WP_GLUCURONIDATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UGT1A6 UDP-glucuronosyltransferase 1-6 [1] -6.14[2] -14.61[3] -7.68[4] -5.28[5] -10.46[6] -3.61[7]
2 UGT2B4 UDP-glucuronosyltransferase 2B4 [8] -6.76[9] -7.65[10] -1.37[11] -8.52[12] -11.35[13] 1.05[14]
3 UGDH UDP-glucose 6-dehydrogenase [15] 1.66[16] 0.85[17] 0.82[18] 1.18[19] -1.31[20] -0.29[21]
4 UGP2 UTP--glucose-1-phosphate uridylyltransferase [22] 0.50[23] 0.40[24] 0.86[25] 0.79[26] 0.96[27] 0.03[28]
5 UGT2B7 UDP-glucuronosyltransferase 2B7 [29] -0.65[30] -1.23[31] -5.65[32] -9.73[33] -10.64[34] -0.24[35]
6 UGT2B10 UDP-glucuronosyltransferase 2B10 [36] -1.08[37] 0.83[38] -5.78[39] -9.86[40] -12.68[41] -1.32[42]
7 UGT2B15 UDP-glucuronosyltransferase 2B15 [43] -8.99[44] -8.15[45] -6.41[46] -9.60[47] -9.49[48] -0.70[49]
8 UGT1A1 UDP-glucuronosyltransferase 1-1 [50] -3.68[51] -10.65[52] -4.45[53] 0.24[54] -9.10[55] 0.23[56]
9 UGT1A4 UDP-glucuronosyltransferase 1-4 [57] -11.05[58] [59] -10.35[60] -9.04[61] [62] 0.42[63]
10 PGM1 Phosphoglucomutase-1 [64] 1.27[65] 1.37[66] 2.93[67] 1.42[68] 1.54[69] 1.01[70]
11 PGM3 Phosphoacetylglucosamine mutase [71] 2.71[72] 3.20[73] 3.48[74] 2.94[75] 3.68[76] 1.17[77]
12 UGT1A9 UDP-glucuronosyltransferase 1-9 [78] -5.02[79] -10.61[80] -5.76[81] -4.09[82] -8.69[83] -0.35[84]
13 UGT2B17 UDP-glucuronosyltransferase 2B17 [85] -8.34[86] -8.44[87] -10.21[88] [89] [90] -1.07[91]
14 UGT2A3 UDP-glucuronosyltransferase 2A3 [92] 3.97[93] 5.11[94] -1.26[95] -4.46[96] -6.64[97] 1.79[98]
15 PGM2 Phosphoglucomutase-2 [99] 3.45[100] 2.85[101] 4.07[102] 3.41[103] 5.09[104] 0.29[105]
16 UGT1A3 UDP-glucuronosyltransferase 1-3 [106] -0.27[107] [108] -6.62[109] -3.83[110] -8.28[111] 1.52[112]
17 HK1 Hexokinase-1 [113] 3.61[114] -2.01[115] -2.24[116] 7.11[117] 7.82[118] 1.19[119]
18 UGT2A2 [120] [121] [122] [123] [124] [125] [126]
19 UGT1A5 UDP-glucuronosyltransferase 1-5 [127] -3.56[128] [129] -4.43[130] -0.69[131] [132] 1.59[133]
20 UGT2B11 UDP-glucuronosyltransferase 2B11 [134] 2.90[135] 0.83[136] 3.12[137] -3.69[138] [139] 1.10[140]
21 UGT2B28 UDP-glucuronosyltransferase 2B28 [141] 2.67[142] 2.47[143] -0.74[144] -4.28[145] [146] 1.05[147]
22 PGM5 Phosphoglucomutase-like protein 5 [148] -2.54[149] -1.84[150] -2.65[151] 0.12[152] -1.25[153] 3.48[154]
23 UGT1A7 UDP-glucuronosyltransferase 1-7 [155] 1.86[156] [157] 1.45[158] 7.28[159] 2.57[160] 3.53[161]
24 UGT1A8 UDP-glucuronosyltransferase 1-8 [162] [163] [164] [165] [166] [167] [168]
25 UGT2A1 UDP-glucuronosyltransferase 2A1 [169] [170] [171] [172] [173] [174] [175]
26 UGT1A10 UDP-glucuronosyltransferase 1-10 [176] [177] [178] [179] [180] [181] [182]
[1]
ref_hepatocyte UGT1A6
Mean 242
Standard deviation 2.6e+02
Values 11 5.9e+02 4.3e+02 0.45 1.7e+02
[2]
HepG2 UGT1A6
Mean 1.17
Standard deviation 0.86
Values 0.56 1.8
[3]
HepG2.C3A UGT1A6
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[4]
HuH.7 UGT1A6
Mean 0.277
Standard deviation 0.33
Values 0.14 0.65 0.041
[5]
SNU475 UGT1A6
Mean 1.9
Standard deviation 0.11
Values 1.8 2
[6]
THLE UGT1A6
Mean 0.0372
Standard deviation 0.053
Values 0 0.074
[7]
liver UGT1A6
