WP_HEDGEHOG_SIGNALING_PATHWAY_WP4249 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CCND1 G1/S-specific cyclin-D1 [1] 1.54[2] -0.33[3] 0.30[4] 0.66[5] -0.55[6] 0.42[7]
2 CSNK1A1 Casein kinase I isoform alpha [8] -1.18[9] -0.55[10] -0.98[11] -0.38[12] -0.02[13] 0.05[14]
3 CSNK1D Casein kinase I isoform delta [15] -0.34[16] 0.06[17] -0.23[18] -0.19[19] -0.39[20] -1.23[21]
4 PRKACA cAMP-dependent protein kinase catalytic subunit alpha [22] -1.68[23] -1.22[24] -1.42[25] -1.68[26] -0.83[27] -1.42[28]
5 SPOP Speckle-type POZ protein [29] -1.32[30] -0.10[31] -0.61[32] -0.88[33] -0.57[34] 0.13[35]
6 ARRB2 Beta-arrestin-2 [36] -1.35[37] -0.33[38] -0.58[39] -2.53[40] -1.46[41] -1.51[42]
7 CSNK1G2 Casein kinase I isoform gamma-2 [43] -0.13[44] 0.47[45] 0.18[46] -1.21[47] -0.23[48] -1.48[49]
8 CSNK1E Casein kinase I isoform epsilon [50] -0.15[51] 0.12[52] 0.57[53] -0.75[54] 0.59[55] -1.46[56]
9 CUL3 Cullin-3 [57] -0.90[58] 0.65[59] 0.16[60] 0.25[61] 0.60[62] 0.30[63]
10 SPOPL Speckle-type POZ protein-like [64] -0.97[65] 0.71[66] 0.41[67] -0.27[68] -0.62[69] 0.24[70]
11 CSNK1G3 Casein kinase I isoform gamma-3 [71] -1.70[72] 0.38[73] -0.34[74] 0.05[75] 0.13[76] 0.66[77]
12 SMO Smoothened homolog [78] -0.35[79] 0.67[80] 0.62[81] -0.07[82] -0.52[83] -0.39[84]
13 SMURF1 E3 ubiquitin-protein ligase SMURF1 [85] -0.08[86] 0.01[87] 0.71[88] 0.00[89] 0.15[90] 0.75[91]
14 PRKACB cAMP-dependent protein kinase catalytic subunit beta [92] -2.35[93] -0.94[94] 0.14[95] 1.02[96] 0.14[97] 1.07[98]
15 SMURF2 E3 ubiquitin-protein ligase SMURF2 [99] 0.20[100] 0.86[101] -0.83[102] -0.02[103] 0.69[104] -0.50[105]
16 FBXL17 F-box/LRR-repeat protein 17 [106] -1.45[107] -0.01[108] -3.37[109] 0.34[110] 0.03[111] 0.83[112]
17 SUFU Suppressor of fused homolog [113] -0.06[114] 0.60[115] 1.33[116] 0.00[117] 0.79[118] -0.27[119]
18 CSNK1G1 Casein kinase I isoform gamma-1 [120] 0.31[121] 1.17[122] 1.39[123] 1.23[124] 1.41[125] 1.03[126]
19 KIF3A Kinesin-like protein KIF3A [127] -0.87[128] 0.80[129] -0.49[130] 0.91[131] 0.91[132] -0.26[133]
20 SHH Sonic hedgehog protein [134] -1.14[135] -0.65[136] -0.77[137] -8.40[138] -8.27[139] -0.51[140]
21 CCND2 G1/S-specific cyclin-D2 [141] 1.63[142] 0.85[143] -5.57[144] -5.66[145] -2.49[146] 1.22[147]
22 ARRB1 Beta-arrestin-1 [148] 2.07[149] 2.51[150] 1.60[151] 0.94[152] 1.01[153] 2.63[154]
23 CDON Cell adhesion molecule-related/down-regulated by oncogenes [155] 1.58[156] 1.67[157] 1.28[158] 3.05[159] 1.71[160] 1.65[161]
24 EVC Ellis-van Creveld syndrome protein [162] 1.13[163] -1.20[164] -5.40[165] 3.26[166] 4.06[167] 1.91[168]
25 KIF7 Kinesin-like protein KIF7 [169] 1.93[170] 0.78[171] 0.74[172] 1.82[173] 2.47[174] -0.37[175]
26 PTCH1 Protein patched homolog 1 [176] 1.12[177] 2.00[178] 3.15[179] 2.11[180] 1.72[181] 2.20[182]
27 IHH Indian hedgehog protein [183] -0.46[184] -1.77[185] 3.83[186] -5.51[187] -6.11[188] -0.54[189]
28 GLI1 Zinc finger protein GLI1 [190] -3.16[191] -2.68[192] 0.35[193] -2.31[194] 0.56[195] 0.33[196]
29 BCL2 Apoptosis regulator Bcl-2 [197] -4.37[198] 1.67[199] -5.94[200] 0.56[201] 0.54[202] 2.59[203]
30 GAS1 Growth arrest-specific protein 1 [204] -6.12[205] [206] -5.20[207] -0.24[208] 5.07[209] 1.53[210]
