WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_APOPTOSIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 [1] -0.79[2] -0.68[3] -0.48[4] 0.11[5] 0.61[6] 0.47[7]
2 AKT1 RAC-alpha serine/threonine-protein kinase [8] -0.56[9] -0.63[10] -1.69[11] -0.10[12] -0.07[13] 0.14[14]
3 BCL2L1 Bcl-2-like protein 1 [15] 1.50[16] 1.05[17] 2.02[18] -0.66[19] -0.27[20] -0.43[21]
4 BAX Apoptosis regulator BAX [22] -0.31[23] -0.94[24] -1.39[25] -1.65[26] -1.26[27] -3.57[28]
5 BAD Bcl2-associated agonist of cell death [29] -2.31[30] -2.01[31] -2.95[32] -1.11[33] -0.70[34] -1.04[35]
6 CASP3 Caspase-3 [36] -0.51[37] 0.34[38] -2.20[39] -0.94[40] 0.06[41] -0.42[42]
7 BID BH3-interacting domain death agonist [43] -0.91[44] -0.64[45] -1.01[46] -0.34[47] -0.86[48] 0.56[49]
8 CASP7 Caspase-7 [50] -0.95[51] -1.15[52] -0.70[53] -0.94[54] -0.73[55] -0.10[56]
9 FADD FAS-associated death domain protein [57] -0.60[58] -1.14[59] -0.41[60] 1.89[61] -0.29[62] -1.39[63]
10 CASP8 Caspase-8 [64] -0.62[65] 0.12[66] -0.70[67] -0.13[68] -0.86[69] -1.03[70]
11 MAPK14 Mitogen-activated protein kinase 14 [71] 0.83[72] 1.07[73] 0.66[74] 1.64[75] 1.12[76] 1.67[77]
12 MAPK13 Mitogen-activated protein kinase 13 [78] 1.70[79] 2.27[80] -0.40[81] -1.93[82] -0.40[83] -1.33[84]
13 BBC3 Bcl-2-binding component 3 [85] 0.10[86] 0.15[87] -0.34[88] -2.85[89] -2.08[90] -3.95[91]
14 CASP9 Caspase-9 [92] -0.49[93] 0.64[94] -0.23[95] 0.20[96] -0.48[97] -0.15[98]
15 BCL2L11 Bcl-2-like protein 11 [99] 0.86[100] 1.04[101] 1.38[102] 1.82[103] 0.80[104] 2.37[105]
16 APAF1 Apoptotic protease-activating factor 1 [106] 1.02[107] 1.61[108] 1.87[109] 2.58[110] 1.69[111] 1.87[112]
17 MAPK12 Mitogen-activated protein kinase 12 [113] 2.18[114] 2.01[115] 3.13[116] 1.44[117] 2.70[118] -0.52[119]
18 MAPK11 Mitogen-activated protein kinase 11 [120] -0.81[121] -0.75[122] -1.63[123] 0.31[124] 2.31[125] 0.55[126]
19 TNF Tumor necrosis factor [127] 0.46[128] -1.51[129] -6.10[130] -2.27[131] -5.48[132] -1.51[133]
20 BCL2 Apoptosis regulator Bcl-2 [134] -3.50[135] 2.08[136] -5.32[137] 1.73[138] 1.45[139] 3.62[140]
21 FASLG Tumor necrosis factor ligand superfamily member 6 [141] -4.45[142] -2.41[143] -6.38[144] [145] [146] 0.97[147]
22 MIR3191 [148] [149] [150] [151] [152] [153] [154]
[1]
ref_hepatocyte MCL1
Mean 51.6
Standard deviation 21
Values 68 45 71 19 55
[2]
HepG2 MCL1
Mean 103
Standard deviation 11
Values 1.1e+02 95
[3]
HepG2.C3A MCL1
Mean 88.2
Standard deviation 15
Values 78 99
[4]
HuH.7 MCL1
Mean 96.5
Standard deviation 9.6
Values 89 1.1e+02 94
[5]
SNU475 MCL1
Mean 105
Standard deviation 9
Values 99 1.1e+02
[6]
THLE MCL1
Mean 166
Standard deviation 39
Values 1.4e+02 1.9e+02
[7]
liver MCL1
Mean 77.6
Standard deviation 52
Values 1.4e+02 1.1e+02 41 28
[8]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[9]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[10]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[11]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[12]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[13]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[14]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[15]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 34 16 23 16 44
[16]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 2.2e+02 3e+02
[17]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[18]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.2e+02 2.1e+02 3.1e+02
[19]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 35 29
[20]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[21]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 14 9.8 31 31
[22]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 34 11 27 30 21
[23]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 58 80
[24]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 33 38
[25]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 34 14 26
[26]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 16 14
[27]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[28]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 1.4 2.5 2.3 2.9
