WP_GENES_ASSOCIATED_WITH_THE_DEVELOPMENT_OF_RHEUMATOID_ARTHRITIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HLA-DRB1 HLA class II histocompatibility antigen, DRB1-15 beta chain [1] -8.64[2] [3] [4] -7.17[5] -12.82[6] -3.60[7]
2 IL6ST Interleukin-6 receptor subunit beta [8] 0.06[9] 0.97[10] 0.96[11] 0.66[12] 1.26[13] 1.84[14]
3 ITGAV Integrin alpha-V [15] 1.34[16] 0.80[17] 0.61[18] 1.21[19] 0.52[20] -1.51[21]
4 TRAF1 TNF receptor-associated factor 1 [22] -4.62[23] -5.09[24] -3.78[25] -4.61[26] -4.61[27] -4.84[28]
5 CD40 Tumor necrosis factor receptor superfamily member 5 [29] -1.00[30] -2.54[31] -10.32[32] -3.89[33] -3.13[34] -2.87[35]
6 PHF19 PHD finger protein 19 [36] 1.57[37] 1.36[38] 1.35[39] 0.80[40] 1.07[41] -3.24[42]
7 IRF5 Interferon regulatory factor 5 [43] 0.10[44] -0.45[45] -1.16[46] -0.71[47] -3.55[48] -0.96[49]
8 STAT4 Signal transducer and activator of transcription 4 [50] -5.04[51] -4.31[52] -3.32[53] 0.57[54] -1.20[55] -0.91[56]
9 SLC22A4 Solute carrier family 22 member 4 [57] -2.40[58] -2.39[59] -4.28[60] -1.10[61] -0.76[62] -2.10[63]
10 CCR6 C-C chemokine receptor type 6 [64] 2.01[65] 2.33[66] 4.15[67] -2.56[68] -3.77[69] -2.24[70]
11 CD244 Natural killer cell receptor 2B4 [71] [72] [73] -2.72[74] [75] -3.27[76] -0.15[77]
12 CIITA MHC class II transactivator [78] -2.58[79] -3.10[80] -4.55[81] -1.72[82] -1.14[83] 0.97[84]
13 IL2RA Interleukin-2 receptor subunit alpha [85] [86] -6.13[87] [88] -5.67[89] -8.15[90] -1.41[91]
14 BLK Tyrosine-protein kinase Blk [92] -3.73[93] -3.73[94] [95] [96] -4.27[97] 0.24[98]
15 PTPN22 Tyrosine-protein phosphatase non-receptor type 22 [99] -6.86[100] -4.21[101] -3.20[102] -1.95[103] 3.12[104] 0.79[105]
16 FCRL3 Fc receptor-like protein 3 [106] [107] [108] [109] [110] [111] 0.54[112]
17 PADI4 Protein-arginine deiminase type-4 [113] 3.39[114] 0.42[115] [116] -3.30[117] [118] 3.26[119]
18 CTLA4 Cytotoxic T-lymphocyte protein 4 [120] [121] [122] [123] [124] [125] [126]
[1]
ref_hepatocyte HLA-DRB1
Mean 19
Standard deviation 28
Values 4 66 24 0 0.7
[2]
HepG2 HLA-DRB1
Mean 0.121
Standard deviation 0.017
Values 0.13 0.11
[3]
HepG2.C3A HLA-DRB1
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 HLA-DRB1
Mean 0
Standard deviation 0
Values 0 0 0
[5]
SNU475 HLA-DRB1
Mean 0.506
Standard deviation 0.45
Values 0.83 0.19
[6]
THLE HLA-DRB1
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[7]
liver HLA-DRB1
Mean 8.55
Standard deviation 3.8
Values 4.6 6.5 10 13
[8]
ref_hepatocyte IL6ST
Mean 16.5
Standard deviation 5.8
Values 9.5 19 12 24 18
[9]
HepG2 IL6ST
Mean 43.6
Standard deviation 25
Values 61 26
[10]
HepG2.C3A IL6ST
Mean 92.3
Standard deviation 8.3
Values 98 86
[11]
HuH.7 IL6ST
Mean 63.5
Standard deviation 38
Values 35 1.1e+02 50
[12]
SNU475 IL6ST