31 LRP2 Low-density lipoprotein receptor-related protein 2 [211] 0.79[212] -1.91[213] 6.57[214] -3.49[215] -3.49[216] 5.58[217]
32 GPR161 G-protein coupled receptor 161 [218] 2.11[219] 0.18[220] 2.30[221] 4.81[222] 4.21[223] 3.30[224]
33 PTCH2 Protein patched homolog 2 [225] 1.72[226] 3.67[227] -0.13[228] -0.70[229] 0.75[230] 1.28[231]
34 GLI2 Zinc finger protein GLI2 [232] -0.87[233] -3.78[234] -2.25[235] 7.25[236] 6.70[237] 2.25[238]
35 GLI3 Transcriptional activator GLI3 [239] -2.74[240] [241] -1.35[242] 7.72[243] 6.35[244] 3.51[245]
36 EVC2 Limbin [246] -4.47[247] -2.76[248] -3.69[249] 3.27[250] 6.98[251] 5.09[252]
37 BOC Brother of CDO [253] 0.01[254] [255] -1.50[256] 6.55[257] 4.60[258] 3.91[259]
38 DHH Desert hedgehog protein [260] [261] [262] [263] [264] [265] [266]
39 HHIP Hedgehog-interacting protein [267] [268] [269] [270] [271] [272] [273]
40 PRKACG cAMP-dependent protein kinase catalytic subunit gamma [274] [275] [276] [277] [278] [279] [280]
41 CSNK1A1L Casein kinase I isoform alpha-like [281] [282] [283] [284] [285] [286] [287]
42 GRK3 Beta-adrenergic receptor kinase 2 [288] [289] [290] [291] [292] [293] [294]
43 GRK2 Beta-adrenergic receptor kinase 1 [295] [296] [297] [298] [299] [300] [301]
44 TPTEP2-CSNK1E [302] [303] [304] [305] [306] [307] [308]
[1]
ref_hepatocyte CCND1
Mean 23
Standard deviation 14
Values 19 12 11 44 28
[2]
HepG2 CCND1
Mean 421
Standard deviation 48
Values 3.9e+02 4.5e+02
[3]
HepG2.C3A CCND1
Mean 66.1
Standard deviation 12
Values 74 58
[4]
HuH.7 CCND1
Mean 113
Standard deviation 31
Values 1.2e+02 79 1.4e+02
[5]
SNU475 CCND1
Mean 155
Standard deviation 66
Values 2e+02 1.1e+02
[6]
THLE CCND1
Mean 62.5
Standard deviation 6.4
Values 67 58
[7]
liver CCND1
Mean 67.8
Standard deviation 49
Values 25 1.1e+02 26 1.1e+02
[8]
ref_hepatocyte CSNK1A1
Mean 20.7
Standard deviation 9.8
Values 35 14 10 20 24
[9]
HepG2 CSNK1A1
Mean 57.9
Standard deviation 0.1
Values 58 58
[10]
HepG2.C3A CSNK1A1
Mean 51.1
Standard deviation 2
Values 53 50
[11]
HuH.7 CSNK1A1
Mean 41.8
Standard deviation 2.9
Values 41 39 45
[12]
SNU475 CSNK1A1
Mean 67.7
Standard deviation 7.6
Values 62 73
[13]
THLE CSNK1A1
Mean 81.2
Standard deviation 5.1
Values 78 85
[14]
liver CSNK1A1
Mean 47.5
Standard deviation 6.3
Values 47 56 41 47
[15]
ref_hepatocyte CSNK1D
Mean 18
Standard deviation 10
Values 14 6.5 13 31 25
[16]
HepG2 CSNK1D
Mean 89.7
Standard deviation 12
Values 81 98
[17]
HepG2.C3A CSNK1D
Mean 67.9
Standard deviation 18
Values 55 81
[18]
HuH.7 CSNK1D
Mean 61.3
Standard deviation 2.1
Values 64 60 60
[19]
SNU475 CSNK1D
Mean 67.2
Standard deviation 23
Values 51 84
[20]
THLE CSNK1D
Mean 54.7
Standard deviation 1
Values 54 55
[21]
liver CSNK1D
Mean 17
Standard deviation 6.7
Values 13 10 24 21
[22]
ref_hepatocyte PRKACA
Mean 15.8
Standard deviation 8.3
Values 11 23 27 7.6 11
[23]
HepG2 PRKACA
Mean 31.2
Standard deviation 2.7
Values 33 29
[24]
HepG2.C3A PRKACA
Mean 24.6
Standard deviation 3.5
Values 22 27
[25]
HuH.7 PRKACA
Mean 23.6
Standard deviation 5.7
Values 27 17 27
[26]
SNU475 PRKACA
Mean 21
Standard deviation 3.3
Values 19 23
[27]
THLE PRKACA
Mean 35.4
Standard deviation 5.3
Values 32 39
[28]
liver PRKACA
