WP_FOXA2_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GSTA1 Glutathione S-transferase A1 [1] -5.36[2] -9.92[3] -3.33[4] -5.01[5] -9.57[6] -5.98[7]
2 GSTA2 Glutathione S-transferase A2 [8] -6.47[9] -9.75[10] -4.97[11] -6.43[12] -9.71[13] -5.79[14]
3 APOB Apolipoprotein B-100 [15] 2.21[16] 2.20[17] 1.77[18] -4.42[19] -4.10[20] 2.50[21]
4 SLC27A5 Bile acyl-CoA synthetase [22] -5.17[23] -4.70[24] -5.92[25] -4.47[26] -6.71[27] -1.73[28]
5 SLCO1B1 Solute carrier organic anion transporter family member 1B1 [29] -14.90[30] -11.90[31] -6.28[32] -9.33[33] [34] -0.79[35]
6 ABCC2 Canalicular multispecific organic anion transporter 1 [36] 1.11[37] 1.89[38] 0.69[39] 2.77[40] -3.75[41] -0.41[42]
7 SREBF1 Sterol regulatory element-binding protein 1 [43] -0.50[44] -1.00[45] -0.07[46] 1.48[47] 1.92[48] -1.87[49]
8 MTTP Microsomal triglyceride transfer protein large subunit [50] -1.86[51] 0.64[52] 1.99[53] -4.36[54] -3.21[55] -0.52[56]
9 MLXIPL Carbohydrate-responsive element-binding protein [57] -1.59[58] 0.02[59] -1.56[60] -4.95[61] -2.94[62] -0.83[63]
10 FASN Fatty acid synthase [64] 2.67[65] 2.53[66] 3.48[67] 3.75[68] 4.04[69] 0.14[70]
11 ABCC3 Canalicular multispecific organic anion transporter 2 [71] 1.36[72] -0.11[73] -1.36[74] 3.28[75] 2.96[76] 0.28[77]
12 FOXA1 Hepatocyte nuclear factor 3-alpha [78] 0.53[79] -1.38[80] 0.94[81] 2.18[82] -4.69[83] -2.90[84]
13 FOXA2 Hepatocyte nuclear factor 3-beta [85] 0.78[86] 0.31[87] 1.10[88] -4.53[89] -4.89[90] -2.84[91]
14 IRS1 Insulin receptor substrate 1 [92] 2.36[93] 1.03[94] 2.84[95] 4.72[96] 4.56[97] -0.25[98]
15 ACACA Acetyl-CoA carboxylase 1 [99] 2.72[100] 2.29[101] 3.59[102] 5.60[103] 5.05[104] 0.99[105]
16 IRS2 Insulin receptor substrate 2 [106] -5.38[107] [108] -2.92[109] 2.35[110] 6.44[111] 0.02[112]
17 FOXO1 Forkhead box protein O1 [113] 1.96[114] 0.85[115] 1.37[116] 4.19[117] 6.47[118] 0.73[119]
18 ABCC4 Multidrug resistance-associated protein 4 [120] 2.06[121] 0.37[122] 2.99[123] 5.71[124] 5.48[125] -1.89[126]
19 GSTM2 Glutathione S-transferase Mu 2 [127] 0.66[128] -1.37[129] 0.81[130] 4.49[131] 4.10[132] -2.35[133]
20 PPARGC1B Peroxisome proliferator-activated receptor gamma coactivator 1-beta 2.64[134] -2.06[135] 4.09[136] 5.68[137] 6.31[138] 2.58[139]
21 INS Insulin [140] [141] [142] [143] [144] [145] [146]
[1]
ref_hepatocyte GSTA1
Mean 456
Standard deviation 5.8e+02
Values 8.4 1.4e+03 4.8e+02 1.3e+02 2.2e+02
[2]
HepG2 GSTA1
Mean 20.3
Standard deviation 5.9
Values 24 16
[3]
HepG2.C3A GSTA1
Mean 1.31
Standard deviation 0.69
Values 1.8 0.83
[4]
HuH.7 GSTA1
Mean 93.3
Standard deviation 39
Values 1.3e+02 53 95
[5]
SNU475 GSTA1
Mean 3.21
Standard deviation 3.3
Values 0.88 5.5
[6]
THLE GSTA1
Mean 0.127
Standard deviation 0.11
Values 0.21 0.048
[7]
liver GSTA1
Mean 52.8
Standard deviation 52
Values 6.8 29 48 1.3e+02
[8]
ref_hepatocyte GSTA2
Mean 199
Standard deviation 3.4e+02
Values 1.1 8e+02 1.2e+02 27 48
[9]
HepG2 GSTA2
Mean 4.11
Standard deviation 1.5
Values 5.2 3.1
[10]
HepG2.C3A GSTA2
Mean 0.647
Standard deviation 0.13
Values 0.74 0.55
[11]
HuH.7 GSTA2
Mean 13.1
Standard deviation 7.6
Values 10 22 7.6