Mean 23.2
Standard deviation 17
Values 8.2 34 9 42
[8]
ref_hepatocyte UGT2B4
Mean 210
Standard deviation 2.5e+02
Values 15 5e+02 4.6e+02 0.056 68
[9]
HepG2 UGT2B4
Mean 0.666
Standard deviation 0.42
Values 0.37 0.96
[10]
HepG2.C3A UGT2B4
Mean 0.523
Standard deviation 0.23
Values 0.69 0.36
[11]
HuH.7 UGT2B4
Mean 19.1
Standard deviation 13
Values 12 34 11
[12]
SNU475 UGT2B4
Mean 0.176
Standard deviation 0.04
Values 0.15 0.2
[13]
THLE UGT2B4
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[14]
liver UGT2B4
Mean 509
Standard deviation 93
Values 4.3e+02 5.3e+02 4.5e+02 6.3e+02
[15]
ref_hepatocyte UGDH
Mean 162
Standard deviation 1.3e+02
Values 88 58 49 3.1e+02 3.1e+02
[16]
HepG2 UGDH
Mean 175
Standard deviation 29
Values 1.5e+02 2e+02
[17]
HepG2.C3A UGDH
Mean 146
Standard deviation 14
Values 1.6e+02 1.4e+02
[18]
HuH.7 UGDH
Mean 67
Standard deviation 29
Values 48 1e+02 53
[19]
SNU475 UGDH
Mean 113
Standard deviation 49
Values 78 1.5e+02
[20]
THLE UGDH
Mean 14.2
Standard deviation 2.7
Values 12 16
[21]
liver UGDH
Mean 155
Standard deviation 1.2e+02
Values 61 1.9e+02 56 3.2e+02
[22]
ref_hepatocyte UGP2
Mean 149
Standard deviation 1.1e+02
Values 44 1.9e+02 1.6e+02 46 3.1e+02
[23]
HepG2 UGP2
Mean 72.3
Standard deviation 27
Values 92 53
[24]
HepG2.C3A UGP2
Mean 98.6
Standard deviation 16
Values 1.1e+02 87
[25]
HuH.7 UGP2
Mean 63.6
Standard deviation 4.1
Values 63 68 60
[26]
SNU475 UGP2
Mean 79
Standard deviation 17
Values 67 91
[27]
THLE UGP2
Mean 63.1
Standard deviation 2.6
Values 65 61
[28]
liver UGP2
Mean 178
Standard deviation 1.6e+02
Values 89 85 4.1e+02 1.3e+02
[29]
ref_hepatocyte UGT2B7
Mean 122
Standard deviation 1.9e+02
Values 5.3 4.3e+02 1.6e+02 3.3 8.1
[30]
HepG2 UGT2B7
Mean 26.6
Standard deviation 9
Values 20 33
[31]
HepG2.C3A UGT2B7
Mean 26.2
Standard deviation 13
Values 35 17
[32]
HuH.7 UGT2B7
Mean 0.568
Standard deviation 0.44
Values 0.34 1.1 0.3
[33]
SNU475 UGT2B7
Mean 0.0439
Standard deviation 0.0096
Values 0.051 0.037
[34]
THLE UGT2B7
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[35]
liver UGT2B7
Mean 121
Standard deviation 61
Values 61 77 1.7e+02 1.7e+02
[36]
ref_hepatocyte UGT2B10
Mean 89.2
Standard deviation 1.3e+02
Values 2.6 3.1e+02 1.2e+02 13 1.3
[37]
HepG2 UGT2B10
Mean 14.5
Standard deviation 5.1
Values 18 11
[38]
HepG2.C3A UGT2B10
Mean 79.3
Standard deviation 33
Values 1e+02 56
[39]
HuH.7 UGT2B10
Mean 0.379
Standard deviation 0.38
Values 0.22 0.82 0.098
[40]
SNU475 UGT2B10
Mean 0.0293
Standard deviation 0.0087
Values 0.035 0.023
[41]
THLE UGT2B10
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver UGT2B10
Mean 41.7
Standard deviation 22
Values 50 68 16 33
[43]
ref_hepatocyte UGT2B15
Mean 72.3
Standard deviation 99
Values 3.3 2.3e+02 1.2e+02 0.2 13
[44]
HepG2 UGT2B15
Mean 0.0487
Standard deviation 0.004
Values 0.051 0.046
[45]
HepG2.C3A UGT2B15
Mean 0.127
Standard deviation 0.013
Values 0.12 0.14
[46]
HuH.7 UGT2B15
Mean 0.2
Standard deviation 0.22
Values 0.084 0.45 0.066
[47]
SNU475 UGT2B15
Mean 0.0285
Standard deviation 0.019
Values 0.015 0.042
[48]
THLE UGT2B15
Mean 0.0219
Standard deviation 0.014
Values 0.012 0.032