Mean 13.1
Standard deviation 4.9
Values 8.9 8.8 18 16
[29]
ref_hepatocyte SPOP
Mean 8.84
Standard deviation 2.6
Values 5.2 11 12 8.2 8.1
[30]
HepG2 SPOP
Mean 22.4
Standard deviation 3.5
Values 25 20
[31]
HepG2.C3A SPOP
Mean 29.9
Standard deviation 2.1
Values 28 31
[32]
HuH.7 SPOP
Mean 23.1
Standard deviation 0.29
Values 23 23 23
[33]
SNU475 SPOP
Mean 20.5
Standard deviation 2
Values 19 22
[34]
THLE SPOP
Mean 23.6
Standard deviation 4.9
Values 20 27
[35]
liver SPOP
Mean 21.4
Standard deviation 8.1
Values 14 15 30 27
[36]
ref_hepatocyte ARRB2
Mean 7.58
Standard deviation 4.1
Values 3.6 7.8 8.2 14 4.4
[37]
HepG2 ARRB2
Mean 18.8
Standard deviation 5.4
Values 15 23
[38]
HepG2.C3A ARRB2
Mean 21.9
Standard deviation 3.9
Values 19 25
[39]
HuH.7 ARRB2
Mean 20.3
Standard deviation 3.2
Values 23 17 20
[40]
SNU475 ARRB2
Mean 5.59
Standard deviation 0.33
Values 5.8 5.4
[41]
THLE ARRB2
Mean 10.9
Standard deviation 0.23
Values 11 11
[42]
liver ARRB2
Mean 5.88
Standard deviation 3.8
Values 2.6 2.5 9.3 9.1
[43]
ref_hepatocyte CSNK1G2
Mean 7.57
Standard deviation 4.9
Values 16 4.7 7.6 3.2 6.6
[44]
HepG2 CSNK1G2
Mean 43.8
Standard deviation 9.5
Values 37 51
[45]
HepG2.C3A CSNK1G2
Mean 37.9
Standard deviation 5.4
Values 34 42
[46]
HuH.7 CSNK1G2
Mean 34.4
Standard deviation 3.9
Values 37 30 36
[47]
SNU475 CSNK1G2
Mean 14
Standard deviation 1.1
Values 13 15
[48]
THLE CSNK1G2
Mean 25.6
Standard deviation 1.1
Values 25 26
[49]
liver CSNK1G2
Mean 6.02
Standard deviation 2.9
Values 9.1 7.8 3.9 3.2
[50]
ref_hepatocyte CSNK1E
Mean 6.27
Standard deviation 5.9
Values 16 1.4 1.9 6.5 5.5
[51]
HepG2 CSNK1E
Mean 35.7
Standard deviation 14
Values 26 45
[52]
HepG2.C3A CSNK1E
Mean 24.6
Standard deviation 8.9
Values 18 31
[53]
HuH.7 CSNK1E
Mean 37.3
Standard deviation 3.1
Values 40 37 34
[54]
SNU475 CSNK1E
Mean 15.9
Standard deviation 1.1
Values 15 17
[55]
THLE CSNK1E
Mean 37.4
Standard deviation 4.6
Values 34 41
[56]
liver CSNK1E
Mean 5.04
Standard deviation 1.3
Values 6.1 4.4 6 3.6
[57]
ref_hepatocyte CUL3
Mean 5.91
Standard deviation 1.6
Values 3.5 6 5.4 7.2 7.4
[58]
HepG2 CUL3
Mean 20
Standard deviation 5.9
Values 24 16
[59]
HepG2.C3A CUL3
Mean 33.5
Standard deviation 2.3
Values 35 32
[60]
HuH.7 CUL3
Mean 26.4
Standard deviation 3
Values 27 23 29
[61]
SNU475 CUL3
Mean 29.9
Standard deviation 0.9
Values 31 29
[62]
THLE CUL3
Mean 35.6
Standard deviation 0.55
Values 35 36
[63]
liver CUL3
Mean 16.1
Standard deviation 5.2
Values 20 20 15 9.1
[64]
ref_hepatocyte SPOPL
Mean 4.2
Standard deviation 5
Values 1.3 1.8 1.2 13 3.7
[65]
HepG2 SPOPL
Mean 13.5
Standard deviation 6.4
Values 18 9
[66]
HepG2.C3A SPOPL
Mean 24.8
Standard deviation 7.3
Values 30 20
[67]
HuH.7 SPOPL
Mean 22.3
Standard deviation 4.6
Values 17 26 24
[68]
SNU475 SPOPL
Mean 14.8
Standard deviation 3.8
Values 12 17
[69]
THLE SPOPL
Mean 10.8
Standard deviation 0.035
Values 11 11
[70]
liver SPOPL
Mean 10.9
Standard deviation 3.6
Values 14 13 9.8 6.4
[71]
ref_hepatocyte CSNK1G3
Mean 3.73
Standard deviation 1.5
Values 5.1 2.2 2.2 4.1 5.2
[72]
HepG2 CSNK1G3
Mean 7.26
Standard deviation 0.88
Values 7.9 6.6
[73]
HepG2.C3A CSNK1G3
Mean 17.6
Standard deviation 2.1
Values 16 19
[74]
HuH.7 CSNK1G3
