WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_AUTOPHAGY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 BECN1 Beclin-1 [1] -0.85[2] -1.69[3] -1.59[4] -1.56[5] -1.66[6] -1.78[7]
2 ATG3 Ubiquitin-like-conjugating enzyme ATG3 [8] -2.34[9] -2.43[10] -1.73[11] -1.85[12] -1.24[13] -1.88[14]
3 ATG16L1 Autophagy-related protein 16-1 [15] 0.03[16] -0.56[17] -1.12[18] -0.54[19] -1.13[20] -1.34[21]
4 WIPI1 WD repeat domain phosphoinositide-interacting protein 1 [22] 0.08[23] 0.33[24] -0.44[25] -1.44[26] -0.80[27] -0.67[28]
5 ATG4A Cysteine protease ATG4A [29] -2.06[30] -2.28[31] -1.75[32] -1.66[33] -1.23[34] -0.62[35]
6 MAP1LC3A Microtubule-associated proteins 1A/1B light chain 3A [36] -9.05[37] -11.12[38] -10.34[39] -3.45[40] -1.58[41] -1.66[42]
7 ATG5 Autophagy protein 5 [43] -0.23[44] 0.17[45] -0.01[46] 0.57[47] 0.24[48] 0.12[49]
8 ATG13 Autophagy-related protein 13 [50] 2.03[51] 1.37[52] 1.76[53] -0.08[54] 0.93[55] 1.12[56]
9 ATG12 Ubiquitin-like protein ATG12 [57] 0.42[58] 0.69[59] 0.78[60] 1.25[61] 0.95[62] 0.71[63]
10 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [64] 0.37[65] 0.38[66] -0.38[67] 0.60[68] 0.73[69] -0.09[70]
11 MTOR Serine/threonine-protein kinase mTOR [71] 2.52[72] 2.91[73] 2.63[74] 2.47[75] 2.47[76] 2.73[77]
12 RB1CC1 RB1-inducible coiled-coil protein 1 [78] 0.27[79] 2.45[80] 1.61[81] 2.12[82] 1.57[83] 2.14[84]
13 ULK1 Serine/threonine-protein kinase ULK1 [85] 1.29[86] 0.95[87] 2.31[88] 1.77[89] 1.03[90] 1.17[91]
14 ZFYVE1 Zinc finger FYVE domain-containing protein 1 [92] 0.75[93] -0.06[94] -0.10[95] 1.03[96] 1.23[97] 0.77[98]
15 ATG7 Ubiquitin-like modifier-activating enzyme ATG7 [99] 0.98[100] -0.13[101] 0.76[102] 0.47[103] 1.25[104] 1.04[105]
16 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [106] 1.15[107] 0.59[108] 1.71[109] 1.46[110] 1.85[111] 2.15[112]
17 ATG10 Ubiquitin-like-conjugating enzyme ATG10 [113] -0.55[114] -0.79[115] -0.39[116] 0.05[117] -0.90[118] -0.56[119]
18 ATG16L2 Autophagy-related protein 16-2 [120] 0.42[121] 1.05[122] -0.15[123] -0.58[124] 1.49[125] 0.81[126]
19 ULK2 Serine/threonine-protein kinase ULK2 [127] -3.11[128] -2.76[129] 0.31[130] 3.08[131] 2.31[132] 1.68[133]
[1]
ref_hepatocyte BECN1
Mean 26.6
Standard deviation 14
Values 21 14 17 47 34
[2]
HepG2 BECN1
Mean 32.9
Standard deviation 2.3
Values 35 31
[3]
HepG2.C3A BECN1
Mean 25.2
Standard deviation 4.8
Values 29 22
[4]
HuH.7 BECN1
Mean 23.3
Standard deviation 2.3
Values 23 21 26
[5]
SNU475 BECN1
Mean 19.1
Standard deviation 2
Values 18 21
[6]
THLE BECN1
Mean 21.1
Standard deviation 3.3
Values 19 23
[7]
liver BECN1
Mean 18.2
Standard deviation 8.1
Values 9.2 14 23 27
[8]
ref_hepatocyte ATG3
Mean 23.7
Standard deviation 8.8
Values 17 22 22 19 39
[9]
HepG2 ATG3
Mean 10.5
Standard deviation 2.5
Values 12 8.7
[10]
HepG2.C3A ATG3
Mean 13.4
Standard deviation 2.5