Mean 100
Standard deviation 15
Values 1.1e+02 90
[13]
THLE IL6ST
Mean 252
Standard deviation 68
Values 3e+02 2e+02
[14]
liver IL6ST
Mean 321
Standard deviation 1.1e+02
Values 4.1e+02 4.2e+02 2.5e+02 2.1e+02
[15]
ref_hepatocyte ITGAV
Mean 15.6
Standard deviation 20
Values 13 2.7 2.1 9.2 51
[16]
HepG2 ITGAV
Mean 100
Standard deviation 13
Values 1.1e+02 91
[17]
HepG2.C3A ITGAV
Mean 77.8
Standard deviation 11
Values 85 70
[18]
HuH.7 ITGAV
Mean 47.4
Standard deviation 14
Values 32 58 52
[19]
SNU475 ITGAV
Mean 139
Standard deviation 57
Values 99 1.8e+02
[20]
THLE ITGAV
Mean 144
Standard deviation 29
Values 1.2e+02 1.6e+02
[21]
liver ITGAV
Mean 30
Standard deviation 16
Values 39 48 20 13
[22]
ref_hepatocyte TRAF1
Mean 7.51
Standard deviation 9.8
Values 19 0.64 0.39 0.064 17
[23]
HepG2 TRAF1
Mean 0.773
Standard deviation 0.67
Values 0.3 1.2
[24]
HepG2.C3A TRAF1
Mean 0.631
Standard deviation 0.33
Values 0.4 0.87
[25]
HuH.7 TRAF1
Mean 1.09
Standard deviation 0.11
Values 1.1 1.2 0.96
[26]
SNU475 TRAF1
Mean 1.19
Standard deviation 0.16
Values 1.3 1.1
[27]
THLE TRAF1
Mean 1.97
Standard deviation 0.35
Values 1.7 2.2
[28]
liver TRAF1
Mean 1.43
Standard deviation 0.57
Values 2.1 1.7 0.89 1.1
[29]
ref_hepatocyte CD40
Mean 4.89
Standard deviation 3.8
Values 8.5 7.3 7.1 0 1.6
[30]
HepG2 CD40
Mean 6.2
Standard deviation 2.8
Values 4.2 8.2
[31]
HepG2.C3A CD40
Mean 2.41
Standard deviation 0.21
Values 2.3 2.6
[32]
HuH.7 CD40
Mean 0.00761
Standard deviation 0.0083
Values 0 0.0064 0.016
[33]
SNU475 CD40
Mean 1.27
Standard deviation 0.3
Values 1.5 1.1
[34]
THLE CD40
Mean 3.58
Standard deviation 1.1
Values 4.4 2.8
[35]
liver CD40
Mean 3.64
Standard deviation 2.1
Values 2.1 2 4.1 6.4
[36]
ref_hepatocyte PHF19
Mean 2.35
Standard deviation 2.3
Values 6.5 1.2 1.5 1.1 1.4
[37]
HepG2 PHF19
Mean 17.6
Standard deviation 4.5
Values 21 14
[38]
HepG2.C3A PHF19
Mean 17.2
Standard deviation 6.4
Values 22 13
[39]
HuH.7 PHF19
Mean 11.9
Standard deviation 6.7
Values 18 4.4 14
[40]
SNU475 PHF19
Mean 15.7
Standard deviation 0.85
Values 15 16
[41]
THLE PHF19
Mean 31.5
Standard deviation 9.1
Values 25 38
[42]
liver PHF19
Mean 1.35
Standard deviation 0.52
Values 1.4 2.1 0.85 1.1
[43]
ref_hepatocyte IRF5
Mean 0.992
Standard deviation 0.31
Values 1.5 0.97 0.83 0.82 0.82
[44]
HepG2 IRF5
Mean 2.69
Standard deviation 0.71
Values 2.2 3.2
[45]
HepG2.C3A IRF5
Mean 2.07
Standard deviation 0.044
Values 2 2.1
[46]
HuH.7 IRF5
Mean 0.882
Standard deviation 0.44
Values 0.54 1.4 0.72
[47]
SNU475 IRF5
Mean 2.33
Standard deviation 0.55
Values 1.9 2.7
[48]
THLE IRF5
Mean 0.543
Standard deviation 0.053
Values 0.58 0.51
[49]
liver IRF5
Mean 2.78
Standard deviation 0.92
Values 2.3 1.8 3.9 3.1
[50]
ref_hepatocyte STAT4
Mean 0.825
Standard deviation 0.62
Values 0.35 1.3 1 0 1.4