Mean 11.8
Standard deviation 0.54
Values 12 11 12
[75]
SNU475 CSNK1G3
Mean 16.5
Standard deviation 0.0066
Values 17 17
[76]
THLE CSNK1G3
Mean 16.2
Standard deviation 1.9
Values 18 15
[77]
liver CSNK1G3
Mean 13.1
Standard deviation 1.9
Values 13 15 14 11
[78]
ref_hepatocyte SMO
Mean 3.57
Standard deviation 2.2
Values 1.1 6 3.9 5.2 1.6
[79]
HepG2 SMO
Mean 17.8
Standard deviation 4.5
Values 21 15
[80]
HepG2.C3A SMO
Mean 20.5
Standard deviation 5.7
Values 16 25
[81]
HuH.7 SMO
Mean 21.9
Standard deviation 2.6
Values 23 19 24
[82]
SNU475 SMO
Mean 14.5
Standard deviation 3.9
Values 12 17
[83]
THLE SMO
Mean 9.89
Standard deviation 1.3
Values 9 11
[84]
liver SMO
Mean 6.03
Standard deviation 3.6
Values 11 5.8 5 2.3
[85]
ref_hepatocyte SMURF1
Mean 3.55
Standard deviation 2.6
Values 7.2 0.92 1.5 3 5.1
[86]
HepG2 SMURF1
Mean 21.3
Standard deviation 3.9
Values 19 24
[87]
HepG2.C3A SMURF1
Mean 12.9
Standard deviation 1.5
Values 12 14
[88]
HuH.7 SMURF1
Mean 23.3
Standard deviation 5.2
Values 18 29 23
[89]
SNU475 SMURF1
Mean 15.1
Standard deviation 1.3
Values 16 14
[90]
THLE SMURF1
Mean 15.7
Standard deviation 2.1
Values 14 17
[91]
liver SMURF1
Mean 13.2
Standard deviation 6
Values 19 18 7.3 8.8
[92]
ref_hepatocyte PRKACB
Mean 2.75
Standard deviation 1.3
Values 1.4 4.8 2.4 2.1 3.1
[93]
HepG2 PRKACB
Mean 3.41
Standard deviation 1.6
Values 4.6 2.3
[94]
HepG2.C3A PRKACB
Mean 5.2
Standard deviation 0.9
Values 5.8 4.6
[95]
HuH.7 PRKACB
Mean 12.2
Standard deviation 3.4
Values 9.5 16 11
[96]
SNU475 PRKACB
Mean 23.8
Standard deviation 4.4
Values 21 27
[97]
THLE PRKACB
Mean 12.1
Standard deviation 0.96
Values 13 11
[98]
liver PRKACB
Mean 12.8
Standard deviation 2
Values 10 14 12 14
[99]
ref_hepatocyte SMURF2
Mean 2.04
Standard deviation 1.5
Values 2.7 0.48 0.61 4 2.4
[100]
HepG2 SMURF2
Mean 14.8
Standard deviation 1.9
Values 16 13
[101]
HepG2.C3A SMURF2
Mean 13.4
Standard deviation 0.28
Values 14 13
[102]
HuH.7 SMURF2
Mean 4.58
Standard deviation 0.75
Values 4 5.4 4.3
[103]
SNU475 SMURF2
Mean 8.55
Standard deviation 1
Values 9.3 7.8
[104]
THLE SMURF2
Mean 13
Standard deviation 1.5
Values 12 14
[105]
liver SMURF2
Mean 3.18
Standard deviation 1.7
Values 4 5.1 1.8 1.8
[106]
ref_hepatocyte FBXL17
Mean 1.56
Standard deviation 0.94
Values 0.93 2.9 0.72 2.2 1
[107]
HepG2 FBXL17
Mean 3.61
Standard deviation 1.2
Values 4.5 2.8
[108]
HepG2.C3A FBXL17
Mean 5.58
Standard deviation 0.23
Values 5.7 5.4
[109]
HuH.7 FBXL17
Mean 0.603
Standard deviation 0.2
Values 0.66 0.78 0.38
[110]
SNU475 FBXL17
Mean 8.39
Standard deviation 3.6
Values 5.9 11
[111]
THLE FBXL17
Mean 6.33
Standard deviation 1.6
Values 5.2 7.5
[112]
liver FBXL17
Mean 6.14
Standard deviation 4.7
Values 12 8.6 2.4 2
[113]
ref_hepatocyte SUFU
Mean 1.52
Standard deviation 0.31
Values 2 1.2 1.3 1.7 1.4
[114]
HepG2 SUFU
Mean 9.22
Standard deviation 1.6
Values 8.1 10
[115]
HepG2.C3A SUFU
Mean 8.33
Standard deviation 1.3
Values 7.4 9.3
[116]
HuH.7 SUFU
Mean 15.3
Standard deviation 5.1
Values 14 11 21
[117]
SNU475 SUFU
Mean 6.49
Standard deviation 0.52
Values 6.9 6.1
[118]
THLE SUFU
Mean 10.4
Standard deviation 1.4
Values 9.4 11
[119]
liver SUFU
Mean 2.78
Standard deviation 0.66
Values 2.4 2.2 3.7 2.9
