WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | IFITM3 | Interferon-induced transmembrane protein 3 | [1] | -3.18[2] | -4.14[3] | -4.22[4] | -1.97[5] | -3.87[6] | -0.55[7] |
2 | IFITM2 | Interferon-induced transmembrane protein 2 | [8] | -3.02[9] | -2.70[10] | -6.64[11] | -3.11[12] | -3.69[13] | -0.01[14] |
3 | BST2 | Bone marrow stromal antigen 2 | [15] | -0.12[16] | -0.56[17] | -7.02[18] | -1.84[19] | -0.47[20] | -0.39[21] |
4 | JUN | Transcription factor AP-1 | [22] | 1.48[23] | -0.12[24] | 0.29[25] | 0.56[26] | 1.12[27] | -0.62[28] |
5 | FOS | Proto-oncogene c-Fos | [29] | -4.04[30] | -2.83[31] | -3.36[32] | -3.90[33] | -2.85[34] | -0.12[35] |
6 | JUNB | Transcription factor jun-B | [36] | 0.02[37] | -0.90[38] | -0.05[39] | 0.10[40] | 0.93[41] | -0.20[42] |
7 | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 | [43] | 0.75[44] | 1.00[45] | 0.03[46] | 0.44[47] | 0.29[48] | -0.25[49] |
8 | IFITM1 | Interferon-induced transmembrane protein 1 | [50] | -3.61[51] | -1.46[52] | -6.21[53] | -3.11[54] | -1.97[55] | 0.12[56] |
9 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [57] | 1.04[58] | 0.66[59] | 1.38[60] | 1.72[61] | 2.22[62] | 0.00[63] |
10 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [64] | 2.03[65] | 1.65[66] | 2.66[67] | 1.42[68] | 1.90[69] | -0.51[70] |
11 | DDIT3 | DNA damage-inducible transcript 3 protein | [71] | -0.01[72] | 0.71[73] | 0.67[74] | 0.16[75] | 1.03[76] | -1.00[77] |
12 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [78] | 1.91[79] | 2.26[80] | 3.67[81] | 2.08[82] | 2.93[83] | 2.28[84] |
13 | EIF4E | Eukaryotic translation initiation factor 4E | [85] | 2.11[86] | 2.88[87] | 2.39[88] | 1.99[89] | 3.01[90] | 1.36[91] |
14 | MAP3K11 | Mitogen-activated protein kinase kinase kinase 11 | [92] | 3.06[93] | 2.95[94] | 2.71[95] | 2.41[96] | 2.26[97] | 1.65[98] |
15 | MAPK1 | Mitogen-activated protein kinase 1 | [99] | 3.68[100] | 3.76[101] | 3.73[102] | 4.12[103] | 3.75[104] | 2.96[105] |
16 | RPS6KA3 | Ribosomal protein S6 kinase alpha-3 | [106] | [107] | [108] | [109] | [110] | [111] | [112] |
17 | MAPK14 | Mitogen-activated protein kinase 14 | [113] | 3.45[114] | 3.46[115] | 3.18[116] | 3.95[117] | 3.41[118] | 2.47[119] |
18 | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 | [120] | 2.61[121] | 3.60[122] | 3.97[123] | 3.05[124] | 2.81[125] | 2.21[126] |
19 | MAPK8 | Mitogen-activated protein kinase 8 | [127] | 0.53[128] | 1.88[129] | 0.89[130] | 1.36[131] | 1.21[132] | 0.68[133] |
20 | IFI27 | Interferon alpha-inducible protein 27, mitochondrial | [134] | 0.30[135] | -2.94[136] | -4.46[137] | 1.36[138] | -4.29[139] | 1.59[140] |
21 | MAPK13 | Mitogen-activated protein kinase 13 | [141] | 4.31[142] | 4.66[143] | 2.12[144] | 0.38[145] | 1.89[146] | -0.53[147] |
22 | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 | [148] | 2.68[149] | 3.25[150] | 2.59[151] | 3.47[152] | 2.86[153] | 2.25[154] |
23 | RPS6KA1 | Ribosomal protein S6 kinase alpha-1 | [155] | [156] | [157] | [158] | [159] | [160] | [161] |
24 | MAPK9 | Mitogen-activated protein kinase 9 | [162] | 3.20[163] | 3.37[164] | 3.57[165] | 3.98[166] | 3.42[167] | 1.70[168] |
25 | MAPK3 | Mitogen-activated protein kinase 3 | [169] | 3.82[170] | 3.81[171] | 3.99[172] | 2.69[173] | 2.70[174] | 0.15[175] |
26 | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 | [176] | 2.93[177] | 3.03[178] | 3.74[179] | 2.55[180] | 3.09[181] | 0.43[182] |
27 | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 | [183] | 2.92[184] | 3.54[185] | 2.82[186] | 3.13[187] | 3.40[188] | 2.58[189] |
28 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [190] | 2.26[191] | -1.01[192] | 3.99[193] | 3.28[194] | -0.77[195] | -0.43[196] |
29 | RPS6KA2 | Ribosomal protein S6 kinase alpha-2 | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | MAP3K10 | Mitogen-activated protein kinase kinase kinase 10 | [204] | 2.97[205] | 2.33[206] | 2.75[207] | 2.44[208] | 3.27[209] | 0.40[210] |
31 | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 | [211] | 4.62[212] | 4.28[213] | 4.15[214] | 4.59[215] | 3.46[216] | 3.99[217] |
32 | MAPK12 | Mitogen-activated protein kinase 12 | [218] | 4.79[219] | 4.40[220] | 5.65[221] | 3.75[222] | 4.99[223] | 0.28[224] |
33 | MAP3K9 | Mitogen-activated protein kinase kinase kinase 9 | [225] | 4.19[226] | 3.66[227] | 3.62[228] | 4.85[229] | 3.05[230] | 2.87[231] |
34 | MAPK11 | Mitogen-activated protein kinase 11 | [232] | 1.80[233] | 1.64[234] | 0.89[235] | 2.62[236] | 4.60[237] | 1.35[238] |
35 | BCL2 | Apoptosis regulator Bcl-2 | [239] | -0.88[240] | 4.47[241] | -2.80[242] | 4.04[243] | 3.74[244] | 4.42[245] |
36 | MAPK10 | Mitogen-activated protein kinase 10 | [246] | 0.49[247] | [248] | [249] | 11.17[250] | 6.90[251] | 8.43[252] |