Values 15 12
[11]
HuH.7 ATG3
Mean 18.8
Standard deviation 4.5
Values 23 14 19
[12]
SNU475 ATG3
Mean 14
Standard deviation 1.3
Values 15 13
[13]
THLE ATG3
Mean 25.3
Standard deviation 2.1
Values 24 27
[14]
liver ATG3
Mean 15.1
Standard deviation 7.5
Values 7.6 10 19 24
[15]
ref_hepatocyte ATG16L1
Mean 12.4
Standard deviation 8.2
Values 14 3.3 4.1 20 20
[16]
HepG2 ATG16L1
Mean 28.1
Standard deviation 1.2
Values 29 27
[17]
HepG2.C3A ATG16L1
Mean 25.7
Standard deviation 3.4
Values 28 23
[18]
HuH.7 ATG16L1
Mean 14.9
Standard deviation 3.4
Values 19 12 14
[19]
SNU475 ATG16L1
Mean 18
Standard deviation 1.7
Values 19 17
[20]
THLE ATG16L1
Mean 14.2
Standard deviation 0.11
Values 14 14
[21]
liver ATG16L1
Mean 11.5
Standard deviation 2.5
Values 10 15 8.6 12
[22]
ref_hepatocyte WIPI1
Mean 8.86
Standard deviation 6.3
Values 20 4.8 8.4 6.6 4.8
[23]
HepG2 WIPI1
Mean 20.9
Standard deviation 6.8
Values 16 26
[24]
HepG2.C3A WIPI1
Mean 34.1
Standard deviation 20
Values 20 48
[25]
HuH.7 WIPI1
Mean 17.2
Standard deviation 2.1
Values 16 20 16
[26]
SNU475 WIPI1
Mean 6.93
Standard deviation 3.6
Values 4.4 9.4
[27]
THLE WIPI1
Mean 12.8
Standard deviation 0.36
Values 13 13
[28]
liver WIPI1
Mean 13.1
Standard deviation 4.7
Values 9 9.8 14 19
[29]
ref_hepatocyte ATG4A
Mean 7.65
Standard deviation 3.1
Values 8.6 7.2 11 2.7 8.8
[30]
HepG2 ATG4A
Mean 4.1
Standard deviation 1.6
Values 5.2 3
[31]
HepG2.C3A ATG4A
Mean 4.79
Standard deviation 1.3
Values 5.7 3.9
[32]
HuH.7 ATG4A
Mean 6
Standard deviation 0.58
Values 6.5 6.1 5.4
[33]
SNU475 ATG4A
Mean 5.15
Standard deviation 0.14
Values 5.1 5.2
[34]
THLE ATG4A
Mean 8.22
Standard deviation 0.48
Values 8.6 7.9
[35]
liver ATG4A
Mean 11.7
Standard deviation 4.4
Values 7.3 8.8 14 16
[36]
ref_hepatocyte MAP1LC3A
Mean 7.47
Standard deviation 7.7
Values 6.6 20 6.7 0.12 3.6
[37]
HepG2 MAP1LC3A
Mean 0.0315
Standard deviation 0.004
Values 0.034 0.029
[38]
HepG2.C3A MAP1LC3A
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[39]
HuH.7 MAP1LC3A
Mean 0.0152
Standard deviation 0.017
Values 0 0.013 0.033
[40]
SNU475 MAP1LC3A
Mean 1.45
Standard deviation 0.48
Values 1.1 1.8
[41]
THLE MAP1LC3A
Mean 6.29
Standard deviation 0.45
Values 6.6 6
[42]
liver MAP1LC3A
Mean 5.54
Standard deviation 6.3
Values 0.61 0.49 14 7.4
[43]
ref_hepatocyte ATG5
Mean 6.42
Standard deviation 2
Values 6.5 8.3 8.4 4.4 4.5
[44]
HepG2 ATG5
Mean 12.2
Standard deviation 4.5
Values 15 9
[45]
HepG2.C3A ATG5
Mean 22.1
Standard deviation 5.1
Values 26 18
[46]
HuH.7 ATG5
Mean 16.7
Standard deviation 1.4
Values 18 16 16
[47]
SNU475 ATG5
Mean 20.3
Standard deviation 1.9
Values 19 22
[48]
THLE ATG5
Mean 19
Standard deviation 0.43
Values 19 19
[49]
liver ATG5
Mean 16.3
Standard deviation 4.6
Values 11 15 20 20
[50]
ref_hepatocyte ATG13
Mean 4.93
Standard deviation 1.7
Values 4.9 4.9 6.9 2.3 5.6
[51]