[12]
SNU475 GSTA2
Mean 0.525
Standard deviation 0.65
Values 0.066 0.98
[13]
THLE GSTA2
Mean 0.0506
Standard deviation 0.0038
Values 0.053 0.048
[14]
liver GSTA2
Mean 26.3
Standard deviation 39
Values 0.29 20 0.73 84
[15]
ref_hepatocyte APOB
Mean 165
Standard deviation 1.5e+02
Values 8.3 3.4e+02 2.2e+02 2.4e+02 15
[16]
HepG2 APOB
Mean 1.41e+03
Standard deviation 6.5e+02
Values 1.9e+03 9.5e+02
[17]
HepG2.C3A APOB
Mean 2.13e+03
Standard deviation 5.8e+02
Values 2.5e+03 1.7e+03
[18]
HuH.7 APOB
Mean 1.16e+03
Standard deviation 4.8e+02
Values 6.1e+02 1.5e+03 1.4e+03
[19]
SNU475 APOB
Mean 1.75
Standard deviation 0.12
Values 1.8 1.7
[20]
THLE APOB
Mean 2.04
Standard deviation 0.96
Values 2.7 1.4
[21]
liver APOB
Mean 6.85e+03
Standard deviation 4.5e+03
Values 8.5e+03 1.2e+04 2.9e+03 3.6e+03
[22]
ref_hepatocyte SLC27A5
Mean 83.6
Standard deviation 1.2e+02
Values 6 2.7e+02 1.4e+02 0.8 1.2
[23]
HepG2 SLC27A5
Mean 4.25
Standard deviation 0.62
Values 3.8 4.7
[24]
HepG2.C3A SLC27A5
Mean 8.96
Standard deviation 1.1
Values 8.2 9.7
[25]
HuH.7 SLC27A5
Mean 2.84
Standard deviation 0.59
Values 3.5 2.7 2.3
[26]
SNU475 SLC27A5
Mean 0.856
Standard deviation 0.043
Values 0.89 0.83
[27]
THLE SLC27A5
Mean 0.169
Standard deviation 0.036
Values 0.2 0.14
[28]
liver SLC27A5
Mean 184
Standard deviation 60
Values 1.6e+02 1.1e+02 2.2e+02 2.5e+02
[29]
ref_hepatocyte SLCO1B1
Mean 35.9
Standard deviation 41
Values 1.4 1e+02 37 0 40
[30]
HepG2 SLCO1B1
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[31]
HepG2.C3A SLCO1B1
Mean 0.0263
Standard deviation 0.023
Values 0.043 0.0097
[32]
HuH.7 SLCO1B1
Mean 0.948
Standard deviation 1.4
Values 0.22 2.6 0.074
[33]
SNU475 SLCO1B1
Mean 0.0127
Standard deviation 0.018
Values 0.025 0
[34]
THLE SLCO1B1
Mean 0
Standard deviation 0
Values 0 0
[35]
liver SLCO1B1
Mean 152
Standard deviation 42
Values 95 1.8e+02 1.8e+02 1.5e+02
[36]
ref_hepatocyte ABCC2
Mean 31.6
Standard deviation 23
Values 16 17 17 68 40
[37]
HepG2 ABCC2
Mean 125
Standard deviation 1.3
Values 1.3e+02 1.2e+02
[38]
HepG2.C3A ABCC2
Mean 328
Standard deviation 1.2
Values 3.3e+02 3.3e+02
[39]
HuH.7 ABCC2
Mean 105
Standard deviation 48
Values 68 1.6e+02 88
[40]
SNU475 ABCC2
Mean 48.9
Standard deviation 12
Values 41 57
[41]
THLE ABCC2
Mean 0.497
Standard deviation 0.041
Values 0.53 0.47
[42]
liver ABCC2
Mean 174
Standard deviation 96
Values 1.9e+02 3e+02 89 1.1e+02
[43]
ref_hepatocyte SREBF1
Mean 27.4
Standard deviation 36
Values 6.5 85 42 1.8 1.2
[44]
HepG2 SREBF1
Mean 35.4
Standard deviation 8.8
Values 29 42
[45]
HepG2.C3A SREBF1
Mean 38.3
Standard deviation 21
Values 24 53
[46]
HuH.7 SREBF1
Mean 53.8
Standard deviation 3.4
Values 56 55 50
[47]
SNU475 SREBF1
Mean 17.3
Standard deviation 4.1
Values 14 20
[48]
THLE SREBF1
Mean 21.9
Standard deviation 0.74
Values 21 22
[49]
liver SREBF1
Mean 54.7
Standard deviation 14
Values 35 59 58 67
[50]
ref_hepatocyte MTTP
Mean 24.5
Standard deviation 20
Values 0.63 44 29 43 6.3
[51]
HepG2 MTTP
Mean 12.3
Standard deviation 2.3
Values 14 11
[52]
HepG2.C3A MTTP
Mean 106
Standard deviation 10
Values 1.1e+02 99
[53]
HuH.7 MTTP
Mean 201
Standard deviation 24
