WP_GAMMAGLUTAMYL_CYCLE_FOR_THE_BIOSYNTHESIS_AND_DEGRADATION_OF_GLUTATHIONE_INCLUDING_DISEASES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GCLC Glutamate--cysteine ligase catalytic subunit [1] -0.18[2] 0.19[3] -0.58[4] 1.01[5] -0.27[6] 0.34[7]
2 GGCT Gamma-glutamylcyclotransferase [8] -1.78[9] -0.99[10] 0.52[11] -1.39[12] 0.06[13] -2.24[14]
3 GSS Glutathione synthetase [15] 0.87[16] 0.60[17] 0.38[18] 0.39[19] 1.22[20] -0.32[21]
4 GGT1 Glutathione hydrolase 1 proenzyme [22] -0.50[23] -0.75[24] -0.54[25] -2.12[26] -5.23[27] 0.64[28]
5 OPLAH 5-oxoprolinase [29] 1.11[30] 1.18[31] 0.09[32] -0.36[33] -0.97[34] 1.60[35]
6 DPEP1 Dipeptidase 1 [36] 2.05[37] 0.36[38] -5.91[39] -6.99[40] -7.75[41] -4.21[42]
7 GGTLC2 Glutathione hydrolase light chain 2 [43] [44] [45] -7.25[46] -7.45[47] -7.30[48] -7.44[49]
8 GGTLC1 Glutathione hydrolase light chain 1 [50] -3.15[51] -0.52[52] -0.18[53] -1.27[54] [55] 0.36[56]
9 GGT2 Inactive glutathione hydrolase 2 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte GCLC
Mean 23.9
Standard deviation 11
Values 36 37 16 14 17
[2]
HepG2 GCLC
Mean 41.2
Standard deviation 0.21
Values 41 41
[3]
HepG2.C3A GCLC
Mean 47.1
Standard deviation 0.68
Values 47 48
[4]
HuH.7 GCLC
Mean 19.4
Standard deviation 7.4
Values 15 28 15
[5]
SNU475 GCLC
Mean 84.8
Standard deviation 9.1
Values 78 91
[6]
THLE GCLC
Mean 14.4
Standard deviation 0.55
Values 15 14
[7]
liver GCLC
Mean 45.3
Standard deviation 20
Values 64 59 37 22
[8]
ref_hepatocyte GGCT
Mean 22.9
Standard deviation 5.2
Values 25 17 18 29 25
[9]
HepG2 GGCT
Mean 13.1
Standard deviation 2.8
Values 15 11
[10]
HepG2.C3A GGCT
Mean 19.9
Standard deviation 7.3
Values 25 15
[11]
HuH.7 GGCT
Mean 40
Standard deviation 16
Values 55 23 42
[12]
SNU475 GGCT
Mean 15.4
Standard deviation 3.1
Values 18 13
[13]
THLE GGCT
Mean 17.5
Standard deviation 1.8
Values 16 19
[14]
liver GGCT
Mean 7.28
Standard deviation 5.4
Values 1.9 3.4 11 13
[15]
ref_hepatocyte GSS
Mean 17.2
Standard deviation 2.6
Values 20 17 20 14 16
[16]
HepG2 GSS
Mean 61.8
Standard deviation 7.1
Values 67 57
[17]
HepG2.C3A GSS
Mean 45
Standard deviation 7.3
Values 50 40
[18]
HuH.7 GSS
Mean 27.4
Standard deviation 7
Values 34 20 27
[19]
SNU475 GSS
Mean 39.8
Standard deviation 5.9
Values 36 44
[20]
THLE GSS
Mean 29.3
Standard deviation 2.5
Values 27 31
[21]
liver GSS
Mean 20.8
Standard deviation 9.9
Values 11 14 26 32
[22]
ref_hepatocyte GGT1
Mean 15.1
Standard deviation 12
Values 4.1 22 29 0.7 20
[23]
HepG2 GGT1
Mean 20.9
Standard deviation 6.9
Values 16 26
[24]
HepG2.C3A GGT1
