WP_GENES_CONTROLLING_NEPHROGENESIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ITGB1 | Integrin beta-1 | [1] | -0.51[2] | -0.56[3] | -0.44[4] | 0.16[5] | 0.12[6] | -0.64[7] |
2 | CTNNB1 | Catenin beta-1 | [8] | 0.87[9] | 0.30[10] | 1.18[11] | -0.55[12] | -0.44[13] | 0.31[14] |
3 | ILK | Integrin-linked protein kinase | [15] | -1.55[16] | -1.68[17] | -1.76[18] | -1.76[19] | -2.77[20] | -2.25[21] |
4 | VEGFA | Vascular endothelial growth factor A | [22] | 0.47[23] | 1.74[24] | 0.33[25] | -0.86[26] | -0.28[27] | -0.02[28] |
5 | CD2AP | CD2-associated protein | [29] | -1.61[30] | -0.39[31] | -0.88[32] | -0.25[33] | -1.66[34] | -1.21[35] |
6 | LAMB2 | Laminin subunit beta-2 | [36] | 1.39[37] | 1.00[38] | -0.06[39] | -0.41[40] | 0.37[41] | 1.30[42] |
7 | NCK1 | Cytoplasmic protein NCK1 | [43] | -2.34[44] | -2.31[45] | -2.21[46] | -1.87[47] | -1.88[48] | -1.27[49] |
8 | NOTCH2 | Neurogenic locus notch homolog protein 2 | [50] | -0.61[51] | -6.41[52] | 1.05[53] | 1.73[54] | 2.40[55] | 2.53[56] |
9 | NCK2 | Cytoplasmic protein NCK2 | [57] | 0.05[58] | -0.43[59] | -2.03[60] | -1.63[61] | -1.01[62] | -1.62[63] |
10 | ITGA3 | Integrin alpha-3 | [64] | 1.21[65] | -3.57[66] | -4.56[67] | 3.08[68] | 2.65[69] | -2.28[70] |
11 | HNF1B | Hepatocyte nuclear factor 1-beta | [71] | -0.94[72] | -3.31[73] | 0.80[74] | -2.15[75] | -8.69[76] | -0.60[77] |
12 | CXCR4 | C-X-C chemokine receptor type 4 | [78] | -2.61[79] | [80] | -3.16[81] | -6.86[82] | -3.15[83] | -0.86[84] |
13 | CD36 | Platelet glycoprotein 4 | [85] | 0.59[86] | -0.16[87] | -5.25[88] | 1.88[89] | -7.24[90] | 2.29[91] |
14 | FGFR2 | Fibroblast growth factor receptor 2 | [92] | -3.25[93] | -2.12[94] | 1.81[95] | 0.15[96] | -4.81[97] | 2.63[98] |
15 | SHH | Sonic hedgehog protein | [99] | -0.36[100] | -0.58[101] | -0.52[102] | -8.48[103] | -8.75[104] | -0.67[105] |
16 | CXCL12 | Stromal cell-derived factor 1 | [106] | -7.33[107] | -6.84[108] | -6.31[109] | 2.18[110] | 3.75[111] | 3.73[112] |
17 | PDGFB | Platelet-derived growth factor subunit B | [113] | 2.31[114] | 2.11[115] | -0.72[116] | -1.24[117] | -1.79[118] | -0.43[119] |
18 | RET | Proto-oncogene tyrosine-protein kinase receptor Ret | [120] | -6.31[121] | -7.66[122] | [123] | -7.27[124] | -4.44[125] | -0.20[126] |
19 | ETV4 | ETS translocation variant 4 | [127] | 5.14[128] | 5.88[129] | 5.38[130] | 0.57[131] | 2.06[132] | -2.36[133] |
20 | PDGFRB | Platelet-derived growth factor receptor beta | [134] | 0.55[135] | 0.88[136] | -1.58[137] | 0.55[138] | 0.99[139] | 2.62[140] |
21 | SIX1 | Homeobox protein SIX1 | [141] | 1.67[142] | 1.41[143] | -0.16[144] | 1.91[145] | -2.81[146] | -5.75[147] |
22 | KDR | Vascular endothelial growth factor receptor 2 | [148] | -6.37[149] | -8.09[150] | -7.40[151] | -3.04[152] | 3.30[153] | 5.50[154] |
23 | WNT4 | Protein Wnt-4 | [155] | -4.43[156] | -3.64[157] | -4.76[158] | -2.67[159] | -4.11[160] | -0.58[161] |
24 | FOXC1 | Forkhead box protein C1 | [162] | 2.47[163] | 0.26[164] | 1.68[165] | 2.05[166] | 2.19[167] | -1.25[168] |
25 | SLIT2 | Slit homolog 2 protein | [169] | -1.99[170] | -6.00[171] | -1.01[172] | 0.88[173] | 0.22[174] | 2.20[175] |
26 | NPHS1 | Nephrin | [176] | 0.92[177] | 0.26[178] | -0.22[179] | -0.67[180] | -1.66[181] | -1.68[182] |
27 | GDNF | Glial cell line-derived neurotrophic factor | [183] | 4.21[184] | 2.24[185] | -3.62[186] | -2.62[187] | -0.83[188] | -0.93[189] |
28 | LMX1B | LIM homeobox transcription factor 1-beta | [190] | 0.45[191] | 0.93[192] | 2.76[193] | -0.23[194] | -0.61[195] | -1.01[196] |
29 | EMX2 | Homeobox protein EMX2 | [197] | [198] | -3.72[199] | [200] | -2.91[201] | -6.12[202] | -1.30[203] |
30 | FGF8 | Fibroblast growth factor 8 | [204] | -4.07[205] | -3.79[206] | 0.69[207] | -3.22[208] | [209] | 1.90[210] |
31 | ITGA8 | Integrin alpha-8 | [211] | [212] | -3.65[213] | -4.58[214] | 2.53[215] | [216] | 3.66[217] |
32 | GLI3 | Transcriptional activator GLI3 | [218] | -1.97[219] | [220] | -1.10[221] | 7.63[222] | 5.88[223] | 3.35[224] |
33 | ROBO2 | Roundabout homolog 2 | [225] | -3.13[226] | [227] | 7.37[228] | -1.24[229] | -1.04[230] | 5.42[231] |
34 | FOXD1 | Forkhead box protein D1 | [232] | [233] | [234] | [235] | [236] | [237] | [238] |
35 | KIRREL1 | Kin of IRRE-like protein 1 | [239] | [240] | [241] | [242] | [243] | [244] | [245] |
36 | WT1 | Wilms tumor protein | [246] | [247] | [248] | [249] | [250] | [251] | [252] |
37 | EYA1 | Eyes absent homolog 1 | [253] | [254] | [255] | [256] | [257] | [258] | [259] |
38 | TCF21 | Transcription factor 21 | [260] | [261] | [262] | [263] | [264] | [265] | [266] |
39 | HOXA11 | Homeobox protein Hox-A11 | [267] | [268] | [269] | [270] | [271] | [272] | [273] |
40 | FOXC2 | Forkhead box protein C2 | [274] | [275] | [276] | [277] | [278] | [279] | [280] |
41 | HOXD11 | Homeobox protein Hox-D11 | [281] | [282] | [283] | [284] | [285] | [286] | [287] |
42 | NPHS2 | Podocin | [288] | [289] | [290] | [291] | [292] | [293] | [294] |
43 | LHX1 | LIM/homeobox protein Lhx1 | [295] | [296] | [297] | [298] | [299] | [300] | [301] |
44 | PAX2 | Paired box protein Pax-2 | [302] | [303] | [304] | [305] | [306] | [307] | [308] |