[120]
ref_hepatocyte CSNK1G1
Mean 1.48
Standard deviation 1.4
Values 1.7 0.33 0.31 3.7 1.3
[121]
HepG2 CSNK1G1
Mean 11.6
Standard deviation 2.5
Values 13 9.8
[122]
HepG2.C3A CSNK1G1
Mean 12
Standard deviation 0.84
Values 13 11
[123]
HuH.7 CSNK1G1
Mean 15.5
Standard deviation 5
Values 10 21 15
[124]
SNU475 CSNK1G1
Mean 14.8
Standard deviation 1.3
Values 14 16
[125]
THLE CSNK1G1
Mean 15.6
Standard deviation 1.6
Values 14 17
[126]
liver CSNK1G1
Mean 6.68
Standard deviation 1.4
Values 7.3 8.3 5.9 5.2
[127]
ref_hepatocyte KIF3A
Mean 1.18
Standard deviation 1.1
Values 0.74 0.24 0.33 2.7 1.9
[128]
HepG2 KIF3A
Mean 4.09
Standard deviation 0.63
Values 4.5 3.6
[129]
HepG2.C3A KIF3A
Mean 7.45
Standard deviation 0.61
Values 7 7.9
[130]
HuH.7 KIF3A
Mean 3.38
Standard deviation 0.57
Values 3.1 3 4
[131]
SNU475 KIF3A
Mean 9.52
Standard deviation 1.3
Values 8.6 10
[132]
THLE KIF3A
Mean 8.85
Standard deviation 1.2
Values 9.7 8
[133]
liver KIF3A
Mean 2.19
Standard deviation 0.84
Values 1.4 2.7 1.5 3.1
[134]
ref_hepatocyte SHH
Mean 1.15
Standard deviation 1
Values 2.5 1.6 1.4 0.23 0
[135]
HepG2 SHH
Mean 3.31
Standard deviation 2.1
Values 1.8 4.8
[136]
HepG2.C3A SHH
Mean 2.66
Standard deviation 0.92
Values 2 3.3
[137]
HuH.7 SHH
Mean 2.69
Standard deviation 0.5
Values 2.3 3.3 2.5
[138]
SNU475 SHH
Mean 0.0146
Standard deviation 0.00091
Values 0.015 0.014
[139]
THLE SHH
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[140]
liver SHH
Mean 1.79
Standard deviation 2.1
Values 4.1 2.9 0.12 0
[141]
ref_hepatocyte CCND2
Mean 0.667
Standard deviation 0.74
Values 0.095 1.9 0.79 0.071 0.5
[142]
HepG2 CCND2
Mean 13
Standard deviation 3.2
Values 15 11
[143]
HepG2.C3A CCND2
Mean 4.34
Standard deviation 2.4
Values 2.6 6.1
[144]
HuH.7 CCND2
Mean 0.0563
Standard deviation 0.028
Values 0.028 0.083 0.057
[145]
SNU475 CCND2
Mean 0.0561
Standard deviation 0.014
Values 0.066 0.046
[146]
THLE CCND2
Mean 0.473
Standard deviation 0.28
Values 0.67 0.28
[147]
liver CCND2
Mean 3.43
Standard deviation 1
Values 4.2 2.9 4.4 2.2
[148]
ref_hepatocyte ARRB1
Mean 0.644
Standard deviation 0.19
Values 0.92 0.41 0.69 0.65 0.54
[149]
HepG2 ARRB1
Mean 17.1
Standard deviation 1.4
Values 16 18
[150]
HepG2.C3A ARRB1
Mean 13.3
Standard deviation 2.1
Values 12 15
[151]
HuH.7 ARRB1
Mean 7.82
Standard deviation 0.6
Values 7.3 8.4 7.8
[152]
SNU475 ARRB1
Mean 5.26
Standard deviation 0.39
Values 5 5.5
[153]
THLE ARRB1
Mean 5.15
Standard deviation 0.95
Values 4.5 5.8
[154]
liver ARRB1
Mean 8.83
Standard deviation 5.7
Values 16 11 5 3.6
[155]
ref_hepatocyte CDON
Mean 0.452
Standard deviation 0.47
Values 0.36 0.19 0.16 1.3 0.26
[156]
HepG2 CDON
Mean 8.54
Standard deviation 0.057
Values 8.6 8.5
[157]
HepG2.C3A CDON
Mean 5.21
Standard deviation 0.24
Values 5 5.4
[158]
HuH.7 CDON
Mean 4.38
Standard deviation 1.8
Values 2.8 6.4 4
[159]
SNU475 CDON
Mean 16
Standard deviation 6.6
Values 11 21
[160]
THLE CDON
Mean 5.88
Standard deviation 0.097
Values 5.8 6
[161]
liver CDON
Mean 3.14
Standard deviation 2.4
Values 6.5 3.4 1.6 1.1
[162]
ref_hepatocyte EVC
Mean 0.392
Standard deviation 0.37
Values 0.24 0.16 0.086 1 0.47
[163]
HepG2 EVC
Mean 5.41
Standard deviation 1.7
Values 6.6 4.2