Mean 15.5
Standard deviation 4.3
Values 12 19
[25]
HuH.7 GGT1
Mean 12.7
Standard deviation 3.6
Values 9.9 17 11
[26]
SNU475 GGT1
Mean 6.1
Standard deviation 1.7
Values 4.9 7.3
[27]
THLE GGT1
Mean 0.294
Standard deviation 0.0057
Values 0.29 0.3
[28]
liver GGT1
Mean 35.2
Standard deviation 23
Values 21 15 65 40
[29]
ref_hepatocyte OPLAH
Mean 4.64
Standard deviation 4.4
Values 1.9 11 7.2 2.4 0.7
[30]
HepG2 OPLAH
Mean 19.7
Standard deviation 2.6
Values 18 22
[31]
HepG2.C3A OPLAH
Mean 18.1
Standard deviation 9.1
Values 12 25
[32]
HuH.7 OPLAH
Mean 6.03
Standard deviation 0.25
Values 6.2 5.7 6.2
[33]
SNU475 OPLAH
Mean 6.37
Standard deviation 3.8
Values 3.7 9.1
[34]
THLE OPLAH
Mean 1.73
Standard deviation 0.08
Values 1.7 1.8
[35]
liver OPLAH
Mean 21
Standard deviation 13
Values 40 19 14 10
[36]
ref_hepatocyte DPEP1
Mean 1.57
Standard deviation 3.4
Values 0 0.098 0.17 7.6 0
[37]
HepG2 DPEP1
Mean 12.8
Standard deviation 5.1
Values 16 9.2
[38]
HepG2.C3A DPEP1
Mean 3.47
Standard deviation 0.61
Values 3 3.9
[39]
HuH.7 DPEP1
Mean 0.032
Standard deviation 0.0059
Values 0.037 0.026 0.033
[40]
SNU475 DPEP1
Mean 0.0217
Standard deviation 0.0021
Values 0.02 0.023
[41]
THLE DPEP1
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[42]
liver DPEP1
Mean 0.127
Standard deviation 0.17
Values 0.079 0.029 0.38 0.026
[43]
ref_hepatocyte GGTLC2
Mean 1.21
Standard deviation 2.2
Values 0 5.1 0.99 0 0
[44]
HepG2 GGTLC2
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A GGTLC2
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 GGTLC2
Mean 0.00975
Standard deviation 0.0086
Values 0 0.013 0.016
[47]
SNU475 GGTLC2
Mean 0.0122
Standard deviation 0.0042
Values 0.015 0.0093
[48]
THLE GGTLC2
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[49]
liver GGTLC2
Mean 0.0104
Standard deviation 0.014
Values 0.013 0.029 0 0
[50]
ref_hepatocyte GGTLC1
Mean 0.013
Standard deviation 0.029
Values 0 0.065 0 0 0
[51]
HepG2 GGTLC1
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[52]
HepG2.C3A GGTLC1
Mean 0.0156
Standard deviation 0.0083
Values 0.021 0.0097
[53]
HuH.7 GGTLC1
Mean 0.014
Standard deviation 0.013
Values 0 0.026 0.016
[54]
SNU475 GGTLC1
Mean 0.00949
Standard deviation 0.0063
Values 0.0051 0.014
[55]
THLE GGTLC1
Mean 0
Standard deviation 0
Values 0 0
[56]
liver GGTLC1
Mean 0.025
Standard deviation 0.016
Values 0.013 0.014 0.047 0.026
[57]
ref_hepatocyte GGT2
Missing
[58]
HepG2 GGT2
Missing
[59]
HepG2.C3A GGT2
Missing
[60]
HuH.7 GGT2
Missing
[61]
SNU475 GGT2
Missing
[62]
THLE GGT2
Missing
[63]
liver GGT2
Missing