WP_HFE_EFFECT_ON_HEPCIDIN_PRODUCTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HAMP Hepcidin [1] -1.97[2] -5.75[3] -10.58[4] -10.42[5] -11.81[6] -0.49[7]
2 ID1 DNA-binding protein inhibitor ID-1 [8] 4.57[9] 4.93[10] 5.13[11] 4.82[12] 4.96[13] 1.64[14]
3 TMPRSS6 Transmembrane protease serine 6 [15] 0.80[16] 2.97[17] -1.29[18] -4.98[19] -3.24[20] 3.72[21]
4 SMAD7 Mothers against decapentaplegic homolog 7 [22] 4.45[23] 3.66[24] 3.24[25] 5.09[26] 4.69[27] 2.84[28]
5 HFE Hereditary hemochromatosis protein [29] 2.15[30] 2.79[31] 3.43[32] 5.58[33] 4.84[34] 3.61[35]
6 BMP6 Bone morphogenetic protein 6 [36] 2.74[37] 1.12[38] 0.63[39] 3.73[40] 2.38[41] 4.42[42]
7 HJV [43] [44] [45] [46] [47] [48] [49]
[1]
ref_hepatocyte HAMP
Mean 916
Standard deviation 1.3e+03
Values 37 2.8e+03 1.7e+03 3.5 0
[2]
HepG2 HAMP
Mean 85.9
Standard deviation 25
Values 68 1e+02
[3]
HepG2.C3A HAMP
Mean 2.59
Standard deviation 0.6
Values 3 2.2
[4]
HuH.7 HAMP
Mean 0.0581
Standard deviation 0.036
Values 0.019 0.09 0.066
[5]
SNU475 HAMP
Mean 0.054
Standard deviation 0.055
Values 0.015 0.093
[6]
THLE HAMP
Mean 0.0248
Standard deviation 0.01
Values 0.018 0.032
[7]
liver HAMP
Mean 130
Standard deviation 1.4e+02
Values 9.1 2.9 2.4e+02 2.7e+02
[8]
ref_hepatocyte ID1
Mean 25.6
Standard deviation 18
Values 6 19 54 18 32
[9]
HepG2 ID1
Mean 223
Standard deviation 36
Values 2e+02 2.5e+02
[10]
HepG2.C3A ID1
Mean 119
Standard deviation 49
Values 1.5e+02 85
[11]
HuH.7 ID1
Mean 86.7
Standard deviation 43
Values 1.2e+02 39 97
[12]
SNU475 ID1
Mean 58.5
Standard deviation 3.9
Values 56 61
[13]
THLE ID1
Mean 77.8
Standard deviation 7.4
Values 73 83
[14]
liver ID1
Mean 15.9
Standard deviation 2
Values 18 13 16 16
[15]
ref_hepatocyte TMPRSS6
Mean 12.5
Standard deviation 17
Values 1.7 39 21 0.92 0.11
[16]
HepG2 TMPRSS6
Mean 8
Standard deviation 0.9
Values 7.4 8.6
[17]
HepG2.C3A TMPRSS6
Mean 15
Standard deviation 6.5
Values 10 20
[18]
HuH.7 TMPRSS6
Mean 0.494
Standard deviation 0.36
Values 0.31 0.91 0.26
[19]
SNU475 TMPRSS6
Mean 0.0321
Standard deviation 0.019
Values 0.046 0.019
[20]
THLE TMPRSS6
Mean 0.129
Standard deviation 0.069
Values 0.18 0.08
[21]
liver TMPRSS6
Mean 32.7
Standard deviation 21
Values 28 14 62 28
[22]
ref_hepatocyte SMAD7
Mean 3.77
Standard deviation 2.9
Values 2.4 1.3 1.7 5.6 7.9
[23]
HepG2 SMAD7
Mean 30.1
Standard deviation 6.8
Values 25 35
[24]
HepG2.C3A SMAD7
Mean 7.28
Standard deviation 2.6
Values 9.1 5.5
[25]
HuH.7 SMAD7
Mean 3.45
Standard deviation 0.58
Values 3.1 4.1 3.1
[26]
SNU475 SMAD7
Mean 10.4
Standard deviation 2.4
Values 8.7 12
[27]
THLE SMAD7
Mean 9.45
Standard deviation 1.3
Values 8.6 10
[28]
liver SMAD7
Mean 5.35
Standard deviation 1.1
Values 4.8 6.5 4.2 6
[29]
ref_hepatocyte HFE
Mean 2.05
Standard deviation 1.4
Values 0.46 2.9 2.3 0.87 3.8
[30]
HepG2 HFE
Mean 3.33
Standard deviation 0.12
Values 3.4 3.2
[31]
HepG2.C3A HFE
Mean 2.17
Standard deviation 0.6
Values 2.6 1.7
[32]
HuH.7 HFE
Mean 2.14
Standard deviation 0.36
Values 2.2 1.7 2.4
[33]
SNU475 HFE
Mean 7.92
Standard deviation 5
Values 4.4 11
[34]
THLE HFE
Mean 5.71
Standard deviation 1.4
Values 4.7 6.7
[35]
liver HFE
Mean 4.97
Standard deviation 0.69
Values 4.5 5.7 4.3 5.4
[36]
ref_hepatocyte BMP6
Mean 0.569
Standard deviation 0.4
Values 0.99 0.16 0.3 1 0.38
[37]
HepG2 BMP6
Mean 1.4
Standard deviation 1.6
Values 0.27 2.5
[38]
HepG2.C3A BMP6
Mean 0.189
Standard deviation 0.02
Values 0.2 0.17
[39]
HuH.7 BMP6
Mean 0.0853
Standard deviation 0.06
Values 0.15 0.032 0.074
[40]
SNU475 BMP6
Mean 0.611
Standard deviation 0.26
Values 0.8 0.43
[41]
THLE BMP6
Mean 0.288
Standard deviation 0.0061
Values 0.28 0.29
[42]
liver BMP6
Mean 2.41
Standard deviation 1.7
Values 4.1 3.6 0.56 1.5
[43]
ref_hepatocyte HJV
Missing
[44]
HepG2 HJV
Missing
[45]
HepG2.C3A HJV
Missing
[46]
HuH.7 HJV
Missing
[47]
SNU475 HJV
Missing
[48]
THLE HJV
Missing
[49]
liver HJV
Missing