[29]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 6.7 27 28 5.4 16
[30]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 12 11
[31]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 12 10
[32]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5.5 6.4 5
[33]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 13 16
[34]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[35]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 3.7 3.7 16 12
[36]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 6.8 5.1 4.9 33 13
[37]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 36 25
[38]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 59 27
[39]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 7.8 7.5 5.9
[40]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 12 13
[41]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[42]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 6.1 9 9.5 16
[43]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 17 12 15 4.5 12
[44]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 23 22
[45]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 25 18
[46]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 21 12 15
[47]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 17 19
[48]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[49]
liver BID
Mean 19.7
Standard deviation 11
Values 10 9.4 30 29
[50]
ref_hepatocyte CASP7
Mean 10
Standard deviation 4.1
Values 15 6 7.6 7.8 14
[51]
HepG2 CASP7
Mean 17.9
Standard deviation 4
Values 21 15
[52]
HepG2.C3A CASP7
Mean 12.4
Standard deviation 4
Values 15 9.5
[53]
HuH.7 CASP7
Mean 16.1
Standard deviation 1.8
Values 18 15 15
[54]
SNU475 CASP7
Mean 9.89
Standard deviation 0.26
Values 9.7 10
[55]
THLE CASP7
Mean 12.8
Standard deviation 0.29
Values 13 13
[56]
liver CASP7
Mean 10.2
Standard deviation 3.1
Values 10 6.6 14 9.7
[57]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 20 5.1 6.3 3.8 12
[58]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 18 24
[59]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 13 10
[60]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 22 16 16
[61]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 58 73
[62]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[63]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 5.1 4.9 2.5 3
[64]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 8.9 2.8 1.9 18 13
[65]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 18 22
[66]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 35 17
[67]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 18 11 14
[68]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 15 16
[69]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[70]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 5 5.2 3.4 5.3
[71]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[72]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[73]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[74]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[75]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[76]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[77]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[78]
ref_hepatocyte MAPK13
Mean 5.46
Standard deviation 4.5
Values 9.1 0.39 2.7 11 4
[79]
HepG2 MAPK13
Mean 61.1
Standard deviation 22
Values 46 77
[80]
HepG2.C3A MAPK13
Mean 72
Standard deviation 5.6
Values 68 76
[81]
HuH.7 MAPK13
Mean 10.8
Standard deviation 1.6
Values 9.2 12 11
[82]
SNU475 MAPK13
Mean 2.71
Standard deviation 2.1
Values 4.2 1.2
[83]
THLE MAPK13
Mean 8.71
Standard deviation 2.1
Values 7.2 10
[84]
liver MAPK13
Mean 2.36
Standard deviation 1.5
Values 1.8 1.5 4.6 1.5
[85]
ref_hepatocyte BBC3
Mean 4.09
Standard deviation 4.3
Values 11 1.3 3.2 3.6 0.92
[86]
HepG2 BBC3
Mean 15.1
Standard deviation 11
Values 7 23
[87]
HepG2.C3A BBC3
Mean 12.4
Standard deviation 9.8
Values 5.5 19
[88]
HuH.7 BBC3
Mean 8.39
Standard deviation 3.1
Values 7.8 12 5.7
[89]
SNU475 BBC3
Mean 1.08
Standard deviation 0.44
Values 0.77 1.4
[90]
THLE BBC3
Mean 2.04
Standard deviation 0.082
Values 2.1 2
[91]
liver BBC3
Mean 0.288
Standard deviation 0.11