HepG2 ATG13
Mean 44.9
Standard deviation 2.2
Values 46 43
[52]
HepG2.C3A ATG13
Mean 39
Standard deviation 7.5
Values 34 44
[53]
HuH.7 ATG13
Mean 44.1
Standard deviation 2.3
Values 42 45 46
[54]
SNU475 ATG13
Mean 9.91
Standard deviation 1.8
Values 8.7 11
[55]
THLE ATG13
Mean 23.7
Standard deviation 4.2
Values 21 27
[56]
liver ATG13
Mean 25.1
Standard deviation 8.4
Values 19 17 32 33
[57]
ref_hepatocyte ATG12
Mean 4.73
Standard deviation 0.81
Values 3.6 4.5 4.5 5.6 5.4
[58]
HepG2 ATG12
Mean 14.1
Standard deviation 2.6
Values 16 12
[59]
HepG2.C3A ATG12
Mean 23.3
Standard deviation 1.9
Values 25 22
[60]
HuH.7 ATG12
Mean 21.4
Standard deviation 1.1
Values 23 21 20
[61]
SNU475 ATG12
Mean 23.9
Standard deviation 3.1
Values 22 26
[62]
THLE ATG12
Mean 22.9
Standard deviation 1.3
Values 22 24
[63]
liver ATG12
Mean 18.2
Standard deviation 8
Values 12 11 25 25
[64]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 2.3 3 3.8 8 5.9
[65]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 16 11
[66]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 19 17
[67]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 7.5 11 9.1
[68]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 12 17
[69]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[70]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 11 15 6.9 6.8
[71]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[72]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[73]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[74]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[75]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[76]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[77]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[78]
ref_hepatocyte RB1CC1
Mean 3.31
Standard deviation 1.7
Values 1.7 2.1 2.6 5.6 4.5
[79]
HepG2 RB1CC1
Mean 8.89
Standard deviation 1.4
Values 9.9 7.9
[80]
HepG2.C3A RB1CC1
Mean 55.2
Standard deviation 1.3
Values 54 56
[81]
HuH.7 RB1CC1
Mean 26.6
Standard deviation 9.4
Values 21 37 22
[82]
SNU475 RB1CC1
Mean 30.5
Standard deviation 1.9
Values 29 32
[83]
THLE RB1CC1
Mean 24.7
Standard deviation 8.3
Values 31 19
[84]
liver RB1CC1
Mean 34.2
Standard deviation 7.1
Values 33 42 35 25
[85]
ref_hepatocyte ULK1
Mean 3.19
Standard deviation 0.97
Values 3.8 2.7 4.6 2.2 2.6
[86]
HepG2 ULK1
Mean 17.5
Standard deviation 3
Values 15 20
[87]
HepG2.C3A ULK1
Mean 18.9
Standard deviation 12
Values 10 27
[88]
HuH.7 ULK1
Mean 41.8
Standard deviation 6.6
Values 38 49 38
[89]
SNU475 ULK1
Mean 23
Standard deviation 7.3
Values 18 28
[90]
THLE ULK1
Mean 16.5
Standard deviation 0.85
Values 16 17
[91]
liver ULK1
Mean 16.8
Standard deviation 11
Values 22 7.2 29 8.9
[92]
ref_hepatocyte ZFYVE1
Mean 2.29
Standard deviation 1
Values 1.2 3 3.5 1.3 2.5
[93]
HepG2 ZFYVE1
Mean 8.58
Standard deviation 0.73
