WP_GDNFRET_SIGNALING_AXIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CTNNB1 Catenin beta-1 [1] 0.29[2] 0.36[3] 0.60[4] -0.57[5] 0.38[6] 0.04[7]
2 HSPB11 Intraflagellar transport protein 25 homolog [8] -2.67[9] -2.28[10] -3.13[11] -2.68[12] -1.84[13] -3.25[14]
3 IFT27 Intraflagellar transport protein 27 homolog [15] -7.65[16] [17] -2.76[18] -3.54[19] -2.10[20] -2.09[21]
4 SALL1 Sal-like protein 1 [22] -0.31[23] -9.12[24] -0.10[25] -5.84[26] -2.27[27] 0.58[28]
5 GFRA1 GDNF family receptor alpha-1 [29] -10.68[30] -8.70[31] -0.33[32] -0.45[33] -6.47[34] 1.99[35]
6 BMP4 Bone morphogenetic protein 4 [36] 3.16[37] 2.96[38] -0.76[39] 0.67[40] -0.74[41] -2.25[42]
7 SPRY1 Protein sprouty homolog 1 [43] 0.92[44] 2.35[45] 1.38[46] -0.99[47] 1.46[48] 1.00[49]
8 RET Proto-oncogene tyrosine-protein kinase receptor Ret [50] -6.89[51] -7.60[52] [53] -7.30[54] -3.61[55] -0.47[56]
9 GREM1 Gremlin-1 [57] -3.51[58] -4.80[59] -3.88[60] 6.50[61] 3.44[62] -0.61[63]
10 FAT4 Protocadherin Fat 4 [64] -1.45[65] -1.11[66] 1.40[67] -1.58[68] 4.43[69] 5.39[70]
11 FOXC1 Forkhead box protein C1 [71] 1.89[72] 0.32[73] 1.10[74] 2.03[75] 3.02[76] -1.52[77]
12 GATA3 Trans-acting T-cell-specific transcription factor GATA-3 [78] -5.51[79] [80] 1.31[81] -0.02[82] 0.83[83] 0.15[84]
13 SLIT2 Slit homolog 2 protein [85] -2.57[86] -5.93[87] -1.59[88] 0.85[89] 1.05[90] 1.93[91]
14 GDNF Glial cell line-derived neurotrophic factor [92] 3.63[93] 2.30[94] -4.19[95] -2.64[96] -0.01[97] -1.20[98]
15 SOX11 Transcription factor SOX-11 [99] [100] [101] [102] -5.22[103] -4.51[104] 1.93[105]
16 GLI3 Transcriptional activator GLI3 [106] -2.55[107] [108] -1.67[109] 7.61[110] 6.70[111] 3.09[112]
17 SOX17 Transcription factor SOX-17 [113] [114] [115] [116] 2.32[117] 5.16[118] 4.35[119]
18 ROBO2 Roundabout homolog 2 [120] -3.71[121] [122] 6.80[123] -1.27[124] -0.22[125] 5.15[126]
19 EYA1 Eyes absent homolog 1 [127] [128] [129] [130] [131] [132] [133]
20 LHX1 LIM/homeobox protein Lhx1 [134] [135] [136] [137] [138] [139] [140]
21 FOXC2 Forkhead box protein C2 [141] [142] [143] [144] [145] [146] [147]
22 PAX2 Paired box protein Pax-2 [148] [149] [150] [151] [152] [153] [154]
23 AGTR2 Type-2 angiotensin II receptor [155] [156] [157] [158] [159] [160] [161]
[1]
ref_hepatocyte CTNNB1
Mean 37.2
Standard deviation 16
Values 22 31 23 57 53
[2]
HepG2 CTNNB1
Mean 252
Standard deviation 27
Values 2.7e+02 2.3e+02
[3]
HepG2.C3A CTNNB1
Mean 158
Standard deviation 34
Values 1.8e+02 1.3e+02
[4]
HuH.7 CTNNB1
Mean 282
Standard deviation 64
Values 3.1e+02 2.1e+02 3.3e+02
[5]
SNU475 CTNNB1
Mean 115
Standard deviation 10
Values 1.1e+02 1.2e+02
[6]
THLE CTNNB1
Mean 151
Standard deviation 19
Values 1.4e+02 1.6e+02
[7]
liver CTNNB1
Mean 114
Standard deviation 15
Values 1.1e+02 1.3e+02 98 1.2e+02
[8]
ref_hepatocyte HSPB11
Mean 16.9
Standard deviation 7.3
Values 22 21 23 8.1 9.8
[9]
HepG2 HSPB11
Mean 14.8
Standard deviation 4
Values 18 12
[10]
HepG2.C3A HSPB11
Mean 11.5
Standard deviation 6.1
Values 16 7.2
[11]
HuH.7 HSPB11
Mean 9.63
Standard deviation 3.6
Values 14 6.5 8.8
[12]
SNU475 HSPB11
Mean 12.2
Standard deviation 1.1
Values 11 13
[13]
THLE HSPB11
Mean 14.7
Standard deviation 1.3
Values 14 16
[14]
liver HSPB11
Mean 5.27
Standard deviation 5.4
Values 0.97 0.86 12 7.4
[15]
ref_hepatocyte IFT27
Mean 4.96
Standard deviation 4.3
Values 3.2 9.3 9.7 0 2.6
[16]
HepG2 IFT27
Mean 0.137
Standard deviation 0.09
Values 0.073 0.2
[17]