Values 0.44 0.3 0.24 0.18
[92]
ref_hepatocyte CASP9
Mean 2.59
Standard deviation 1
Values 2 4.4 2.7 1.9 1.9
[93]
HepG2 CASP9
Mean 6.38
Standard deviation 0.81
Values 7 5.8
[94]
HepG2.C3A CASP9
Mean 11.1
Standard deviation 0.21
Values 11 11
[95]
HuH.7 CASP9
Mean 5.76
Standard deviation 1.5
Values 6.6 4.1 6.7
[96]
SNU475 CASP9
Mean 5.65
Standard deviation 0.92
Values 5 6.3
[97]
THLE CASP9
Mean 3.94
Standard deviation 0.43
Values 3.6 4.2
[98]
liver CASP9
Mean 2.54
Standard deviation 1.2
Values 1.6 1.9 2.4 4.2
[99]
ref_hepatocyte BCL2L11
Mean 1.6
Standard deviation 0.72
Values 1.7 1.5 2 2.4 0.45
[100]
HepG2 BCL2L11
Mean 10.1
Standard deviation 0.76
Values 9.5 11
[101]
HepG2.C3A BCL2L11
Mean 9.01
Standard deviation 0.3
Values 9.2 8.8
[102]
HuH.7 BCL2L11
Mean 10.8
Standard deviation 1
Values 9.7 12 11
[103]
SNU475 BCL2L11
Mean 10.7
Standard deviation 3
Values 8.6 13
[104]
THLE BCL2L11
Mean 5.92
Standard deviation 0.75
Values 5.4 6.4
[105]
liver BCL2L11
Mean 9.03
Standard deviation 4.2
Values 15 6.5 7.8 6.5
[106]
ref_hepatocyte APAF1
Mean 1.36
Standard deviation 0.48
Values 1.2 1.1 0.79 1.9 1.8
[107]
HepG2 APAF1
Mean 9.46
Standard deviation 4.9
Values 13 6
[108]
HepG2.C3A APAF1
Mean 11.3
Standard deviation 2.5
Values 13 9.5
[109]
HuH.7 APAF1
Mean 12.9
Standard deviation 2.1
Values 12 12 15
[110]
SNU475 APAF1
Mean 15.4
Standard deviation 1.9
Values 14 17
[111]
THLE APAF1
Mean 9.25
Standard deviation 1.4
Values 8.2 10
[112]
liver APAF1
Mean 5.4
Standard deviation 3.4
Values 8.2 8.5 2.4 2.5
[113]
ref_hepatocyte MAPK12
Mean 0.743
Standard deviation 0.94
Values 0.21 0.28 0.41 2.4 0.4
[114]
HepG2 MAPK12
Mean 11.6
Standard deviation 3.6
Values 9 14
[115]
HepG2.C3A MAPK12
Mean 8.16
Standard deviation 0.15
Values 8.3 8.1
[116]
HuH.7 MAPK12
Mean 16.9
Standard deviation 6.7
Values 23 9.7 18
[117]
SNU475 MAPK12
Mean 3.82
Standard deviation 1.9
Values 2.5 5.2
[118]
THLE MAPK12
Mean 10.2
Standard deviation 1.3
Values 9.2 11
[119]
liver MAPK12
Mean 0.564
Standard deviation 0.13
Values 0.69 0.43 0.47 0.67
[120]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0.22 0.64 0.71 0 0.34
[121]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.88 0.62
[122]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.71 0.53
[123]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.49 0.2 0.28
[124]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 0.66 1.1
[125]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[126]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.75 0.49 0.96 0.23
[127]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[128]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[129]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[130]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[131]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[132]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[133]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[134]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.15 0.2 0.12 0.019 0
[135]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.026 0.034
[136]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 0.99 1.3
[137]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[138]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.68 0.55
[139]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[140]
liver BCL2
Mean 1.31
Standard deviation 1
Values 2.5 1.8 0.49 0.49
[141]
ref_hepatocyte FASLG
Mean 0.0683
Standard deviation 0.15
Values 0 0.34 0 0 0
[142]
HepG2 FASLG
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[143]
HepG2.C3A FASLG
Mean 0.035
Standard deviation 0.019
Values 0.021 0.049
[144]
HuH.7 FASLG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[145]
SNU475 FASLG
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE FASLG
Mean 0
Standard deviation 0
Values 0 0
[147]
liver FASLG
Mean 0.145
Standard deviation 0.073
Values 0.15 0.043 0.19 0.21
[148]
ref_hepatocyte MIR3191
Missing
[149]
HepG2 MIR3191
Missing
[150]
HepG2.C3A MIR3191
Missing
[151]
HuH.7 MIR3191
Missing
[152]
SNU475 MIR3191
Missing
[153]
THLE MIR3191
Missing
[154]
liver MIR3191
Missing