Values 1.8e+02 2.3e+02 1.9e+02
[54]
SNU475 MTTP
Mean 0.27
Standard deviation 0.034
Values 0.29 0.25
[55]
THLE MTTP
Mean 0.56
Standard deviation 0.15
Values 0.67 0.45
[56]
liver MTTP
Mean 125
Standard deviation 22
Values 1.5e+02 1.3e+02 1.3e+02 95
[57]
ref_hepatocyte MLXIPL
Mean 24.5
Standard deviation 24
Values 3.4 54 44 21 0.29
[58]
HepG2 MLXIPL
Mean 14.9
Standard deviation 1.1
Values 16 14
[59]
HepG2.C3A MLXIPL
Mean 69.5
Standard deviation 28
Values 50 89
[60]
HuH.7 MLXIPL
Mean 17.1
Standard deviation 3.9
Values 20 18 13
[61]
SNU475 MLXIPL
Mean 0.18
Standard deviation 0.047
Values 0.15 0.21
[62]
THLE MLXIPL
Mean 0.675
Standard deviation 0.52
Values 1 0.31
[63]
liver MLXIPL
Mean 101
Standard deviation 65
Values 69 43 1.9e+02 99
[64]
ref_hepatocyte FASN
Mean 16.9
Standard deviation 11
Values 11 22 17 31 3.5
[65]
HepG2 FASN
Mean 197
Standard deviation 11
Values 2e+02 1.9e+02
[66]
HepG2.C3A FASN
Mean 273
Standard deviation 1.4e+02
Values 1.7e+02 3.7e+02
[67]
HuH.7 FASN
Mean 387
Standard deviation 1.1e+02
Values 2.9e+02 3.8e+02 5e+02
[68]
SNU475 FASN
Mean 51.5
Standard deviation 12
Values 43 60
[69]
THLE FASN
Mean 59
Standard deviation 19
Values 46 72
[70]
liver FASN
Mean 136
Standard deviation 1e+02
Values 2.8e+02 1.2e+02 92 54
[71]
ref_hepatocyte ABCC3
Mean 14.4
Standard deviation 9.9
Values 5 9.7 31 14 12
[72]
HepG2 ABCC3
Mean 67.6
Standard deviation 20
Values 54 81
[73]
HepG2.C3A ABCC3
Mean 37.4
Standard deviation 7.2
Values 32 42
[74]
HuH.7 ABCC3
Mean 11.6
Standard deviation 4.6
Values 10 17 7.9
[75]
SNU475 ABCC3
Mean 31.8
Standard deviation 16
Values 21 43
[76]
THLE ABCC3
Mean 23.7
Standard deviation 5.8
Values 28 20
[77]
liver ABCC3
Mean 128
Standard deviation 23
Values 1.3e+02 1.4e+02 93 1.5e+02
[78]
ref_hepatocyte FOXA1
Mean 12.4
Standard deviation 11
Values 2.2 10 11 30 8.2
[79]
HepG2 FOXA1
Mean 32.8
Standard deviation 9
Values 39 26
[80]
HepG2.C3A FOXA1
Mean 13.3
Standard deviation 2.2
Values 15 12
[81]
HuH.7 FOXA1
Mean 48.7
Standard deviation 5.6
Values 51 42 53
[82]
SNU475 FOXA1
Mean 12.8
Standard deviation 3.1
Values 11 15
[83]
THLE FOXA1
Mean 0.101
Standard deviation 0.016
Values 0.11 0.09
[84]
liver FOXA1
Mean 12.1
Standard deviation 4.9
Values 14 7 18 9.2
[85]
ref_hepatocyte FOXA2
Mean 7.53
Standard deviation 2.5
Values 8.6 6.8 11 7.1 4.1
[86]
HepG2 FOXA2
Mean 23.7
Standard deviation 12
Values 15 32
[87]
HepG2.C3A FOXA2
Mean 26.1
Standard deviation 10
Values 19 33
[88]
HuH.7 FOXA2
Mean 33.3
Standard deviation 2.6
Values 33 36 31
[89]
SNU475 FOXA2
Mean 0.074
Standard deviation 0.033
Values 0.051 0.097
[90]
THLE FOXA2
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[91]
liver FOXA2
Mean 7.66
Standard deviation 5
Values 5.6 3.8 15 6.3
[92]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[93]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[94]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[95]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[96]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[97]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[98]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[99]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 1.7 2.7 3.2 4.3 3.2
