WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_INTERFERON_INDUC | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | NFKBIA | NF-kappa-B inhibitor alpha | [1] | -0.90[2] | -2.46[3] | -2.65[4] | -3.59[5] | -1.43[6] | -1.49[7] |
2 | JUN | Transcription factor AP-1 | [8] | -0.34[9] | -1.64[10] | -1.19[11] | -1.77[12] | -0.93[13] | -2.16[14] |
3 | FOS | Proto-oncogene c-Fos | [15] | -5.86[16] | -4.36[17] | -4.84[18] | -6.24[19] | -4.90[20] | -1.66[21] |
4 | IKBKG | NF-kappa-B essential modulator | [22] | -0.73[23] | -0.35[24] | -2.41[25] | -0.92[26] | -1.86[27] | -0.96[28] |
5 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [29] | 0.08[30] | -0.60[31] | 0.69[32] | 2.46[33] | 0.47[34] | 0.60[35] |
6 | JAK1 | Tyrosine-protein kinase JAK1 | [36] | 0.67[37] | 0.39[38] | 0.76[39] | 0.56[40] | 1.47[41] | 1.18[42] |
7 | IRF9 | Interferon regulatory factor 9 | [43] | -0.66[44] | -2.25[45] | -1.79[46] | -0.44[47] | -1.20[48] | -0.45[49] |
8 | IFNAR2 | Interferon alpha/beta receptor 2 | [50] | -1.06[51] | -1.16[52] | -0.30[53] | -1.46[54] | -1.20[55] | -1.13[56] |
9 | MYD88 | Myeloid differentiation primary response protein MyD88 | [57] | -0.03[58] | 0.26[59] | -0.12[60] | -1.11[61] | -0.54[62] | 0.44[63] |
10 | OAS1 | 2'-5'-oligoadenylate synthase 1 | [64] | -0.47[65] | -3.12[66] | -8.74[67] | -2.82[68] | -4.00[69] | -0.78[70] |
11 | IRF3 | Interferon regulatory factor 3 | [71] | 0.45[72] | 0.86[73] | 1.77[74] | 0.28[75] | 0.15[76] | -1.53[77] |
12 | MAPK14 | Mitogen-activated protein kinase 14 | [78] | 1.63[79] | 1.93[80] | 1.70[81] | 1.61[82] | 1.36[83] | 0.93[84] |
13 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [85] | 0.05[86] | 1.36[87] | 1.42[88] | 0.42[89] | 0.87[90] | -0.10[91] |
14 | IFNAR1 | Interferon alpha/beta receptor 1 | [92] | 0.21[93] | 0.92[94] | 0.82[95] | 0.92[96] | 1.18[97] | 2.08[98] |
15 | MAPK8 | Mitogen-activated protein kinase 8 | [99] | -1.29[100] | 0.36[101] | -0.59[102] | -0.97[103] | -0.84[104] | -0.86[105] |
16 | TBK1 | Serine/threonine-protein kinase TBK1 | [106] | -0.48[107] | 1.43[108] | 0.76[109] | 0.42[110] | 0.78[111] | 0.12[112] |
17 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [113] | 0.82[114] | 0.74[115] | 0.71[116] | -0.32[117] | 0.87[118] | 0.10[119] |
18 | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase | [120] | -0.16[121] | 0.03[122] | -1.76[123] | 0.94[124] | 0.73[125] | 0.43[126] |
19 | STAT2 | Signal transducer and activator of transcription 2 | [127] | 0.18[128] | 1.78[129] | 1.12[130] | 1.46[131] | 1.19[132] | 2.67[133] |
20 | TYK2 | Non-receptor tyrosine-protein kinase TYK2 | [134] | 1.29[135] | 1.89[136] | 2.20[137] | 0.68[138] | 1.87[139] | 1.64[140] |
21 | TICAM1 | TIR domain-containing adapter molecule 1 | [141] | -0.56[142] | -1.42[143] | -0.30[144] | -1.29[145] | 0.03[146] | -0.85[147] |
22 | IFIH1 | Interferon-induced helicase C domain-containing protein 1 | [148] | -1.81[149] | -1.49[150] | -5.42[151] | -1.30[152] | -0.79[153] | -0.10[154] |
23 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | [155] | 0.44[156] | 0.84[157] | 0.71[158] | 1.01[159] | 0.80[160] | 1.13[161] |
24 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [162] | 1.06[163] | 2.51[164] | 2.66[165] | 0.58[166] | 1.67[167] | 1.16[168] |
25 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [169] | 0.67[170] | 0.97[171] | 1.26[172] | 0.19[173] | 0.55[174] | 0.83[175] |
26 | DDX58 | Probable ATP-dependent RNA helicase DDX58 | [176] | -0.55[177] | -0.33[178] | -0.96[179] | -0.86[180] | -0.02[181] | 0.76[182] |
27 | OAS3 | 2'-5'-oligoadenylate synthase 3 | [183] | 2.42[184] | 0.17[185] | -5.91[186] | 1.06[187] | 2.08[188] | 0.97[189] |
28 | OAS2 | 2'-5'-oligoadenylate synthase 2 | [190] | -1.99[191] | -5.87[192] | -9.94[193] | -1.19[194] | -1.32[195] | 0.82[196] |
29 | MAVS | Mitochondrial antiviral-signaling protein | [197] | 4.43[198] | 4.28[199] | 4.07[200] | 3.66[201] | 3.53[202] | 3.00[203] |
30 | TRAF3 | TNF receptor-associated factor 3 | [204] | 3.04[205] | 2.70[206] | 2.49[207] | 2.76[208] | 3.44[209] | 1.57[210] |
31 | TRAF6 | TNF receptor-associated factor 6 | [211] | 1.24[212] | 1.37[213] | 2.12[214] | 1.59[215] | 1.32[216] | 2.56[217] |
32 | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | [218] | 1.87[219] | 1.98[220] | 1.06[221] | 2.49[222] | 2.31[223] | -0.59[224] |
33 | TLR7 | Toll-like receptor 7 | [225] | -0.68[226] | 0.35[227] | 0.84[228] | -0.65[229] | -0.81[230] | 0.92[231] |