WP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RPS6 | 40S ribosomal protein S6 | [1] | [2] | [3] | [4] | [5] | [6] | [7] |
2 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | [8] | -0.04[9] | -0.27[10] | -1.86[11] | 0.31[12] | -0.36[13] | -0.86[14] |
3 | RHEB | GTP-binding protein Rheb | [15] | -1.88[16] | -1.13[17] | -1.23[18] | -0.53[19] | -0.67[20] | -0.57[21] |
4 | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1 | [22] | -0.92[23] | -1.07[24] | -0.48[25] | -2.73[26] | -1.43[27] | -1.08[28] |
5 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [29] | 0.91[30] | -0.31[31] | -3.02[32] | -1.41[33] | 0.89[34] | -1.32[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | 0.15[37] | 0.09[38] | -1.01[39] | 0.52[40] | 0.29[41] | 0.27[42] |
7 | CTNNB1 | Catenin beta-1 | [43] | 1.69[44] | 1.36[45] | 2.22[46] | 1.33[47] | 1.30[48] | 1.62[49] |
8 | DDIT4 | DNA damage-inducible transcript 4 protein | [50] | 0.92[51] | 1.77[52] | 0.26[53] | -1.51[54] | 1.20[55] | -0.22[56] |
9 | CCND1 | G1/S-specific cyclin-D1 | [57] | 3.12[58] | 0.79[59] | 1.60[60] | 2.45[61] | 0.72[62] | 1.57[63] |
10 | MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1 | [64] | 0.06[65] | -0.02[66] | 0.18[67] | 0.65[68] | 0.59[69] | 0.33[70] |
11 | CDK4 | Cyclin-dependent kinase 4 | [71] | 1.40[72] | 2.16[73] | 1.76[74] | 0.75[75] | 1.15[76] | -0.32[77] |
12 | RPS6KB2 | Ribosomal protein S6 kinase beta-2 | [78] | [79] | [80] | [81] | [82] | [83] | [84] |
13 | NFKB2 | Nuclear factor NF-kappa-B p100 subunit | [85] | -0.70[86] | -0.22[87] | 0.20[88] | -0.81[89] | -0.21[90] | -2.50[91] |
14 | RELA | Transcription factor p65 | [92] | 0.20[93] | -0.13[94] | -0.01[95] | 0.52[96] | 0.17[97] | -0.36[98] |
15 | NFE2L2 | Nuclear factor erythroid 2-related factor 2 | [99] | 0.83[100] | 1.94[101] | 1.52[102] | 1.04[103] | 1.02[104] | 0.69[105] |
16 | VEGFA | Vascular endothelial growth factor A | [106] | 1.29[107] | 2.80[108] | 1.38[109] | 1.01[110] | 1.47[111] | 1.30[112] |
17 | EIF4E | Eukaryotic translation initiation factor 4E | [113] | 0.21[114] | 1.21[115] | 0.55[116] | 0.30[117] | 1.07[118] | 0.69[119] |
18 | KEAP1 | Kelch-like ECH-associated protein 1 | [120] | 0.28[121] | 0.36[122] | 0.07[123] | -0.24[124] | 0.50[125] | 1.07[126] |
19 | NRAS | GTPase NRas | [127] | 0.70[128] | 1.31[129] | 1.69[130] | 1.57[131] | 0.89[132] | 0.27[133] |
20 | NUMB | Protein numb homolog | [134] | -0.37[135] | 0.88[136] | -0.03[137] | 0.85[138] | 0.77[139] | 0.74[140] |
21 | STK11 | Serine/threonine-protein kinase STK11 | [141] | -0.02[142] | 0.10[143] | 0.33[144] | -0.14[145] | -0.03[146] | -0.34[147] |
22 | HRAS | GTPase HRas | [148] | -0.94[149] | -1.47[150] | -2.29[151] | -0.38[152] | -0.84[153] | -2.14[154] |
23 | TGFBR2 | TGF-beta receptor type-2 | [155] | 2.89[156] | 2.53[157] | 2.16[158] | 1.64[159] | 3.10[160] | 2.02[161] |
24 | AKT2 | RAC-beta serine/threonine-protein kinase | [162] | 1.03[163] | 1.48[164] | 1.58[165] | 1.43[166] | 0.97[167] | 1.65[168] |
25 | BIRC2 | Baculoviral IAP repeat-containing protein 2 | [169] | 0.31[170] | 1.44[171] | 0.37[172] | 0.99[173] | 1.53[174] | 1.25[175] |