Values 9.1 8.1
[94]
HepG2.C3A ZFYVE1
Mean 6.69
Standard deviation 1.6
Values 5.5 7.9
[95]
HuH.7 ZFYVE1
Mean 5.63
Standard deviation 1.9
Values 3.8 7.7 5.3
[96]
SNU475 ZFYVE1
Mean 9.92
Standard deviation 2.6
Values 8 12
[97]
THLE ZFYVE1
Mean 13.5
Standard deviation 1.2
Values 13 14
[98]
liver ZFYVE1
Mean 9.13
Standard deviation 2.8
Values 5.6 8.2 11 11
[99]
ref_hepatocyte ATG7
Mean 1.98
Standard deviation 0.67
Values 2.5 2.4 2.3 0.88 1.8
[100]
HepG2 ATG7
Mean 8.71
Standard deviation 0.27
Values 8.5 8.9
[101]
HepG2.C3A ATG7
Mean 5.51
Standard deviation 0.43
Values 5.8 5.2
[102]
HuH.7 ATG7
Mean 8.79
Standard deviation 1.8
Values 9.1 6.9 10
[103]
SNU475 ATG7
Mean 5.82
Standard deviation 0.2
Values 6 5.7
[104]
THLE ATG7
Mean 11.8
Standard deviation 1.9
Values 10 13
[105]
liver ATG7
Mean 9.51
Standard deviation 2.7
Values 11 12 6.5 8.1
[106]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.2 3.2 2.4 1.4 1.7
[107]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 12 7.4
[108]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 10 7.8
[109]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 16 14 20
[110]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[111]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[112]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 27 27 15 12
[113]
ref_hepatocyte ATG10
Mean 1.86
Standard deviation 0.78
Values 1.5 1.5 1.9 1.2 3.2
[114]
HepG2 ATG10
Mean 2.85
Standard deviation 0.7
Values 3.3 2.3
[115]
HepG2.C3A ATG10
Mean 3.3
Standard deviation 1.3
Values 4.2 2.4
[116]
HuH.7 ATG10
Mean 3.75
Standard deviation 0.42
Values 4 3.3 4
[117]
SNU475 ATG10
Mean 4.08
Standard deviation 1.2
Values 3.2 4.9
[118]
THLE ATG10
Mean 2.51
Standard deviation 0.4
Values 2.2 2.8
[119]
liver ATG10
Mean 2.98
Standard deviation 1.3
Values 1.9 1.8 4.4 3.8
[120]
ref_hepatocyte ATG16L2
Mean 0.783
Standard deviation 0.54
Values 0.46 1.4 1.3 0.44 0.27
[121]
HepG2 ATG16L2
Mean 2.34
Standard deviation 0.33
Values 2.1 2.6
[122]
HepG2.C3A ATG16L2
Mean 4.96
Standard deviation 2.7
Values 3 6.9
[123]
HuH.7 ATG16L2
Mean 1.85
Standard deviation 0.48
Values 2.3 1.8 1.4
[124]
SNU475 ATG16L2
Mean 1.11
Standard deviation 0.36
Values 0.86 1.4
[125]
THLE ATG16L2
Mean 5.53
Standard deviation 2.5
Values 7.3 3.8
[126]
liver ATG16L2
Mean 3.21
Standard deviation 1.2
Values 4.3 2.5 4.1 2
[127]
ref_hepatocyte ULK2
Mean 0.556
Standard deviation 0.3
Values 0.76 0.69 0.65 0.026 0.66
[128]
HepG2 ULK2
Mean 0.143
Standard deviation 0.033
Values 0.12 0.17
[129]
HepG2.C3A ULK2
Mean 0.25
Standard deviation 0.01
Values 0.26 0.24
[130]
HuH.7 ULK2
Mean 1.82
Standard deviation 0.22
Values 1.7 2.1 1.7
[131]
SNU475 ULK2
Mean 9.97
Standard deviation 5.4
Values 6.1 14
[132]
THLE ULK2
Mean 6.93
Standard deviation 0.73
Values 7.4 6.4
[133]
liver ULK2
Mean 4.19
Standard deviation 1.7
Values 5.1 6.1 2.3 3.3