HepG2.C3A IFT27
Mean 0
Standard deviation 0
Values 0 0
[18]
HuH.7 IFT27
Mean 3.66
Standard deviation 0.61
Values 4.3 3.6 3.1
[19]
SNU475 IFT27
Mean 1.96
Standard deviation 0.75
Values 1.4 2.5
[20]
THLE IFT27
Mean 3.62
Standard deviation 0.35
Values 3.4 3.9
[21]
liver IFT27
Mean 3.47
Standard deviation 3.1
Values 0.93 1 4.6 7.3
[22]
ref_hepatocyte SALL1
Mean 3.42
Standard deviation 1.6
Values 2.9 4.4 5.5 3.2 1.2
[23]
HepG2 SALL1
Mean 15.3
Standard deviation 0.65
Values 16 15
[24]
HepG2.C3A SALL1
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[25]
HuH.7 SALL1
Mean 16
Standard deviation 5
Values 12 21 15
[26]
SNU475 SALL1
Mean 0.275
Standard deviation 0.28
Values 0.48 0.074
[27]
THLE SALL1
Mean 2.22
Standard deviation 0.46
Values 2.5 1.9
[28]
liver SALL1
Mean 15.3
Standard deviation 9.1
Values 14 7.5 28 11
[29]
ref_hepatocyte GFRA1
Mean 3.18
Standard deviation 2.8
Values 1.8 3.5 3.1 0 7.6
[30]
HepG2 GFRA1
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[31]
HepG2.C3A GFRA1
Mean 0.0253
Standard deviation 0.0055
Values 0.021 0.029
[32]
HuH.7 GFRA1
Mean 12.6
Standard deviation 2.7
Values 12 11 16
[33]
SNU475 GFRA1
Mean 10.8
Standard deviation 9.2
Values 4.2 17
[34]
THLE GFRA1
Mean 0.112
Standard deviation 0.0084
Values 0.12 0.11
[35]
liver GFRA1
Mean 37.5
Standard deviation 15
Values 55 34 41 20
[36]
ref_hepatocyte BMP4
Mean 1.73
Standard deviation 3
Values 0 0.61 0.57 7.1 0.41
[37]
HepG2 BMP4
Mean 85.8
Standard deviation 17
Values 74 98
[38]
HepG2.C3A BMP4
Mean 44.8
Standard deviation 2.6
Values 43 47
[39]
HuH.7 BMP4
Mean 5.11
Standard deviation 0.75
Values 5.7 4.3 5.3
[40]
SNU475 BMP4
Mean 12.8
Standard deviation 5.7
Values 8.7 17
[41]
THLE BMP4
Mean 3.25
Standard deviation 0.32
Values 3 3.5
[42]
liver BMP4
Mean 1.08
Standard deviation 0.61
Values 0.65 0.47 1.6 1.6
[43]
ref_hepatocyte SPRY1
Mean 0.868
Standard deviation 0.85
Values 0.51 0.79 0.41 2.4 0.27
[44]
HepG2 SPRY1
Mean 9.07
Standard deviation 0.37
Values 8.8 9.3
[45]
HepG2.C3A SPRY1
Mean 14.6
Standard deviation 0.14
Values 15 15
[46]
HuH.7 SPRY1
Mean 11.3
Standard deviation 4
Values 14 6.7 13
[47]
SNU475 SPRY1
Mean 2.02
Standard deviation 1.1
Values 2.8 1.3
[48]
THLE SPRY1
Mean 7.46
Standard deviation 1.7
Values 8.6 6.3
[49]
liver SPRY1
Mean 5.16
Standard deviation 2.8
Values 3.2 3.3 9.2 5
[50]
ref_hepatocyte RET
Mean 0.569
Standard deviation 0.57
Values 0.5 1.2 1.2 0 0.028
[51]
HepG2 RET
Mean 0.0265
Standard deviation 0.019
Values 0.013 0.04
[52]
HepG2.C3A RET
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[53]
HuH.7 RET
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 RET
Mean 0.0167
Standard deviation 0.0092
Values 0.01 0.023
[55]
THLE RET
Mean 0.145
Standard deviation 0.062
Values 0.19 0.1
[56]
liver RET
Mean 1.22
Standard deviation 1.2
Values 0.4 2 0 2.4
[57]
ref_hepatocyte GREM1
Mean 0.352
Standard deviation 0.29
Values 0.74 0.15 0.54 0 0.33
[58]
HepG2 GREM1
Mean 0.171
Standard deviation 0.09
Values 0.11 0.23
[59]
HepG2.C3A GREM1
Mean 0.0419
Standard deviation 0.032
Values 0.064 0.019
[60]
HuH.7 GREM1
Mean 0.119
Standard deviation 0.092
Values 0.019 0.2 0.14
[61]
SNU475 GREM1
Mean 147
Standard deviation 51
Values 1.1e+02 1.8e+02
[62]
THLE GREM1
Mean 11.9
Standard deviation 0.99
Values 11 13
[63]
liver GREM1
Mean 0.687
Standard deviation 0.75
Values 1.4 0 1.3 0.077
[64]
ref_hepatocyte FAT4
Mean 0.164
Standard deviation 0.12
Values 0.18 0.29 0.086 0 0.27
[65]
HepG2 FAT4
Mean 0.334
