WP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [1] | -1.19[2] | -1.12[3] | -0.49[4] | -0.93[5] | -0.98[6] | -1.20[7] |
2 | CTTN | Src substrate cortactin | [8] | -0.63[9] | -1.01[10] | -0.75[11] | 0.99[12] | -1.14[13] | -0.66[14] |
3 | JUN | Transcription factor AP-1 | [15] | -1.28[16] | -2.43[17] | -2.24[18] | -2.65[19] | -2.11[20] | -2.05[21] |
4 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [22] | 0.05[23] | -0.95[24] | -3.72[25] | -2.93[26] | -0.41[27] | -2.07[28] |
5 | AKT1 | RAC-alpha serine/threonine-protein kinase | [29] | -0.71[30] | -0.55[31] | -1.71[32] | -1.00[33] | -1.01[34] | -0.48[35] |
6 | STAT3 | Signal transducer and activator of transcription 3 | [36] | -0.24[37] | -1.35[38] | -0.69[39] | -0.70[40] | -1.46[41] | 2.17[42] |
7 | MYC | Myc proto-oncogene protein | [43] | -0.36[44] | -0.31[45] | -2.42[46] | -3.74[47] | -1.40[48] | -2.24[49] |
8 | BCL2L1 | Bcl-2-like protein 1 | [50] | 1.35[51] | 1.12[52] | 2.01[53] | -1.56[54] | -1.21[55] | -1.06[56] |
9 | HIF1A | Hypoxia-inducible factor 1-alpha | [57] | -0.95[58] | -0.89[59] | -0.17[60] | 1.34[61] | 1.69[62] | -1.04[63] |
10 | CCND1 | G1/S-specific cyclin-D1 | [64] | 2.26[65] | 0.15[66] | 0.90[67] | 0.93[68] | -0.58[69] | 0.82[70] |
11 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [71] | -0.35[72] | 0.48[73] | 0.35[74] | -0.06[75] | 0.54[76] | 1.02[77] |
12 | GRB2 | Growth factor receptor-bound protein 2 | [78] | 0.40[79] | 0.63[80] | 0.67[81] | -0.39[82] | -0.51[83] | 0.06[84] |
13 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | [85] | -3.91[86] | -2.49[87] | -4.97[88] | -4.07[89] | -0.33[90] | -2.32[91] |
14 | VEGFA | Vascular endothelial growth factor A | [92] | 0.42[93] | 2.15[94] | 0.68[95] | -0.51[96] | 0.17[97] | 0.54[98] |
15 | JAK1 | Tyrosine-protein kinase JAK1 | [99] | -0.28[100] | -0.40[101] | -0.30[102] | -0.32[103] | 0.29[104] | 1.29[105] |
16 | CD44 | CD44 antigen | [106] | -7.86[107] | -8.97[108] | -2.62[109] | 0.81[110] | 1.24[111] | -1.52[112] |
17 | CASP3 | Caspase-3 | [113] | -0.66[114] | 0.41[115] | -2.22[116] | -1.84[117] | -0.88[118] | -1.04[119] |
18 | UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | [120] | -6.50[121] | -6.05[122] | 1.72[123] | 2.01[124] | 2.33[125] | -5.86[126] |
19 | RRM2 | Ribonucleoside-diphosphate reductase subunit M2 | [127] | 0.79[128] | 1.31[129] | 0.73[130] | 1.16[131] | 1.17[132] | -1.08[133] |
20 | IL6R | Interleukin-6 receptor subunit alpha | [134] | -1.01[135] | -0.29[136] | -1.19[137] | -1.82[138] | -5.95[139] | 1.42[140] |
21 | MMP1 | Interstitial collagenase | [141] | -5.96[142] | -9.34[143] | [144] | -2.70[145] | -3.18[146] | -12.37[147] |
22 | CASP7 | Caspase-7 | [148] | -1.10[149] | -1.08[150] | -0.71[151] | -1.84[152] | -1.67[153] | -0.72[154] |
23 | MAPK14 | Mitogen-activated protein kinase 14 | [155] | 0.68[156] | 1.14[157] | 0.64[158] | 0.74[159] | 0.18[160] | 1.05[161] |
24 | VAV2 | Guanine nucleotide exchange factor VAV2 | [162] | 0.51[163] | 1.15[164] | 0.56[165] | -1.48[166] | -1.09[167] | 0.27[168] |
25 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | [169] | 0.78[170] | 1.62[171] | 1.50[172] | -0.27[173] | 0.53[174] | -2.55[175] |