[100]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 40 33
[101]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 32 50
[102]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 57 78 89
[103]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 23 43
[104]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[105]
liver ACACA
Mean 44
Standard deviation 21
Values 50 70 21 35
[106]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 1.4 2.9 5.7 0.019 0.61
[107]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.043 0.14
[108]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.17 1.4 0.2
[110]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.8 2.1
[111]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[112]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 17 11 29 6.3
[113]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 2 2.6 1.9 0.71 1.7
[114]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 14 11
[115]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 7.9 10
[116]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 7.6 10 10
[117]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 6 8.6
[118]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[119]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 29 19 25 13
[120]
ref_hepatocyte ABCC4
Mean 1.25
Standard deviation 1.2
Values 0.52 0.16 0.41 2.7 2.4
[121]
HepG2 ABCC4
Mean 9.57
Standard deviation 0.89
Values 8.9 10
[122]
HepG2.C3A ABCC4
Mean 4.52
Standard deviation 0.047
Values 4.5 4.5
[123]
HuH.7 ABCC4
Mean 20.4
Standard deviation 3.5
Values 16 23 22
[124]
SNU475 ABCC4
Mean 14.9
Standard deviation 1.9
Values 14 16
[125]
THLE ABCC4
Mean 11.8
Standard deviation 2.1
Values 10 13
[126]
liver ABCC4
Mean 2.46
Standard deviation 0.72
Values 3 3.1 2.2 1.6
[127]
ref_hepatocyte GSTM2
Mean 0.961
Standard deviation 0.9
Values 0 1.7 1.3 1.9 0
[128]
HepG2 GSTM2
Mean 2.78
Standard deviation 0.68
Values 3.3 2.3
[129]
HepG2.C3A GSTM2
Mean 1.04
Standard deviation 0.29
Values 0.84 1.2
[130]
HuH.7 GSTM2
Mean 3.46
Standard deviation 0.18
Values 3.7 3.3 3.4
[131]
SNU475 GSTM2
Mean 4.89
Standard deviation 2.9
Values 2.8 7
[132]
THLE GSTM2
Mean 3.5
Standard deviation 0.29
Values 3.7 3.3
[133]
liver GSTM2
Mean 1.38
Standard deviation 0.62
Values 1.3 0.53 1.9 1.8
[134]
ref_hepatocyte PPARGC1B
Mean 0.16
Standard deviation 0.12
Values 0.17 0.11 0.1 0.056 0.35
[135]
HepG2 PPARGC1B
Mean 1.82
Standard deviation 0.5
Values 1.5 2.2
[136]
HepG2.C3A PPARGC1B
Mean 0.107
Standard deviation 0.00023
Values 0.11 0.11
[137]
HuH.7 PPARGC1B
Mean 5.61
Standard deviation 1.8
Values 4.5 4.6 7.7
[138]
SNU475 PPARGC1B
Mean 1.86
Standard deviation 0.018
Values 1.9 1.9
[139]
THLE PPARGC1B
Mean 2.7
Standard deviation 0.41
Values 2.4 3
[140]
liver PPARGC1B
Mean 6.98
Standard deviation 1.2
Values 5.7 8.6 6.9 6.7
[141]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[143]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[145]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[147]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0.28 0.057 0 0