Standard deviation 0.24
Values 0.5 0.17
[66]
HepG2.C3A FAT4
Mean 0.252
Standard deviation 0.068
Values 0.3 0.2
[67]
HuH.7 FAT4
Mean 2.16
Standard deviation 1.5
Values 0.81 3.8 1.9
[68]
SNU475 FAT4
Mean 0.254
Standard deviation 0.073
Values 0.2 0.31
[69]
THLE FAT4
Mean 11.1
Standard deviation 0.51
Values 11 11
[70]
liver FAT4
Mean 20.5
Standard deviation 16
Values 35 34 7.6 5
[71]
ref_hepatocyte FOXC1
Mean 0.155
Standard deviation 0.24
Values 0.13 0.065 0 0.58 0
[72]
HepG2 FOXC1
Mean 3.18
Standard deviation 1.3
Values 2.3 4.1
[73]
HepG2.C3A FOXC1
Mean 0.642
Standard deviation 0.12
Values 0.73 0.55
[74]
HuH.7 FOXC1
Mean 1.66
Standard deviation 0.62
Values 1.1 2.3 1.5
[75]
SNU475 FOXC1
Mean 2.91
Standard deviation 0.11
Values 3 2.8
[76]
THLE FOXC1
Mean 3.92
Standard deviation 0.0028
Values 3.9 3.9
[77]
liver FOXC1
Mean 0.161
Standard deviation 0.093
Values 0.29 0.086 0.16 0.1
[78]
ref_hepatocyte GATA3
Mean 0.112
Standard deviation 0.16
Values 0.22 0.34 0 0 0
[79]
HepG2 GATA3
Mean 0.0136
Standard deviation 0.013
Values 0.0043 0.023
[80]
HepG2.C3A GATA3
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 GATA3
Mean 1.39
Standard deviation 0.25
Values 1.1 1.6 1.5
[82]
SNU475 GATA3
Mean 0.511
Standard deviation 0.53
Values 0.89 0.13
[83]
THLE GATA3
Mean 0.623
Standard deviation 0.11
Values 0.7 0.55
[84]
liver GATA3
Mean 0.37
Standard deviation 0.37
Values 0.026 0.11 0.52 0.82
[85]
ref_hepatocyte SLIT2
Mean 0.099
Standard deviation 0.14
Values 0.28 0 0 0 0.21
[86]
HepG2 SLIT2
Mean 0.0923
Standard deviation 0.04
Values 0.064 0.12
[87]
HepG2.C3A SLIT2
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[88]
HuH.7 SLIT2
Mean 0.164
Standard deviation 0.11
Values 0.12 0.29 0.082
[89]
SNU475 SLIT2
Mean 0.824
Standard deviation 0.57
Values 1.2 0.42
[90]
THLE SLIT2
Mean 0.639
Standard deviation 0.075
Values 0.59 0.69
[91]
liver SLIT2
Mean 1.12
Standard deviation 0.57
Values 1.9 1.2 0.63 0.74
[92]
ref_hepatocyte GDNF
Mean 0.0784
Standard deviation 0.058
Values 0.054 0.041 0.043 0.18 0.075
[93]
HepG2 GDNF
Mean 5.37
Standard deviation 1.5
Values 4.3 6.4
[94]
HepG2.C3A GDNF
Mean 1.28
Standard deviation 0.43
Values 0.98 1.6
[95]
HuH.7 GDNF
Mean 0.0214
Standard deviation 0.037
Values 0 0.064 0
[96]
SNU475 GDNF
Mean 0.0579
Standard deviation 0.069
Values 0.11 0.0093
[97]
THLE GDNF
Mean 0.244
Standard deviation 0.074
Values 0.3 0.19
[98]
liver GDNF
Mean 0.102
Standard deviation 0.074
Values 0.21 0.071 0.047 0.077
[99]
ref_hepatocyte SOX11
Mean 0.0409
Standard deviation 0.068
Values 0.16 0.033 0 0.012 0
[100]
HepG2 SOX11
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A SOX11
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 SOX11
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 SOX11
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[104]
THLE SOX11
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[105]
liver SOX11
Mean 0.463
Standard deviation 0.16
Values 0.37 0.3 0.54 0.64
[106]
ref_hepatocyte GLI3
Mean 0.0152
Standard deviation 0.021
Values 0.043 0.033 0 0 0
[107]
HepG2 GLI3
Mean 0.0143
Standard deviation 0.02
Values 0 0.029
[108]
HepG2.C3A GLI3
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 GLI3
Mean 0.0238
Standard deviation 0.021
Values 0 0.039 0.033
[110]
SNU475 GLI3
Mean 13.7
Standard deviation 1.2
Values 13 14
[111]
THLE GLI3
Mean 4.94
Standard deviation 1.2
Values 4.1 5.8
[112]
liver GLI3
Mean 0.384
Standard deviation 0.18
