13 4.8 13
[51]
HepG2 ICAM1
Mean 108
Standard deviation 42
Values 78 1.4e+02
[52]
HepG2.C3A ICAM1
Mean 62
Standard deviation 30
Values 41 83
[53]
HuH.7 ICAM1
Mean 79.4
Standard deviation 15
Values 67 96 76
[54]
SNU475 ICAM1
Mean 27.3
Standard deviation 7.9
Values 33 22
[55]
THLE ICAM1
Mean 139
Standard deviation 24
Values 1.2e+02 1.6e+02
[56]
liver ICAM1
Mean 13.9
Standard deviation 5
Values 13 9.4 12 21
[57]
ref_hepatocyte MYD88
Mean 12.3
Standard deviation 6.2
Values 14 17 19 5.4 6
[58]
HepG2 MYD88
Mean 23.8
Standard deviation 12
Values 32 16
[59]
HepG2.C3A MYD88
Mean 22.1
Standard deviation 5.1
Values 26 18
[60]
HuH.7 MYD88
Mean 14.3
Standard deviation 1.1
Values 15 13 15
[61]
SNU475 MYD88
Mean 11
Standard deviation 1.1
Values 10 12
[62]
THLE MYD88
Mean 15.1
Standard deviation 1.7
Values 14 16
[63]
liver MYD88
Mean 30.3
Standard deviation 21
Values 14 9.8 47 51
[64]
ref_hepatocyte CCL2
Mean 10.5
Standard deviation 21
Values 47 0.22 2.1 0 2.9
[65]
HepG2 CCL2
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[66]
HepG2.C3A CCL2
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 CCL2
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[68]
SNU475 CCL2
Mean 1.11
Standard deviation 0.87
Values 1.7 0.49
[69]
THLE CCL2
Mean 5.56
Standard deviation 0.79
Values 5 6.1
[70]
liver CCL2
Mean 1.15
Standard deviation 1.1
Values 0.4 0.19 2.6 1.4
[71]
ref_hepatocyte TIMP2
Mean 7.86
Standard deviation 14
Values 1.4 1.6 1.6 34 1
[72]
HepG2 TIMP2
Mean 80.9
Standard deviation 4.5
Values 78 84
[73]
HepG2.C3A TIMP2
Mean 14.2
Standard deviation 2
Values 13 16
[74]
HuH.7 TIMP2
Mean 3.88
Standard deviation 2.3
Values 2 6.5 3.2
[75]
SNU475 TIMP2
Mean 123
Standard deviation 31
Values 1e+02 1.4e+02
[76]
THLE TIMP2
Mean 225
Standard deviation 43
Values 1.9e+02 2.6e+02
[77]
liver TIMP2
Mean 10.1
Standard deviation 3.4
Values 7.3 7.7 15 11
[78]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[79]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[80]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[81]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[82]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[83]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[84]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[85]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[86]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[87]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[88]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[89]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[90]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[91]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[92]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 0.94 1.2 2.3 2.6
[93]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 4.3 2.1
[94]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 9.6 8
[95]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 7 12 10
[96]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 6.8 8.1
[97]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[98]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 13 15 6.1 6
[99]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 3.8 0.34 0.78 1 3.1
[100]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 1.9 2.1
[101]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 0.82 1.2
[102]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.46 0.43 0.52
[103]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 4.4 3.9
[104]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[105]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.46 0.27 0.89 0.28
[106]
ref_hepatocyte TLR2
Mean 1.56
Standard deviation 1.2
Values 2.3 1.4 3.1 0 0.96
[107]
HepG2 TLR2
Mean 0.296
Standard deviation 0.084
Values 0.24 0.36
[108]
HepG2.C3A TLR2
Mean 0.704
Standard deviation 0.0056
Values 0.71 0.7
[109]
HuH.7 TLR2
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[110]
SNU475 TLR2
Mean 0.0914
Standard deviation 0.057
Values 0.13 0.051
[111]
THLE TLR2
Mean 11.1
Standard deviation 4.3
Values 14 8.1
[112]
liver TLR2
Mean 5.26
Standard deviation 1.6
Values 5.9 6.8 3.2 5.1
[113]
ref_hepatocyte F2R
Mean 1.14
Standard deviation 1.1