26 | MLST8 | Target of rapamycin complex subunit LST8 | [176] | -0.10[177] | 0.40[178] | 0.75[179] | -0.40[180] | -0.31[181] | -0.05[182] |
27 | AJUBA | LIM domain-containing protein ajuba | [183] | 2.60[184] | 1.26[185] | 3.19[186] | 1.81[187] | 0.62[188] | 1.07[189] |
28 | FADD | FAS-associated death domain protein | [190] | 0.11[191] | -0.43[192] | 0.27[193] | 2.51[194] | 0.07[195] | -1.25[196] |
29 | KRAS | GTPase KRas | [197] | -0.44[198] | -0.29[199] | 1.28[200] | 1.37[201] | 0.78[202] | 1.19[203] |
30 | CASP8 | Caspase-8 | [204] | 0.09[205] | 0.83[206] | -0.02[207] | 0.49[208] | -0.51[209] | -0.90[210] |
31 | PRKAA1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | [211] | -0.01[212] | 1.44[213] | 2.93[214] | 2.04[215] | 2.06[216] | 2.58[217] |
32 | FGFR3 | Fibroblast growth factor receptor 3 | [218] | 2.80[219] | 2.89[220] | 3.19[221] | -2.72[222] | -1.62[223] | 0.97[224] |
33 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [225] | -0.40[226] | -0.11[227] | 0.96[228] | 2.64[229] | 1.89[230] | 3.52[231] |
34 | SESN2 | Sestrin-2 | [232] | 0.86[233] | 0.40[234] | 0.97[235] | -0.45[236] | 0.08[237] | 0.76[238] |
35 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -0.47[239] | 1.10[240] | 1.27[241] | 0.01[242] | 1.01[243] | 3.00[244] | |
36 | ERBB2 | Receptor tyrosine-protein kinase erbB-2 | [245] | 2.44[246] | 1.44[247] | 2.58[248] | 1.83[249] | 1.18[250] | 0.67[251] |
37 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [252] | 0.74[253] | 0.59[254] | 0.36[255] | 0.33[256] | 0.98[257] | 0.97[258] |
38 | CUL3 | Cullin-3 | [259] | 0.69[260] | 1.77[261] | 1.47[262] | 2.04[263] | 1.87[264] | 1.46[265] |
39 | EGFR | Epidermal growth factor receptor | [266] | -0.63[267] | -0.83[268] | 2.03[269] | 1.01[270] | 1.37[271] | 3.17[272] |
40 | TP53 | Cellular tumor antigen p53 | [273] | 1.71[274] | 1.44[275] | 2.18[276] | 1.87[277] | 1.28[278] | 0.48[279] |
41 | NOTCH2 | Neurogenic locus notch homolog protein 2 | [280] | 0.20[281] | -5.35[282] | 2.10[283] | 3.61[284] | 4.15[285] | 3.84[286] |
42 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [287] | 1.94[288] | 2.34[289] | 2.93[290] | 1.28[291] | 1.59[292] | 0.23[293] |
43 | IRF6 | Interferon regulatory factor 6 | [294] | -5.95[295] | -6.15[296] | -7.08[297] | -2.87[298] | -2.98[299] | 2.24[300] |
44 | CDK6 | Cyclin-dependent kinase 6 | [301] | 2.12[302] | 2.99[303] | 1.37[304] | 1.49[305] | 2.04[306] | 2.59[307] |
45 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [308] | 2.40[309] | 3.77[310] | 2.45[311] | 2.01[312] | 2.15[313] | 3.02[314] |
46 | FAT1 | Protocadherin Fat 1 | [315] | 4.93[316] | 3.52[317] | 1.83[318] | 3.86[319] | 3.98[320] | 4.30[321] |
47 | MTOR | Serine/threonine-protein kinase mTOR | [322] | 2.60[323] | 3.79[324] | 3.33[325] | 3.26[326] | 3.08[327] | 3.97[328] |
48 | TSC2 | Tuberin | [329] | 1.89[330] | 1.59[331] | 2.25[332] | 1.77[333] | 2.04[334] | 2.60[335] |
49 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 1.28[336] | 1.96[337] | 2.10[338] | 1.62[339] | 1.53[340] | 1.67[341] | |
50 | SESN1 | Sestrin-1 | [342] | 1.36[343] | 1.86[344] | -0.68[345] | -0.31[346] | 0.66[347] | 1.22[348] |
