WP_HEDGEHOG_SIGNALING_PATHWAY_WP47 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SAP18 Histone deacetylase complex subunit SAP18 [1] -0.49[2] -0.49[3] -1.06[4] -0.93[5] -0.82[6] -0.50[7]
2 ARNTL Aryl hydrocarbon receptor nuclear translocator-like protein 1 [8] -2.52[9] -2.21[10] -3.50[11] -1.82[12] -1.36[13] 0.42[14]
3 SIN3A Paired amphipathic helix protein Sin3a [15] 0.93[16] 0.82[17] 1.70[18] 1.21[19] 1.24[20] 0.92[21]
4 SMO Smoothened homolog [22] 0.72[23] 0.90[24] 0.73[25] 0.37[26] -0.07[27] -0.11[28]
5 STK36 Serine/threonine-protein kinase 36 [29] 0.98[30] 1.57[31] 0.23[32] 0.57[33] 1.03[34] 0.87[35]
6 SUFU Suppressor of fused homolog [36] 1.01[37] 0.83[38] 1.45[39] 0.44[40] 1.23[41] 0.00[42]
7 SHH Sonic hedgehog protein [43] -0.07[44] -0.41[45] -0.66[46] -7.96[47] -7.82[48] -0.23[49]
8 KIF7 Kinesin-like protein KIF7 [50] 3.00[51] 1.02[52] 0.85[53] 2.26[54] 2.92[55] -0.09[56]
9 PTCH1 Protein patched homolog 1 [57] 2.19[58] 2.23[59] 3.27[60] 2.55[61] 2.17[62] 2.48[63]
10 IHH Indian hedgehog protein [64] 0.61[65] -1.54[66] 3.95[67] -5.07[68] -5.66[69] -0.27[70]
11 GLI1 Zinc finger protein GLI1 [71] -2.09[72] -2.44[73] 0.46[74] -1.87[75] 1.01[76] 0.60[77]
12 PTCH2 Protein patched homolog 2 [78] 2.79[79] 3.90[80] -0.02[81] -0.26[82] 1.20[83] 1.56[84]
13 GLI2 Zinc finger protein GLI2 [85] 0.20[86] -3.55[87] -2.13[88] 7.69[89] 7.15[90] 2.52[91]
14 GLI3 Transcriptional activator GLI3 [92] -1.67[93] [94] -1.24[95] 8.16[96] 6.80[97] 3.79[98]
15 DHH Desert hedgehog protein [99] [100] [101] [102] [103] [104] [105]
16 GRK2 Beta-adrenergic receptor kinase 1 [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte SAP18
Mean 26.6
Standard deviation 13
Values 30 43 32 13 15
[2]
HepG2 SAP18
Mean 56.8
Standard deviation 5.2
Values 61 53
[3]
HepG2.C3A SAP18
Mean 58.2
Standard deviation 13
Values 67 49
[4]
HuH.7 SAP18
Mean 47.2
Standard deviation 11
Values 59 38 44
[5]
SNU475 SAP18
Mean 43.7
Standard deviation 1.9
Values 45 42
[6]
THLE SAP18
Mean 44
Standard deviation 5.6
Values 40 48
[7]
liver SAP18
Mean 34.4
Standard deviation 31
Values 5.6 9.1 65 58
[8]
ref_hepatocyte ARNTL
Mean 5.32
Standard deviation 2.6
Values 4.6 7.5 7.9 1.3 5.3
[9]
HepG2 ARNTL
Mean 2.79
Standard deviation 0.22
Values 2.9 2.6
[10]
HepG2.C3A ARNTL
Mean 3.53
Standard deviation 0.11
Values 3.5 3.6
[11]
HuH.7 ARNTL
Mean 1.74
Standard deviation 0.12
Values 1.8 1.8 1.6
[12]
SNU475 ARNTL
Mean 4.73
Standard deviation 0.49
Values 5.1 4.4
[13]
THLE ARNTL
Mean 6.03
Standard deviation 0.14
Values 5.9 6.1
[14]
liver ARNTL
Mean 13.1
Standard deviation 2.3
Values 12 12 12 17
[15]
ref_hepatocyte SIN3A
Mean 3.84
Standard deviation 1.6
Values 4.1 2.4 2.3 4.4 6
[16]
HepG2 SIN3A
Mean 22
Standard deviation 0.2
Values 22 22
[17]
HepG2.C3A SIN3A
Mean 20.9
Standard deviation 1.9
Values 20 22
[18]
HuH.7 SIN3A
Mean 46
Standard deviation 6.9
Values 41 44 54
[19]
SNU475 SIN3A
Mean 28
Standard deviation 1.4
Values 29 27
[20]
THLE SIN3A
Mean 26.4
Standard deviation 5.5
Values 23 30
[21]
liver SIN3A
Mean 13.3
Standard deviation 1.8
Values 14 15 13 11
[22]
ref_hepatocyte SMO