[164]
HepG2.C3A EVC
Mean 0.619
Standard deviation 0.05
Values 0.65 0.58
[165]
HuH.7 EVC
Mean 0.037
Standard deviation 0.02
Values 0.056 0.039 0.016
[166]
SNU475 EVC
Mean 16
Standard deviation 7.3
Values 11 21
[167]
THLE EVC
Mean 26
Standard deviation 10
Values 19 33
[168]
liver EVC
Mean 3.27
Standard deviation 1.9
Values 4.1 5.6 2 1.4
[169]
ref_hepatocyte KIF7
Mean 0.285
Standard deviation 0.36
Values 0.079 0.089 0.13 0.92 0.2
[170]
HepG2 KIF7
Mean 6.85
Standard deviation 0.47
Values 7.2 6.5
[171]
HepG2.C3A KIF7
Mean 1.77
Standard deviation 0.47
Values 2.1 1.4
[172]
HuH.7 KIF7
Mean 1.9
Standard deviation 0.52
Values 2.2 1.3 2.2
[173]
SNU475 KIF7
Mean 4.29
Standard deviation 0.022
Values 4.3 4.3
[174]
THLE KIF7
Mean 6.26
Standard deviation 2.3
Values 7.9 4.6
[175]
liver KIF7
Mean 0.488
Standard deviation 0.42
Values 0.85 0.86 0.094 0.15
[176]
ref_hepatocyte PTCH1
Mean 0.253
Standard deviation 0.18
Values 0.51 0.37 0.078 0.17 0.14
[177]
HepG2 PTCH1
Mean 3.48
Standard deviation 2.7
Values 1.6 5.4
[178]
HepG2.C3A PTCH1
Mean 3.66
Standard deviation 0.94
Values 3 4.3
[179]
HuH.7 PTCH1
Mean 9.01
Standard deviation 1
Values 7.9 9 10
[180]
SNU475 PTCH1
Mean 4.67
Standard deviation 0.47
Values 5 4.3
[181]
THLE PTCH1
Mean 3.31
Standard deviation 0.69
Values 2.8 3.8
[182]
liver PTCH1
Mean 2.58
Standard deviation 0.39
Values 2.6 2 2.9 2.8
[183]
ref_hepatocyte IHH
Mean 0.19
Standard deviation 0.27
Values 0 0.62 0.28 0 0.054
[184]
HepG2 IHH
Mean 0.871
Standard deviation 0.39
Values 1.1 0.6
[185]
HepG2.C3A IHH
Mean 0.201
Standard deviation 0.05
Values 0.24 0.17
[186]
HuH.7 IHH
Mean 10.8
Standard deviation 0.98
Values 11 11 9.7
[187]
SNU475 IHH
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[188]
THLE IHH
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[189]
liver IHH
Mean 0.288
Standard deviation 0.17
Values 0.36 0.17 0.49 0.13
[190]
ref_hepatocyte GLI1
Mean 0.113
Standard deviation 0.22
Values 0.5 0.024 0.043 0 0
[191]
HepG2 GLI1
Mean 0.0802
Standard deviation 0.041
Values 0.051 0.11
[192]
HepG2.C3A GLI1
Mean 0.0642
Standard deviation 0.06
Values 0.021 0.11
[193]
HuH.7 GLI1
Mean 0.579
Standard deviation 0.11
Values 0.45 0.65 0.63
[194]
SNU475 GLI1
Mean 0.0979
Standard deviation 0.034
Values 0.12 0.074
[195]
THLE GLI1
Mean 0.667
Standard deviation 0.23
Values 0.83 0.51
[196]
liver GLI1
Mean 0.315
Standard deviation 0.33
Values 0.38 0.071 0.75 0.051
[197]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.15 0.2 0.12 0.019 0
[198]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.026 0.034
[199]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 0.99 1.3
[200]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[201]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.68 0.55
[202]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[203]
liver BCL2
Mean 1.31
Standard deviation 1
Values 2.5 1.8 0.49 0.49
[204]
ref_hepatocyte GAS1
Mean 0.0949
Standard deviation 0.1
Values 0.13 0.25 0.095 0 0
[205]
HepG2 GAS1
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[206]
HepG2.C3A GAS1
Mean 0
Standard deviation 0
Values 0 0
[207]
HuH.7 GAS1
Mean 0.0103
Standard deviation 0.013
Values 0 0.0064 0.025
[208]
SNU475 GAS1