51 | SMAD4 | Mothers against decapentaplegic homolog 4 | [349] | 1.46[350] | 2.27[351] | 2.21[352] | 2.48[353] | 2.60[354] | 3.31[355] |
52 | RB1 | Retinoblastoma-associated protein | [356] | 1.29[357] | 1.96[358] | 2.50[359] | 2.85[360] | 2.92[361] | 1.99[362] |
53 | E2F1 | Transcription factor E2F1 | [363] | 2.02[364] | 2.05[365] | 2.15[366] | 2.44[367] | 2.63[368] | -3.10[369] |
54 | MAML1 | Mastermind-like protein 1 | [370] | 2.18[371] | 2.32[372] | 2.84[373] | 2.82[374] | 2.70[375] | 1.60[376] |
55 | RPTOR | Regulatory-associated protein of mTOR | [377] | 3.16[378] | 2.57[379] | 2.64[380] | 2.42[381] | 2.40[382] | 2.85[383] |
56 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.31[384] | 1.50[385] | 1.67[386] | 1.70[387] | 1.65[388] | 2.43[389] | |
57 | TSC1 | Hamartin | [390] | 1.96[391] | 2.79[392] | 2.92[393] | 2.63[394] | 2.59[395] | 3.27[396] |
58 | RICTOR | Rapamycin-insensitive companion of mTOR | [397] | 0.80[398] | 3.05[399] | 3.70[400] | 2.93[401] | 2.88[402] | 4.03[403] |
59 | FGFR2 | Fibroblast growth factor receptor 2 | [404] | -2.44[405] | -1.06[406] | 2.86[407] | 2.03[408] | -3.06[409] | 3.94[410] |
60 | TRAF3 | TNF receptor-associated factor 3 | [411] | 2.96[412] | 2.55[413] | 2.13[414] | 3.40[415] | 3.56[416] | 2.44[417] |
61 | FGFR1 | Fibroblast growth factor receptor 1 | [418] | 4.65[419] | 3.14[420] | 4.76[421] | 5.63[422] | 4.64[423] | 2.18[424] |
62 | GAB1 | GRB2-associated-binding protein 1 | [425] | 1.37[426] | 2.63[427] | 2.73[428] | 2.51[429] | 2.11[430] | 3.39[431] |
63 | PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | [432] | 3.10[433] | 3.73[434] | 3.73[435] | 3.62[436] | 1.41[437] | 2.37[438] |
64 | IGF1R | Insulin-like growth factor 1 receptor | [439] | 4.81[440] | 4.30[441] | 2.94[442] | 5.04[443] | 4.34[444] | 2.61[445] |
65 | NOTCH1 | Neurogenic locus notch homolog protein 1 | [446] | 1.97[447] | 0.99[448] | 2.30[449] | 3.16[450] | 3.26[451] | 5.15[452] |
66 | REL | Proto-oncogene c-Rel | [453] | -0.44[454] | 1.49[455] | 1.40[456] | 0.72[457] | 0.62[458] | 2.86[459] |
67 | AKT3 | RAC-gamma serine/threonine-protein kinase | [460] | -1.77[461] | -4.16[462] | -3.49[463] | 6.42[464] | 5.12[465] | 4.13[466] |
68 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [467] | -7.10[468] | [469] | -2.31[470] | -3.35[471] | -3.26[472] | 2.86[473] |
69 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [474] | 4.15[475] | 2.09[476] | 5.48[477] | 5.78[478] | 7.31[479] | -1.64[480] |
70 | TERT | Telomerase reverse transcriptase | [481] | 3.56[482] | 3.49[483] | 4.40[484] | 2.75[485] | -3.54[486] | -3.38[487] |
71 | TP63 | Tumor protein 63 | [488] | [489] | [490] | -1.85[491] | -0.80[492] | -4.63[493] | -0.96[494] |
72 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [495] | [496] | [497] | 1.91[498] | -3.22[499] | 4.62[500] | |
73 | CSMD3 | CUB and sushi domain-containing protein 3 | [501] | 8.98[502] | 8.11[503] | 7.57[504] | 5.92[505] | 7.75[506] | 3.91[507] |
74 | ENSG00000284930 | [508] | [509] | [510] | [511] | [512] | [513] | [514] | |
75 | MIR6869 | [515] | [516] | [517] | [518] | [519] | [520] | [521] | |
76 | MIRLET7C | [522] | [523] | [524] | [525] | [526] | [527] | [528] |