[51]
HepG2 STAT4
Mean 0.0637
Standard deviation 0.025
Values 0.082 0.046
[52]
HepG2.C3A STAT4
Mean 0.119
Standard deviation 0.044
Values 0.15 0.087
[53]
HuH.7 STAT4
Mean 0.164
Standard deviation 0.023
Values 0.19 0.14 0.16
[54]
SNU475 STAT4
Mean 4.7
Standard deviation 1.3
Values 3.8 5.6
[55]
THLE STAT4
Mean 2.3
Standard deviation 1.2
Values 3.1 1.5
[56]
liver STAT4
Mean 2.39
Standard deviation 1.1
Values 3.7 1.5 3 1.4
[57]
ref_hepatocyte SLC22A4
Mean 0.588
Standard deviation 0.5
Values 0.69 0.3 1.4 0.37 0.16
[58]
HepG2 SLC22A4
Mean 0.283
Standard deviation 0.0054
Values 0.28 0.29
[59]
HepG2.C3A SLC22A4
Mean 0.319
Standard deviation 0.094
Values 0.39 0.25
[60]
HuH.7 SLC22A4
Mean 0.0603
Standard deviation 0.062
Values 0 0.058 0.12
[61]
SNU475 SLC22A4
Mean 1.05
Standard deviation 0.35
Values 1.3 0.81
[62]
THLE SLC22A4
Mean 2.23
Standard deviation 0.54
Values 1.8 2.6
[63]
liver SLC22A4
Mean 0.746
Standard deviation 0.54
Values 1.2 1.2 0.28 0.28
[64]
ref_hepatocyte CCR6
Mean 0.363
Standard deviation 0.58
Values 0.033 0.081 0.14 1.4 0.16
[65]
HepG2 CCR6
Mean 3.72
Standard deviation 0.62
Values 4.2 3.3
[66]
HepG2.C3A CCR6
Mean 5.21
Standard deviation 1.6
Values 6.3 4.1
[67]
HuH.7 CCR6
Mean 12.8
Standard deviation 4.7
Values 16 7.3 15
[68]
SNU475 CCR6
Mean 0.236
Standard deviation 0.12
Values 0.32 0.15
[69]
THLE CCR6
Mean 0.171
Standard deviation 0.068
Values 0.22 0.12
[70]
liver CCR6
Mean 0.417
Standard deviation 0.15
Values 0.54 0.43 0.49 0.21
[71]
ref_hepatocyte CD244
Mean 0.205
Standard deviation 0.31
Values 0 0.69 0.34 0 0
[72]
HepG2 CD244
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A CD244
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 CD244
Mean 0.062
Standard deviation 0.048
Values 0.0094 0.1 0.074
[75]
SNU475 CD244
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE CD244
Mean 0.136
Standard deviation 0.025
Values 0.12 0.15
[77]
liver CD244
Mean 1.01
Standard deviation 0.16
Values 1.1 0.8 0.99 1.1
[78]
ref_hepatocyte CIITA
Mean 0.181
Standard deviation 0.21
Values 0.26 0.5 0.16 0 0
[79]
HepG2 CIITA
Mean 0.0766
Standard deviation 0.0052
Values 0.073 0.08
[80]
HepG2.C3A CIITA
Mean 0.0603
Standard deviation 0.025
Values 0.043 0.078
[81]
HuH.7 CIITA
Mean 0.0154
Standard deviation 0.0062
Values 0.019 0.019 0.0082
[82]
SNU475 CIITA
Mean 0.211
Standard deviation 0.13
Values 0.12 0.31
[83]
THLE CIITA
Mean 0.527
Standard deviation 0.17
Values 0.64 0.41
[84]
liver CIITA
Mean 1.93
Standard deviation 1.4
Values 3.6 2.6 0.75 0.74
[85]
ref_hepatocyte IL2RA
Mean 0.131
Standard deviation 0.1
Values 0.19 0.057 0 0.15 0.26
[86]
HepG2 IL2RA
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A IL2RA
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[88]
HuH.7 IL2RA