Mean 0.343
Standard deviation 0.21
Values 0.49 0.19
[209]
THLE GAS1
Mean 12.6
Standard deviation 3.4
Values 10 15
[210]
liver GAS1
Mean 0.608
Standard deviation 0.22
Values 0.66 0.83 0.63 0.31
[211]
ref_hepatocyte LRP2
Mean 0.0646
Standard deviation 0.098
Values 0 0.22 0.1 0 0
[212]
HepG2 LRP2
Mean 0.706
Standard deviation 0.72
Values 0.2 1.2
[213]
HepG2.C3A LRP2
Mean 0.0623
Standard deviation 0.033
Values 0.086 0.039
[214]
HuH.7 LRP2
Mean 24.6
Standard deviation 11
Values 16 21 37
[215]
SNU475 LRP2
Mean 0.0245
Standard deviation 0.0084
Values 0.03 0.019
[216]
THLE LRP2
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[217]
liver LRP2
Mean 6.84
Standard deviation 6.2
Values 13 12 1.3 1.6
[218]
ref_hepatocyte GPR161
Mean 0.0598
Standard deviation 0.065
Values 0.13 0.12 0 0 0.044
[219]
HepG2 GPR161
Mean 1.63
Standard deviation 0.033
Values 1.7 1.6
[220]
HepG2.C3A GPR161
Mean 0.245
Standard deviation 0.0026
Values 0.25 0.24
[221]
HuH.7 GPR161
Mean 1.18
Standard deviation 0.33
Values 1.3 0.8 1.4
[222]
SNU475 GPR161
Mean 7.16
Standard deviation 0.92
Values 6.5 7.8
[223]
THLE GPR161
Mean 4.39
Standard deviation 0.13
Values 4.3 4.5
[224]
liver GPR161
Mean 1.31
Standard deviation 1.1
Values 3 1.1 0.66 0.51
[225]
ref_hepatocyte PTCH2
Mean 0.0404
Standard deviation 0.056
Values 0 0.024 0.043 0 0.13
[226]
HepG2 PTCH2
Mean 0.839
Standard deviation 0.48
Values 0.5 1.2
[227]
HepG2.C3A PTCH2
Mean 1.86
Standard deviation 1
Values 1.1 2.6
[228]
HuH.7 PTCH2
Mean 0.148
Standard deviation 0.03
Values 0.12 0.14 0.18
[229]
SNU475 PTCH2
Mean 0.106
Standard deviation 0.065
Values 0.15 0.06
[230]
THLE PTCH2
Mean 0.27
Standard deviation 0.1
Values 0.34 0.2
[231]
liver PTCH2
Mean 0.218
Standard deviation 0.1
Values 0.23 0.086 0.33 0.23
[232]
ref_hepatocyte GLI2
Mean 0.0185
Standard deviation 0.037
Values 0.084 0.0081 0 0 0
[233]
HepG2 GLI2
Mean 0.0637
Standard deviation 0.023
Values 0.047 0.08
[234]
HepG2.C3A GLI2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[235]
HuH.7 GLI2
Mean 0.0156
Standard deviation 0.02
Values 0 0.039 0.0082
[236]
SNU475 GLI2
Mean 12
Standard deviation 1.6
Values 11 13
[237]
THLE GLI2
Mean 7.63
Standard deviation 1.7
Values 6.4 8.8
[238]
liver GLI2
Mean 0.194
Standard deviation 0.054
Values 0.25 0.23 0.14 0.15
[239]
ref_hepatocyte GLI3
Mean 0.0152
Standard deviation 0.021
Values 0.043 0.033 0 0 0
[240]
HepG2 GLI3
Mean 0.0143
Standard deviation 0.02
Values 0 0.029
[241]
HepG2.C3A GLI3
Mean 0
Standard deviation 0
Values 0 0
[242]
HuH.7 GLI3
Mean 0.0238
Standard deviation 0.021
Values 0 0.039 0.033
[243]
SNU475 GLI3
Mean 13.7
Standard deviation 1.2
Values 13 14
[244]
THLE GLI3
Mean 4.94
Standard deviation 1.2
Values 4.1 5.8
[245]
liver GLI3
Mean 0.384
Standard deviation 0.18
Values 0.42 0.37 0.59 0.15
[246]
ref_hepatocyte EVC2
Mean 0.0101
Standard deviation 0.014
Values 0 0.024 0 0 0.026
[247]
HepG2 EVC2
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[248]
HepG2.C3A EVC2
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[249]
HuH.7 EVC2
Mean 0.00312
Standard deviation 0.0054
Values 0.0094 0 0
[250]
SNU475 EVC2
Mean 0.413
Standard deviation 0.2
Values 0.56 0.27
[251]
THLE EVC2
Mean 5.05
Standard deviation 0.92