Values 0.66 0.46 0.48 3 1.1
[114]
HepG2 F2R
Mean 18.1
Standard deviation 2.7
Values 16 20
[115]
HepG2.C3A F2R
Mean 5.61
Standard deviation 1.6
Values 6.7 4.5
[116]
HuH.7 F2R
Mean 7.91
Standard deviation 2.3
Values 7.7 5.7 10
[117]
SNU475 F2R
Mean 30
Standard deviation 14
Values 20 40
[118]
THLE F2R
Mean 22.4
Standard deviation 11
Values 15 30
[119]
liver F2R
Mean 10.8
Standard deviation 2.8
Values 7.7 10 11 14
[120]
ref_hepatocyte PLA2G7
Mean 0.869
Standard deviation 0.49
Values 1.1 0.71 0.41 1.6 0.54
[121]
HepG2 PLA2G7
Mean 0.0272
Standard deviation 0.0021
Values 0.026 0.029
[122]
HepG2.C3A PLA2G7
Mean 0.0828
Standard deviation 0.035
Values 0.11 0.058
[123]
HuH.7 PLA2G7
Mean 14.3
Standard deviation 2
Values 14 12 16
[124]
SNU475 PLA2G7
Mean 0.0585
Standard deviation 0.011
Values 0.066 0.051
[125]
THLE PLA2G7
Mean 0.0792
Standard deviation 0.022
Values 0.095 0.064
[126]
liver PLA2G7
Mean 1.18
Standard deviation 0.76
Values 0.89 2.1 0.31 1.5
[127]
ref_hepatocyte MMP9
Mean 0.779
Standard deviation 1.6
Values 3.7 0.033 0.06 0.1 0.049
[128]
HepG2 MMP9
Mean 0.261
Standard deviation 0.18
Values 0.13 0.39
[129]
HepG2.C3A MMP9
Mean 0.112
Standard deviation 0.0078
Values 0.12 0.11
[130]
HuH.7 MMP9
Mean 0.0205
Standard deviation 0.012
Values 0.0094 0.019 0.033
[131]
SNU475 MMP9
Mean 0.53
Standard deviation 0.7
Values 1 0.037
[132]
THLE MMP9
Mean 0.101
Standard deviation 0.076
Values 0.047 0.15
[133]
liver MMP9
Mean 1
Standard deviation 0.93
Values 2.4 0.73 0.33 0.59
[134]
ref_hepatocyte TLR1
Mean 0.481
Standard deviation 0.24
Values 0.38 0.7 0.69 0.12 0.52
[135]
HepG2 TLR1
Mean 0.103
Standard deviation 0.024
Values 0.086 0.12
[136]
HepG2.C3A TLR1
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 TLR1
Mean 0.00701
Standard deviation 0.0065
Values 0 0.013 0.0082
[138]
SNU475 TLR1
Mean 0.672
Standard deviation 0.026
Values 0.65 0.69
[139]
THLE TLR1
Mean 1.71
Standard deviation 0.1
Values 1.8 1.6
[140]
liver TLR1
Mean 2.86
Standard deviation 1.1
Values 3 4.4 2 2.1
[141]
ref_hepatocyte IFNG
Mean 0.182
Standard deviation 0.29
Values 0 0.67 0.23 0 0
[142]
HepG2 IFNG
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A IFNG
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 IFNG
Mean 0
Standard deviation 0
Values 0 0 0
[145]
SNU475 IFNG
Mean 0.206
Standard deviation 0.22
Values 0.051 0.36
[146]
THLE IFNG
Mean 0
Standard deviation 0
Values 0 0
[147]
liver IFNG
Mean 0.0524
Standard deviation 0.037
Values 0.026 0.057 0.024 0.1
[148]
ref_hepatocyte FCER1A
Mean 0.146
Standard deviation 0.22
Values 0 0.49 0.24 0 0
[149]
HepG2 FCER1A
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A FCER1A
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 FCER1A
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 FCER1A
Mean 0
Standard deviation 0
Values 0 0
[153]
THLE FCER1A
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[154]
liver FCER1A
Mean 0.0572
Standard deviation 0.057
Values 0 0.13 0.024 0.077
[155]
ref_hepatocyte NLRP3
Mean 0.117
Standard deviation 0.12
Values 0 0.19 0.28 0 0.11
[156]
HepG2 NLRP3
Mean 0.0207
Standard deviation 0.013
Values 0.03 0.011
[157]
HepG2.C3A NLRP3
Mean 0.0871
Standard deviation 0.013
Values 0.097 0.078
[158]
HuH.7 NLRP3
Mean 0.024
Standard deviation 0.036
Values 0.066 0.0064 0
[159]
SNU475 NLRP3
Mean 0.0819
Standard deviation 0.063
Values 0.13 0.037
[160]
THLE NLRP3
Mean 0.513
Standard deviation 0.15
Values 0.62 0.4
[161]
liver NLRP3
Mean 0.499
Standard deviation 0.28
Values 0.58 0.84 0.19 0.39
[162]
ref_hepatocyte CCR3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 CCR3
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A CCR3
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 CCR3
Mean 0.0758
Standard deviation 0.032
Values 0.1 0.083 0.041
[166]
SNU475 CCR3
Mean 0.0266
Standard deviation 0.0018
Values 0.025 0.028
[167]
THLE CCR3
Mean 0
Standard deviation 0
Values 0 0
[168]
liver CCR3
Mean 0.0212
Standard deviation 0.034
Values 0 0.014 0.071 0
[169]
ref_hepatocyte MIR718
Missing
[170]
HepG2 MIR718
Missing
[171]
HepG2.C3A MIR718
Missing
[172]
HuH.7 MIR718
Missing
[173]
SNU475 MIR718
Missing
[174]
THLE MIR718
Missing
[175]
liver MIR718
Missing