26 | MAPK8 | Mitogen-activated protein kinase 8 | [176] | -2.24[177] | -0.44[178] | -1.64[179] | -1.85[180] | -2.02[181] | -0.75[182] |
27 | SOS1 | Son of sevenless homolog 1 | [183] | -0.89[184] | 1.03[185] | 0.46[186] | -0.10[187] | -0.90[188] | 0.30[189] |
28 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [190] | -0.12[191] | -0.05[192] | -0.34[193] | -1.19[194] | -0.32[195] | 0.21[196] |
29 | SMAD3 | Mothers against decapentaplegic homolog 3 | [197] | 1.14[198] | 0.92[199] | 1.07[200] | 0.85[201] | 1.70[202] | -0.03[203] |
30 | HNF1A | Hepatocyte nuclear factor 1-alpha | [204] | 0.12[205] | 0.84[206] | 1.45[207] | -4.32[208] | -5.20[209] | -0.04[210] |
31 | TP53 | Cellular tumor antigen p53 | [211] | 0.84[212] | 0.80[213] | 1.48[214] | 0.35[215] | -0.02[216] | -0.28[217] |
32 | TGFBR1 | TGF-beta receptor type-1 | [218] | -0.46[219] | 0.15[220] | -0.42[221] | -0.60[222] | 0.47[223] | 1.09[224] |
33 | MAPK3 | Mitogen-activated protein kinase 3 | [225] | 1.06[226] | 1.49[227] | 1.45[228] | -0.52[229] | -0.53[230] | -1.28[231] |
34 | SMAD4 | Mothers against decapentaplegic homolog 4 | [232] | 0.60[233] | 1.62[234] | 1.51[235] | 0.96[236] | 1.30[237] | 2.55[238] |
35 | MYOF | Myoferlin | [239] | -0.71[240] | -3.15[241] | -0.32[242] | 2.95[243] | 1.43[244] | -0.16[245] |
36 | CASP9 | Caspase-9 | [246] | -0.64[247] | 0.71[248] | -0.25[249] | -0.70[250] | -1.42[251] | -0.78[252] |
37 | TGFB1 | Transforming growth factor beta-1 | [253] | 2.68[254] | 2.03[255] | -0.80[256] | 2.89[257] | 2.09[258] | -1.47[259] |
38 | BRCA1 | Breast cancer type 1 susceptibility protein | [260] | 0.88[261] | 2.52[262] | 2.83[263] | 1.20[264] | 1.69[265] | 1.44[266] |
39 | IL6 | Interleukin-6 | [267] | -9.24[268] | [269] | -5.32[270] | -1.80[271] | 0.68[272] | [273] |
40 | PODXL | Podocalyxin | [274] | -1.25[275] | -2.59[276] | -1.31[277] | -0.08[278] | -1.69[279] | 1.31[280] |
41 | NOS2 | Nitric oxide synthase, inducible | [281] | -0.77[282] | [283] | -6.70[284] | -5.80[285] | -6.72[286] | -7.55[287] |
42 | COL4A2 | Collagen alpha-2(IV) chain | [288] | -0.86[289] | -0.15[290] | -2.93[291] | 6.24[292] | 6.11[293] | 4.92[294] |
43 | E2F2 | Transcription factor E2F2 | [295] | 3.45[296] | 4.74[297] | 4.17[298] | 3.11[299] | 3.40[300] | 1.18[301] |
44 | FASLG | Tumor necrosis factor ligand superfamily member 6 | [302] | -4.61[303] | -2.34[304] | -6.39[305] | [306] | [307] | 0.35[308] |
45 | FRZB | Secreted frizzled-related protein 3 | [309] | -2.69[310] | 0.35[311] | 1.03[312] | 0.54[313] | -0.25[314] | 2.76[315] |
46 | LEF1 | Lymphoid enhancer-binding factor 1 | [316] | 1.86[317] | -4.67[318] | 3.16[319] | 0.14[320] | -1.60[321] | 0.85[322] |
47 | PTGS2 | Prostaglandin G/H synthase 2 | [323] | [324] | -3.02[325] | -2.85[326] | 1.92[327] | 7.70[328] | 2.60[329] |
48 | MIR744 | [330] | [331] | [332] | [333] | [334] | [335] | [336] | |
49 | CXCR1 | C-X-C chemokine receptor type 1 | [337] | [338] | [339] | [340] | [341] | [342] | [343] |
50 | CXCL8 | Interleukin-8 | [344] | [345] | [346] | [347] | [348] | [349] | [350] |