Values 4.4 5.7
[252]
liver EVC2
Mean 0.759
Standard deviation 0.45
Values 0.95 1.3 0.54 0.26
[253]
ref_hepatocyte BOC
Mean 0.00813
Standard deviation 0.018
Values 0 0.041 0 0 0
[254]
HepG2 BOC
Mean 0.0516
Standard deviation 0.049
Values 0.017 0.086
[255]
HepG2.C3A BOC
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 BOC
Mean 0.0115
Standard deviation 0.015
Values 0.028 0.0064 0
[257]
SNU475 BOC
Mean 3.24
Standard deviation 0.38
Values 3 3.5
[258]
THLE BOC
Mean 0.781
Standard deviation 0.13
Values 0.88 0.69
[259]
liver BOC
Mean 0.271
Standard deviation 0.4
Values 0.86 0.071 0.024 0.13
[260]
ref_hepatocyte DHH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[261]
HepG2 DHH
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[262]
HepG2.C3A DHH
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[263]
HuH.7 DHH
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[264]
SNU475 DHH
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[265]
THLE DHH
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[266]
liver DHH
Mean 0.03
Standard deviation 0.051
Values 0.11 0.014 0 0
[267]
ref_hepatocyte HHIP
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[268]
HepG2 HHIP
Mean 0.00788
Standard deviation 0.0051
Values 0.0043 0.011
[269]
HepG2.C3A HHIP
Mean 0
Standard deviation 0
Values 0 0
[270]
HuH.7 HHIP
Mean 0.00586
Standard deviation 0.0051
Values 0.0094 0 0.0082
[271]
SNU475 HHIP
Mean 0.035
Standard deviation 0.036
Values 0.061 0.0093
[272]
THLE HHIP
Mean 1.37
Standard deviation 0.85
Values 0.77 2
[273]
liver HHIP
Mean 5.1
Standard deviation 1.4
Values 4 6.3 3.8 6.4
[274]
ref_hepatocyte PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 PRKACG
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[276]
HepG2.C3A PRKACG
Mean 0
Standard deviation 0
Values 0 0
[277]
HuH.7 PRKACG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[278]
SNU475 PRKACG
Mean 0
Standard deviation 0
Values 0 0
[279]
THLE PRKACG
Mean 0
Standard deviation 0
Values 0 0
[280]
liver PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0
[281]
ref_hepatocyte CSNK1A1L
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[282]
HepG2 CSNK1A1L
Mean 0
Standard deviation 0
Values 0 0
[283]
HepG2.C3A CSNK1A1L
Mean 0
Standard deviation 0
Values 0 0
[284]
HuH.7 CSNK1A1L
Mean 0
Standard deviation 0
Values 0 0 0
[285]
SNU475 CSNK1A1L
Mean 0
Standard deviation 0
Values 0 0
[286]
THLE CSNK1A1L
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[287]
liver CSNK1A1L
Mean 0.114
Standard deviation 0.13
Values 0.3 0.1 0 0.051
[288]
ref_hepatocyte GRK3
Missing
[289]
HepG2 GRK3
Missing
[290]
HepG2.C3A GRK3
Missing
[291]
HuH.7 GRK3
Missing
[292]
SNU475 GRK3
Missing
[293]
THLE GRK3
Missing
[294]
liver GRK3
Missing
[295]
ref_hepatocyte GRK2
Missing
[296]
HepG2 GRK2
Missing
[297]
HepG2.C3A GRK2
Missing
[298]
HuH.7 GRK2
Missing
[299]
SNU475 GRK2
Missing
[300]
THLE GRK2
Missing
[301]
liver GRK2
Missing
[302]
ref_hepatocyte TPTEP2-CSNK1E
Missing
[303]
HepG2 TPTEP2-CSNK1E
Missing
[304]
HepG2.C3A TPTEP2-CSNK1E
Missing
[305]
HuH.7 TPTEP2-CSNK1E
Missing
[306]
SNU475 TPTEP2-CSNK1E
Missing
[307]
THLE TPTEP2-CSNK1E
Missing
[308]
liver TPTEP2-CSNK1E
Missing