Values 0.42 0.37 0.59 0.15
[113]
ref_hepatocyte SOX17
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[114]
HepG2 SOX17
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A SOX17
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 SOX17
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 SOX17
Mean 0.149
Standard deviation 0.2
Values 0.29 0.0046
[118]
THLE SOX17
Mean 0.727
Standard deviation 0.4
Values 0.44 1
[119]
liver SOX17
Mean 0.395
Standard deviation 0.28
Values 0.71 0.53 0.24 0.1
[120]
ref_hepatocyte ROBO2
Mean 0.00507
Standard deviation 0.0077
Values 0 0.0081 0.017 0 0
[121]
HepG2 ROBO2
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[122]
HepG2.C3A ROBO2
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 ROBO2
Mean 2.82
Standard deviation 2.7
Values 0.9 5.9 1.6
[124]
SNU475 ROBO2
Mean 0.00971
Standard deviation 0.00061
Values 0.01 0.0093
[125]
THLE ROBO2
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[126]
liver ROBO2
Mean 0.537
Standard deviation 0.38
Values 0.99 0.7 0.33 0.13
[127]
ref_hepatocyte EYA1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 EYA1
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[129]
HepG2.C3A EYA1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[130]
HuH.7 EYA1
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 EYA1
Mean 0.411
Standard deviation 0.13
Values 0.5 0.32
[132]
THLE EYA1
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[133]
liver EYA1
Mean 0.265
Standard deviation 0.12
Values 0.21 0.37 0.12 0.36
[134]
ref_hepatocyte LHX1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 LHX1
Mean 0.0938
Standard deviation 0.0052
Values 0.09 0.097
[136]
HepG2.C3A LHX1
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[137]
HuH.7 LHX1
Mean 0.134
Standard deviation 0.052
Values 0.094 0.19 0.11
[138]
SNU475 LHX1
Mean 0.623
Standard deviation 0.029
Values 0.64 0.6
[139]
THLE LHX1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[140]
liver LHX1
Mean 0.0341
Standard deviation 0.04
Values 0.079 0.057 0 0
[141]
ref_hepatocyte FOXC2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 FOXC2
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[143]
HepG2.C3A FOXC2
Mean 0.0146
Standard deviation 0.021
Values 0 0.029
[144]
HuH.7 FOXC2
Mean 0.0146
Standard deviation 0.02
Values 0.037 0.0064 0
[145]
SNU475 FOXC2
Mean 0.127
Standard deviation 0.11
Values 0.2 0.051
[146]
THLE FOXC2
Mean 1.47
Standard deviation 0.083
Values 1.4 1.5
[147]
liver FOXC2
Mean 0
Standard deviation 0
Values 0 0 0 0
[148]
ref_hepatocyte PAX2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 PAX2
Mean 0.0222
Standard deviation 0.025
Values 0.0043 0.04
[150]
HepG2.C3A PAX2
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 PAX2
Mean 0.0138
Standard deviation 0.017
Values 0.0094 0.032 0
[152]
SNU475 PAX2
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[153]
THLE PAX2
Mean 0
Standard deviation 0
Values 0 0
[154]
liver PAX2
Mean 0.00642
Standard deviation 0.013
Values 0 0 0 0.026
[155]
ref_hepatocyte AGTR2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 AGTR2
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A AGTR2
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 AGTR2
Mean 0.0783
Standard deviation 0.054
Values 0.1 0.12 0.016
[159]
SNU475 AGTR2
Mean 0
Standard deviation 0
Values 0 0
[160]
THLE AGTR2
Mean 0
Standard deviation 0
Values 0 0
[161]
liver AGTR2
Mean 0
Standard deviation 0
Values 0 0 0 0