Mean 3.57
Standard deviation 2.2
Values 1.1 6 3.9 5.2 1.6
[23]
HepG2 SMO
Mean 17.8
Standard deviation 4.5
Values 21 15
[24]
HepG2.C3A SMO
Mean 20.5
Standard deviation 5.7
Values 16 25
[25]
HuH.7 SMO
Mean 21.9
Standard deviation 2.6
Values 23 19 24
[26]
SNU475 SMO
Mean 14.5
Standard deviation 3.9
Values 12 17
[27]
THLE SMO
Mean 9.89
Standard deviation 1.3
Values 9 11
[28]
liver SMO
Mean 6.03
Standard deviation 3.6
Values 11 5.8 5 2.3
[29]
ref_hepatocyte STK36
Mean 1.67
Standard deviation 1.7
Values 0.68 0.66 0.66 4.6 1.7
[30]
HepG2 STK36
Mean 9.92
Standard deviation 3.9
Values 13 7.2
[31]
HepG2.C3A STK36
Mean 15.2
Standard deviation 2
Values 17 14
[32]
HuH.7 STK36
Mean 7.23
Standard deviation 0.8
Values 8.1 6.5 7.1
[33]
SNU475 STK36
Mean 7.77
Standard deviation 0.61
Values 7.3 8.2
[34]
THLE STK36
Mean 9.93
Standard deviation 1
Values 11 9.2
[35]
liver STK36
Mean 5.55
Standard deviation 0.32
Values 5.1 5.6 5.9 5.5
[36]
ref_hepatocyte SUFU
Mean 1.52
Standard deviation 0.31
Values 2 1.2 1.3 1.7 1.4
[37]
HepG2 SUFU
Mean 9.22
Standard deviation 1.6
Values 8.1 10
[38]
HepG2.C3A SUFU
Mean 8.33
Standard deviation 1.3
Values 7.4 9.3
[39]
HuH.7 SUFU
Mean 15.3
Standard deviation 5.1
Values 14 11 21
[40]
SNU475 SUFU
Mean 6.49
Standard deviation 0.52
Values 6.9 6.1
[41]
THLE SUFU
Mean 10.4
Standard deviation 1.4
Values 9.4 11
[42]
liver SUFU
Mean 2.78
Standard deviation 0.66
Values 2.4 2.2 3.7 2.9
[43]
ref_hepatocyte SHH
Mean 1.15
Standard deviation 1
Values 2.5 1.6 1.4 0.23 0
[44]
HepG2 SHH
Mean 3.31
Standard deviation 2.1
Values 1.8 4.8
[45]
HepG2.C3A SHH
Mean 2.66
Standard deviation 0.92
Values 2 3.3
[46]
HuH.7 SHH
Mean 2.69
Standard deviation 0.5
Values 2.3 3.3 2.5
[47]
SNU475 SHH
Mean 0.0146
Standard deviation 0.00091
Values 0.015 0.014
[48]
THLE SHH
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[49]
liver SHH
Mean 1.79
Standard deviation 2.1
Values 4.1 2.9 0.12 0
[50]
ref_hepatocyte KIF7
Mean 0.285
Standard deviation 0.36
Values 0.079 0.089 0.13 0.92 0.2
[51]
HepG2 KIF7
Mean 6.85
Standard deviation 0.47
Values 7.2 6.5
[52]
HepG2.C3A KIF7
Mean 1.77
Standard deviation 0.47
Values 2.1 1.4
[53]
HuH.7 KIF7
Mean 1.9
Standard deviation 0.52
Values 2.2 1.3 2.2
[54]
SNU475 KIF7
Mean 4.29
Standard deviation 0.022
Values 4.3 4.3
[55]
THLE KIF7
Mean 6.26
Standard deviation 2.3
Values 7.9 4.6
[56]
liver KIF7
Mean 0.488
Standard deviation 0.42
Values 0.85 0.86 0.094 0.15
[57]
ref_hepatocyte PTCH1
Mean 0.253
Standard deviation 0.18
Values 0.51 0.37 0.078 0.17 0.14
[58]
HepG2 PTCH1
Mean 3.48
Standard deviation 2.7
Values 1.6 5.4
[59]
HepG2.C3A PTCH1
Mean 3.66
Standard deviation 0.94
Values 3 4.3
[60]
HuH.7 PTCH1
Mean 9.01
Standard deviation 1
Values 7.9 9 10
[61]
SNU475 PTCH1
Mean 4.67
Standard deviation 0.47
Values 5 4.3
[62]
THLE PTCH1
Mean 3.31
Standard deviation 0.69
Values 2.8 3.8
[63]
liver PTCH1
Mean 2.58
Standard deviation 0.39
Values 2.6 2 2.9 2.8
[64]
ref_hepatocyte IHH
Mean 0.19
Standard deviation 0.27
Values 0 0.62 0.28 0 0.054
[65]
HepG2 IHH
Mean 0.871
Standard deviation 0.39
Values 1.1 0.6
[66]
