WP_GLYCOLYSIS_AND_GLUCONEOGENESIS |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
GAPDH |
Glyceraldehyde-3-phosphate dehydrogenase |
[1] |
-0.39[2] |
-0.43[3] |
0.37[4] |
-0.51[5] |
-0.04[6] |
-1.03[7] |
2 |
ALDOB |
Fructose-bisphosphate aldolase B |
[8] |
-11.47[9] |
-11.00[10] |
-11.02[11] |
-14.89[12] |
-15.64[13] |
0.21[14] |
3 |
ENO1 |
Alpha-enolase |
[15] |
0.37[16] |
1.04[17] |
0.21[18] |
0.66[19] |
0.14[20] |
-1.32[21] |
4 |
LDHA |
L-lactate dehydrogenase A chain |
[22] |
-0.03[23] |
0.13[24] |
0.30[25] |
0.00[26] |
-0.37[27] |
0.29[28] |
5 |
TPI1 |
Triosephosphate isomerase |
[29] |
-0.29[30] |
-0.20[31] |
0.40[32] |
-0.79[33] |
0.28[34] |
-0.39[35] |
6 |
PCK1 |
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
[36] |
-9.39[37] |
-4.93[38] |
-12.59[39] |
[40] |
-16.51[41] |
1.10[42] |
7 |
ALDOA |
Fructose-bisphosphate aldolase A |
[43] |
1.86[44] |
1.70[45] |
0.77[46] |
1.17[47] |
0.95[48] |
-1.14[49] |
8 |
MDH2 |
Malate dehydrogenase, mitochondrial |
[50] |
-1.44[51] |
-1.72[52] |
-1.22[53] |
-1.55[54] |
-1.88[55] |
-0.43[56] |
9 |
PGK1 |
Phosphoglycerate kinase 1 |
[57] |
1.01[58] |
0.37[59] |
0.24[60] |
1.39[61] |
0.96[62] |
-0.21[63] |
10 |
FBP1 |
Fructose-1,6-bisphosphatase 1 |
[64] |
-11.51[65] |
-9.87[66] |
-8.20[67] |
-12.41[68] |
-13.55[69] |
0.70[70] |
11 |
PGAM1 |
Phosphoglycerate mutase 1 |
[71] |
0.35[72] |
0.54[73] |
0.60[74] |
-0.11[75] |
0.63[76] |
-0.73[77] |
12 |
GOT1 |
Aspartate aminotransferase, cytoplasmic |
[78] |
-1.64[79] |
0.22[80] |
-1.32[81] |
-3.82[82] |
-2.66[83] |
0.43[84] |
13 |
MDH1 |
Malate dehydrogenase, cytoplasmic |
[85] |
-0.98[86] |
-0.15[87] |
-0.71[88] |
-0.50[89] |
-0.64[90] |
-0.54[91] |
14 |
GOT2 |
Aspartate aminotransferase, mitochondrial |
[92] |
-0.76[93] |
-0.98[94] |
-0.79[95] |
-1.73[96] |
-0.44[97] |
0.76[98] |
15 |
SLC2A2 |
Solute carrier family 2, facilitated glucose transporter member 2 |
[99] |
-3.54[100] |
-2.55[101] |
-1.89[102] |
-6.77[103] |
-10.90[104] |
1.88[105] |
16 |
PC |
Pyruvate carboxylase, mitochondrial |
[106] |
-1.61[107] |
-1.19[108] |
0.01[109] |
-1.57[110] |
-3.80[111] |
2.18[112] |
17 |
DLD |
Dihydrolipoyl dehydrogenase, mitochondrial |
[113] |
-1.48[114] |
-0.56[115] |
-0.71[116] |
-0.26[117] |
-0.57[118] |
0.13[119] |
18 |
GPI |
Glucose-6-phosphate isomerase |
[120] |
1.43[121] |
0.90[122] |
1.70[123] |
1.70[124] |
1.64[125] |
1.87[126] |
19 |
ENO3 |
Beta-enolase |
[127] |
-2.60[128] |
-2.27[129] |
-4.32[130] |
-2.14[131] |
-5.35[132] |
-0.80[133] |
20 |
PDHA1 |
Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial |
-1.12[134] |
-0.92[135] |
0.11[136] |
-0.53[137] |
-0.76[138] |
0.19[139] |
21 |
PFKL |
ATP-dependent 6-phosphofructokinase, liver type |
[140] |
0.75[141] |
1.01[142] |
0.88[143] |
0.58[144] |
0.38[145] |
0.74[146] |
22 |
LDHB |
L-lactate dehydrogenase B chain |
[147] |
-9.30[148] |
-9.17[149] |
-7.57[150] |
-3.23[151] |
3.33[152] |
-1.10[153] |
23 |
ALDOC |