[49]
liver UGT2B15
Mean 52
Standard deviation 21
Values 21 56 66 64
[50]
ref_hepatocyte UGT1A1
Mean 67.2
Standard deviation 89
Values 15 96 2.1e+02 0.52 12
[51]
HepG2 UGT1A1
Mean 1.8
Standard deviation 0.2
Values 1.7 1.9
[52]
HepG2.C3A UGT1A1
Mean 0.0209
Standard deviation 0.016
Values 0.032 0.0097
[53]
HuH.7 UGT1A1
Mean 0.72
Standard deviation 0.5
Values 0.31 1.3 0.57
[54]
SNU475 UGT1A1
Mean 24.4
Standard deviation 21
Values 9.8 39
[55]
THLE UGT1A1
Mean 0.0266
Standard deviation 0.038
Values 0 0.053
[56]
liver UGT1A1
Mean 92.4
Standard deviation 46
Values 34 83 1.1e+02 1.4e+02
[57]
ref_hepatocyte UGT1A4
Mean 53.1
Standard deviation 73
Values 2.5 1.6e+02 99 0 4.2
[58]
HepG2 UGT1A4
Mean 0.00858
Standard deviation 0.012
Values 0.017 0
[59]
HepG2.C3A UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 UGT1A4
Mean 0.00954
Standard deviation 0.0096
Values 0.0094 0.019 0
[61]
SNU475 UGT1A4
Mean 0.031
Standard deviation 0.015
Values 0.02 0.042
[62]
THLE UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[63]
liver UGT1A4
Mean 83.1
Standard deviation 65
Values 32 95 36 1.7e+02
[64]
ref_hepatocyte PGM1
Mean 48.7
Standard deviation 37
Values 13 94 81 17 38
[65]
HepG2 PGM1
Mean 40.3
Standard deviation 11
Values 48 32
[66]
HepG2.C3A PGM1
Mean 63.1
Standard deviation 8.8
Values 57 69
[67]
HuH.7 PGM1
Mean 87
Standard deviation 8.2
Values 84 80 96
[68]
SNU475 PGM1
Mean 39.9
Standard deviation 9.8
Values 33 47
[69]
THLE PGM1
Mean 30.8
Standard deviation 0.38
Values 31 31
[70]
liver PGM1
Mean 114
Standard deviation 21
Values 1e+02 91 1.3e+02 1.3e+02
[71]
ref_hepatocyte PGM3
Mean 15.4
Standard deviation 7.1
Values 20 6.7 10 16 24
[72]
HepG2 PGM3
Mean 34.5
Standard deviation 15
Values 45 24
[73]
HepG2.C3A PGM3
Mean 71.1
Standard deviation 4.6
Values 68 74
[74]
HuH.7 PGM3
Mean 40.4
Standard deviation 8
Values 35 50 37
[75]
SNU475 PGM3
Mean 36.2
Standard deviation 5.4
Values 32 40
[76]
THLE PGM3
Mean 42.8
Standard deviation 0.97
Values 42 43
[77]
liver PGM3
Mean 40.4
Standard deviation 15
Values 45 54 19 44
[78]
ref_hepatocyte UGT1A9
Mean 15.2
Standard deviation 13
Values 2.6 27 26 0 21
[79]
HepG2 UGT1A9
Mean 0.16
Standard deviation 0.057
Values 0.12 0.2
[80]
HepG2.C3A UGT1A9
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[81]
HuH.7 UGT1A9
Mean 0.0656
Standard deviation 0.056
Values 0.0094 0.12 0.066
[82]
SNU475 UGT1A9
Mean 0.273
Standard deviation 0.34
Values 0.03 0.51
[83]
THLE UGT1A9
Mean 0.00798
Standard deviation 0.011
Values 0 0.016
[84]
liver UGT1A9
Mean 13.9
Standard deviation 9.6
Values 3 22 8.7 22
[85]
ref_hepatocyte UGT2B17
Mean 10.8
Standard deviation 16
Values 1.3 37 15 0 1.3
[86]
HepG2 UGT2B17
Mean 0.0114
Standard deviation 0.0081
Values 0.017 0.0057
[87]
HepG2.C3A UGT2B17
Mean 0.0156
Standard deviation 0.0083
Values 0.021 0.0097
[88]
HuH.7 UGT2B17
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[89]
SNU475 UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[90]
THLE UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[91]
liver UGT2B17
Mean 6
Standard deviation 4.8
Values 0.5 8.6 3.7 11
[92]
ref_hepatocyte UGT2A3
Mean 7.91