HepG2.C3A IHH
Mean 0.201
Standard deviation 0.05
Values 0.24 0.17
[67]
HuH.7 IHH
Mean 10.8
Standard deviation 0.98
Values 11 11 9.7
[68]
SNU475 IHH
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[69]
THLE IHH
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[70]
liver IHH
Mean 0.288
Standard deviation 0.17
Values 0.36 0.17 0.49 0.13
[71]
ref_hepatocyte GLI1
Mean 0.113
Standard deviation 0.22
Values 0.5 0.024 0.043 0 0
[72]
HepG2 GLI1
Mean 0.0802
Standard deviation 0.041
Values 0.051 0.11
[73]
HepG2.C3A GLI1
Mean 0.0642
Standard deviation 0.06
Values 0.021 0.11
[74]
HuH.7 GLI1
Mean 0.579
Standard deviation 0.11
Values 0.45 0.65 0.63
[75]
SNU475 GLI1
Mean 0.0979
Standard deviation 0.034
Values 0.12 0.074
[76]
THLE GLI1
Mean 0.667
Standard deviation 0.23
Values 0.83 0.51
[77]
liver GLI1
Mean 0.315
Standard deviation 0.33
Values 0.38 0.071 0.75 0.051
[78]
ref_hepatocyte PTCH2
Mean 0.0404
Standard deviation 0.056
Values 0 0.024 0.043 0 0.13
[79]
HepG2 PTCH2
Mean 0.839
Standard deviation 0.48
Values 0.5 1.2
[80]
HepG2.C3A PTCH2
Mean 1.86
Standard deviation 1
Values 1.1 2.6
[81]
HuH.7 PTCH2
Mean 0.148
Standard deviation 0.03
Values 0.12 0.14 0.18
[82]
SNU475 PTCH2
Mean 0.106
Standard deviation 0.065
Values 0.15 0.06
[83]
THLE PTCH2
Mean 0.27
Standard deviation 0.1
Values 0.34 0.2
[84]
liver PTCH2
Mean 0.218
Standard deviation 0.1
Values 0.23 0.086 0.33 0.23
[85]
ref_hepatocyte GLI2
Mean 0.0185
Standard deviation 0.037
Values 0.084 0.0081 0 0 0
[86]
HepG2 GLI2
Mean 0.0637
Standard deviation 0.023
Values 0.047 0.08
[87]
HepG2.C3A GLI2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[88]
HuH.7 GLI2
Mean 0.0156
Standard deviation 0.02
Values 0 0.039 0.0082
[89]
SNU475 GLI2
Mean 12
Standard deviation 1.6
Values 11 13
[90]
THLE GLI2
Mean 7.63
Standard deviation 1.7
Values 6.4 8.8
[91]
liver GLI2
Mean 0.194
Standard deviation 0.054
Values 0.25 0.23 0.14 0.15
[92]
ref_hepatocyte GLI3
Mean 0.0152
Standard deviation 0.021
Values 0.043 0.033 0 0 0
[93]
HepG2 GLI3
Mean 0.0143
Standard deviation 0.02
Values 0 0.029
[94]
HepG2.C3A GLI3
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 GLI3
Mean 0.0238
Standard deviation 0.021
Values 0 0.039 0.033
[96]
SNU475 GLI3
Mean 13.7
Standard deviation 1.2
Values 13 14
[97]
THLE GLI3
Mean 4.94
Standard deviation 1.2
Values 4.1 5.8
[98]
liver GLI3
Mean 0.384
Standard deviation 0.18
Values 0.42 0.37 0.59 0.15
[99]
ref_hepatocyte DHH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 DHH
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[101]
HepG2.C3A DHH
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[102]
HuH.7 DHH
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[103]
SNU475 DHH
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[104]
THLE DHH
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[105]
liver DHH
Mean 0.03
Standard deviation 0.051
Values 0.11 0.014 0 0
[106]
ref_hepatocyte GRK2
Missing
[107]
HepG2 GRK2
Missing
[108]
HepG2.C3A GRK2
Missing
[109]
HuH.7 GRK2
Missing
[110]
SNU475 GRK2
Missing
[111]
THLE GRK2
Missing
[112]
liver GRK2
Missing