Fructose-bisphosphate aldolase C |
[154] |
-1.89[155] |
-0.15[156] |
0.63[157] |
-0.97[158] |
-2.41[159] |
0.38[160] |
24 |
PFKP |
ATP-dependent 6-phosphofructokinase, platelet type |
[161] |
-0.54[162] |
-2.08[163] |
-6.72[164] |
3.56[165] |
2.45[166] |
-2.91[167] |
25 |
SLC2A3 |
Solute carrier family 2, facilitated glucose transporter member 3 |
[168] |
4.28[169] |
1.54[170] |
-4.96[171] |
-1.73[172] |
0.67[173] |
-1.25[174] |
26 |
DLAT |
Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial |
0.48[175] |
0.50[176] |
0.98[177] |
1.01[178] |
0.77[179] |
0.39[180] |
27 |
PKLR |
Pyruvate kinase PKLR |
[181] |
-2.21[182] |
-0.12[183] |
-1.83[184] |
-10.17[185] |
-9.84[186] |
1.00[187] |
28 |
SLC2A1 |
Solute carrier family 2, facilitated glucose transporter member 1 |
[188] |
6.30[189] |
3.53[190] |
2.61[191] |
3.46[192] |
2.82[193] |
-1.31[194] |
29 |
HK1 |
Hexokinase-1 |
[195] |
0.57[196] |
-4.11[197] |
-5.36[198] |
4.54[199] |
4.82[200] |
0.95[201] |
30 |
ENO2 |
Gamma-enolase |
[202] |
4.26[203] |
3.23[204] |
1.05[205] |
2.66[206] |
3.86[207] |
-1.68[208] |
31 |
PFKM |
ATP-dependent 6-phosphofructokinase, muscle type |
[209] |
-1.91[210] |
-1.10[211] |
3.91[212] |
3.35[213] |
3.99[214] |
0.95[215] |
32 |
HK2 |
Hexokinase-2 |
[216] |
5.54[217] |
6.10[218] |
5.18[219] |
3.87[220] |
4.88[221] |
0.58[222] |
33 |
GCK |
Glucokinase |
[223] |
-8.29[224] |
-6.08[225] |
-9.26[226] |
-6.91[227] |
-4.73[228] |
1.96[229] |
34 |
HK3 |
Hexokinase-3 |
[230] |
-8.18[231] |
-7.90[232] |
-8.80[233] |
-5.49[234] |
-8.45[235] |
3.01[236] |
35 |
SLC2A4 |
Solute carrier family 2, facilitated glucose transporter member 4 |
[237] |
1.48[238] |
1.94[239] |
2.57[240] |
-2.12[241] |
-2.62[242] |
1.48[243] |
36 |
PGAM2 |
Phosphoglycerate mutase 2 |
[244] |
-2.43[245] |
-0.12[246] |
0.18[247] |
-0.60[248] |
-1.34[249] |
0.45[250] |
37 |
LDHC |
L-lactate dehydrogenase C chain |
[251] |
[252] |
-7.79[253] |
-6.90[254] |
-1.51[255] |
-5.08[256] |
-0.42[257] |
38 |
FBP2 |
Fructose-1,6-bisphosphatase isozyme 2 |
[258] |
-1.75[259] |
-0.66[260] |
0.49[261] |
-3.13[262] |
-6.22[263] |
-2.53[264] |
39 |
SLC2A5 |
Solute carrier family 2, facilitated glucose transporter member 5 |
[265] |
1.25[266] |
-0.83[267] |
-4.07[268] |
4.06[269] |
1.66[270] |
-1.80[271] |
40 |
LDHAL6B |
L-lactate dehydrogenase A-like 6B |
[272] |
-4.11[273] |
0.69[274] |
-0.75[275] |
1.89[276] |
0.18[277] |
4.54[278] |
41 |
MPC1 |
Mitochondrial pyruvate carrier 1 |
[279] |
[280] |
[281] |
[282] |
[283] |
[284] |
[285] |
42 |
G6PC1 |
|
[286] |
[287] |
[288] |
[289] |
[290] |
[291] |
[292] |
43 |
PGK2 |
Phosphoglycerate kinase 2 |
[293] |
[294] |
[295] |
[296] |
[297] |
[298] |
[299] |
44 |
MPC2 |
Mitochondrial pyruvate carrier 2 |
[300] |
[301] |
[302] |
[303] |
[304] |
[305] |
[306] |
45 |
PKM |
Pyruvate kinase PKM |
[307] |
[308] |
[309] |
[310] |
[311] |
[312] |
[313] |
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