Standard deviation 6.4
Values 0.33 6.3 9.3 18 5.7
[93]
HepG2 UGT2A3
Mean 42.4
Standard deviation 14
Values 52 33
[94]
HepG2.C3A UGT2A3
Mean 137
Standard deviation 28
Values 1.6e+02 1.2e+02
[95]
HuH.7 UGT2A3
Mean 0.775
Standard deviation 0.72
Values 0.39 1.6 0.33
[96]
SNU475 UGT2A3
Mean 0.11
Standard deviation 0.13
Values 0.02 0.2
[97]
THLE UGT2A3
Mean 0.0172
Standard deviation 0.0092
Values 0.024 0.011
[98]
liver UGT2A3
Mean 31.9
Standard deviation 15
Values 24 24 55 25
[99]
ref_hepatocyte PGM2
Mean 4.67
Standard deviation 2.7
Values 4.4 2.9 1.3 6.5 8.2
[100]
HepG2 PGM2
Mean 17.6
Standard deviation 5.6
Values 22 14
[101]
HepG2.C3A PGM2
Mean 16.8
Standard deviation 7.6
Values 22 11
[102]
HuH.7 PGM2
Mean 18.4
Standard deviation 3.6
Values 20 14 20
[103]
SNU475 PGM2
Mean 15.2
Standard deviation 0.74
Values 15 16
[104]
THLE PGM2
Mean 34.5
Standard deviation 5.3
Values 31 38
[105]
liver PGM2
Mean 6.66
Standard deviation 1.3
Values 6.5 8.6 5.5 6
[106]
ref_hepatocyte UGT1A3
Mean 4.24
Standard deviation 4.8
Values 0.37 11 7.9 0 2.3
[107]
HepG2 UGT1A3
Mean 1.2
Standard deviation 0.2
Values 1.1 1.3
[108]
HepG2.C3A UGT1A3
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 UGT1A3
Mean 0.0101
Standard deviation 0.0024
Values 0.0094 0.013 0.0082
[110]
SNU475 UGT1A3
Mean 0.0911
Standard deviation 0.029
Values 0.071 0.11
[111]
THLE UGT1A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver UGT1A3
Mean 14.2
Standard deviation 12
Values 5.8 21 2.5 28
[113]
ref_hepatocyte HK1
Mean 1.86
Standard deviation 1.3
Values 3.7 1.4 1.9 0.099 2.2
[114]
HepG2 HK1
Mean 7.77
Standard deviation 3.6
Values 5.2 10
[115]
HepG2.C3A HK1
Mean 0.233
Standard deviation 0.056
Values 0.19 0.27
[116]
HuH.7 HK1
Mean 0.0926
Standard deviation 0.049
Values 0.037 0.11 0.13
[117]
SNU475 HK1
Mean 79.1
Standard deviation 12
Values 87 71
[118]
THLE HK1
Mean 91.7
Standard deviation 17
Values 80 1e+02
[119]
liver HK1
Mean 4.98
Standard deviation 1.7
Values 6.3 6.3 2.9 4.4
[120]
ref_hepatocyte UGT2A2
Mean 0.438
Standard deviation 0.59
Values 0 1.4 0.6 0 0.18
[121]
HepG2 UGT2A2
Missing
[122]
HepG2.C3A UGT2A2
Missing
[123]
HuH.7 UGT2A2
Missing
[124]
SNU475 UGT2A2
Missing
[125]
THLE UGT2A2
Missing
[126]
liver UGT2A2
Missing
[127]
ref_hepatocyte UGT1A5
Mean 0.393
Standard deviation 0.32
Values 0.19 0.58 0.82 0 0.38
[128]
HepG2 UGT1A5
Mean 0.0114
Standard deviation 0.0081
Values 0.017 0.0057
[129]
HepG2.C3A UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 UGT1A5
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[131]
SNU475 UGT1A5
Mean 0.0747
Standard deviation 0.012
Values 0.066 0.083
[132]
THLE UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[133]
liver UGT1A5
Mean 1.38
Standard deviation 1.4
Values 0.85 3.4 0.31 0.98
[134]
ref_hepatocyte UGT2B11
Mean 0.391
Standard deviation 0.65
Values 0 0.46 1.5 0 0
[135]
HepG2 UGT2B11
Mean 1
Standard deviation 0.2
Values 1.1 0.86
[136]
HepG2.C3A UGT2B11
Mean 0.348
Standard deviation 0.19
Values 0.48 0.21
[137]
HuH.7 UGT2B11
Mean 0.795
Standard deviation 0.79
Values 0.37 1.7 0.31
[138]
SNU475 UGT2B11
Mean 0.00928
Standard deviation 0.013