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 IL2RA
Mean 0.00992
Standard deviation 0.0075
Values 0.015 0.0046
[90]
THLE IL2RA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[91]
liver IL2RA
Mean 0.27
Standard deviation 0.33
Values 0.75 0.2 0.024 0.1
[92]
ref_hepatocyte BLK
Mean 0.12
Standard deviation 0.12
Values 0.28 0.15 0.16 0 0
[93]
HepG2 BLK
Mean 0.0229
Standard deviation 0.0081
Values 0.017 0.029
[94]
HepG2.C3A BLK
Mean 0.0258
Standard deviation 0.009
Values 0.032 0.019
[95]
HuH.7 BLK
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 BLK
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE BLK
Mean 0.0399
Standard deviation 0.019
Values 0.053 0.027
[98]
liver BLK
Mean 0.776
Standard deviation 0.59
Values 0.7 0.24 1.6 0.54
[99]
ref_hepatocyte PTPN22
Mean 0.0981
Standard deviation 0.2
Values 0 0.45 0.043 0 0
[100]
HepG2 PTPN22
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[101]
HepG2.C3A PTPN22
Mean 0.0151
Standard deviation 0.0062
Values 0.011 0.019
[102]
HuH.7 PTPN22
Mean 0.0213
Standard deviation 0.0061
Values 0.028 0.019 0.016
[103]
SNU475 PTPN22
Mean 0.0973
Standard deviation 0.092
Values 0.16 0.032
[104]
THLE PTPN22
Mean 5.46
Standard deviation 1.6
Values 6.6 4.3
[105]
liver PTPN22
Mean 0.925
Standard deviation 0.25
Values 1.2 1.1 0.71 0.72
[106]
ref_hepatocyte FCRL3
Mean 0.026
Standard deviation 0.058
Values 0 0.13 0 0 0
[107]
HepG2 FCRL3
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A FCRL3
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 FCRL3
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 FCRL3
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE FCRL3
Mean 0
Standard deviation 0
Values 0 0
[112]
liver FCRL3
Mean 0.206
Standard deviation 0.091
Values 0.15 0.11 0.31 0.26
[113]
ref_hepatocyte PADI4
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[114]
HepG2 PADI4
Mean 0.173
Standard deviation 0.23
Values 0.013 0.33
[115]
HepG2.C3A PADI4
Mean 0.0248
Standard deviation 0.02
Values 0.011 0.039
[116]
HuH.7 PADI4
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 PADI4
Mean 0.00253
Standard deviation 0.0036
Values 0.0051 0
[118]
THLE PADI4
Mean 0
Standard deviation 0
Values 0 0
[119]
liver PADI4
Mean 0.339
Standard deviation 0.12
Values 0.42 0.26 0.21 0.46
[120]
ref_hepatocyte CTLA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 CTLA4
Mean 0.00788
Standard deviation 0.0051
Values 0.0043 0.011
[122]
HepG2.C3A CTLA4
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[123]
HuH.7 CTLA4
Mean 0.00487
Standard deviation 0.0043
Values 0 0.0064 0.0082
[124]
SNU475 CTLA4
Mean 0
Standard deviation 0
Values 0 0
[125]
THLE CTLA4
Mean 0.0361
Standard deviation 0.0092
Values 0.03 0.043
[126]
liver CTLA4
Mean 0.0171
Standard deviation 0.02
Values 0.04 0.029 0 0