Values 0 0.019
[139]
THLE UGT2B11
Mean 0
Standard deviation 0
Values 0 0
[140]
liver UGT2B11
Mean 0.98
Standard deviation 0.68
Values 0.87 0.59 2 0.49
[141]
ref_hepatocyte UGT2B28
Mean 0.294
Standard deviation 0.52
Values 0 1.2 0.28 0 0
[142]
HepG2 UGT2B28
Mean 0.642
Standard deviation 0.23
Values 0.48 0.81
[143]
HepG2.C3A UGT2B28
Mean 0.816
Standard deviation 0.45
Values 1.1 0.5
[144]
HuH.7 UGT2B28
Mean 0.0413
Standard deviation 0.043
Values 0.0094 0.09 0.025
[145]
SNU475 UGT2B28
Mean 0.00464
Standard deviation 0.0066
Values 0 0.0093
[146]
THLE UGT2B28
Mean 0
Standard deviation 0
Values 0 0
[147]
liver UGT2B28
Mean 0.714
Standard deviation 0.87
Values 0.013 1.1 0 1.8
[148]
ref_hepatocyte PGM5
Mean 0.146
Standard deviation 0.17
Values 0.37 0.065 0.29 0 0
[149]
HepG2 PGM5
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[150]
HepG2.C3A PGM5
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[151]
HuH.7 PGM5
Mean 0.00547
Standard deviation 0.0095
Values 0 0 0.016
[152]
SNU475 PGM5
Mean 0.0485
Standard deviation 0.003
Values 0.051 0.046
[153]
THLE PGM5
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[154]
liver PGM5
Mean 1.9
Standard deviation 2
Values 4.6 2 0.54 0.41
[155]
ref_hepatocyte UGT1A7
Mean 0.0431
Standard deviation 0.096
Values 0 0 0.22 0 0
[156]
HepG2 UGT1A7
Mean 0.0537
Standard deviation 0.021
Values 0.039 0.069
[157]
HepG2.C3A UGT1A7
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 UGT1A7
Mean 0.0277
Standard deviation 0.011
Values 0.028 0.039 0.016
[159]
SNU475 UGT1A7
Mean 2.06
Standard deviation 1.2
Values 2.9 1.2
[160]
THLE UGT1A7
Mean 0.0556
Standard deviation 0.012
Values 0.047 0.064
[161]
liver UGT1A7
Mean 0.582
Standard deviation 0.83
Values 0.32 1.8 0.094 0.1
[162]
ref_hepatocyte UGT1A8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 UGT1A8
Mean 0.0407
Standard deviation 0.027
Values 0.019 0.071 0.033
[166]
SNU475 UGT1A8
Mean 0.152
Standard deviation 0.028
Values 0.13 0.17
[167]
THLE UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[168]
liver UGT1A8
Mean 0.0104
Standard deviation 0.014
Values 0.013 0.029 0 0
[169]
ref_hepatocyte UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 UGT2A1
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[171]
HepG2.C3A UGT2A1
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[172]
HuH.7 UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0
[173]
SNU475 UGT2A1
Mean 0.015
Standard deviation 0.015
Values 0.025 0.0046
[174]
THLE UGT2A1
Mean 0
Standard deviation 0
Values 0 0
[175]
liver UGT2A1
Mean 0.00999
Standard deviation 0.012
Values 0 0.014 0 0.026
[176]
ref_hepatocyte UGT1A10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 UGT1A10
Mean 0.00788
Standard deviation 0.0051
Values 0.0043 0.011
[178]
HepG2.C3A UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[179]
HuH.7 UGT1A10
Mean 0.115
Standard deviation 0.078
Values 0.075 0.21 0.066
[180]
SNU475 UGT1A10
Mean 0.012
Standard deviation 0.0027
Values 0.01 0.014
[181]
THLE UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[182]
liver UGT1A10
Mean 0.0104
Standard deviation 0.014
Values 0.013 0.029 0 0